CELL PHYSIOLOGY:

1.CELL MEMBRANE IS:

a. more permeable to K+ than Na+ - CORRECT

b. the main site for ATP synthesis

c. composed cheifly of lipids

d. composed of two layers of lipids and proteins

2. CELL MEMBRANE HAS:

a. glycogen molecules embedded in it

b. protein molecules embedded in it - CORRECT

c. structure similar to protein bilayer

d. a thickness of 40mm

3. CELL MEMBRANE COMPOSED OF HIGH PERCENTAGE OF:

a. proteins - CORRECT

b. lipids

c. phospholipids

d. carbohydrates

4. THE MEMBRANE BOUND ORGANELLE OF CELL IS:

a. ribosome

b. filaments

c. microtubles

d. golgi apparatus - CORRECT

5. SECRETORY VESICLES ARE FORMED BY:

a. rough endoplasmic reticulum

b. golgi bodies

c. lysosomes - CORRECT

d. peroxisomes

6. THE ORGANELLE THAT CONTAINS DIGESTIVE ENZYMES IS:

a. mitochondria

b. lysosomes - CORRECT

c. ribosomes

d. golgi apparatus

7. THE ORGANELLE THAT COMBINES PROTEINS WITH CARBOHYDRATES AND PACKAGE THEM WITHIN VESICLES FOR SECRETION IS:

a. golgi complex - CORRECT

b. SER

C. RER

d. ribosomes

8. MITOCHONDRIA ARE PRESENT IN ALL THE CELLS OF THE BODY EXCEPT:

a. hepatocytes

b. cardiac muscle cells

c. mature RBC - CORRECT

d. skeletal muscle cells

9. LYSOSOMES CONTAINS:

a. oxidases

b. hydrolases -CORRECT

c. reductases

d. esterases

10. The source from where the nutrients come in ECF is:

a. brain

b. kidney

c. muscle

d. GIT - CORRECT.

11. MITOCHONDRIAL MATRIX contains all EXCEPT:

a. RNA

b. DNA

c. pigment - CORRECT

d. oxidative enzymes

12. All the statements about functions of smooth endoplasmic reticulum are true EXCEPT:

a. in pituitary, synthesize steroid hormone

b. in liver, causes detoxification

c. in nerve cell, forms axon and dendrites - CORRECT

d. in muscle, forms T-tubles and sarcoplasmic reticulum

13. second messenger:

a. are the substance that bind with first messenger

b. are hormones secreted by cells in response to stimulation by other hormone.

c. mediate the intracellular responses many different hormones and neuro-transmitters. - CORRECT.

d. are the peropheral proteins of cell membrane

14. The example of negative feed back is:

a. child birth

b. regulation of arterial pressure - CORRECT

c. haemostasis

d. coagulation of blood

15. MITOTIC apparatus consists of:

a. nucleus

b two chromatids

c. two centrioles at opposite poles of nucleus and microtubules connecting them- CORRECT

d. two centrosome lies perpendicular to each other.

16. The enzyme CATALASE present within the peroxisome prevents excessive accumulation of:

a. water

b. hydrogen ions

c. hydrogen peroxide - CORRECT

d. lactic acid

17. in skeletal muscles, agranular endoplasmic reticulum:

a. stores calcium ions - CORRECT

b. synthesizes lipids

c. makes antibodies

d. modifies proteins

18. Drug detoxification occurs in hepatocytes following proliferation of the

a. smooth endoplasmic reticulum - CORRECT

b. endosomes

c. lysosomes

d. rough endoplasmic reticulum

19.exocrine and endocrine glands have extensive:

a. ER

b. golgi apparatus - CORRECT

c. mitochondria

d. peripheral proteins in their cell membrane

20. inclusion bodies are:

a. metabolically active substance

b. lifeless accumulation of material - CORRECT.

c. also called microbodies

d. stores energy sources

21. one organelle that is more acidic than other organelle is:

a. lysosomes- CORRECT

b. ribosomes

c. golgi apparatus

d. mitochondria

22. which of the following are present in neuronal cell body:

a. microtubules

b. neuro filaments

c. nissel bodies

d. all of the above - CORRECT

23. all of the following statements concerning plasma membrane components are true EXCEPT:

a. G- proteins are composed of 3 subunits

b. lipid bilayer has hydrophobic and hydrophilic poles

c. glycocalyx is usually composed of phospholipids - CORRECT

d. gated channels are open only transiently.

24. which statement about nucleolus is not true:

a. it is an inclusion body

b. it is bounded by membrane - CORRECT.

c. it is located within nucleus

d. it is observable during interphase.

25. rough endoplasmic reticulum is indirectly involved in:

a. carbohydrate synthesis

b. lipid synthesis

c. protein synthesis - CORRECT

d. protein degradation.

