circulation: european perspectives in cardiology

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All articles can be accessed from the Circulation Web site (http://circ.ahajournals.org/) by selecting the issue or clicking Browse European Perspectives under CIRCULATION ARCHIVES. European Perspectives in Cardiology European Perspectives in Cardiology Circulation: European Perspectives Circulation : European Perspectives Highlights 2012 A Selection of Memorable and Team 2012 Photographs and Thought-Provoking Research-Related Quotes That Have Appeared in Circulation: European Perspectives in Cardiology in 2012 T he European Perspectives in Cardiology section of Circulation highlights the people, places, associations, initiatives, and ideas behind cardiovascular research and its translation into practice in Europe. Its aim is to provide readers with an opportunity to get to know, understand, and be inspired by each other. In 2012, 339 members of the cardiovascular research community from 26 European countries contributed to the content for the different types of feature, for example, Cardiology in Practice, Centre of Excellence, Funding, Initiatives, Photofeatures, Pioneers, Special Features, Spotlights, and Team 2012. Thank you to all of them for their contributions and for the interesting and memorable photographs they have submitted to illustrate the articles. The index for 2012 is on page f150. An index with links to all features published since 2006 can be accessed on the Circulation Web site ( http://circ.ahajournals.org/ ): click Browse European Perspectives under CIRCULATION ARCHIVES. f145 Circulation December 18/25, 2012 Memorable photographs 2012: Cardio- vascular scientists leading by example. From left to right, Torbjørn Omland, professor of medicine, Centre for Heart Failure Research and KG Jebsen Cardiac Research Centre, head, Campus Akershus University Hospital, Faculty of Medicine, University of Oslo, Oslo, Norway; Stefano Taddei, professor of internal medicine and head, Hyper- tension Unit, Department of Internal Medicine, University of Pisa, Pisa, Italy; Bulent Gorenek, professor of cardiology, Eskisehir Osmangazi University, Cardiology Department, Eskisehir, Turkey (with his daughter); and Frits Prinzen, professor of physi- ology, Department of Physiology, Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, the Netherlands. (July 24 and October 30, 2012) On other pages... Photofeature: A Selection of Team Photographs Published in European Perspectives in 2012 Page f146 INDEX 2012 Complete listing of European Perspectives articles published in Circulation 2012, volumes 125 and 126. Page f150 Thought-Provoking Research-Related Quotes 2012 A selection of quotes about their research provided by members of the cardiovascular research community from 14 European countries who have shared their experiences of and thoughts on cardiovascular research and its translation into practice with readers of European Perspectives in 2012. Page f148 Downloaded from http://ahajournals.org by on January 31, 2022

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All articles can be accessed from the Circulation Web site (http://circ.ahajournals.org/)by selecting the issue or clicking Browse European Perspectives under CIRCulATION ARCHIvES.

European Perspectives in CardiologyEuropean Perspectives in Cardiology

Circulation: European Perspectives

Circulation: European Perspectives Highlights 2012A Selection of Memorable and Team 2012 Photographs andThought-Provoking Research-Related Quotes That Have Appearedin Circulation: European Perspectives in Cardiology in 2012

The European Perspectives in Cardiology section ofCirculation highlights the people, places, associations,initiatives, and ideas behind cardiovascular research and itstranslation into practice in Europe. Its aim is to providereaders with an opportunity to get to know, understand, andbe inspired by each other. In 2012, 339 members of the cardiovascular research

community from 26 European countries contributed to thecontent for the different types of feature, for example,

Cardiology in Practice, Centre of Excellence, Funding,Initiatives, Photofeatures, Pioneers, Special Features,Spotlights, and Team 2012. Thank you to all of them fortheir contributions and for the interesting and memorablephotographs they have submitted to illustrate the articles. The index for 2012 is on page f150. An index with links

to all features published since 2006 can be accessed on theCirculationWeb site (http://circ.ahajournals.org/): click BrowseEuropean Perspectives under CIRCULATION ARCHIVES.

f145Circulation December 18/25, 2012

Memorable photographs 2012: Cardio -vascular scientists leading by example.From left to right, Torbjørn Omland,professor of medicine, Centre for HeartFailure Research and KG JebsenCardiac Research Centre, head, CampusAkershus University Hospital, Facultyof Medicine, University of Oslo, Oslo,Norway; Stefano Taddei, professor ofinternal medicine and head, Hyper -tension Unit, Department of InternalMedicine, University of Pisa, Pisa,Italy; Bulent Gorenek, professor ofcardiology, Eskisehir OsmangaziUniversity, Cardiology Department,Eskisehir, Turkey (with his daughter);and Frits Prinzen, professor of physi-ology, Department of Physiology,Cardiovascular Research InstituteMaastricht, Maastricht University,Maastricht, the Netherlands. (July 24and October 30, 2012)

On other pages...

