clinical history: 28 yo female with an atypical pigmented ... 9.pdfsite by gp •specimen discarded...
TRANSCRIPT
![Page 1: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/1.jpg)
Case 9
Clinical History:
• 28 yo female with an atypical pigmented lesion on the back.
![Page 2: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/2.jpg)
![Page 3: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/3.jpg)
![Page 4: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/4.jpg)
![Page 5: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/5.jpg)
![Page 6: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/6.jpg)
![Page 7: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/7.jpg)
![Page 8: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/8.jpg)
![Page 9: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/9.jpg)
![Page 10: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/10.jpg)
![Page 11: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/11.jpg)
![Page 12: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/12.jpg)
Case 9
Diagnosis:
• A: Superficial spreading melanoma with regression
• B: Melanoma with in invasive spindle cell component
• C: Recurrent naevus
• D: Lentiginous compound dysplastic naevus
• E: Invasive extramammary Paget’s disease
![Page 13: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/13.jpg)
Case 9
Additional Clinical History:
• Histological impression concerning for SSMM
• Additional clinical information at MDM: Previous removal of a pigmented lesion at this site by GP
• Specimen discarded and not sent to Pathology
![Page 14: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/14.jpg)
Case 9
Diagnosis:
• A: Superficial spreading melanoma with regression
• B: Melanoma with in invasive spindle cell component
• C: Recurrent naevus
• D: Lentiginous compound dysplastic naevus
• E: Invasive extramammaryPaget’s disease
![Page 15: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/15.jpg)
Recurrent Naevus -Introduction-
• Repigmentation within a scar due to regrowth of melanocytes following incomplete removal of benign naevus
• Most frequently following shave biopsy of common acquired naevi but also congenital and dysplastic naevi
• Time course: weeks to few months (<6 months)
![Page 16: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/16.jpg)
Recurrent Naevus -Clinical-
• Wide age range
• Most commonly before age 40 years
• F>M
• Predilection for back
![Page 17: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/17.jpg)
![Page 18: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/18.jpg)
![Page 19: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/19.jpg)
![Page 20: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/20.jpg)
![Page 21: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/21.jpg)
![Page 22: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/22.jpg)
![Page 23: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/23.jpg)
![Page 24: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/24.jpg)
![Page 25: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/25.jpg)
![Page 26: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/26.jpg)
![Page 27: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/27.jpg)
![Page 28: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/28.jpg)
![Page 29: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/29.jpg)
![Page 30: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/30.jpg)
Recurrent Naevus -Diagnosis-
• Prior history of trauma/surgery
• Time course
• Review of previous Pathology
![Page 31: Clinical History: 28 yo female with an atypical pigmented ... 9.pdfsite by GP •Specimen discarded and not sent to Pathology . Case 9 Diagnosis: •A: Superficial spreading melanoma](https://reader030.vdocuments.site/reader030/viewer/2022041221/5e0b31f83b5c1853bc7dc884/html5/thumbnails/31.jpg)
Recurrent Naevus -Differential Diagnosis-
Superficial spreading melanoma:
• Reliable separation possible only in the context of appropriate clinical and histological features