catalogue in pdf (ht15)
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Katalog kurser på forskarnivå
HT15
# Människans biologi eller sjukdomslära * Allmänvetenskapliga kurser1202 Human Cell Culture. Methods and Applications 20150921 20150925 (Engelska)1383 Basic Course in Medical Statistics * 20151130 20151211 (Engelska)1386 Philosophy of science and research ethics * 20151102 20151106 (Engelska)1386 Philosophy of science and research ethics * 20150907 20150911 (Engelska)1386 Philosophy of science and research ethics * 20151130 20151204 (Engelska)1386 Medicinsk vetenskapsteori och forskningsetik * 20151005 20151009 (Svenska)1391 Writing science and information literacy * 20151123 20151204 (Engelska)1392 Vetenskapligt skrivande och informationskompetens * 20151026 20151106 (Svenska)1472 Infections in the Tropics 20151014 20151231 (Engelska)1496 Flow cytometry: from theory to application 20150921 20150925 (Engelska)1507 Rörelseapparaten klinisk utvärdering av funktion och behandling 20151012 20151016(Svenska)1559 Experimental techniques in study of metabolic and endocrine disorders 20151130 20151204(Engelska)1577 Epidemiology I: Introduction to epidemiology 20150902 20150911 (Engelska)1579 Biostatistics I: Introduction for epidemiologists * 20150916 20151006 (Engelska)1594 Tumor immunology and immune therapy of cancer 20151116 20151120 (Engelska)1595 Molecular Immunology 20151012 20151023 (Engelska)1622 Epidemiology II. Design of epidemiological studies 20150831 20150909 (Engelska)1626 Cytokines in inflammation 20151116 20151127 (Engelska)1627 Clinical and experimental neuroimmunology 20151012 20151016 (Engelska)1635 Basic course in Tumor Biology and Oncology 20150831 20150911 (Engelska)1794 Study design in clinical research 20151116 20151204 (Engelska)1814 Methods for Qualitative Content Analysis 20150929 20151125 (Engelska)1873 Quality of life as an outcome measure in care sciences 20151116 20151127 (Engelska)1974 Phenotyping of genetically engineered mice 20151207 20151211 (Engelska)1999 Embryology I 20151012 20151016 (Engelska)2000 Advanced seminars in Tumor Biology 20150901 20151222 (Engelska)2001 What is life? The future of biology. 20150916 20160217 (Engelska)2044 Pathology # 20151019 20151030 (Engelska)2074 Current Topics in Infection Biology 20150902 20151216 (Engelska)2132 Forskningsetik * 20150825 20150915 (Svenska)2133 Vetenskapsteori * 20151006 20151201 (Svenska)2135 Infectious Disease Epidemiology 20151012 20151016 (Engelska)2144 To communicate science in different contexts * 20150916 20151001 (Engelska)2154 Cardiovascular Epidemiology 20151019 20151023 (Engelska)2166 Basic Tumor Histopathology 20150914 20150925 (Engelska)2176 Cellular and molecular infection biology 20151026 20151106 (Engelska)2186 How to make genetically modified mice for immunological research 20150907 20150911(Engelska)2188 Developmental biology for regenerative medicine 20150831 20150911 (Engelska)2283 Live cell imaging 20151005 20151016 (Engelska)2291 Clinical achievements of reproductive medicine 20150921 20150925 (Engelska)2302 Basic immunology 20150915 20151029 (Engelska)2348 Functional Fluorescence Microscopy Imaging (fFMI) in biomedical research 20151102 20151113(Engelska)2381 Survey of Molecular Endocrinology 20150928 20151009 (Engelska)2407 Aktuell Omvårdnadsvetenskap teori och praxis 20151002 20151120 (Svenska)2416 Causal Inference for Epidemiological Research 20151130 20151204 (Engelska)2418 Methods in molecular biology and their applications in medical research 20150907 20150918(Engelska)2430 Principles of nucleic acid structure 20151116 20151204 (Engelska)2433 Clinical Research in Lipid Metabolism 20151019 20151023 (Engelska)2454 Public health intervention and implementation research 20151019 20151120 (Engelska)2484 Thrombosis and Hemostasis, from mechanisms to therapies 20151102 20151106 (Engelska)2498 Obesity basic science, clinical and epidemiological aspects 20151116 20151120 (Engelska)2515 Cancer cell energy metabolism 20151102 20151106 (Engelska)2518 Basics of Qualitative research 20150914 20150918 (Engelska)2525 Cellular Reprogramming from basal mechanisms to medical applications 20150914 20150918(Engelska)2526 Neuropschopharmacology 20151123 20151201 (Engelska)2536 The major global infectious diseases: tuberculosis and HIV 20151123 20151127 (Engelska)2561 Writing Science and Information Literacy * 20150824 20151016 (Engelska)2570 Introduction to R statistical analysis for biologists 20151109 20151113 (Engelska)
2583 Noncoding RNA and cancer 20151130 20151204 (Engelska)2600 Neurogenetics 20150928 20151002 (Engelska)2605 Brain development and Neurodevelopmental disorders 20150921 20150925 (Engelska)2608 Mechanisms of Gene Regulation in Metabolism 20151105 20151111 (Engelska)2609 Basic Course in Medical Statistics a distance course * 20150921 20151002 (Engelska)2616 Frontiers in Cogntive Neuroscience 20150914 20150918 (Engelska)2618 Write your research results and get them published * 20151012 20151023 (Engelska)2618 Write your research results and get them published * 20150928 20151009 (Engelska)2618 Write your research results and get them published * 20151116 20151127 (Engelska)2618 Write your research results and get them published * 20150907 20150918 (Engelska)2618 Write your research results and get them published * 20151130 20151211 (Engelska)2624 Brain circuits 20150907 20150911 (Engelska)2629 Neurodegenerative disorders I From molecule to treatment 20151005 20151009 (Engelska)2630 Neurodegenerative disorders II cellular and molecular mechanisms 20151012 20151016(Engelska)2644 Human physiology an overview # 20150914 20150925 (Engelska)2644 Människans fysiologi en översikt # 20150907 20150918 (Svenska)2647 Surgical Techniques in Rat and Mouse 20150921 20150925 (Engelska)2652 Mesenchymal stem cells biology and clinical potential. 20151012 20151016 (Engelska)2654 Grounded Theory in Health Research 20151130 20151211 (Engelska)2657 Introduktionskurs i R datahantering, analys och grafisk presentation 20151105 20151127(Svenska)2666 Metoder för statistisk analys: Från variansanalys till multilevel modeling * 20151012 20151030(Svenska)2668 Evidensbaserad verksamhet inom hörsel, öron, språk och tal 20150901 20151218 (Svenska)2671 Tumor microenvironment 20151123 20151127 (Engelska)2686 Introduction to teaching at KI * 20150902 20151007 (Engelska)2688 Multidisciplinary perspectives on active ageing research 20150921 20151217 (Engelska)2690 Basic Laboratory Safety * 20151109 20151116 (Engelska)2690 Basic Laboratory Safety * 20150928 20151005 (Engelska)2693 Measuring physical activity with focus on wearable monitors applications for clinical andepidemiological studies 20151023 20151123 (Engelska)2704 Metoder för systematisk litteraturöversikt 20150907 20151215 (Svenska)2717 Hematopoiesis and hematopoietic stem cells in health and disease 20151026 20151030(Engelska)2721 Culture and Brain 20150901 20160215 (Engelska)2743 Writing skills for science * 20150813 20150816 (Engelska)2780 The Developing Brain 20150831 20150904 (Engelska)2787 Present your research! * 20150831 20151110 (Engelska)2787 Present your research! * 20150825 20151109 (Engelska)2790 How to conduct systematic reviews and metaanalyses 20151019 20151104 (Engelska)2794 Medical developmental biology 20150817 20150821 (Engelska)2796 Introduction to Stata for epidemiologists 20150914 20150915 (Engelska)2797 Biostatistics II: Logistic regression for epidemiologists * 20151207 20151216 (Engelska)2827 Människans Fysiologi en översikt # 20151216 20160115 (Svenska)2833 Introduction to Quantile Regression and Related Methods 20151102 20151106 (Engelska)2839 Philosophy of science and research ethics, statistics and oral scientific communication * 20150921 20151023 (Engelska)2841 The third dimension of nuclear functions 20151012 20151016 (Engelska)2843 The cell cycle 20151116 20151120 (Engelska)2844 Exploring entrepreneurial opportunities in research * 20151116 20151120 (Engelska)2845 Cellbased heart regeneration 20150928 20151002 (Engelska)2846 Integration of Neuroimaging and Cognition in Normal Aging and Dementia 20151109 20151113(Engelska)2849 Cancer and cancer stem cells 20151116 20151120 (Engelska)2852 Initiating entrepreneurial thinking in connection to research 20150914 20151218 (Engelska)2854 Translational lung cancer research 20151021 20151022 (Engelska)2855 Digital photomicrography 20151019 20151023 (Engelska)2856 Teaching and Learning in Higher Education: educational course for doctoral students a distancecourse * 20150911 20151217 (Engelska)2857 Orientation in qualitative research methods 20151105 20151119 (Engelska)2858 Longitudinal data analysis classical and modern statistical methods 20151102 20151113(Engelska)2859 DNA damage and maintenance of genome integrity 20151012 20151016 (Engelska)2860 Extracellular vesicles: a tool for diagnostics and therapy. 20151109 20151113 (Engelska)
2861 Biomedical Ecology The microbiota in health and disease 20151123 20151127 (Engelska)2865 Regulatory RNAs in Development, Disease and Evolution 20151007 20151016 (Engelska)
Title : Human Cell Culture. Methods and Applications
