cluster event on personalised medicine with itn funded projects … · 2019-11-29 · maria...

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Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator ERA PerMed National Health School, ISCIII, Madrid, Spain, 6-7 th Nov 2019 Cluster event on Personalised Medicine with ITN funded projects GRANT AGREEMENT NUMBER — 779282 ERA PerMed Horizon 2020

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Page 1: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

Maria Cristina Nieto GarciaNational Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

ERA PerMed

National Health School, ISCIII, Madrid, Spain, 6-7th Nov 2019

Cluster event on Personalised Medicine with ITN funded projects

GRANT AGREEMENTNUMBER — 779282 ERA PerMed

Horizon 2020

Page 2: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

ERA PerMed

JTC2018 (co-funded by EC)

JTC2019

Next calls: JTC2020 & JTC2021

ERAPerMed – Content

Page 3: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

ERAPerMed – Characteristics

32 Partners23 Countries

19 EU countries3 associated countries (to Horizon 2020)Turkey, Norway, Israel1 third country (Canada)

5 regions; Saxony, Quebec, Lombardy, Navarra and Cataluña

Coordination:Instituto de Salud Carlos III(ISCIII), SPAIN

MAIN OBJECTIVES

1 EU Co-funded Call 2018

Joint Transnational Calls (JTCs)

Up to 3 Additional Calls 2019, 2020, 2021

TIME FRAME: 1 December 2017 – 30 November 2022

The biggest ERA Net in health

http://www.erapermed.eu/

Page 4: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

Horizon 2020Call: H2020-SC1-2016-2017

(Personalised Medicine)Topic: SC1-HCO-03-2017

Foster the implementation of ICPerMed Action Plan and SRIA (Strategic Research and Innovation Agenda) by funding transnational research projects in the field of Personalised Medicine (PM)

Alignment of regional and national PM research strategies and funding activities, promoting excellence, reinforcing the competitiveness of Europe and Canada and enhance the European collaboration as well as with countries beyond the European Union.

Action Plan SRIA

https://www.icpermed.eu/

Page 5: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

Definition of Personalised Medicine:

Stated in the Strategic Research and Innovation Agenda(SRIA) of PerMed, adopted from the H2020 advisory group*:

• “Personalised Medicine refers to a medical model usingcharacterisation of individuals’ phenotypes and genotypes(e.g. molecular profiling, medical imaging, lifestyle data) fortailoring the right therapeutic strategy for the right person atthe right time, and/or to determine the predisposition todisease and/or to deliver timely and targeted prevention.”

* European Commission. Advice for 2016/2017 of the Horizon 2020 Advisory Group for Social

Challenge 1, “Health, Demographic Change and Wellbeing

ERAPerMed

Page 6: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

WP1 - COORDINATION & MANAGEMENT

EC cofunded callWP2+WP3+WP4+WP5

WP6 - ADDITIONAL NON COFUNDED CALLS

WP 7 - STRATEGIC SUPPORT ACTIVITIESExternal relationships, relationship with end users and patient

representatives, sustainability and exploitation of results…

ERAPerMed – Structure

Page 7: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

WP 2 - PREPARATION AND LAUNCH OF THE EU CO-FUNDED CALL

WP 3 – EVALUATION & PROPOSAL SELECTION OF THE EU CO-FUNDED CALL

WP 4 - FOLLOW UP AND MONITORING OF THE EU CO-FUNDED PROJECTS

WP 5 - COMMUNICATION AND EXPLOITATION OF RESULTS OF THE EU CO-FUNDED CALL

ERAPerMed – Structure

EC cofunded call

Page 8: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

ERA PerMed – cofunding scheme

7,834,200 €33% of the budget

commitment 1,674,750 €

9,508,950 € Maximum EU contribution

Unitcosts

2,790,337 €6,718,613 €EC cofundedcall

Implementation costs

23,740,000 €

Initial Financial Commitment of ERA PerMed Partners

Page 9: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

ERA PerMed

JTC2018 (co-funded by EC)

JTC2019

Next calls: JTC2020 & JTC2021

ERAPerMed – Content

Page 10: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

ERAPerMed – EU co-funded JTC 2018

30 Partners22 Countries

19 EU countries3 associated countries (to Horizon 2020):

Turkey, Norway, Israel

1 third country: Canada

5 regions

Call Secretariat (JCS)Instituto de Salud Carlos III (ISCIII), SPAIN

Countries´ ex ante Budget 26 M €

Timeline:

