Chronic myelogenous leukemia

A 65-year-old male give chief complaint

of feeling tired for 2 years.

The physician noticed found the spleen

enlarged and others were negative.

RBC: 3.0×1012/L Hb:86 g/L

WBC: 145×109/L

DC: Immature cells 60% ; Bands 15% ;

Seg. 13%; B 6%; E 5% ; M 1 %

PLT: 400×1012/L

Laboratory findings:

Blood smear

Bone Marrow

Bone Marrow

Ph chromosome

1. According to the case and BM, what is the most

probable diagnosis?

2. What are the diagnostic bases?

3. What additional tests are needed to establish

the diagnosis?

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