Photofeature: A Selectionof Team PhotographsPublished in EuropeanPerspectives in 2012

Page f146

INDEX 2012 Complete listing ofEuropean Perspectivesarticles published inCirculation 2012, volumes 125 and 126. Page f150

Thought-Provoking Research-Related Quotes 2012A selection of quotes about their research provided by membersof the cardiovascular research community from 14 Europeancountries who have shared their experiences of and thoughts oncardiovascular research and its translation into practice withreaders of European Perspectives in 2012.Page f148

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Photofeature: A Selection of Team PhotographsPublished in European Perspectives in 2012

Photographs courtesy of Giuseppe Lembo, professor of applied technical and medical science, Department of Molecular Medicine, Sapienza Universityof Rome, Rome, Italy, and chief of the angiocardioneurology clinical and research units, Neuromed Institute, Pozzilli.

January 24: Professor lembo with left, the angiocardioneurology clinical team, and right, the angiocardioneurology researchteam, IRCCS Neuromed, Pozzilli, Italy.

Photograph courtesy of Alma Zernecke, now associate professorin vascular biology, Department of Vascular Surgery, TechnicalUniversity Munich, Munich, Germany.

February 21 and September 4: Professor Zerneckeand her research group, Würzburg, Germany.

Photograph courtesy of Torsten Doenst, chair of the Department ofCardiothoracic Surgery, University Hospital Jena, Friedrich SchillerUniversity of Jena, Jena,

February 21: Professor Doenst and his research group,Department of Cardiothoracic Surgery, university HospitalJena, Friedrich Schiller university of Jena, Jena, Germany.

February 21: Professor Rassaf and his research group, Department ofCardiology, Pulmonary Diseases and vascular Medicine, universityHospital Düsseldorf, Düsseldorf, Germany.

Photograph courtesy of Sonja Schrepfer, Heisenberg professor, UniversityHeart Centre Hamburg, Hamburg, Germany, and director, Transplant andStem Cell Immunobiology Lab, Hamburg.

February 21: Professor Schrepfer and her colleagues at theTransplant and Stem Cell Immunobiology lab, Hamburg,Germany.

March 13: Research Group, Arrhythmia Section, Thorax Insti -tute, Hospital Clinic, university of Barcelona, Barcelona, Spain.

Photograph courtesy of Lluís Mont, associate professor of medicine andhead of the Arrhythmia Section, Thorax Institute, Hospital Clinic,University of Barcelona, Barcelona.

Photograph courtesy of Vera Regitz–Zagrosek, founder and director of theInstitute of Gender in Medicine, Charité University Medical School, Berlin.

February 28: Professor Regitz–Zagrosek and her researchteam at the Institute of Gender in Medicine, Charitéuniversity Medical School, Berlin, Germany.

Photograph courtesy of Cédric Blanpain, Welbio Investigator, Interdisci -plinary Research Institute, Universtité Libre de Bruxelles, Brussels.

April 10: Dr Blanpain and his group, Interdisciplinary ResearchInstitute, universtité libre de Bruxelles, Brussels, Belgium.

Photograph courtesy of Tienush Rassaf, professor of internal medicine/cardiology andattending physician, Department of Cardiology, Pulmonary Diseases and VascularMedicine, University Hospital Düsseldorf, Düsseldorf.

Photograph courtesy of Stefan Frantz, deputy director, Department ofInternal Medicine I, University Hospital Würzburg, Würzburg, and scientific director, Comprehensive Heart Failure Centre, Würzburg.

July 17: Professor Frantz and his lab team, Department of InternalMedicine I, university Hospital Würzburg, Würzburg, Germany.

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Photograph courtesy of Stéphane Germain,director of research, Institut National de la Santéet de la Recherche Médicale, and group leader,Centre for Interdisciplinary Research, Collège deFrance, Paris.

April 17: Dr Germain and lab colleagues,Centre for Interdisciplinary Research,Collège de France, Paris, France.

Photograph courtesy of Michael D. Schneider, head of CardiovascularScience, National Heart and Lung Institute, British Heart Foundation SimonMarks Chair of Regenerative Cardiology, and director, British HeartFoundation Centre of Research Excellence, Imperial College London, London.