26. Types of vesicle formed by golgi apparatus is:

a. pinocytic vesicle

b. secretory vesicle- CORRECT

c. excretory vesicle

d. actylcholine vesicle

27. concerning human cells.

a. mitochondria contains single layer of lipid molecule

b. cell membrane is composed of one layer of lipid molecule

c. contains smooth endoplasmic reticulum - CORRECT

d. all are capable of phagocytosis

28. entire human body contains

a. all excitable cells

b. 75- 100 trilion cells - CORRECT.

c. all non-excitable cells

d. 75 trillian cells

29. The organelles present in largest number are:

a. microtubules in muscle spindle

b. mitochodria in hepatic cells - CORRECT

c. ribosomes in neutrophills

d. lysosomes in basal lamina

30. Regarding transport through cell membrane.

a. carrier mediated diffusion in unidirectional

b carrier mediated diffusin require high amount of ATP.

c. ATP binding site of NA-K pump is situated inside the cell - CORRECT.

d. osmotic pressure is required for osmosis

31. following cells are considered to be phagocytic in nature:

a. plasma cells

b. fibroblast

c.kupffer cells - CORRECT

d. lymphocytes

32. regarding digestive vesicles cell all statements are true except:

a. replenish the cellular membrane - CORRECT

b. causes regression of tissue

c. contain bacterial agents

d. are concerned with catabolic functions.

33. interior of cell is negative because of all of the factors except:

a. presence of organelle

b. greater concentration of chloride ion inside cell - CORRECT

c. greater concentration of intracellular proteins

d. due to Na-K ATPase pump

34. Regarding ribosomes:

a. consist of two sub-units of equal sizes

b. it consist of DNA

c. consist of 40% RNA and 60% protein

d. consist of 40% protein and 60% RNA - CORRECT.

35. Which of the following characteristics is shared by the events of pinocytosis and phagocytosis?

a. involve the recruitment of actin filaments - CORRECT

b. occurs spontaneously and non selectively

c. are observed only in macrophages and neutrophils

d. do no require adenosine triphosphate.

36. Which of the following proteins is most likely to be the product of proto-oncogene?

a. cytoskeletal protein

b. sodium channel

c. growth factor receptor- CORRECT

d. myosine light chain.

37. A phospholipid bilayer is most permeable to which of the following?

a. sodium

b. calcium

c. water

e. oxygen - CORRECT

38. which of the following characteristics of a biological cell membrane is most influenced by its cholesterol content?

a. thickness

b. fluidity - CORRECT.

c. ion permeability

d. hydrophobicity

39. The appearance of which of the following distinuishes eukaryotic cells from lower units of life?

a. DNA

B. RNA

C. nucleus - CORRECT

d. membranes

40. " Degeneration" of genetic code occurs during which of the following steps of proteins synthesis?

a. DNA replication

b. transcription

c. post-transcriptional modification

d. translation - CORRECT.

41. Digestion of nutrients in single typical cell is brought about by:

a. ribosomes

b. lysosomes - CORRECT

c. peroxisomes

d. centrosomes

42. Microfilaments and microtublues have all of the following functions EXCEPT:

a. formation of cytoskeleton

b. formation of endoplasmic reticulum between cell membrane and nuclear membrane - CORRECT

c. formation of cilia and ciliated epithelium

d. formation of centriols and mitotic spindle.

43. Lysosomes that contains undigested waste is called

a. primary lysosome

b. secondary lysosome.

c. residual body - CORRECT

d. inactive lysosome

44. vacuoles present in cytoplasm help in

a. storage of nutrients

b. excretion of wastes - CORRECT

c. synthesis of enzymes

d. secretion of enzymes

45. Ribosomes are formed by:

a. golgi apparatus

b. endoplasmic reticulum

c. nucleolus - CORRECT

d. lysosomes.

46. Tight junctions are present in

a. cell membrane

b. renal distal tubule - CORRECT

c. alveolar epithelial cells

d. hepatic cells

47. Pripheral proteins of cell membrane

a. are loosely attached to cell membrane by electrostatic interactions - CORRECT

b. have negative charge

c. act as receptors

d. are embedded in cell membrane

48.steroid hormones, cholesterol synthesizing cells have extensive.

a. smooth endoplasmic reticulum - CORRECT

b. rough endoplasmic reticulum

c. golgi apparatus

d. mitochondria

49.Gap junctions are found in:

a. smooth muscle cells - CORRECT

b. skeletal muscle cells

c. glandular cells

d. ciliated cells

50. "LEAKY " tight junctions are present in:

a. acinar cells

b. axonal cells

c. nuclear membrane

d. gall bladder and renal proximal tubules - CORRECT. Posted by faiza khamissa at 12:37 AM