Kursnummer : 1202Antal högskolepoäng : 1.5Datum : 20150921 20150925Språk : EngelskaNivå : Doctoral levelKursansvarig institution : The institute of Environmental MedicineSärskild behörighet : Kursens lärandemål : After the course, the students should be well acquianted with the theory andpractice of cell culture. Knowledge in basic and stateoftheart methods applied to cell cultures. To havedeveloped skills for bench work with cell cultures on an individual basis.Kursens innehåll : Cell culture reflecting stem, transit amplifying, differentiated and terminallydifferentiated tissue states; Monolayer and organotypic culture involving one or more cell types.Applicability of cell cultures as alternatives to laboratory animal experiments. Mechanisms regulating cellgrowth and viability, differentiation and apoptosis. Assessment of cell transformation to immortal andmalignant phenotypes. Isolation of specific cells, e.g., epithelial cells,characterisation of cultured cells.Handling and sterile techniques, choice of materials and media for cell culture, e.g., serumdependent vs.serumfree culture conditions. Cell cloning and gene transfer. Practical handling of cultures:thawing/freezing, passage, expansion and longterm storage. Handling of normal and tumor tissue foroptimizing obtainment of cultures. Tissue engineering practices. Transcriptomics, proteomics andinformatics methods for biomedical research with cell lines. Discussion of participants own cultureexperience and problems.Arbetsformer : Lectures, laboratory work, ITuse and group discussions on pitfalls and possibilities withcell cultures.Examination : Literature studies and oral presentation of results for the course participants.Obligatoriska moment : Presence at scheduled lectures and time allocated for oral examination ofallparticipants is compulatory. Opportunity to follow missed lectures is possible at repeat courses twice ayear (graduate courses 1202 and 1862). Based on documented participation in the lectures, the oralexamination can be arranged separately with the course organizer. Antal studenter : 10 15Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information :
Kursansvarig : Roland GrafstromInstitutet för miljömedicin
Kontaktpersoner : Johanna BergmanInstitutet för miljömedicin
Nobels väg 13
17177Stockholm
Roland GrafstromInstitutet för miljömedicin
Title : Basic Course in Medical Statistics
Kursnummer : 1383Antal högskolepoäng : 3.0Datum : 20151130 20151211Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Learning, Informatics, Management and EthicsSärskild behörighet : Kursens lärandemål : The course participants shall after the course be able to perform and interpret basicdescriptive statistics from frequency tables and graphical presentations, perform and interpret results frombasic statistical analysis and test (like ttest, chisquare test, nonparametric test and Regression analysis),as well as have enhanced their ability to recognize, understand and critically view the statistics beingpresented in articles within the medical field of research.Kursens innehåll : The course is an introduction to basic statistical principles and how statistics play a partin medical research. Concepts being treated are hypothesis, type I error, type II error, estimates,measurement of dispersion, regression analysis, inference making and how to present the results.Arbetsformer : This course is a so called TeamBased Learning (TBL)course. TBL is a special form oflearning that integrates individual assessment and group work with immediate feedback. Focus will be onsolving statistical problems in a group/team setting. This two weeks course consists of online preparationthrough video lectures and exercises, and several TBL sessions (in class meeting). The in class meetingswill correspond to twothree full days each course week. The time in between meetings will be spentreading the course material, and preparing for the assessment and group application exercises.Examination : Individual and group assessments and active participation during the group applicationexercises. Obligatoriska moment : In class attendance during TBL sessions are mandatory for passing grade. If thestudent misses more than one TBL occasion, the doctoral student must take the course again.Antal studenter : 40 50Urval av studenter : Date for registration as a doctoral student (priority given to earlier registration date).Please make sure that you have entered the correct registration date for doctoral education in yourpersonal profile.Övrig information : This course is a TBLcourse. TBL, TeamBased Learning, is a special form of learningthat integrates individual work, group work and immediate feedback. Focus will be on solving statisticalproblems in group/team setting. The course has the same content and length as the original course 1383.The course will consist of 2 3 full days per week for two weeks.
Kursansvarig : Mesfin TessmaInstitutionen för lärande, informatik, management och etik
Kontaktpersoner : Margareta KrookBrandtInstitutionen för lärande, informatik, management och etik52487118Margareta.Krook[email protected]
Title : Philosophy of science and research ethics
Kursnummer : 1386Antal högskolepoäng : 1.5Datum : 20151102 20151106Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Learning, Informatics, Management and EthicsSärskild behörighet : NoKursens lärandemål : The objective of this course is for the doctoral student to gain a basicunderstanding of the philosophy of science and insight into and understanding of key ethical theories,principles and guidelines related to research and thereby be given the opportunity to reflect on the ethicalaspects of his/her own research. The objective is also to provide the doctoral student with an understandingof what is good research practice, and also an understanding of the boundary between what is ethicallyacceptable or unacceptable in terms of experimentation with human beings and animals. After completingthe course, the research student should: be able to give an account of the positions relative to thephilosophy of science and research ethical theories, principles and, to some extent current guidelines knowthe most important terms within the philosophy of science and demonstrate knowledge of common problemsituations in research ethics and of the ethical tools used to manage conflicts concerning research ethics be able to analyse ethical conflicts in research and see the connection between the philosophy of scienceand research ethics be able to construct sustainable research ethical arguments for or against a specificcourse of action have developed an ethical approach to researchKursens innehåll : The course includes the following: Key ethical principles and theories of research Fundamental values for empirical research, and standards of good scientific practice Experiments onhumans, including a review of informed consent, its ethical basis, and the pros and cons of practices forinformed consent Ethical tests and guidelines on how to conduct ethical research, such as the HelsinkiDeclaration Ethics and the use of laboratory animals, including arguments for and against using animals forresearch purposes, as well as the three Rs Handling of authorship in scientific writing Conflicts of interestin research Key scientific terms and positionsArbetsformer : Introducing lectures, group work and general discussions.Examination : The doctoral students write a short informal essay on a scientific or research ethical themerelated to their own research. Obligatoriska moment : Attendance is mandatory for the group work and general discussions. If thestudent is absent, he or she can compenste by handling in written answers concerning the cases that havebeen discussed.Antal studenter : 30 35Urval av studenter : Selection is based on 1) the date of PhD registration (where prior registration dateshave priority) 2) curriculum relevant to the candidate's PhD project (as motivation).Övrig information :
Kursansvarig : Gert HelgessonInstitutionen för lärande, informatik, management och etik
Kontaktpersoner : Emma KarlssonInstitutionen för lärande, informatik, management och etik08524 83 [email protected]
Title : Philosophy of science and research ethics