April 24: Professor Schneider and his group, National Heartand lung Institute, Imperial College london, london,England.

Photograph courtesy of Arthur Wilde, professorof cardiology and head, Department of Clinicaland Experimental Cardiology, University ofAmsterdam, Amsterdam.

March 27: Department of Clinical andExperimental Cardiology, university ofAmsterdam, Amsterdam, the Netherlands.

Photograph courtesy of Manuel Mayr, professorof cardiovascular proteomics, British Heart Foun -dation Centre of Research Excellence, JamesBlack Centre, King’s College London, London.

May 15: Professor Mayr and his researchgroup, James Black Centre, King’sCollege london, london, England.

Photograph courtesy of Andrew Baker, British Heart FoundationProfessor of Translational Cardiovascular Sciences, British HeartFoundation Cardiovascular Research Centre, Institute of Cardiovascularand Medical Sciences, University of Glasgow, Glasgow.

May 29: Professor Baker and his research group, Institute ofCardiovascular and Medical Sciences, university of Glasgow,Glasgow, Scotland.

Photograph courtesy of Johannes Waltenberger, professor and chair, Internal Medicine,Cardiology and Vascular Medicine, director, Division of Cardiology, managing director,Department of Cardiovascular Medicine, University Hospital Münster, University ofMünster, Münster.

July 31: Professor Waltenberger with his basic, clinical, and translationalmolecular biology lab team, Department of Cardiovascular Medicine,university Hospital Münster, university of Münster, Münster, Germany.

Photograph courtesy of Dorian O. Haskard, British HeartFoundation Sir John McMichael Professor of CardiovascularMedicine, Imperial College London, London.

September 11: Professor Haskard with members ofthe vascular Science Section, Imperial Centre forTranslational and Experimental Medicine,Hammersmith Hospital, london, England.

Photograph courtesy of Helmut Baumgartner, professor of cardiology/adult congenitalheart disease and director, Division of Adult Congenital and Valvular Heart Disease,Department of Cardiovascular Medicine, University of Münster, Münster, Germany.

September 30: Professor Baumgartner with his team at the Division ofAdult Congenital and valvular Heart Disease, Department ofCardiovascular Medicine, university of Münster, Münster, Germany.

Photograph courtesy of Jon Gibbins, director, Institute forCardiovascular and Metabolic Research, School ofBiological Sciences, University of Reading, Reading.

September 25: Professor Gibbins with hisresearch group, Institute for Cardiovascular andMetabolic Research, School of Biological Sciences,university of Reading, Reading, England.

left: November 13: Professor Ruskoaho and hisresearch group, Department of Pharmacologyand Toxicology, Institute of Biomedicine,university of Oulu, Oulu, Finland.Photograph courtesy of Heikki Ruskoaho, professor ofmolecular pharmacology, and head, Department ofPharmacology and Toxicology, Institute of Biomedicine,University of Oulu, Oulu.

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In 2012, 339 members of the cardiovascular research community from 26 European countriesshared their experiences of and thoughts on cardiovascular research and its translation into clinicalpractice with readers of European Perspectives. Here is a selection of thought-provoking quotesabout their research findings. To access the complete articles, see p. f150.

Thought-Provoking Research-Related Quotes 2012

England: Andrew Steptoe, DPhil, DSc, FMedSci, director, Institute ofEpidemiology and Health Care, and BHF Professor of Psychology,Department of Epidemiology and Public Health, university Collegelondon, london “Our mechanistic experimental studies have demonstratedthat stress and other factors stimulate acute cardiovascular, inflammatory,and haemostatic responses relevant to the development of atherosclerosis.4”4. Lewthwaite J, Owen N, Coates A, Henderson B, Steptoe A. Circulating human heat shock protein 60 in the plasmaof British civil servants: relationship to physiological and psychosocial stress. Circulation. 2002;106:196–201.

The Netherlands: Christine Mummery, BSc, PhD, professor of develop-mental biology and head, Department of Anatomy and Embryology,leiden university Medical Centre, leiden “We demonstrated for the firsttime that a complex cardiac phenotype, loss and gain of function Na channelmutation, can be modelled in patient-derived induced pluripotent stem cells.2”2. Davis RP, Casini S, van den Berg CW, Hoekstra M, Remme CA, Dambrot C, Salvatori D, Oostwaard DW,Wilde AA, Bezzina CR, Verkerk AO, Freund C, Mummery CL. Cardiomyocytes derived from pluripotentstem cells recapitulate electrophysiological characteristics of an overlap syndrome of cardiac sodium chan-nel disease. Circulation. 2012;125:3079–3091.

