Cedars-Sinai Medical CenterCapacity Building in Central and Capacity Building in Central and Eastern Europe:Eastern Europe: Research and Research and Innovation Management Innovation Management Education and TrainingEducation and Training

Innovation 2005 November 30, 2005Prague, Czech Republic

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Introduction

Sandor G. Vari, MDInternational Research and Innovation ManagementBurns and Allen Research InstituteCedars-Sinai Medical CenterLos Angeles, CA, USA

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• scientifically advanced

• academically oriented

Innovation Management and Technology Transfer Training (IMTTTM)

The Central and Eastern European Countries are

• but innovation has not been sufficiently rewarded in their transition to the free market system.

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Intellectual property produced by the academic sector continues to be taken without fair compensationbecause the research and academic communities are not well educated about research and innovation management.

Research and Innovation Management

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Cedars-Sinai Medical Center views this research, innovation management and technology transfer collaboration as a long-term collaboration which is intended to help build and enhance:

•innovation management capabilities •internal expertise

in Central and Eastern EuropeanUniversities on a fast track.

Innovation Management and Technology Transfer Training Program in the Central and East European Countries

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In 1998, the US Government and the European Union entered into a research collaboration arrangement.

In 1999, Cedars-Sinai started to explore potential collaborations with European Medical Centers and Biomedical Research Institutes.

Cedars-Sinai, in conjunction with the EU Research and Technology Development Division, developed several project proposals.

Funding for such collaborations could be available through the NIH, NSF and the Fogarty International Center.

Partnership with CEE Universities for Innovation Management and Technology Transfer (IMTT) Training

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February 2001, the first meeting between Central & Eastern European Countries and Cedars-Sinai Medical Center took place.

September 2001, Cedars-Sinai and four Hungarian Universities entered into Research and Technology Transfer Agreements and new partners from other Central European Countries were introduced to the project.

2003 CSMC implemented the “Bridges in Life Sciences Program™”.

2002-2005 Cedars-Sinai and additional CEE Universities entered into Research and Technology Transfer Agreements from Czech Republic, Romania, Slovakia and Slovenia.

Partnership with CEE Universities for Innovation Management and Technology Transfer (IMTT) Training

Bridges in Life Sciences WorkshopsBridges in Life Sciences Workshops

Goals:Goals:

Organize a regional networking forum for CEE.

Enhance research opportunities/adapted to changing needs.

Create new networking structure „Bridge” to create thematic or multidisciplinary networks.

Innovation management and technology transfer training.

Innovation Management and Technology Transfer Training (IMTTTM)

Strengthen Research Collaboration Explore New

Funding Mechanism Preparation of Research

Grant Proposals

Technology Transfer Education

& Training

Research NetworkingMeetings

with various NIH Institutes

THREE PILLARS OF THE WORKSHOPS

Innovation Management and Technology Transfer Training (IMTT™)

Networking Meetings and Training Programs CSMC and NIH/FIC

2003 and 2004

Hungary, Budapest, October 9-11, 2003 (Regional, Multidisciplinary – CSMC/ FIC)

Slovak Republic, Bratislava May 10-11 2004 (Low Birth Weight – CSMC/NICHD)

Czech Republic, Prague May 12-15 2004(Regional, Innovation Management- CSMC/FIC)

Vilnius, Lithuania October 4 2004(Funding Opportunities, Technology Transfer Training - CSMC/NIAID)

Poland, Warsaw October 6 2004(Funding Opportunities, Technology Transfer Training - CSMC/NIAID)

Hungary, Debrecen October 8-9 2004(Cardiovascular Disease, Ophthalmology - CSMC/ NIAID, NHLBI)

Hungary, Szeged 2004 October 11-12 (Innovation Management - CSMC/ NIAID)

Romania, Bucharest October 14-16 2004 (HIV/AIDS - FIC, NIAID, NICHD, NIMH, NIDA)

Networking Meetings and Training Programs CSMC 2005

Czech Republic, Hradec Kralove, April 4-5, 2005(Innovation Management and Technology Transfer Training)

Slovakia, Bratislava, April 6, 2005(Innovation Management and Technology Transfer Training)

Hungary, Pecs, April 8 and June 6, 2005(Innovation Management and Technology Transfer Training)

Hungary, Szeged, June 6, 2005(Innovation Management and Technology Transfer Training)

Ukraine, Lwow, October 3-4, 2005(Innovation Management and Technology Transfer Training)

Romania, Bucharest, October 6-7, 2005(Innovation Management and Technology Transfer Training)

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STRATEGY

Introduce: Education and Training

Involve: Innovation and TechnologyTransfer Partnerships

Implement: Innovation ManagementInfrastructure in Universities and Academic Institutions

International Research and Innovation Management

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1999 2004Phase 1 - Start-Up

A. PartnershipDevelopment(“Bridges In Life

SciencesMeetings”)