Kursnummer : 1386Antal högskolepoäng : 1.5Datum : 20150907 20150911Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Learning, Informatics, Management and EthicsSärskild behörighet : NoKursens lärandemål : The objective of this course is for the doctoral student to gain a basicunderstanding of the philosophy of science and insight into and understanding of key ethical theories,principles and guidelines related to research and thereby be given the opportunity to reflect on the ethicalaspects of his/her own research. The objective is also to provide the doctoral student with an understandingof what is good research practice, and also an understanding of the boundary between what is ethicallyacceptable or unacceptable in terms of experimentation with human beings and animals. After completingthe course, the research student should: be able to give an account of the positions relative to thephilosophy of science and research ethical theories, principles and, to some extent current guidelines knowthe most important terms within the philosophy of science and demonstrate knowledge of common problemsituations in research ethics and of the ethical tools used to manage conflicts concerning research ethics be able to analyse ethical conflicts in research and see the connection between the philosophy of scienceand research ethics be able to construct sustainable research ethical arguments for or against a specificcourse of action have developed an ethical approach to researchKursens innehåll : The course includes the following: Key ethical principles and theories of research Fundamental values for empirical research, and standards of good scientific practice Experiments onhumans, including a review of informed consent, its ethical basis, and the pros and cons of practices forinformed consent Ethical tests and guidelines on how to conduct ethical research, such as the HelsinkiDeclaration Ethics and the use of laboratory animals, including arguments for and against using animals forresearch purposes, as well as the three Rs Handling of authorship in scientific writing Conflicts of interestin research Key scientific terms and positionsArbetsformer : Introducing lectures, group work and general discussions.Examination : The doctoral students write a short informal essay on a scientific or research ethical themerelated to their own research. Obligatoriska moment : Attendance is mandatory for the group work and general discussions. If thestudent is absent, he or she can compenste by handling in written answers concerning the cases that havebeen discussed.Antal studenter : 30 35Urval av studenter : Selection is based on 1) the date of PhD registration (where prior registration dateshave priority) 2) curriculum relevant to the candidate's PhD project (as motivation).Övrig information :
Kursansvarig : Gert HelgessonInstitutionen för lärande, informatik, management och etik
Kontaktpersoner : Emma KarlssonInstitutionen för lärande, informatik, management och etik08524 83 [email protected]
Title : Philosophy of science and research ethics
Kursnummer : 1386Antal högskolepoäng : 1.5Datum : 20151130 20151204Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Learning, Informatics, Management and EthicsSärskild behörighet : NoKursens lärandemål : The objective of this course is for the doctoral student to gain a basicunderstanding of the philosophy of science and insight into and understanding of key ethical theories,principles and guidelines related to research and thereby be given the opportunity to reflect on the ethicalaspects of his/her own research. The objective is also to provide the doctoral student with an understandingof what is good research practice, and also an understanding of the boundary between what is ethicallyacceptable or unacceptable in terms of experimentation with human beings and animals. After completingthe course, the research student should: be able to give an account of the positions relative to thephilosophy of science and research ethical theories, principles and, to some extent current guidelines knowthe most important terms within the philosophy of science and demonstrate knowledge of common problemsituations in research ethics and of the ethical tools used to manage conflicts concerning research ethics be able to analyse ethical conflicts in research and see the connection between the philosophy of scienceand research ethics be able to construct sustainable research ethical arguments for or against a specificcourse of action have developed an ethical approach to researchKursens innehåll : The course includes the following: Key ethical principles and theories of research Fundamental values for empirical research, and standards of good scientific practice Experiments onhumans, including a review of informed consent, its ethical basis, and the pros and cons of practices forinformed consent Ethical tests and guidelines on how to conduct ethical research, such as the HelsinkiDeclaration Ethics and the use of laboratory animals, including arguments for and against using animals forresearch purposes, as well as the three Rs Handling of authorship in scientific writing Conflicts of interestin research Key scientific terms and positionsArbetsformer : Introducing lectures, group work and general discussions.Examination : The doctoral students write a short informal essay on a scientific or research ethical themerelated to their own research. Obligatoriska moment : Attendance is mandatory for the group work and general discussions. If thestudent is absent, he or she can compenste by handling in written answers concerning the cases that havebeen discussed.Antal studenter : 30 35Urval av studenter : Selection is based on 1) date of PhD registration (where prior registration dates havepriority) 2) the curriculum relevant to the candidate's PhD project (as motivation).Övrig information :
Kursansvarig : Gert HelgessonInstitutionen för lärande, informatik, management och etik
Kontaktpersoner : Emma KarlssonInstitutionen för lärande, informatik, management och etik08524 83 [email protected]
Title : Medicinsk vetenskapsteori och forskningsetik
Kursnummer : 1386Antal högskolepoäng : 1.5Datum : 20151005 20151009Språk : SvenskaNivå : ForskarnivåKursansvarig institution : Department of Learning, Informatics, Management and EthicsSärskild behörighet : NejKursens lärandemål : Målet med kursen är att den forskarstuderande ska få en grundläggandevetenskapsteorisk förståelse och inblick i och förståelse av centrala forskningsetiska teorier, principer ochriktlinjer och därmed få möjlighet att reflektera över etiska aspekter av den egna forskningen. Målet ärockså att den forskarstuderande ska få en förståelse av vad som är god forskningssed, samt var gränsengår för vad som är etiskt oacceptabelt både vad gäller försök med människor och med djur. Denforskarstuderande ska efter att ha gått kursen: kunna redogöra för vetenskapsteoretiska positioner samtforskningsetiska teorier, principer och, i viss mån, riktlinjer känna till centrala vetenskapsteoretiska termersamt vanliga forskningsetiska problemsituationer och de etiska verktygen för att hantera forskningsetiskakonflikter kunna analysera forskningsetiska konflikter och se kopplingen mellan vetenskapsteori ochforskningsetik kunna ge hållbara forskningsetiska argument för eller mot ett förfarande ha utvecklat ettforskningsetiskt förhållningssätt Kursens innehåll : Kursen innehåller följande moment: Centrala forskningsetiska principer och teorier Grundläggande värderingar för empirisk forskning samt normer för god vetenskaplig sed Försök medmänniskor, inklusive en genomgång av informerat samtycke, dess etiska grund och för och nackdelar medrutiner för informerat samtycke Etikprövningar och forskningsetiska riktlinjer, såsomHelsingforsdeklarationen Försöksdjursetik, innefattande argument för och emot att använda djur förforskningsändamål, samt de tre R:en Hantering av vetenskapligt författarskap Intressekonflikter iforskningen Centrala vetenskapliga termer och positioner Arbetsformer : Introducerande föreläsningar, grupparbeten och plenumdiskussioner.Examination : Deltagarna skriver en egen vetenskapsteoretisk eller forskningsetisk reflektion över sitteget forskningsprojekt.Obligatoriska moment : Vid frånvaro krävs särskilt utförliga svar på de fall som diskuterats.Gruppdiskussionerna och plenumdiskussionerna är obligatoriska.Antal studenter : 30 35Urval av studenter : Urvalet baseras på 1) datum för doktorandregistrering (där tidigareregistreringsdatum har förtur) 2) kursplanens relevans för den sökandes doktorandprojekt (enligtmotivering). Övrig information :
Kursansvarig : Gert HelgessonInstitutionen för lärande, informatik, management och etik
Kontaktpersoner : Emma KarlssonInstitutionen för lärande, informatik, management och etik08524 83 [email protected]
Title : Writing science and information literacy
Kursnummer : 1391Antal högskolepoäng : 3.0Datum : 20151123 20151204Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Karolinska Institutet University LibrarySärskild behörighet : Kursens lärandemål : After the course, you should be able to demonstrate: understanding of how towrite an original scientific article and submit it for publication the ability to write other types of textsrequired for a scientific career the ability to give, take and make use of constructive criticism the ability tosearch and manage the medical sciences literature in a structured way the ability to use resources whichfacilitate choosing a journal to publish your research in the ability to describe aspects of postpublicationevaluation and processing of the medical sciences literature Kursens innehåll : Scientific writing, Popular science writing, Grant writing, Thesis writing, Figures andtables, Revising structure and style, Ethical issues in writing, Publication process, Principles of medicalinformation retrieval, Databases, Reference management, Choosing a journal and Evaluating publishedscienceArbetsformer : Individual writing and rewriting, lectures, working in pairs and groups, webbasedteaching, demonstrations, computer exercises and individual study. NOTE THAT THIS IS THE KISOLNACAMPUS VERSION OF THE COURSE. THERE IS ALSO AN ONLINE VERSION (COURSE CODE 2561)INTENDED PRIMARILY FOR DOCTORAL STUDENTS HAVING DIFFICULTIES TO ATTEND THE KISOLNACAMPUS COURSES.Examination : Writing a grant application (including references) with popular science summary andrewriting based on peer and teacher feedback. There are also three assignments in which participantsdemonstrate development of their information literacy.Obligatoriska moment : The course writing assignment is obligatory and has to be submitted about 10days BEFORE course start. All scheduled teaching is compulsory (except where clearly stated otherwise).Absence can usually be compensated for by reading and individual work after consultation with courseleaders. Antal studenter : 30 34Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information :
