cheminform abstract: structure—activity relationship in two series of aminoalkyl substituted...
TRANSCRIPT
2000 antibiotics
antibioticsU 1200
07 - 210Structure–Activity Relationship in Two Series of Aminoalkyl Substi-tuted Coumarin Inhibitors of Gyrase B. — Various novel novobiocin-liketitle compounds are synthesized and tested for their antibacterial activity. Es-pecially derivative (X) shows a uniformly broad antibacterial spectrum. —(LAURIN, PATRICK; FERROUD, DIDIER; SCHIO, LAURENT; KLICH,MICHAEL; DUPUIS-HAMELIN, CLAUDINE; MAUVAIS, PASCALE; LAS-SAIGNE, PATRICE; BONNEFOY, ALAIN; MUSICKI, BRANISLAV; Bioorg.Med. Chem. Lett. 9 (1999) 19, 2875-2880; Dep. Med. Chem., Res. Cent.,Hoechst Marion Roussel, F-93230 Romainville, Fr.; EN)
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