Launch: 14th February 2018

Two step procedure

Submission deadline for Pre-proposals: 10th April 2018

Submission deadline for invited Full-proposals: 26th July 2018Expected start of granted projects: 2019 q1

http://www.erapermed.eu/joint-calls/joint-transnational-call-2018/

Page 11: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

Call calendar

Preparation of the JTC2018

JTC2018

December February April June July August

Pre-announcement

Launch

Submission deadline

pre-proposals

CSC meeting

Submissiondeadline

full-proposals

Final funding decision in November 2018

Evaluation 1st stage

Rebuttal phase

Evaluation 2nd stage

September

PRP meeting

20182017

April June July August September December

First conceptExpert

consultationFirst draft of the call text

CAB response on the call text

(Pre-) Final version of the call text

Validation of the call text by

the ECAt least 30 days

before launching

2017

November

Survey on participation /

advanced concept

At least 60 days

Each proposal is allocated to 3 Peer Reviewers for evaluation.

Page 12: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

TOPIC: RESEARCH PROJECTS ON PERSONALISED MEDICINE – SMART COMBINATION OF

PRE-CLINICAL AND CLINICAL RESEARCH WITH DATA AND ICT SOLUTIONS

ERAPerMed – EU co-funded JTC 2018

Scope of the call

Each project proposal MUST address at least one module of both Research Areas 1 and 2.

Page 13: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

Central Eligibility

A) Academia or research institutes;

B) Clinical/public health sector

C) (Industry) Private partners, e.g. SMEs

• Each consortium must involve at least 3 partners eligible

for funding coming from 3 different countries.

• Project coordinator must be eligible to be funded

• The maximum number of partners per project is 6

(7 if underrepresented)

• No more than two partners from the same country.

• No more than one partner with its own funding is allowed.

* Each FO has its own national/regional eligibility criteria

ERA PerMed JTC 2018

Page 14: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

Partnering Tool

https://partnering.pt-dlr.de/ICPerMed

Page 15: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

ERAPerMed – EU co-funded JTC 2018

Pre-proposal Coordinators and Partners per Country

Page 16: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

ERAPerMed – EU co-funded JTC 2018

Pre-proposal Request of Funding per Country

Page 17: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

ERAPerMed – EU co-funded JTC 2018

Type of Applicant Beneficiary Entity in Pre-proposals

Page 18: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

ERAPerMed – EU co-funded JTC 2018

Page 19: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

ERAPerMed – EU co-funded JTC 2018 Facts and Figures

• Pre-proposal stage:

• 159/143 submitted projects

• 741 partners requesting to 30 funding organisations

• 176.21 M € requested funding

• 50 Pre-proposals invited to submit a Full proposal

• 75 evaluators from institutions affiliated to 24 countries (25% females)

• Full proposal stage:

• 50 submitted projects

• 25 Proposals funded, 131 partners requesting to 21 funding organisations.

• 28.27 M € requested funding

• 23 evaluators from institutions affiliated to 15 countries

Page 20: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

ERA PerMed

JTC2018 (co-funded by EC)

JTC2019

Next calls: JTC2020 & JTC2021

ERAPerMed – Content

Page 21: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

30 Partners22 Countries

17 EU countries3 associated countries (to Horizon 2020):

Turkey, Norway, Israel

2 third countries: Canada and Egypt

6 regions (Saxony, Quebec, Lombardy,

Navarra ,Cataluña and Tuscany

1 charity: AECC

Call Secretariat (JCS)Agence National de la Recherche (ANR)FRANCE Countries´ ex ante Budget

31.42 M €Two step procedure

Timeline:

Launch: 9th January 2019Submission deadline for Pre-proposals: 7th March 2019

Submission deadline for invited Full-proposals: 17th June 2019

http://www.erapermed.eu/joint-transnational-call-2019/

ERAPerMed – non EU co-funded JTC 2019

Page 22: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

ERAPerMed – non EU co-funded JTC 2019

Scope of the call

TOPIC: PERSONALIZED MEDICINE: MULTIDISCIPLINARY RESEARCH TOWARDS IMPLEMENTATION

Each project proposal MUST address at least one module of Research Area 3 and at least one module of Research Area 1 or 2.