Kursansvarig : David HerronKarolinska Institutet Universitetsbibliotek08524 841 [email protected]
Berzelius 7B
17177Stockholm
Kontaktpersoner :
Title : Vetenskapligt skrivande och informationskompetens
Kursnummer : 1392Antal högskolepoäng : 3.0Datum : 20151026 20151106Språk : SvenskaNivå : ForskarnivåKursansvarig institution : Karolinska Institutet University LibrarySärskild behörighet : Kursens lärandemål : Efter kursen ska du kunna visa: förståelse för hur man skriver en vetenskapligartikel och skickar in den för publicering förmåga att skriva andra typer av texter som en del i detvetenskapliga arbetet förmåga att ge, ta emot och använda konstruktiv kritik förmåga att söka ochhantera den vetenskapliga litteraturen på ett strukturerat sätt förmåga att använda olika resurser somstöd vid valet av tidskrift att publicera sig i förmåga att beskriva aspekter av hur man kan utvärderapublicerad vetenskap Kursens innehåll : Scientific writing, Popular science writing, Grant writing, Thesis writing, Figures andtables, Revising structure and style, Ethical issues in writing, Publication process, Principer för medicinskdatabassökning, Databaser, Referenshantering, Val av tidskrift och Evaluera publicerat vetenskap.Arbetsformer : Individuella skrivuppgifter och revision, föreläsningar, par och grupparbeten, webbaseratlärande, demonstrationer, datorövningar och individuella studier. OBS. KURSDELEN SOM BEHANDLARVETENSKAPLIGT SKRIVANDE HÅLLS PÅ ENGELSKA OBS. DET FINNS OCKSÅ EN ONLINE VERSION AVKURSEN PÅ ENGELSKA (KURSKOD 2561) AVSEDD PRIMÄRT FÖR DOKTORANDER MED SVÅRIGHETER ATTVARA MED PÅ KI CAMPUS SOLNA KURSERNA. Examination : Skrivande av en anslagsansökan (på engelska) med populärvetenskaplig sammanfattning(på svenska) samt bearbetning (med referenser) baserat på "peer" och lärarkommentarer. Det finns ocksåtre uppgifter som demonstrerar utvecklingen av deltagarnas informationskompetens. Obligatoriska moment : Skrivuppgiften är obligatorisk och måste inlämnas cirka 10 dagar FÖRE kursensbörjan. Samtliga schemalagt undervisningpass är obligatoriska. Frånvaro kan oftast kompenseras eftersamtal med kursledarna. Antal studenter : 30 34Urval av studenter : Urvalet baseras på 1) kursplanens relevans för den sökandes doktorandprojekt(enligt motivering), 2) datum för doktorandregistrering (där tidigare registreringsdatum har förtur)Övrig information :
Kursansvarig : David HerronKarolinska Institutet Universitetsbibliotek08524 841 [email protected]
Berzelius 7B
17177Stockholm
Kontaktpersoner :
Title : Infections in the Tropics
Kursnummer : 1472Antal högskolepoäng : 7.5Datum : 20151014 20151231Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Medicine, SolnaSärskild behörighet : Kursens lärandemål : To understand the conditions under which the major infectious diseases in thetropics arise and how they are prevented/treated locally. To understand the conditions for biomedicalresearch in a low or middle income country from within and to be able to account for some of the currentlocal research issues. To be able to discuss these issues with health care professionals and researchers in asatisfactory way.Kursens innehåll : Field studies under local staff in low or middle income country and Swedish supervisionat the primary,secondary and tertiary health care level. Joint seminars (mutual presentations of research projects) at local research institute. Students will present their findings of elective projects at the end of thecourse. Arbetsformer : Bedside and benchside teachings at hospitals and polyclinics/health care centers.Seminars. Elective works with oral and written presentations. Field studies will take place in in a low ormiddle income country. Examination : Formative assessment of ability to discuss the specific issues encountered with health careprofessionals and researchers. Presentation of elective projects to Swedish faculty. Every student will beexamined individually. Obligatoriska moment : Field studies, joint seminars at local research institute, presentation of electiveprojects. Absence cannot be compensated for.Antal studenter : 5 10Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : The course starts with five twohour evening lectures covering the major tropicalinfections such as malaria, helminth infections, tuberculosis/leprosy and leishmania trypanosomiasis. Thesewill take place Wednesday evenings between 17.3019.00 hrs, starting Oct 14, 2015 at the Dept ofInfectious Diseases, Karolinska Hospital,Solna. One additional session will be devoted to designing electiveprojects to be conducted during the field session in Ethiopia.<br /> <br /> Field session in Ethiopia isplanned for between Nov 28 Dec 21, 2015.<br /> <br /> Final course week will be between Dec 28 Dec31, 2015 when elective projects will be reported/discussed and a written quiz issued. <br /> <br /> A feeof US$1500 will be required to contribute towards full board accommodation and local transport costs. Anofficial receipt of the paid sum will be issued for putative reimbursement by the home Department.International travel and tuition/bench fees will be covered by the course grant.
Kursansvarig : Sven BrittonInstitutionen för medicin, [email protected]
Oxtogsgränd 1
11157Stockholm
Kontaktpersoner : Anne RasikariInstitutionen för medicin, Solna08517 718 [email protected]
B3:03
Title : Flow cytometry: from theory to application
Kursnummer : 1496Antal högskolepoäng : 1.5Datum : 20150921 20150925Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Medicine, SolnaSärskild behörighet : Kursens lärandemål : Through this oneweek course, the participants will acquire the knowledge of flowcytometry principles. They will know flow cytometric sample preparation and analysis, protocol setup, aswell as data interpretation.Kursens innehåll : The course covers basic knowledge and main applications of flow cytometry, andcontains both lectures and laboratory/group work. Experts in different fields of flow cytometric applicationare invited to give the lectures. The participants will be able to learn: a) Principles of flow cytometry:working mechanisms of flow cytometer; molecular and cellular probes for flow cytometry; quality control;and safty procedures and intrument maintainance. b) Basic skills: flow cytometric protocol design; samplehandling and storage; data processing and analysis, and data presentation. c) Major applications of flowcytometry in biomedical research: leukocyte phenotyping, endothelial cell analysis, stem cell analysis,apotosis, platelet measurement, cell function analysis (including membrane potential, oxidative metabolism,intracellular calcium mobilization, pH, and intracellular organelles), as well as nucleic acid analysis.Arbetsformer : The course includes 28 hr lectures and 12 hr handson lab work.Examination : The exam will consist two parts: a 30min written test on flow cytometric principles; and a60 min handson lab work examining flow cytometric lab skillsObligatoriska moment : The participants must attend handson lab sections during two afternoons. Thestudents who have missed these sections can book extra lab section time within 4 weeks to compensate theabsence.Antal studenter : 20 32Urval av studenter : The course used to receive far more applications than the maximal course slots of32. Selection of the participants is thus needed and made according to: 1) How relevant is flow cytometryto the thesis project? 2) How urgent is the flow cytometry training for her/his project work? 3) Has thestudent applied for the course before?Övrig information : The course will be held during week 39 (Sept 2125, 2015; 9:0016:30). Lecture hallbooked: Block Salen, T4:00 at Karolinska University HospitalSolna. Lectures will be given by 1415lecturers, usaually half of them from institutions outside KI, with one or two from abroad. All the lecturersare wellestablished flow cytometrists on their lecture subjects. The course has been given 12 times/yearat KI for 14 years. It has been highly appreciated by the participants through the years, with a mediangeneral satisfaction score never below 8 (out of 9; referred to paperbased course evaluation between20012013), and highly remarked with the websurvey (2014).
