chapter 11 introduction to genetics - mr. haring's...
TRANSCRIPT
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Chapter 11 Introduction to Genetics
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11.1 Gregor Mendel
• Genetics is the scientific study of heredity – How traits are passed
from one generation
to the next
• Mendel – Austrian monk (1822)
– Used Pea Plants
(crossed and looked
at Off-spring)
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Pea Plant
• Have both male
(sperm) and female
(eggs) on same flower
– Fertilization –
when sperm and
egg meet
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7 Traits
• True Breeding – when a plant is allowed to self- pollinate and it produces offspring
identical it themselves
Example: Tall plants – Always produce tall offspring.
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Pollination
• Cross – One plant gives the sperm (male) while the other gives the egg (female)
• Self – plant gives both male and female reproductive cells to produce the offspring. • When 2 contrasting traits (purple X white) (P) were
crossed the offspring were called hybrids (F1)
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Generations • P -- purple x white
• F1 (hybrids) – purple (all of them) –This was a surprise to Mendel
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11.2 Crosses and Probability
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Trait
• A specific Characteristic that can vary from person to person
– Example:
• Seed color
• Flower color
• Height
• Eye color
• Ear lobe attachment
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Chemical Factors
• Genes – chemical factors that determine traits
– Alleles – the different forms a gene comes in
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Genes and Alleles
• Gene – the chemical factor (DNA) that determines traits. Genes are a section of DNA that code for one trait. All of your DNA code for all of your traits
– Alleles are the different forms that the Genes can come in.
• Example:
–Gene = Seed color DNA code
–Alleles = Yellow or Green DNA code
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Mendel’s Conclusions 1. Inheritance
determined by genes
(factors) passed from
one generation to the
next
1. Occur in two
Contrasting alleles
(forms)
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Principal of Dominance
• Some alleles dominant (hide) other alleles (recessive)
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Segregation
• The two alleles separate when forming gametes (sperm or egg)
– Process of Meiosis
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Punnet Square
• Probability: The likelihood that an event will occur. It is likely that a flipped coin will come up heads 1 out of 2 times or (50% of the time)
• Predict Possible offspring
• Tall (Tt) X Tall (Tt)
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• Homozygous Same alleles (aa or AA)
• Heterozygous Different alleles(Aa)
• Phenotype
Outward (wrinkled)
• Genotype 2 Allele that make up
gene (aa)
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What is the phenotype, genotype of each parent? (Use color and letters to explain)
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P Generation Cross (true breeders)
Step 1: Separate Alleles Step 2:
Bring Alleles together in each box
True breeder
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F1 generation Cross (self Pollination)
Heterozygous (Aa) X Heterozygous (Aa)
Ratios Genotypic: 1:2:1 Phenotypic: 3:1
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Practice Cross
• TT (Tall) X tt(short) – Do the P generation cross
• Do the F1 generation self pollination
• State the ratios of the F2 generation
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11.3 Exploring Mendelian Genetics
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Independent Assortment
• If two different genes are examined are they linked or do they separate independently during meiosis?
– Mendel’s pea traits Assort Independently
– Parent genotype: RrTt X RRTT
– Gamete Alleles (top/side of punnett square)
• (Top) RT, Rt, rT, rt (Side) RT, RT, RT, RT
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Large Punnett Square (2 gene cross)
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Practice: Set up the following PS
• Heterozygous Tall, heterozygous Round crossed with Homozygous Tall, wrinkled pea plant.
1. Write out Parents (remember 2 genes = 4 alleles)
2. Set up top and side of PS (4 top, 4 side)
1. 2 alleles per box
3. Fill in the boxes (16 boxes)
1. 4 alleles per box
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Beyond Mendel
• Incomplete Dominance: The Heterozygous shows a blending between both traits
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Beyond Mendel
• Co-dominance: Heterozygous show both traits at the same time
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Beyond Mendel
• Multiple Alleles: Having more than 2 alleles in a population. So there is a hierarchy of dominance: Full color > Chinchilla > Himalayan > albino (rabbits)
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Beyond Mendel
• Polygenic Traits: Controlled by two or more genes.
– Skin Color in humans has four different genes
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Meiosis 11.4
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Chromosomes
• Diploid(2N): When you
have both copies of
the chromosome
(1 from Mom and
1 from Dad)
• Haploid(N): When you have one copy of the chromosome (occurs in gametes: sperm or egg)
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Goal of Meiosis
• Take a Diploid cell and make 4 unique haploid gametes
• So that during fertilization (sperm and egg meet) you make one unique diploid individual.
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Haploid/Diploid, Gamete or Organism
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Chromosome
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2 stages of Meiosis
• Meiosis 1 – homologous chromosome separate
• Meiosis 2 – Chromatids separate
– End result = 4 unique cells
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Crossing Over
• During Prophase 1 the homologous chromosomes share “legs” and exchange genes.
– This leads to more variation within a population
– When the Homologous chromosomes are paired up this is called a tetrad
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Crossing Over