Belgium: Walter J. Paulus, MD, PhD, associate director, CardiovascularCenter, Aalst, Belgium, professor of cardiac pathophysiology, vu universityMedical Center, Amsterdam, the Netherlands “Titin covers the completesarcomere in cardiac muscle. We have been the first to show that in diastolicheart failure a lack of titin phosphorylation renders the cardiomyocytes stiff.5”5. Borbély A, Falcao–Pires I, van Heerebeek L, Hamdani N, Edes I, Gavina C, Leite–Moreira AF, BronzwaerJG, Papp Z, van der Velden J, Stienen GJ, Paulus WJ. Hypophosphorylation of the stiff N2B titin isoformraises cardiomyocyte resting tension in failing human myocardium. Circ Res. 2009;104:780–786.

Spain: Antonio Berruezo, MD, PhD, senior specialist, Arrhythmia Section, ThoraxInstitute, Hospital Clinic, university of Barcelona, Barcelona “We have found that scarcharacterisation by means of high-resolution contrast-enhanced cardiac magnetic resonanceresembles that of electroanatomical voltage maps and can be integrated into the navigationsystem to guide and facilitate ventricular tachycardia ablation.6”6. Andreu D, Berruezo A, Ortiz-Pérez JT, Silva E, Mont L, Borràs R, de Caralt TM, Perea RJ, Fernández-Armenta J, Zeljko H,Brugada J. Integration of 3D electroanatomic maps and magnetic resonance scar characterization into the navigation system toguide ventricular tachycardia ablation. Circ Arrhythm Electrophysiol. 2011;4:674–683.

Switzerland: Christian Templin, MD, attending physician, interventional cardiology and acute cardiac care, Andreas-Grüntzig-Catheterisation laboratories, Department of Cardiology, universityHospital of Zurich, Zurich, Switzerland “We transplanted, for the first time, induced pluripotent stemcells into a preclinical large animal model of myocardial infarction and demonstrated long-term engraftment.7”7. Templin C, Zweigerdt R, Schwanke K, Olmer R, Ghadri JR, Emmert MY, Müller E, Küest SM, Cohrs S, Schibli R, Kronen P, Hilbe M, Reinisch A,Strunk D, Haverich A, Hoerstrup S, Lüscher TF, Kaufmann PA, Landmesser U, Martin U. Transplantation and tracking of human-induced pluripotentstem cells in a pig model of myocardial infarction: assessment of cell survival, engraftment, and distribution by hybrid single photon emission computedtomography/computed tomography of sodium iodide symporter transgene expression. Circulation. 2012;126: 430–439.

Scotland: David Newby, BM, DM, PhD, DSc, FMedSci, BHF John WheatleyChair of Cardiology, director, research and development, NHS lothian,director, Wellcome Trust Clinical Research Facility, director, ClinicalResearch Imaging Centre, interventional cardiologist, Edinburgh RoyalInfirmary, university of Edinburgh, Edinburgh “We found that people whosmoke cigarettes release less of this clot-dissolving protein than nonsmokers.3”3. Newby DE, McLeod AL, Uren NG, Flint L, Ludlam CA, Webb DJ, Fox KAA, Boon NA. Impaired coronarytissue plasminogen activator release is associated with coronary atherosclerosis and cigarette smoking: directlink between endothelial dysfunction and atherothrombosis. Circulation. 2001;103:1936–1941.

Denmark: Erik Berg Schmidt, MD, DMSc, professor of cardiology, Department of Cardiology,Centre for Cardiovascular Research, Aalborg Hospital, Aarhus university Hospital, Aalborg,Denmark “We showed that marine omega-3 polyunsaturated fatty acids may protect against acute coronary syndrome in men.1”1. Joensen AM, Overvad K, Dethlefsen C, Johnsen SP, Tjønneland A, Rasmussen LH, Schmidt EB. Marine n–3 polyunsaturated fattyacids in adipose tissue and the risk of acute coronary syndrome. Circulation. 2011;124:1232–1238.

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Germany: vera Regitz-Zagrosek, MD, PhD, professor of cardiovascular diseases in women, and director, Institute ofGender in Medicine, Charité university Medical School, Berlin“Oestrogen decreases myocyte contractility in male but not femalecardiac myocytes by a novel mechanism.11” 11. Kararigas G, Bito V, Tinel H, Becher E, Baczko I, Knosalla C, Albrecht B, Sipido KR, Regitz-Zagrosek V. Transcriptome characterization of estrogen-treated human myocardium identifiesMYLIP as a sex-specific element influencing contractile function. J Am Coll Cardiol. 2012;59:410–417.