Page 23: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

Submitted pre-proposals – N° partners/coordinators

4

3

5

7

8

7

8

9

11

10

13

11

14

10

17

17

16

27

26

25

21

26

34

34

33

27

49

43

39

86

97

0

2

1

1

0

1

2

2

2

3

1

4

1

7

2

3

9

0

2

3

13

10

4

6

15

23

3

15

25

14

22

0 20 40 60 80 100 120

CDTI

ASRT

FNR

FRQS

TUBITAK

VIAA

MSE

F.R.S.-FNRS

BMG/VDI

TuscReg

HRB

GN

NKFIH

SMWK

CIHR

RCN

CSO-MOH

no funding request

InnoFond

NCBR

AKA

UEFISCDI

DS-CAT

FWF

ISCIII/AECC-FC

IT-MoH

SRC

GSRT

FRRB

ANR

BMBF/DLR

Partner

Coordinator

Page 24: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

Submitted pre-proposals – budget requested

38840 483,00 €

24578 937,00 €

18174 737,00 €

16544 040,00 €

11104 420,00 €

10384 314,00 €

9917 828,00 €

9168 782,00 €

8608 192,00 €

7636 561,00 €

7262 921,00 €

6624 952,00 €

5866 548,00 €

5109 993,00 €

4322 676,00 €

3616 365,00 €

3588 005,00 €

3442 102,00 €

3401 977,00 €

3121 934,00 €

2357 042,00 €

2205 592,00 €

2066 203,00 €

1908 913,00 €

1655 437,00 €

1455 347,00 €

1199 175,00 €

939 300,00 €

823 802,00 €

567 000,00 €

0,00 € 5000 000,00 € 10000 000,00 € 15000 000,00 € 20000 000,00 € 25000 000,00 € 30000 000,00 € 35000 000,00 € 40000 000,00 € 45000 000,00 €

BMBF/DLR

ANR

FRRB

SRC

IT-MoH

FWF

GSRT

InnoFond

ISCIII/AECC-FC

AKA

DS-CAT

SMWK

UEFISCDI

RCN

NCBR

CIHR

CSO-MOH

HRB

BMG/VDI

GN

TuscReg

FRQS

NKFIH

F.R.S.-FNRS

FNR

VIAA

MSE

TUBITAK

CDTI

ASRT

Page 25: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

ERAPerMed –non EU co-funded JTC 2019 Facts and Figures

• Pre-proposal stage:

• 196 submitted projects

• 906 partners requesting to 30 funding organisations (27 own funding)

• 216 M € requested funding

• 56 Pre-proposals invited to submit a Full proposal

• 102 evaluators from institutions affiliated to 26 countries (33% females)

• Full proposal stage:

• 56 submitted projects

• 22 Proposals expected to be funded, 108 partners requesting to 24

funding organisations (5 partners on own funding).

• 24.6 M € requested funding

• 29 evaluators from institutions affiliated to 17 countries

Page 26: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

ERA PerMed

JTC2018 (co-funded by EC)

JTC2019

Next calls: JTC2020 & JTC2021

ERAPerMed – Content

Page 27: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

31 Partners 22 Countries

17 EU countries2 associated countries (to Horizon 2020):Norway, Israel3 third countries: Canada, Egypt, Panama6 regions (Saxony, Quebec, Lombardy,

Navarra, Cataluña and Tuscany)1 charity: AECC

Call Secretariat (JCS)

German Aerospace Center (DLR)GERMANY [email protected] Countries´ ex ante Budget

24.6 M € approx.

Two step procedure

Timeline expected:

Launch: December 2019Submission deadline for Pre-proposals: March 2020

Submission deadline for invited Full-proposals: June 2020

ERAPerMed – non EU co-funded JTC 2020

http://www.erapermed.eu/wp-content/uploads/2019/11/ERA-PerMed_JTC2020_pre-announcement_final.pdf

Page 28: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

ERAPerMed – non EU co-funded JTC 2020

Scope of the call

TOPIC: “PERSONALISED MEDICINE – PRE-/CLINICAL RESEARCH, BIG DATA AND ICT, IMPLEMENTATION AND USER’S PERSPECTIVE”

Each project proposal MUST address at least one module of Research Area 3 and at least one module of Research Area 1 or 2.

Page 29: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

JCS2018: ISCIII- Mauricio García, Candi Sánchez and Cristina Nieto:

[email protected]

JCS2019: ANR- Monika Frenzel and Jeanne Guihot

[email protected]

JCS2020: DLR- Katja Kuhlmann and Alexandra Becker

[email protected]

ERAPerMed – Joint Call Secretariat contact points

Page 30: Cluster event on Personalised Medicine with ITN funded projects … · 2019-11-29 · Maria Cristina Nieto Garcia National Institute of Health Carlos III (ISCIII), ERA PerMed coordinator

Thank you for your attention!

Contact: Maria Cristina Nieto Garcia, PhD <[email protected]>

GRANT AGREEMENTNUMBER — 779282 ERA PerMed

Horizon 2020