Kursansvarig : Nailin LiInstitutionen för medicin, Solna08[email protected]
Clinical Pharmacology UnitKarolinska University HospitalSolna17176Stockholm
Kontaktpersoner : Nailin LiInstitutionen för medicin, Solna08[email protected]
Clinical Pharmacology UnitKarolinska University HospitalSolna17176Stockholm
Title : Rörelseapparaten klinisk utvärdering av funktion ochbehandling
Kursnummer : 1507Antal högskolepoäng : 1.5Datum : 20151012 20151016Språk : SvenskaNivå : ForskarnivåKursansvarig institution : Department of Molecular Medicine and SurgerySärskild behörighet : Kursens lärandemål : Kunskaper: Kunskaper om metoder, försöksplanering och statistisk bearbetning avmaterial inom kliniska forskningsprojekt som berör rörelseorganens sjukdomar och skador. Färdighet:Kunna framställa och värdera en forskningsplan för ett projekt inom rörelseorganens sjukdomar.Förhållningssätt: Ha lärt sig ett vetenskapligt och kritiskt förhållningssätt till den vetenskapliga litteratureninom området för rörelseorganens sjukdomar och skador.Kursens innehåll : Klinisk utvärdering av funktion och behandling inom rörelseorganens sjukdomar ochskador.Arbetsformer : Katedrala föreläsningar, gruppövningar kring ett tänkt forskningsprojekt.Examination : Kursdeltagarna redovisar de forskningsprojekt som de arbetat med under kursen ochprojektet diskuteras med övriga kursdeltagare och en lärarpanel bestående av kursledningen och specielltinbjudna experter. Under denna diskussion testas kursdeltagarnas kunskaper, färdigheter,värderingsförmågor och förhållningssätt utifrån lärandemålenObligatoriska moment : Antal studenter : 5 20Urval av studenter : Urvalet baseras på 1) kursplanens relevans för den sökandes doktorandprojekt(enligt motivering), 2) datum för doktorandregistrering (där tidigare registreringsdatum har förtur)Övrig information : Kunskaper: Kunskaper om metoder, försöksplanering och statistisk bearbetning avmaterial inom kliniska forskningsprojekt som berör rörelseorganens sjukdomar och skador. Färdighet:Kunna framställa och värdera en forskningsplan för ett projekt inom rörelseorganens sjukdomar.Förhållningssätt: Ha lärt sig ett vetenskapligt och kritiskt förhållningssätt till den vetenskapliga litteratureninom området för rörelseorganens sjukdomar och skador. Klinisk utvärdering av funktion och behandlinginom rörelseorganens sjukdomar och skador. Katedrala föreläsningar, gruppövningar kring ett tänktforskningsprojekt. Kursdeltagarna redovisar de forskningsprojekt som de arbetat med under kursen ochprojektet diskuteras med övriga kursdeltagare och en lärarpanel bestående av kursledningen och specielltinbjudna experter. Under denna diskussion testas kursdeltagarnas kunskaper, färdigheter,värderingsförmågor och förhållningssätt utifrån lärandemålen
Kursansvarig : Lars WeidenhielmInstitutionen för molekylär medicin och kirurgi
Kontaktpersoner :
Title : Experimental techniques in study of metabolic andendocrine disorders
Kursnummer : 1559Antal högskolepoäng : 1.5Datum : 20151130 20151204Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Molecular Medicine and SurgerySärskild behörighet : Kursens lärandemål : After the course the students will be able i) to measure glucose transport inisolated rodent skeletal muscle; ii) to measure lipolysis in isolated adipocytes; iii) to dissect out mousepancreatic islets and measure the insulin release; iv) to judge and analyze obtained data. The students willbe able to describe the possibilities and limitations of the above techniques. Kursens innehåll : The aim of this course is to provide methodology to solve preclinical problems inmetabolic and endocrine research. The course is laboratory based, aiming to give all participants hands onexperience with isolation of pancreatic islets, skeletal muscle and adipose tissue. Theoretical and practicalconsiderations will be presented and discussed.Arbetsformer : The course meets for five days full time, including three full day laboratory practicalsessions. The first day will consist of several lectures to give a background to the metabolic questions whichwill be addressed in the practical part of the course. Our aim is to provide the student with a hands onexperience of each technique covered. In order to achieve this, for the laboratory work the courseparticipants will be subdivided into smaller groups.Examination : The laboratory notebook examination from each student, a short oral presentation of theproject work and a short summary of the project work by each group.Obligatoriska moment : All three laboratory tasks are compulsory; as an exception, a written task couldbe given to a participant to compensate absence.Antal studenter : 9 18Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information :
Kursansvarig : Alexander ChibalinInstitutionen för molekylär medicin och [email protected]
Kontaktpersoner :
Title : Epidemiology I: Introduction to epidemiology
Kursnummer : 1577Antal högskolepoäng : 1.5Datum : 20150902 20150911Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Medical Epidemiology and BiostatisticsSärskild behörighet : Kursens lärandemål : After successfully completing this course students are expected to be able to: giveexamples of the contribution of epidemiology to science and discuss the importance of epidemiology as aresearch discipline. estimate and in a general way interpret measures of disease occurrence and measuresof association, and describe how a specific measure is governed by the study design. explain strengths andweaknesses of common epidemiological study designs. identify and explain possible sources of bias inepidemiological studies. describe theoretical models for causation and discuss the principles of causalmechanisms. apply knowledge of epidemiological concepts when critically reviewing scientific literature. Learning outcomes are classified according to Bloom´s taxonomy: knowledge, comprehension, application,analysis, synthesis, and evaluation.Kursens innehåll : The course gives an introduction to epidemiological theory and practice. It comprisesbasic principles regarding design, interpretation, and analysis of epidemiological studies. It introduces theconcept of causation, concepts related to measures of disease occurrence and measures of association,common designs for epidemiological studies (with main focus on cohort studies), and the role of bias.Arbetsformer : The course focuses on active learning, i.e. putting knowledge into practice and criticallyreflecting upon the knowledge, rather than memorising facts. Different strategies for teaching and learningwill be used, such as lectures, group discussions and various forms of group exercises on selected topics.Examination : To pass the course, the student has to show that the learning outcomes have beenachieved. Assessments methods used are group assignments along with written and oral individual tasks.The examination is viewed as contributing to the development of knowledge, rather than as a test ofknowledge. Students who do not obtain a passing grade in the first examination will be offered a secondchance to resubmit the examination within two months of the final day of the course. Students who do notobtain a passing grade at the first two examinations will be given top priority for admission the next timethe course is offered. Obligatoriska moment : The examination tasks are compulsory. Antal studenter : 12 25Urval av studenter : Selection will be based on 1) the relevance of the course for the applicant's project(according to written motivation), 2) date for registration as a doctoral student (priority given to earlierregistration date). Submit a completed application form and give all information requested, including ashort description of current research, motivation for attending and an account of previous courses.Övrig information : Course dates are: September 2, 4, 7, 9 and 11. The course is extended over 2 weeks(but still 5 full course days) in order to promote reflection and reinforce learning
Kursansvarig : Fang FangInstitutionen för medicinsk epidemiologi och biostatistik
Kontaktpersoner : Gunilla Nilsson RoosInstitutionen för medicinsk epidemiologi och biostatistik08524 822 [email protected]
Title : Biostatistics I: Introduction for epidemiologists
Kursnummer : 1579Antal högskolepoäng : 3.0Datum : 20150916 20151006Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Medical Epidemiology and BiostatisticsSärskild behörighet : Kursens lärandemål : After successfully completing this course students should be able to: define theconcept of probability, laws of probability, and make simple probability calculations. (S2) suggest astatistical distribution to describe a naturally occurring phenomonen and evaluate the appropriateness ofthe distribution given real data. (S3) present appropriate descriptive statistics for an epidemiologicalstudy. (S2) explain the difference between hypothesis testing and interval estimation and the relationbetween pvalues and confidence intervals. (S3) suggest an appropriate statistical test for a comparison oftwo groups, perform the hypothesis test using standard statistical software, and interpret the results. (S3) estimate and interpret three alternative measures of association between binary exposures and binaryoutcomes and discuss the relative merits of each measure for a given research question. (S3) explain theconcept of confounding in epidemiological studies and demonstrate how to control/adjust for confoundingusing stratified analysis. (S2) explain the basis of the linear regression model, fit a linear regression modelusing standard statistical software, assess the fit of the model, and interpret the results. (S2) Learningoutcomes are classified according to Bigg's structure of the observed learning outcome (SOLO) taxonomy:(S1) unistructural, (S2) multistructural, (S3) relational, and (S4) extended abstract.Kursens innehåll : The course introduces classical statistical concepts and methods with emphasis onmethods used in epidemiology and public health. Topics covered include: the importance of statisticalthinking; types of data (nominal, binary, discrete and continuous variables); data summary measures;contingency tables; graphical representations; notions of probability; probability models (distributions);principles of statistical inference; parameter estimation (mean, proportion (prevalence), incidence andratios); concepts of confidence intervals and hypothesis tests; and a general introduction to correlation andlinear regression models. Arbetsformer : Lectures, exercises focusing on analysis of real data using statistical software, exercisesnot requiring statistical software, group discussions, literature review.Examination : The course grade is based mainly on a written examination, but group tasks and individualwritten assignments are also used. The course is divided into two parts, and each part will be examinedseparately. To pass the course, a student must pass both parts. Students who fail will be offered a reexamination within 2 months of the final day of the course. Students who fail the reexam will be given toppriority for admission the next time the course is offered. If the course is not offered during the followingtwo academic terms then another reexamination will be scheduled within 12 months of the final day of thecourse. Obligatoriska moment : Antal studenter : 12 25Urval av studenter : Selection will be based on 1) the relevance of the course for the applicant's project(according to written motivation), 2) date for registration as a doctoral student (priority given to earlierregistration date). Submit a completed application form and give all information requested, including ashort description of current research, motivation for attending and an account of previous courses.Övrig information : The course is extended over time in order to promote reflection and reinforcelearning. The course will be held the dates: September 16, 17, 18, 21, 22 and examination September 24(week 1), and September 28, 29, 30 and October 1, 2 and examination October 6 (week 2). We stronglyrecommend prior knowledge in Stata software.
Kursansvarig : Yudi PawitanInstitutionen för medicinsk epidemiologi och biostatistik
Kontaktpersoner : Gunilla Nilsson RoosInstitutionen för medicinsk epidemiologi och biostatistik08524 822 [email protected]
Title : Tumor immunology and immune therapy of cancer
Kursnummer : 1594Antal högskolepoäng : 1.5Datum : 20151116 20151120Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of OncologyPathologySärskild behörighet : Kursens lärandemål : After the course is completed the students will be able to (1) explain importantaspects of tumor immunology, (2) indicate advantages and disadvantages of different immune therapystrategies, (3) explain mechanisms of immune escape, 4) hypothesize how different immunebasedregimens may affect clinical outcome in patients with cancer. Kursens innehåll : This course covers basic and applied immunology and a current review of experimentalresearch and clinical application of tumor immunology. Both preclinical and clinical aspects of cancervaccination, adoptive cell therapy, and antibody therapy will be discussed. Development of novel therapiesthrough modification of immune cell subsets will be presented. Features of the tumor microenvironment,cancerassociated inflammation, immune surveillance and escape, and immunosuppression will also bediscussed. Planning, performing, and monitoring of clinical trials are included in the course as well. One totwo days are dedicated to lectures by invited international experts from the field.Arbetsformer : Lectures, seminars, group discussions and casestudies. Examination : Oral group presentation and individual assignment based on casestudies. Every studentwill be individually assessed.Obligatoriska moment : Antal studenter : 12 32Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : Full day lectures/assignments from Monday to Friday at the Lecture hall of the CancerCenter Karolinska (R8:00). There will at least 4 invited international speakers.
Kursansvarig : Rolf KiesslingInstitutionen för onkologi[email protected]
Kontaktpersoner : Andreas LundqvistInstitutionen för onkologipatologi
Jeroen MeliefInstitutionen för onkologipatologi
Kristina WittInstitutionen för onkologipatologi
Title : Molecular Immunology
Kursnummer : 1595Antal högskolepoäng : 3.0Datum : 20151012 20151023Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Microbiology, Tumor and Cell BiologiSärskild behörighet : Kursens lärandemål : After the course, the student should be able to relate their own research project tothe cuttingedge developments in other areas of immunology research. Furthermore, they should havegained increased experience in preparing and presenting novel information about an immunological problemor a specific technique to their fellow students.Kursens innehåll : The course is given during 2 weeks. Invited national and international lecturers givetheir views on selected problems, or techniques, in immunology. The seminars take off from basic facts, butthe speakers are encouraged to move on to current problems, and to focus on both scientific andmethodological aspects. To merit 3 full ECTS points for the course, students will be asked, in a groupproject work, to study an immunological method or problem deeply at the theoretical level and lectureabout this method to the fellow students. At the end of the course, a written and an oral presentation isexpected from all students.Arbetsformer : Lectures, group work, oral and written presentationsExamination : Evaluation of oral and written presentation of project work. Specific contibution of eachgroup participant will be investigated and evaluated. A short written exam based on the content of thecourse.Obligatoriska moment : Oral presentations at the end of the course. Written project work and writtentest. If a student misses the presentation, a special presentation with the course leader will be arranged.Antal studenter : 10 30Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : The course will be held on weekdays with most lectures from 9.00 to 12.00. Alllectures will be held at MTC Nobelsväg 16 on the Solna Campus. The course will also include invitedlecturers from universities outside Sweden who are experts in their field
Kursansvarig : Jonathan CoquetInstitutionen för mikrobiologi, tumör och cellbiologi
Kontaktpersoner : Robert WallinInstitutionen för medicin, Huddinge08[email protected]
Benedict ChambersInstitutionen för medicin, Huddinge
Title : Epidemiology II. Design of epidemiological studies
Kursnummer : 1622Antal högskolepoäng : 1.5Datum : 20150831 20150909Språk : EngelskaNivå : Doctoral levelKursansvarig institution : The institute of Environmental MedicineSärskild behörighet : Knowledge in epidemiology equivalent to "Epidemiology I: Introduction toepidemiology" or corresponding courses.Kursens lärandemål : After successfully completing this course you as a student are expected to be ableto: in a selfdirected manner, formulate the principles of different types of common epidemiological studydesigns. mainly independently, explain how a specific measure of disease occurrence and measure ofassociation is governed by the study design. in a selfdirected manner, explain and discussepidemiological concepts, including accuracy, in the context of different epidemiological study designs. draw conclusions from epidemiological scientific papers and to review and criticize these regarding studydesign, results and accuracy. Learning outcomes are classified according to Bloom's taxonomy:knowledge, comprehension, application, analysis, synthesis, and evaluation. Kursens innehåll : The course focus on issues related to study design (primarily casecontrolmethodology), study base, study efficiency, matching in epidemiological studies, induction time,interpretation of epidemiologic evidence. Arbetsformer : Lectures, group discussions and various forms of group exercises on selected topics, willbe used. The course focuses on active learning, i.e. putting knowledge into practice and critically reflectingupon the knowledge, rather than memorising facts. Examination : To pass the course, the student has to show that the learning outcomes have beenachieved. Assessments methods used are group tasks along with written and oral individual tasks.Theexamination is viewed as a contributing to the development of knowledge, rather than as a test ofknowledge. Students who do not obtain a passing grade in the first examination will be offered a secondexamination within two months of the final day of the course. Students who do not obtain a passing gradeat the first two examinations will be given top priority for admission the next time the course is offered. Obligatoriska moment : Only the examination tasks are compulsory.Antal studenter : 12 25Urval av studenter : Prerequisite knowledge Epidemiology I: Introduction to epidemiology orcorresponding. We also strongly recommend Biostatistics I: Introduction for epidemiologists or equivalent.Selection will be based on 1) the relevance of the course for their research 2) the stated motivation forattending the course. Please submit a completed application form and give all information requested incl. ashort description of current research, motivation for attending and an account of previous courses taken.Övrig information : The course is extended over time in order to promote reflection and reinforcelearning. Course dates are: August 31, September 2, 4, 7 and 9.
