chapter 11 cell communication. question? u how do cells communicate?
TRANSCRIPT
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Chapter 11Cell Communication
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Question?
How do cells communicate?
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Why do cells communicate?
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Cell Communication
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Cell Signaling (C.S.)
Is a relatively “new” topic in Biology and AP Biology.
Appears to answer many questions in medicine.
Is a topic you’ll be hearing more about in your future.
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Stages of C.S.
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Reception
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Transduction
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Response
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Reception
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Direct Contact
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Direct Contact
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Signal Molecules
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Signal Molecules
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Receptor Molecules
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Receptor Molecules
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G-protein linked
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G-protein
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G-protein
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G-protein linked receptors
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G-protein linked receptors
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G-protein linked receptors
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Tyrosine-Kinase Receptors
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Mechanism
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Intracellular Proteins
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Tyrosine-Kinase Receptors
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Ion-channel Receptors
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Ion-channel Receptors
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Intracellular Signals
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Intracellular Signals
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Comment
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Signal-Transduction Pathways
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Protein Phosphorylation
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Protein Kinase
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Amplification
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Secondary Messengers
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Secondary Messengers
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cAMP
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Calcium Ions
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Calcium Ions
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Inositol Trisphosphate(IP3)
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Start here Or Start here
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Animation Link
http://entochem.tamu.edu/G-Protein/index.html
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Cellular Responses
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Cytoplasmic Regulation
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Transcription Regulation
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Question
If liver and heart cells both are exposed to ligands, why does one respond and the other not?
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Alternate explanation
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Comment
Chapter focused only on activating signals. There are also inactivation mechanisms to stop signals.
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Summary Don’t get bogged down in
details in this chapter. Use the KISS principle.
Know - 3 stages of cell signaling.
Know - At least one example of a receptor and how it works (in detail).