cheminform abstract: taxane diterpenes. part 3. formation of the eight-membered b-ring by...

1997 terpenes terpenes U 0200 10 - 157 Taxane Diterpenes. Part 3. Formation of the Eight-Membered B- Ring by Semi-Pinacol Rearrangement. — The solvolytic semi-pinacol type rearrangement of 10β-( triﬂuoromethylsulfonyl)oxymethyl substituted bicyclo(5.4.0)undecenone derivatives such as (I) and (IV) as well as some 10β- formyl derivatives is found to be a very high yielding and regiospeciﬁc method for construction of the eight-membered B-ring of taxanes. — (MAGNUS, P.; DIORAZIO, L.; DONOHOE, T. J.; GILES, M.; PYE, P.; TARRANT, J.; THOM, S.; Tetrahedron 52 (1996) 45, 14147-14176; Dep. Chem. Biochem, Univ. Tex., Austin, TX 78712, USA; EN) 1

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Page 1: ChemInform Abstract: Taxane Diterpenes. Part 3. Formation of the Eight-Membered B-Ring by Semi-Pinacol Rearrangement

1997 terpenes

terpenesU 0200

10 - 157Taxane Diterpenes. Part 3. Formation of the Eight-Membered B-Ring by Semi-Pinacol Rearrangement. — The solvolytic semi-pinacoltype rearrangement of 10β-( trifluoromethylsulfonyl)oxymethyl substitutedbicyclo(5.4.0)undecenone derivatives such as (I) and (IV) as well as some 10β-formyl derivatives is found to be a very high yielding and regiospecific methodfor construction of the eight-membered B-ring of taxanes. — (MAGNUS,P.; DIORAZIO, L.; DONOHOE, T. J.; GILES, M.; PYE, P.; TARRANT, J.;THOM, S.; Tetrahedron 52 (1996) 45, 14147-14176; Dep. Chem. Biochem,Univ. Tex., Austin, TX 78712, USA; EN)

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