2000 pyrazine derivatives

pyrazine derivativesR 0550

48 - 173Polymer-Supported Reagents for Multi-Step Organic Synthesis:Application to the Synthesis of Sildenafil. — A polymer-supportedsynthesis of the known sildenafil (IX) is created with the aim to apply thisstrategy to the synthesis of other important drugs. — (BAXENDALE, IANR.; LEY, STEVEN V.; Bioorg. Med. Chem. Lett. 10 (2000) 17, 1983-1986;Dep. Chem., Univ. Cambridge, Cambridge CB2 1EW, UK; EN)

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