centrifugal analyzer (clinical chemistry)

7/24/2019 Centrifugal Analyzer (Clinical Chemistry)

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CENTRIFUGAL ANALYZER

Ayson

De Ala

Elica

Marilag

Moral

Group 3MT3C


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CENTRIFUGAL ANALYSIS

-A discrete system where the transfer ofsolutions is carried out by the use ofcentrifugal force.

1967 - Dr. Norman Anderson developed aprototype at the a! "idge National#aboratory

197$ - %irst commercial centrifugalanaly&er was introduced as a spin-o'technology from NA(A


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Principle

)entrifugal forces are applied todiscretely add reagents to samplesand to propel the mi*tures into the

corresponding cuvettes +ses the force generated by

centrifugation to transfer and the

contain li,uids in separate cuvettesfor measurement

(amples and reagents are added in aspecially designed centrifugal type

cuvette that has three main


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A!an"ages

atch Analysis

(imultaneous addition of

reagents to all samples "e,uires small sample

+ses small reagent volumes

)an be programmed to carry outmany di'erent assay methods.


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Disa!an"ages

nly one test type can beperformed each time.

/he test done per batch isonly for a speci0c analyte.

/he ,uality of cuvette anduniformity of detection windowis crucial.


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TEC#NICAL $ARTS

ANA#2/3)A# 4D+#5

/eon transfer disc

)uvette rotor

(tationary photometric spectrophotometricand in some instruments uorometricsystem

(ynchronisation system Device for the control and the

measurement of the reaction temperature

8ashing and drying part


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DETECTI%N UNIT

D5/5)/"

433N: );A45"

(2"3N:5 D"3


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;ow does it wor!>

1. "otor disc is loaded with reagents diluentsand samples in appropriate wells includingthe blan! and control sera.

?. /he rotor starts spinning and the reagents

are transferred outward through thecapillary passages due to the centrifugalforce.

@. /he reaction proceeds in the peripheral

cuvettes and is detected by thephotometer reading each cuvette severaltimes as the disc rotates.

. /he signals generated by each cuvette isread and processed by a computer and the

results are displayed.


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Co&as'(io

/he )obas io B"ocheC is adiscrete spectrometriccentrifugal analyser which iscapable of monitoring ?9

reaction cuvettes. /hedispensing and analysingsystems are contained withinone unit and an 3ntel $$A

microprocessor controls thetotal system.


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C%(AS'MIRA $lus

/he "oche )obas 4ira =lus )) is a benchtop randomaccess analy&er is designed to meet laboratory needs under

virtually any circumstances. /his machine uses the same

advanced technology as the "oche )obas 4ira =lus however

the automated cuvette changer B))C enables lab operators to

load up to @1? cuvettes at a time and let the analy&er run

without intervention.

/his fully programmable analy&er provides trouble-freeoperation random-access testing e*ibility and a broad test

menu including (/A/ capability.

)ey Fea"ures

All consumables available from A( Diagnostics

1$ programmed tests

=hotometric colorimetric optical system

5nd point assay method

Einetic assay method

Direct (ampling capability


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C%(AS'FARA


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"eferencesF

ishop 4. et.al.G )linical )hemistryF=rinciples /echni,ues and)orrelations

centrifugal analyzer (clinical chemistry)

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