Activities- Identify Prospective

Partners- Concept Orientation &

Marketing- Research

Collaborations Identified

Participants:

- Czeh Republic- Hungary- Lithuania- Rumania- Slovakia- Slovenia- Ukraine

Innovation& Tech.Transfer

AgreementCompleted

B. PartnershipDevelopment(“Bridges In Life

SciencesMeetings”)

Activities- Innovation

Management & Tech.Transfer Training

Seminars> In Europe> At CSMC

Participants:

- Czeh Republic- Hungary-Rumania- Slovakia- Slovenia- Ukraine

2006Phase 2 - Transition

CSMCReceivesInvention

DisclosuresFrom

Partners

- Market /PatentAssessmentsCompleted

- ProvisionalPatents

Filed- LicensingAgreements

Explored

IndividualPatents

CEEPartner

CEEPartner

CEEPartner

CEEPartner

CSMC

PortfolioManagement

External“Seed”Funding

CSMCFunding

(If Needed)

2008Phase 3 - Portfolio Optimization

Result #1

Result #2

CEE PartnersConsolidated IP Portfolio

CEEPartner

CEEPartner

CEEPartner

CEEPartner

PortfolioManagement

CSMC

IndividualLicenses

Completed

RoyaltyPymts. ToIndividual

PatentHolders

Royalty Pymts.To CSMC For

IndividualPatents

Fee BasedAccess ToPartners IPPortfolio

- Bio-Tech.- Pharm.- VC’s

Result #3

PatentGroups

Licensed

RoyaltyPymts. Based

On IPOwnership

Fixed % Of AllRoyaltyPymts.

Result #4

DividendReturn Based

on FeePymts. -

Expenses

CEE Partners CSMC

CEE (Owned)Holding Company

Research and Innovation Management

Education and Training (RIMETTM)Innovation Management and Technology Transfer (IMTTTM)

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PHASE 1: Cedars-Sinai Medical Center (CSMC) in 2001 has developed the Innovation Management and Technology Transfer (IMTTTM) Program.

PHASE 2: In 2005, in order to enhance the effectiveness of the project, CSMC implemented the Research and Innovation Management Training Program (RIMETTM) to train: •scientists •physicians •healthcare managers for research and technology transfer management.

PHASE 3: Next step is focused on building self-sufficiency of the CEE Universities by building a Strategic Alliance and Intellectual Property or “IP” Warehouse.TM

Innovation Management and Technology Transfer Training Program in the Central and East European Countries

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PHASE 1

Strategic Alliance and Networking:—Creation of Patent Portfolio—Training

Partner’s role: Equalizing Infrastructure CSMC’s role: Training and Management

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PHASE 1 Innovation Management and Technology Transfer Training (IMTTTM)

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PHASE 1 Innovation Management and Technology Transfer Training (IMTTTM)

During the course of the IMTT Program, Cedars-Sinai and its CEE partners focused their attention on identifying the true training needs in the partner universities and institutions. 

As a part of the IMTT on-site training at the universities trainees develop skills that will enable them to bring back a set of best practices which will fit the organizational structure of their university.

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PHASE 2 “Train the Trainers”

Building Business Strategy:—Creation of Independent Organization—Training of Partners

Partner’s role: Independent Technology Transfer Management

CSMC’s role: Support role

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  PHASE 2

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PHASE 2 Research, Innovation Management Education and Training (RIMET)

CSMC IMTT Training Model

Innovation Management and Technology Transfer (IMTT) Training INTRODUCE, INVOLVE, IMPLEMENT

Research Management Training Human Subject Research Training Clinical Trial Management Training Graduate Medical Education Ph.D. Program in Economics and Jurist Doctor (JD) with a Concentration in

Intellectual Property

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In addition, by improving their own competency in the area, they can then help other Central European Universities to implement Research and Innovation Management Programs.

The need for skilled trainers continues to grow in order to meet the challenges and success of the Strategic Alliance for Research and Innovation Management and IP Warehousing.

PHASE 2 Innovation Management and Technology Transfer Training (IMTTTM)

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Phase 3

Business Enterprise :—Developing Consortium

Partner’s role: Self Management of Inventions CSMC’s role: Technology Transfer Outsource

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  Phase 3

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PHASE 3: Strategic Alliance with Central & Eastern European Universities

• Building a shared patent portfolio– a so called “IP Warehouse™”– by CSMC and its Central and East European partner universities strengthens the presence of the partners in the Global Market.

• The strategic alliance allows each partner to receive a fair share of value from technologies created by the talented researchers and scientists throughout Central and East Europe.

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Three Wheels of the CSMC – CEE Strategic Alliance

Capacity B

uilding

Implement Research and Innovation Management Infrastructure

Increase Scientific and Innovation Output

Continuing EducationResearch Networking

Build IP WarehouseBring CEE Partners’ IP to the Global Market

“The only way to win in this business is to have alliances”