Norway: Imre Janszky, MD, PhD, researcher, Department of Public Health, Faculty of Medicine,Norwegian university of Science and Technology, Trondheim, Norway, and associate professor in epidemiology, Department of Public Health Sciences, Karolinska Institute, Stockholm,Sweden “We demonstrated a dose-dependent association between the number of insomnia symptoms and therisk of acute myocardial infarction.8”8. Laugsand LE, Vatten LJ, Platou C, Janszky I. Insomnia and the risk of acute myocardial infarction: a population study. Circulation. 2011;124:2073–2081.

Headshot photo courtesy of Hanne Strypet

Sweden: Jan Sundquist, MD, PhD, professor of family medicine, lund university,lund, director, Centre for Primary Health Care Research, lund university/RegionSkåne, Malmö, consulting professor, Stanford Prevention Research Center, StanfordSchool of Medicine, Stanford university, Stanford, CA, and family physician,Sorgenfri Primary Health Care Centre, Malmö “Depression is a significant predictor ofcoronary heart disease and the association is strongest in the youngest age groups.9”9. Sundquist J, Li X, Johansson S-E, Sundquist K. Depression as a predictor of hospitalization due to coronary heart disease. Am J

Preventive Med. 2005;29:428–433.

Italy: Massimiliano Gnecchi, MD, PhD, assistant professor in cardiology, university of Pavia, Pavia,Italy, head, lab of Experimental Cardiology for Cell and Molecular Therapy, and attending physician, Intensive Coronary Care unit, Fondazione IRCCS Policlinico San Matteo, Pavia “Wewere the first to show that mesenchymal stem cells repair infarcted hearts more through paracrine mechanismsrather than direct regeneration.14” 14. Gnecchi M, He H, Liang OD, Melo LG, Morello F, Mu H, Noiseux N, Zhang L, Pratt RE, Ingwall JS, Dzau VJ. Paracrine action accounts for markedprotection of ischemic heart by Akt–modified mesenchymal stem cells. Nat Med. 2005;11:367–368.

Slovenia: Pavel Poredoš, MD, PhD, full professor of internal medicine, Medical Faculty,ljubljana, and chief consultant and adviser of vascular medicine, Department for vascularDisease, university Medical Centre of ljubljana “Inflammation is probably a basic mechanism inthe development of deep venous thrombosis and causes endothelial dysfunction and stimulatesthrombogenesis.13”13. Poredos P, Jezovnik MK. In patients with idiopathic venous thrombosis, interleukin-10 is decreased and related toendothelial dysfunction. Heart Vessels. 2011;26:596–602.

Finland: Marja-Riitta Taskinen, MD, PhD, professor of medicine, Helsinki university Hospital, Biomedicum Helsinki,Helsinki, Finland “We found that incretin-based therapies improvepostprandial lipaemia in people with diabetes mellitus.10”10. Eliasson B, Möller-Goede D, Eeg-Olofsson K, Wilson C, Cederholm J, Fleck P, Diamant M,Taskinen MR, Smith U. Lowering of postprandial lipids in individuals with type 2 diabetes treatedwith alogliptin and/or pioglitazone: a randomised double-blind placebo-controlled study.Diabetologia. 2012;55:915–925.

Israel: Joseph Itskovitz-Eldor, MD, DSc, head, Sohnis andForman Families Stem Cell Centre of the Rappaport Faculty ofMedicine, Technion–Israel Institute of Technology, Haifa, anddirector, Department of Obstetrics and Gynecology, RambamHealth Care Campus, Haifa “Derivation of vasculogenic andmultipotent pericytes from human pluripotent stem cells can be usedto develop vasculogenic models for basic research and drug screeningand can contribute to angiogenic regenerative medicine.12”12. Dar A, Domev H, Ben-Yosef O, Tzukerman M, Zeevi-Levin N, Novak A, Germanguz I,Amit M, Itskovitz-Eldor J. Multipotent vasculogenic pericytes from human pluripotentstem cells promote recovery of murine ischemic limb. Circulation. 2012;125:87–99.