Kursansvarig : Karin LeanderInstitutet för miljömedicin08[email protected]
Box 210 (Nobels väg 13), KI
171 77Stockholm
Kontaktpersoner : Ida Kettley CronfalkInstitutet för miljömedicin
Title : Cytokines in inflammation
Kursnummer : 1626Antal högskolepoäng : 3.0Datum : 20151116 20151127Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Medicine, SolnaSärskild behörighet : NoneKursens lärandemål : Objectives At the end of the course the participant should be able to: selectadequate experimental methods to analyze cytokines based on specific scientific questions understandthe relevance of cytokines in the context of their research project compare and contrast the function ofcytokines in different organs and different diseases explain how a disease can be treated with drugstargeting cytokines hypothesize future treatment of a disease, where the modification of a cytokinepattern is the targetKursens innehåll : Learning how to measure cytokine responses in different ways and understanding thefunction of cytokines in immunological networks.Arbetsformer : The course is partly theoretical, partly practical, where lectures and laboratorydemonstrations are integrated. Time is also allocated for discussing of lab results and lectures, and forgroup assignment.Examination : To pass the course the participant has to: actively participate in the discussions duringthe course present a seminar where different aspects of a cytokine will be discussed, i.e. disease involvedand overall biological effects, and describe and discuss methods to detect it within the methods presentedduring the course. take a written exam during the last day of the course. This exam will cover thecourse's theoretical and practical content.Obligatoriska moment : Practical sessions are compulsory, unless stated not. Absence from severalpractical sessions cannot be compensated for, but absence from one theoretical session can becompensated for in subsequent sessions.Antal studenter : 15 25Urval av studenter : Priority will be given to 1) PhD students working in the field of immunology 2) earlystage students with at least basic knowledge in immunology (year 1 2), and 3) expressed writtenmotivation to attend the course.Övrig information : The aim of the course is to provide an increased understanding of the function ofcytokines in the context of healthy immune system and in different disease contexts. Note: This is not abasic course of immunology. Location: KI campus Solna. Time: 09.0016.00 all days. Course contentincludes lectures from invited experts and KI experts, and local staff are also involved in practical work.
Kursansvarig : Andre OrtliebInstitutionen för klinisk neurovetenskap
Kontaktpersoner : Heidi WähämaaInstitutionen för medicin, Solna
Title : Clinical and experimental neuroimmunology
Kursnummer : 1627Antal högskolepoäng : 1.5Datum : 20151012 20151016Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Clinical NeuroscienceSärskild behörighet : Kursens lärandemål : After this course the students should be able to: (i) describe the basic clinicalcharacteristics of the major neuroinflammatory diseases; (ii) design experiments using animal models forneuroinflammatory diseases in rats and mice, compare models and discuss their advantages andlimitations, (iii) evaluate and interpret new findings and recent scientific papers in the field and (iv)speculate on molecular mechanisms underlying neuroinflammatory disease and hypothesize how knowledgeon these mechanisms can enable therapy and prevention.Kursens innehåll : The course includes the overview of clinical symptoms, signs, pathology, treatmentsand diagnostic criteria for the most important neuroimmunological conditions including Multiple Sclerosis,Myasthenia Gravis, GuillainBarré Syndrome, Alzheimer¿s disease as well as infections, trauma, tumors andpain. Also included is an overview of experimental models of neuroimmunological diseases, with anemphasis on techniques for genetic analysis (intercrosses, congenics, transgenics etc). Key molecularconcepts in neuroinflammation are covered such as immune mechanisms of disease as well as tissuedegeneration/regeneration. Different techniques used to study neuroinflammation are discussed such asimaging and flow cytometry. Arbetsformer : The course combines: (i) traditional lectures given by experts in the field, consisting of amixture of both clinicians as well as basic researchers covering diseases, technological aspects or basicprocesses in neuroimmunology; (ii) an individual assignment followed by an interactivepresentation/discussion on the last day. The assignment will consist of a presentation of a highimpactscientific paper relevant to the student¿s own research topic and that is of importance for theneuroimmunology field. Examination : Examination will be based on the presentation of the own individual assignment and thesubsequent discussion during the last day of the course (please see "Teaching and learning activities") andthe feedback given to other students on their assignments. In their presentation, students should be able tocomment on their article of choice in the context of the items described above under "learning outcomes".Guidelines for the preparation of the assignment will be sent out to the students two weeks before the startof the course. Obligatoriska moment : All lectures and individual presentations are compulsory. Compensation forabsence can be discussed with the course directors.Antal studenter : 10 25Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : This course is part of both the Neuroscience and the Allergy, Immunology andInflammation Doctoral Programmes Time: MondayFriday, 9:0017:00; Location: Center for MolecularMedicine (CMM), Karolinska University Hospital, Solna, building L8, lecture hall/seminar room; Speakerslast year included Prof Jan Hillert (MS genetics), Docent Adnane Achour (MHCTCR interaction), Prof TomasOlsson (MS), Dr Rayomand Press (GBS), Prof Fredrik Piehl (neuroprotection), Prof. Dr. Frauke Zipp(University of Mainz; CNSimmune cell interaction); Prof. Burkhardt Becher (University of Zurich; Tumors inthe CNS)
Kursansvarig : Xingmei ZhangInstitutionen för klinisk neurovetenskap
CMM
Stockholm
Kontaktpersoner : Andre OrtliebInstitutionen för klinisk neurovetenskap
Pernilla StridInstitutionen för klinisk neurovetenskap
Maja JagodicInstitutionen för klinisk [email protected]
Neuroimmunology Unit, CMM, L8:04
17176Stockholm
Title : Basic course in Tumor Biology and Oncology
Kursnummer : 1635Antal högskolepoäng : 3.0Datum : 20150831 20150911Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of OncologyPathologySärskild behörighet : Kursens lärandemål : This is a basic course for all PhDstudents in the field. After the course the studentswill have an understanding of the cancer problem, the modern view what cancer is, from a clinical and basicscience view. You will get the basic foundations of cancer biology as well as aquire some ability to discussand understand advanced problems in cancer biology. You will have an idea which are the current mostimportant problems to solve in cancer, to improve diagnosis, prevention, treatment and quality of life. Theover all aim of the course is to form a bridge between preclinical and clinical aspects of tumor biology andoncology for PhD students and to provide the students an understanding of all aspects of the cancerproblem. This course is a basic introduction to modern cancer research and is recommended to all PhDstudents within basic and clinical cancer research. Kursens innehåll : The course will describe the causes as well as the consequences of the transformationof a normal cell into its malignant counterpart, in order to create an understanding of cancer frommolecule to patient, eventually also discussing the management and treatment of malignant diseasesThetopics of the course include genetics, the cell cycle, apoptosis, immunology, diagnostics and treatment, alltopics presented from the cancer perspective. There will be focus on a few malignant diseases, described inmore detail serving as models for basic concepts of Tumor Biology and Oncology, including moleculargenetics, curative treatment and palliative care, psychosocial aspects of cancer, ethics and epidemiology. All seminars and demonstrations are compulsory, also some lectures, as well as the written examination.Single missed occasions can be compensated during the course after discussion with te course director. Arbetsformer : The course consists of lectures, group seminars, group discussions and demonstrations.Full time during two consecutive weeks. Examination : Written examination with a focus on understanding of concepts, relations and how and howproblems are dealt with in cancer research. Obligatoriska moment : This course is full time for two weeks. All seminars and demonstrations arecompulsory, also some lectures, as well as the written examination. Single missed occasions can becompensated during the course after discussion with te course director.Antal studenter : 20 35Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date) Övrig information : The course is scheduled full time for 2 weeks. Nonclinicians will be offered to joinMeetapatient sessions.
