cheminform abstract: stereoselective synthesis of precursors of the macrolide antibiotics via...

1999 antibiotics antibiotics U 1200 19 - 262 Stereoselective Synthesis of Precursors of the Macrolide Antibiotics via Reactions of Sulfur Ylides with Chiral Aldehydes. — Building block (IX), potentially useful for the synthesis of macrolide natural products, is prepared by a route involving the reaction of chiral aldehyde (VI) with the stabi- lized sulfur ylide (VII) providing the epoxide (VIII). — (LOPEZ-HERRERA, F. JORGE; SARABIA-GARCIA, FRANCISCO; PEDRAZA-CEBRIAN, GRA- CIA MARIA; PINO-GONZALEZ, MARIA SOLEDAD; Tetrahedron Lett. 40 (1999) 7, 1379-1380; Dep. Bioquim., Biol. Mol. Quim. Org., Fac. Cienc., Univ. Malaga, E-29071 Malaga, Spain; EN) 1

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Page 1: ChemInform Abstract: Stereoselective Synthesis of Precursors of the Macrolide Antibiotics via Reactions of Sulfur Ylides with Chiral Aldehydes

1999 antibiotics

antibioticsU 1200

19 - 262Stereoselective Synthesis of Precursors of the Macrolide Antibioticsvia Reactions of Sulfur Ylides with Chiral Aldehydes. — Buildingblock (IX), potentially useful for the synthesis of macrolide natural products, isprepared by a route involving the reaction of chiral aldehyde (VI) with the stabi-lized sulfur ylide (VII) providing the epoxide (VIII). — (LOPEZ-HERRERA,F. JORGE; SARABIA-GARCIA, FRANCISCO; PEDRAZA-CEBRIAN, GRA-CIA MARIA; PINO-GONZALEZ, MARIA SOLEDAD; Tetrahedron Lett. 40(1999) 7, 1379-1380; Dep. Bioquim., Biol. Mol. Quim. Org., Fac. Cienc., Univ.Malaga, E-29071 Malaga, Spain; EN)

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