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2000 pyrimidine derivatives pyrimidine derivatives R 0510 30 - 132 Suitably Functionalized Pyrimidines as Potential Antimycotic Agents. — Fourteen pyrimidines of type (IV), (VIII), and (X) are prepared (no yields given) and tested for their antifungal activities. (IVb) is the most potent compound. The chloro-atom in the 4-position of the pyrimidine is essential for the activity. — (AGARWAL, NIDHI; RAGHUWANSHI, SANDEEP K.; UPADHYAY, D. N.; SHUKLA, P. K.; RAM, VISHNU J.; Bioorg. Med. Chem. Lett. 10 (2000) 8, 703-706; Div. Med. Chem., Cent. Drug Res. Inst., Lucknow 226 001, India; EN) 1

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Page 1: ChemInform Abstract: Suitably Functionalized Pyrimidines as Potential Antimycotic Agents

2000 pyrimidine derivatives

pyrimidine derivativesR 0510

30 - 132Suitably Functionalized Pyrimidines as Potential Antimycotic Agents.— Fourteen pyrimidines of type (IV), (VIII), and (X) are prepared (no yieldsgiven) and tested for their antifungal activities. (IVb) is the most potentcompound. The chloro-atom in the 4-position of the pyrimidine is essentialfor the activity. — (AGARWAL, NIDHI; RAGHUWANSHI, SANDEEP K.;UPADHYAY, D. N.; SHUKLA, P. K.; RAM, VISHNU J.; Bioorg. Med. Chem.Lett. 10 (2000) 8, 703-706; Div. Med. Chem., Cent. Drug Res. Inst., Lucknow226 001, India; EN)

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