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INDEX 2012: European Perspectives Articles Published in Circulation 2012, Volumes 125 and 126

AwardsFinnish Foundation for Cardiovascular Research Grand Prize, Marja–Riitta

Taskinen, MD, PhD, Helsinki, Finland; Markku Laakso, MD, PhD, Kuopio,Finland; Yrjo Antero Kesaniemi, MD, PhD, Oulu, Finland. November6;126:f109–111.

Finnish Foundation for Cardiovascular Research Soisalo Award, TuomoNieminen, MD, PhD, Helsinki, Finland; Markus Juonala, MD, PhD, Turku,Finland; Tuomas Rissanen, MD, PhD, Joensuu, Finland. November6;126:f111–112.

Cardiology in Practice in Europe 2012Guidelines. July 10;126:f7–f12.

Centres of ExcellenceImperial College of Science, Technology, and Medicine, London, England, Kim Fox,

MD, FRCP, FESC, London, England; Michael Schneider, MD, FMedSci, London,England. June 19;125:f139–f144.

Institute of Gender in Medicine, Charite University Medical School, Berlin,Germany, Vera Regitz–Zagrosek, MD, PhD, Berlin, Germany. February28;125:f47–f48.

James Black Centre, King's College London, London, England, Manuel Mayr, MD,PhD, London, England. May 15;125:f112–f113.

FundingATIP–AVENIR Programme, Richard Redon, PhD, Nantes, France; Guillaume

Dumenil, PhD, Paris, France. March 13;125:f59–f60.Bilateral Agence Nationale de la Recherche and Bundesministerium fur Bildung

und Forschung Genomics and Pathophysiology of Cardiovascular andMetabolic Diseases Programme. February 7;125:f28–f30.

British Heart Foundation Intermediate Basic Science Research Fellowships 1,Ariane Chapgier, PhD, London, England; Rebecca R Foster, PhD, Bristol, England;Emma Chung, PhD, MPhys, Leicester, England. May 1;125:f100–f102.

British Heart Foundation Intermediate Basic Science Research Fellowships 2,Nicola J. Mutch, BSc, PhD, Aberdeen, Scotland. June 12;125:f133–f134.

British Heart Foundation Intermediate Basic Science Research Fellowships 3,Richard D. Starke, BSc (Hons), PhD, London, England. June 12;125:f135–f136.

British Heart Foundation Intermediate Basic Science Research Fellowships 4, TomMcKinnon, BSc, PhD, London, England; Emma C. Hart, PhD, Bristol, England.October 23;126:f101–f102.

British Heart Foundation Professorships. April 3;125:f73–f78.Caja Madrid Foundation Fellowships. April 17;125:f88–f90.Deutscher Akademischer Austauschdienst Programme des Projektbezogenen

Personenaustauschs DAADppp Mobility Programme Germany—Norway, MartinBurger, PhD, Münster, Germany; Bjorn Fredrik Nielsen, PhD, Aas, Norway. May8;125:f107–f108.

Dr Saal van Zwanenberg Foundation. January 24;125:f13–f15.European Molecular Biology Organisation Awards, Carola Rintisch, PhD,

Berlin–Buch, Germany; Sonia Stefanovic, PhD, Amsterdam, the Netherlands;Jaakko L. O. Pohjoismaki, PhD, Bad Nauheim, Germany; Cedric Blanpain, MD,PhD, FNRS, Brussels, Belgium; Holger Gerhardt, PhD, Leuven, Belgium; Ralf H.Adams, PhD, Munster, Germany. April 10;125:f79–f83.

European Research Council Grants. January 17;125:f7–f9.Finnish Cultural Foundation Central Fund. June 5;125:f129–f132.Finnish Foundation for Cardiovascular Research Scholarships 2012—1, Heikki

Ruskoaho, MD, PhD, Oulu, Finland. November 13;126:f119–f120.Finnish Foundation for Cardiovascular Research Scholarships 2012—2, Heikki V.

Huikuri, MD, Oulu, Finland; Tiina Maria Helio, MD, PhD, Helsinki, Finland.November 20;126:f125–f126.

Fondazione "Per il Tuo Cuore" (Heart Care Foundation) Scholarships, MarcoMagnoni, MD, Florence, Italy; Margherita Calcagnino, MD, Florence, Italy; EnricoAmmirati, MD, Milan, Italy; Bruno Merlanti, MD, Florence, Italy. November27;126:f130–f132.

Friedrich Naumann Foundation Scholarships, Roland Klingenberg, MD, Zurich,Switzerland. April 24;125:f96.

