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Clinical Investigator Toolbox July 2015 Rachel Walden, MLIS Eskind Biomedical Library Resources and Services

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Page 1: Clinical Investigator Toolbox

Clinical Investigator Toolbox July 2015

Rachel Walden, MLIS

Eskind Biomedical Library Resources and

Services

Page 2: Clinical Investigator Toolbox

Objectives

• Introduce attendees to Eskind Biomedical Library Resources and Services• Provide a refresher on searching• Identify relevant, supplementary resources

on the World Wide Web • H-Index and Journal Impact Factors• Introduction to Standards

Page 3: Clinical Investigator Toolbox

Library Resources & Services

Page 4: Clinical Investigator Toolbox

Why do we Search the Medical Literature?

Patient/ Population

Education

Best Practices

ResearchEvidenceBasedMedicine

Page 5: Clinical Investigator Toolbox

Levels of Evidence

Page 6: Clinical Investigator Toolbox

Resources

• PubMed: http://www.ncbi.nlm.nih.gov/pubmed• National Guidelines Clearinghouse:

http://www.guideline.gov/• Cochrane Library- Database of Systematic Reviews• Clinicaltrials.gov • AHRQ- Agency for Healthcare Research and Quality:

http://www.ahrq.gov/ • Clinical Key• UpToDate• EMBASE

Page 7: Clinical Investigator Toolbox

Resources for Outcomes Research ISPOR Good Practices for Outcomes Research Index:

http://www.ispor.org/workpaper/practices_index.asp• Patient-Centered Outcomes Research Institute:

http://www.pcori.org/

Resource for Human Subject Protection• Office for Human Research Protections (OHRP):

http://www.hhs.gov/ohrp/index.html

Page 8: Clinical Investigator Toolbox

Resources for Biomedical Ethics • Philosopher's Index• Bioethics Information Resources:

http://www.nlm.nih.gov/bsd/bioethics.html• Globethics.net Libraries:

http://www.globethics.net/library/libraries-home• Global Ethics Observatory (GEObs):

http://www.unesco.org/new/en/social-and-human-sciences/themes/global-ethics-observatory/

Page 9: Clinical Investigator Toolbox

Resources for Statistics • local and national Health Departments • Health Information Tennessee: http://hit.state.tn.us/home.aspx • CDC Data and Statistics:

http://www.cdc.gov/DataStatistics/?s_cid=cdc_homepage_topmenu_001• State Health Facts: http://kff.org/statedata/• Partners in Information Access for the Public Health Workforce: http://phpartners.org/• Centers for Medicare and Medicaid Services (CMS): http://www.cms.gov/ • National Center for Health Statistics (NCHS): http://www.cdc.gov/nchs/• HCUPnet: http://hcupnet.ahrq.gov/• TOXNET: http://toxnet.nlm.nih.gov/ • MeasureDHS : www.measuredhs.com• OECD iLibrary:

http://www.oecd-ilibrary.org/statistics;jsessionid=1b9u5w3bldkl6.x-oecd-live-02• United Nations: http://unstats.un.org/unsd/default.htm• World Health Organization Data: http://www.who.int/research/en/ • WHO Statistical Information System (WHOSIS): http://www3.who.int/whosis/menu.cfm• Global Health Facts: http://kff.org/globaldata/

Page 10: Clinical Investigator Toolbox

The H Index“I propose the index h, defined as the number of papers with

citation number ≤ h, as a useful index to calculate the scientific

output of a researcher” .1

“A scientist has index h if h of [his/her] Np papers have at least h

citations each, and the other (Np − h) papers have at most h

citations each.”2

1. Hirsch, J. E. (2005). An index to quantify an individual's scientific research output. Proceedings of the National

Academy of Sciences of the United States of America, 102(46), 16569-16572. doi:10.1073/pnas.0507655102

2. University Library. Measuring Your Impact: Impact Factor, Citation Analysis, and other Metrics. Research and

Subject Guides. Illinois, Chicago: University of Illinois at Chicago; 2015.

Page 11: Clinical Investigator Toolbox

H – Index Example

If an author has 15 papers cited 15 times his or her h-index would be 15. Publications with less than 15 citations do not contribute to the h-index of the author.

Page 12: Clinical Investigator Toolbox

Web of Science h-index analysis

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Limitations of h-index• Can be influenced by self-citations• Does not account for first authors • Looks at quantity versus influence• Dependent on career length• All types of citations are weighted the same:

reviews, books, primary research, etc. • Dependent on the size of the field• H-index for an author varies when calculated by

different resources

Page 14: Clinical Investigator Toolbox

Journal Impact Factor“A journal's impact factor is based on 2 elements: the numerator, which is the number of citations in the current year to items published in the previous 2 years, and the denominator, which is the number of substantive articles and reviews published in the same 2 years.”1

1. Garfield E. The History and Meaning of the Journal Impact Factor. JAMA. 2006;295(1):90-93. doi:10.1001/jama.295.1.90.

Andrew P. Kurmis J Bone Joint Surg Am 2003;85:2449-2454

Page 15: Clinical Investigator Toolbox

Journal Citation Reports From Web of Science

Page 16: Clinical Investigator Toolbox

Limitations of the Impact Factor

• Citations to non- source items may inflate the Impact factor

• Self-citation• Journal impact factor varies when calculated by

different resources• Publishing time penalizes disciplines with longer

turnover times• Review articles heavily cited

Page 17: Clinical Investigator Toolbox

Reporting your Research

• CONSORT• http://www.consort-statement.org/

• PRISMA• http://www.prisma-statement.org/

• STROBE• http://www.strobe-statement.org/

Page 18: Clinical Investigator Toolbox

Contact Information

Rachel [email protected]

Phillip [email protected]

Eskind Biomedical Library615.936.1410http://www.mc.vanderbilt.edu/diglib/

Vanderbilt Libraries615.322.7100http://www.library.vanderbilt.edu/