cheminform abstract: a new and efficient asymmetric synthesis of 1-amino-1-alkylphosphonic acids
TRANSCRIPT
2001 organo-phosphorus compounds
organo-phosphorus compoundsS 0080
12 - 167A New and Efficient Asymmetric Synthesis of 1-Amino-1-alkylphosphonic Acids. — A new and efficient method for theasymmetric synthesis of the title aminophosphonic acids [cf. (IX)] involvingthe diastereoselective alkylation of bicyclic chloromethyl phosphonamides(III) or (IV) derived from (S)-anilinomethylpyrrolidine (I) as the key step isaccomplished. — (YUAN, CHENGYE; LI, SHUSEN; WANG, GUOQIANG;Heteroat. Chem. 11 (2000) 7, 528-535; Shanghai Inst. Org. Chem., Chin.Acad. Sci., Shanghai 200032, Peop. Rep. China; EN)
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