Fritz Thyssen Stiftung. July 31;126:f29–f30.Fundatia Dinu Patriciu Open Horizons Scholarship, Razvan Ionasec, PhD, Leipzig,

Germany. July 17;126:f17.Heisenberg Programme, Lars S. Maier, MD, Gottingen, Germany; Alma Zernecke,

MD, Würzburg, Germany; Tienush Rassaf, MD, Dusseldorf, Germany; TorstenDoenst, MD, Jena, Germany; Sonja Schrepfer, MD, PhD, Hamburg, Germany.February 21;125:f37–f42.

Human Frontier Science Program. May 22;125:f118–f120.Hungarian State Scholarships, Arnold Sipos, MD, PhD, Budapest, Hungary;

Zsuzsanna Takaes–Szabo, MD, Miskolc, Hungary. May 29;125:f124.Klaus Murmann Fellowship Programme, Christina Brammen, Gottingen, Germany;

Romina Maria Rosch, Cologne, Germany; Sarina Schafer, Mainz, Germany. July24;126:f23–f24.

L'Oreal–United Nations Educational, Scientific, and Cultural Organisation forWomen in Science Awards, Elza D. van Deel, PhD, Rotterdam, the Netherlandsand London, England. October 16;126:f95–f96.

Margarete von Wrangell Habilitation Programme, Katja E. Odening, MD, Freiburg,Germany. May 29;125:f125–f126.

Marie–Curie Intra–European Fellowship for Career Development 1, Ana BelenCerezo Lopez, PhD, Norwich, England. January 3/10;125:f6.

Marie–Curie Intra–European Fellowship for Career Development 2, AndreasSigfridsson, PhD, Zurich, Switzerland. March 6;125:f54.

Marie–Curie Intra–European and Outgoing International Fellowships. February14;125:f35–f36.

Marie Curie Outgoing International Fellowship, Philip L S M Gordts, PhD, Leuven,Belgium. June 12;125:f136–f137.

Portuguese Foundation for Science and Technology. August 28;126:f49–f54.Research Foundation Flanders. September 25;126:f77–f78.Saatioiden Postdoc Pooli (The Foundations’ Postdoc Pool), Johanna Lahteenvuo,

MD, PhD, Kuopio, Finland; Hanna P. Lesch, PhD, Kuopio, Finland. June5;125:f127–f129.

Societa Italiana di Cardiologia Scholarships. October 2;126:f79–f84.Slovenian Research Agency, Veronika Kralj–Iglic, PhD, Ljubljana, Slovenia; Mojca

Stegnar, PhD, Ljubljana, Slovenia; Pavel Poredos, MD, PhD, Ljubljana, Slovenia;Marko Noc, MD, PhD, Ljubljana, Slovenia; Breda Pecovnik Balon, MD, PhD,Maribor, Slovenia; Igor Krizaj, PhD, Ljubljana, Slovenia. July 3;126;f1–f6.

Spanish Society of Cardiology Research Grants, Vicente Bodi, MD, PhD, Valencia,Spain, David Garcia–Dorado, MD, PhD, Barcelona, Spain; Marisa G.Crespo–Leiro, MD, PhD, La Coruna, Spain; Antonio Berruezo, MD, PhD,Barcelona, Spain. October 16;126:f91–f95.

Swiss Society of Cardiology Cardiovascular Biology Prize 2009 and 2010, GabrielaKania, PhD, Zurich, Switzerland; Elena Osto, MD, PhD, Zurich, Switzerland.November 6;126:f113–f114.

Swiss Society of Cardiology Prize 2011, Christian Templin, MD, Zurich, Switzerland.October 30;126:f107–f108.

YGGDRASIL Programme, Mihai Bogdan Preda, PhD, Bucharest, Romania. March27;125:f72.

InitiativesCardiology and Development, Xavier Jouven, MD, PhD, Paris, France. March

6;125:f52–f53.Safe and Sustainable Review of Paediatric Cardiac Services in England and Wales.

October 9;126:f85–f89.Setting Up a Basic Science Lab to Investigate Stem Cell Therapy in Italy,

Massimiliano Gnecchi, MD, PhD, Pavia, Italy. December 11;126:f143–f144.Stent for Life Initiative, Steen Dalby Kristensen, MD, DMSc, Skejby, Denmark.

February 7;125:f25–f27.

