chapter 18 - transport system (part 1)
TRANSCRIPT
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TRANSPORT SYSTEM
Powerpoint@lecture Slides Are Prepared By Biology Lecturer, KMPk
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18.1:
MAMMALIAN
HEART AND
ITS REGULATION
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At the end of this topic, students should be able to:
a. explain the initiation of heart beat and its
control.
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Structure of Heart
The internal cavity of the
heart divided into 4
chambers:
Right atrium
Right ventricle
Left atriumLeft ventricle
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Structure of Heart
Right atrium
receives deoxygenated
blood fromsystemic veins
Left atrium
receives oxygenatedblood from the
pulmonary veins
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Structure of Heart
Right ventricles passed
deoxygenated blood
through pulmonary artery
to lung for gases exchange
Left ventricles passed
oxygenated blood through
aorta to all body tissues
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Pulmonary (lung) circuit:
The right ventricle pumps
blood to the lungs viathe pulmonary arteries.
Blood in capillaries loads
O2 and unloads CO2.
Oxygenated blood returnsvia pulmonary veins to
the left atrium and left
ventricle.
Mammalian
cardiovascular system
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Systemic circuit:
Oxygenated blood leaves the
heart via the aortato capillaries in the head and
arms, and also to capillaries in
the abdominal organs and legs.
Oxygen-poorblood returnsvia superiorvena cava
and inferiorvena cava, then
empty into the right atrium.
Mammalian
cardiovascular system
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Path of Blood
Oxygenated blood
Left atrium
Left ventricle
Left ventricle
Body tissues
Systemic
Circulation
Pulmonary
Circulation
Via pulmonary
vein
Through AV valve
Via aorta
Deoxygenated blood
Right atrium
Right ventricle
lungs
Via superior
vena cava
Through AV valve
Via pulmonary
artery
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Initiation of Heart Beat
The cardiac muscle is
myogenic
Contracts and relaxesautomatically
Dont need nerve
stimulation
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Sinoatrial Node (SA)/
pacemaker:
Located at right atrium, near
opening of vena cava
Act as a pacemaker.
Initiates generation of impulse
Atrioventricular Node (AV):
Located in the right atrium
Initiation of Heart Beat
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Spread rapidly through the wall
of atria. Contract unison
Initiation of Heart Beat
1
SA node stimulate heart
contraction on its own
2
Passed to AV node
3
impuls
impuls
Delayed 0.1s
impuls
4
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Spreading to the ventricular walls
towards the heart apex.
- Conduct by bundle of His and
Purkinje fibres
Initiation of Heart Beat
4
Ensures the atria empty
completely
6
Forcing blood into the pulmonary
arteries and aorta
5
impuls
Ventricles contract
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Control of Heart Rate
Action of SAN (pacemaker)
modified according to the
needs of the body
Examples: Action of SAN
increased during physical
activity
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Control of Heart Rate
Heart control centre (in
medulla oblongata)
The sympathetic nervestimulates an increase in
heart rate
The vagus nerve stimulatesa decrease in heart rate
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Control of Heart Rate
In cardiovascular centre,
there two region that
control the heart rate
cardiac inhibitory centre
cardiac acceleratory
centre
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To increase heart beat
Impulse from cardioacceleratory
center (sympathetic)
are sent via
sympathetic cardiac nerves
Released noradrenaline
Increase the rate of impulseproduction by SAN and AVN
Increase heart rate
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To slow down heart beat
Impulse from cardioinhibitorycenter (parasympathetic)
Are sent via parasympathetic
nerve (vagus nerve)
Released acetylcholine
Inhibit the production of impulses
by SAN and AVN
Slow down heart rate
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Initiation ofHeart Beat
1 2
3
56
4
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Question
The heart of a normally developing human fetus
has a hole between the left and the right atria. In
some cases, this hole does not close completely
before birth. If the hole werent surgically corrected,how it would affect the O2 content of blood entering
the systemic circuit?
The O2 content would be abnormally low because
some oxygen-depleted blood returned to the right
atrium from systemic circuit would mix with the
oxygen-rich blood in the left atrium.
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The oxygen content would be abnormally low
because some oxygen-depleted blood returned to
the right atrium from systemic circuit would mix
with the oxygen-rich blood in the left atrium.
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Cardiac cycle.
Factors affecting
heart beat.