PioneersBaumgartner, Helmut, MD, Münster, Germany. November 20;126:f121–f124.Haskard, Dorian O., DM, FRCP, FMedSci. London, England. September

11;126:f61–f66.Itskovitz–Eldor, Joseph, MD, DSc, Haifa, Israel. March 20;125:f61–f65.Just, Hanjoerg, MD, FRCP, Freiburg, Germany. February 14;125:f31–f34.Moorman, Antoon F. M., PhD, Amsterdam, the Netherlands. August 21;126:f43–f48.Mummery, Christine, BSc, PhD, Leiden, the Netherlands. September 18;126:f67–f71.Regitz–Zagrosek, Vera, MD, PhD, Berlin, Germany. February 28;125:f43–f46.Santinelli, Vincenzo, MD, Cotignola, Italy. May 8;125:f103–f106.Schneider, Michael D., MD, FMedSci, London, England. April 24;125:f91–f96.Steptoe, Andrew, MA, DPhil, DSc, FMedSci, London, England. November

13;126:f115–f118.Waltenberger, Johannes, MD, Münster, Germany. July 31;126:f25–f28.Wilde, Arthur, MD, PhD, Amsterdam, the Netherlands. March 27;125:f67–f70.Yla–Herttuala, Seppo, MD, PhD, Kuopio, Finland. December 11;126:f139–f142.

Special FeaturesA Day in the Life of a Young Investigator. June 26;125:f145–150.A Day in the Life of a Young Investigator, Minna Unelma Kaikkonen, PhD, Kuopio,

Finland. July 17;126:f18.American Heart Association Scientific Sessions 2012, Los Angeles, CA, November

3 to 7. December 4;126:f133–f138.History of the German Cardiac Society, Gunther Arnold, MD, PhD, Dusseldorf,

Germany. January 4/11;123:f1–f6.Sports and Exercise for Cardiovascular Health. July 24;126:f19–f22.Who’s Who in Cardiology: Chairs of Cardiology in Germany. August 7;126:f31–f36.

SpotlightsBaker, Andrew, PhD, Glasgow, Scotland. May 29;125:f121–f123.Barrere–Lemaire, Stephanie, PhD, Montpellier, France. January 31;125:f19–f21.Dar, Ayelet, MSc, PhD, Haifa, Israel. March 20;125:f62.Frantz, Stefan, MD, Würzburg, Germany. July 17;126:f13–f16.Germain, Stephane, BSc, PhD, Paris, France. April 17;125:f85–f87.Gibbins, Jonathan, PhD, Reading, England. September 25;126:f73–f76.Janszky, Imre, MD, PhD, Stockholm, Sweden and Trondheim, Norway. January

17;125:f10–f11.Kivimaki, Mika, PhD, London, England. October 23;126:f97–f100.Lembo, Giuseppe, MD, PhD, Rome, Italy and Pozzilli, Italy. January 24;125:f16–f18.Madeddu, Paolo, MD, Bristol, England. August 14:126:f37–f39.Mayr, Manuel, MD, PhD, London, England. May 15;125:f109–f111.Mont, Lluis, MD, PhD, Barcelona, Spain. March 13;125:f55–f58.Newby, David, BA, BSc, PhD, BM, DM, DSc, FMedSci, Edinburgh, Scotland. September

4;126:f55–f57.Paulus, Walter J., MD, PhD, Amsterdam, the Netherlands. January 3/10;125:f1–f3.Prasad, Sanjay, MD, FRCP, London, England. January 3/10;125:f4–f5.Prinzen, Frits, PhD, Maastricht, the Netherlands. October 30;126:f103–f106.Purnode, Philippe, MD, Brussels, Belgium. May 22;125:f115–f117.Rodondi, Nicolas, MD, MAS, Bern, Switzerland. November 27;126:f127–f129.Schmidt, Erik Berg, MD, DMSc, Aalborg, Denmark. March 6;125:f49–f51.Sundquist, Jan, MD, PHD, Lund and Malmo, Sweden. August 14;126:f37–f42.Sydow, Karsten, MD, Hamburg, Germany. May 1;125:f97–f99.Zernecke, Alma, MD, Munich, Germany. September 4;126:f58–f60.

Young Investigator SpotlightsWolf, Dennis, MD, Freiburg, Germany, January 31;125:f22–f23.

All articles can be accessed through the Circulation web site(http://circ.ahajournals.org/) by selecting the issue or clicking“Browse European Perspectives” under CIRCULATION ARCHIVES

Editor: Christoph Bode, MD, FESC, FACC, FAHAManaging Editor: Lindy van den Berghe, BMedSci, BM, BSWe welcome comments. E–mail: [email protected]

The opinions expressed in Circulation: EuropeanPerspectives in Cardiology are not necessarily those of theeditors or of the American Heart Association.

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