Kursansvarig : Svetlana Bajalica LagercrantzInstitutionen för onkologipatologi08[email protected]
Trastvägen 24
18279Stocksund
Kontaktpersoner : Daria GlaessgenInstitutionen för onkologipatologi
Title : Study design in clinical research
Kursnummer : 1794Antal högskolepoäng : 4.0Datum : 20151116 20151204Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Molecular Medicine and SurgerySärskild behörighet : Kursens lärandemål : After completion of the course the students should be able to: 1) Independentlyplan and produce a study protocol including a thorough methodological evaluation and choice of appropriatestudy design. 2) Critically reflect on other students individual project work in a scientifically constructiveway. 3) Interpret and critically evaluate scientific studies relevant to the course content. Kursens innehåll : The course is designed for PhDstudents, in particular those who are at an early stageof their research education, and those with an interest in conducting clinical research. The content of thecourse is as follows: 1) Basic terms in epidemiology and clinical study design, 2) Measures of diseaseoccurrence and incidence, causality, 3) Observational studies cohort and casecontrol studies, 4)Systematic and random errors, 5) Experimental studies, randomised clinical trials, 6) Quality of life inclinical research, 7) Examination and course evaluation. Throughout the course, the students will work onan individual project (examination 1) for peerreview (examination 2). Further, students will criticallyreview and discuss relevant scientific articles (examination 3). Arbetsformer : Lectures, seminars, individual article review, group discussions and homework tasks will beused. The course focuses on active learning, i.e. putting knowledge into practice and critically reflectingupon the knowledge, rather than memorising facts. Therefore, much of the focus of the course is on theindividual project where students are required to develop a full study protocol including several importantaspects covered in the lectures, article reviews and group discussions. Students will also peerrevieweachothers projects and this will form the basis for the final examination seminar. Examination : To pass the course the student must actively participate in the course and pass theexaminations: 1) Individual project work: To develop a written comprehensive yet concise study protocolincluding several important aspects study design as discussed during the course; 2) Peerreview of otherstudents projects followed by oral presentation own project and opposition of other students projects duringthe group examination; 3) Critically review scientific articles relevant to the course content and participateactively in the seminars. Obligatoriska moment : Compulsory attendance includes the scheduled lectures and seminars. Absencewill need to be replaced by individual assignments following discussion with the course coordinator, e.g.article reviews, with written or oral followup.Antal studenter : 18 25Urval av studenter : Selection will be based on 1) Date of registration as a PhD student 2) suitability ofPhD project 3) The motivation to attend the course.Övrig information :
Kursansvarig : Nele BrusselaersInstitutionen för molekylär medicin och [email protected]
UGIR Norra Stationsgatan 67
17176Stockholm
Kontaktpersoner : Kalle MälbergInstitutionen för molekylär medicin och kirurgi
Title : Methods for Qualitative Content Analysis
Kursnummer : 1814Antal högskolepoäng : 4.5Datum : 20150929 20151125Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Neurobiology, Care Sciences and SocietySärskild behörighet : Kursens lärandemål : After completing the course the student will be able to: * critically comment onliterature describing the development and method of content analysis. * choose an adequate design forhis/her own data. * describe the different elements of the analysis. * carry out the analysis. * criticallyevaluate the weaknesses and strengths of the method of analysis.Kursens innehåll : Development from a quantitative to a qualitative tradition of content analysis Designand choice of analysis Different elements of the analysis Application and critically evaluation Arbetsformer : The course includes lectures, seminars and individual assignments. The students will inproject work during the whole course with support from lectures, individual literature assignments applycontent analysis in their own research and reflect on that application in a critical way. Examination : The students will finally in their project work demonstrate their knowledge andunderstanding of content analysis by submitting a paper containing the use of the analysis with regard tothe learning outcomes.Obligatoriska moment : The course in its whole needs active involvement of the students throughparticipation in the various types of teaching.Antal studenter : 15 20Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : The dates for the course are: September 2930, October 2021 and November 2425,Alfred Nobels allé 23, KI campus Huddinge. Course leaders: Kenneth Asplund and Ella Danielson
Kursansvarig : Lena KochInstitutionen för neurobiologi, vårdvetenskap och samhä[email protected]
Kontaktpersoner : Miriam Entesarian MatssonInstitutionen för neurobiologi, vårdvetenskap och samhälle
Title : Quality of life as an outcome measure in care sciences
Kursnummer : 1873Antal högskolepoäng : 3.0Datum : 20151116 20151127Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Neurobiology, Care Sciences and SocietySärskild behörighet : Kursens lärandemål : After the course, the students should be able to critically review research papersdescribing quality of life results and to design a study with quality of life as an outcome measure. Thisincludes phrasing research questions, choosing appropriate instruments, timing of assessments andprocedure as well as choosing methods for analysis. Furthermore should students be able to interpret anddiscuss results from studies of quality of life. Kursens innehåll : The concept quality of life and healthrelated quality of life will be discussed to giveinsights into these concepts. Aditionally the criticism against these concepts and their measurement will beaddressed.The course will further include phrasing research questions, choosing appropirate instruments,designing studies measuring quality of life (timing of assessments and procedure), choice of methods foranalysis, and interpretation of results. Arbetsformer : The course is divided in two parts, the first part consist of three fulltime days and thesecond part of two fulltime days, three weeks later. The course is based on lectures during morningsessions, which will be followed up in groupseminars in the afternoons. Between the two parts of thecourse students are required to hand in one homework task which will constitute the examination. Examination : The examination consists of a review of a research proposal. The task will be introducedduring the first part of the course. Obligatoriska moment : Groupseminars are compulsory and absence from them will be made up with aessaywriting on the topics that were to be discussed in the groupseminar. Antal studenter : 15 25Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : Course dates: November 1617, 2627. The course will take place at Alfred NobelsAllé 23 in Huddinge. <br>A mix of learning activities will be used such as lectures, seminars, work ingroups and individual assignments. The topics that will be covered include the concept quality of life, designand sample selection, data collection relating to psychometric properties of the instruments the studentsare using in their own research, analysis and reporting of results. Students will in groups scrutinize eachother's research proposals which will be presented the last day of the course as part of the courseexamination assignment. Students are also asked to hand in a written individual assignment within oneweek of the last course day.
Kursansvarig : Lena WettergrenInstitutionen för neurobiologi, vårdvetenskap och samhälle08[email protected]
Kontaktpersoner :
Title : Phenotyping of genetically engineered mice
Kursnummer : 1974Antal högskolepoäng : 2.0Datum : 20151207 20151211Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Comparative medicineSärskild behörighet : Kursens lärandemål : Mål för kunskap och förståelse Efter kursen skall studenterna kunna redogöra förfenotypning av genetiskt modifierade möss, beskriva systematisk och standardiserad fenotypsanalys avbåde transgena och knock in/outmöss. Studenten skall kunna redovisa för olika strategier för framställningav genetiskmodifierade möss, avelsproblematik, samt för tekniker och medel för undersökning av bådeenklare parametrar och mer specialiserade funktioner såsom beteende, kardiovaskulär fysiologi,neurobiologi och utvecklingsbiologi samt för djurskyddsaspekter. Mål för praktiska färdigheter Efter kursenskall studenten kunna identifiera målorgan för fenotypanalys Efter kursen skall studenten kunna genomförapraktiska undersökningar av genetiskt modifierade möss (obduktionsteknik). Efter kursen skall studentenkunna identifiera och särskilja mellan olika dataanalyser.Kursens innehåll : Denna kurs syftar till att visa hur genetiskt modifierade möss kan fenotypas på ettstrategiskt sätt; genom urval av relevanta "endpoints" och med användande av så få djur som möjligt,genom planering av olika testar som ska genomföras. Den ger baskunskaper i systematisk fenotypsanalysav både transgena och knockin/out möss. Kursen belyser relevanta delar av musens biologi och fysiologi,strategier för framställning av genetiskmodifierade möss, avelsproblematik, samt redogör för tekniker ochmedel för undersökning av både enklare parametrar och mer specialiserade funktioner såsom beteende,kardiovaskulär fysiologi, neurobiologi och utvecklingsbiologi. Kursen omfattar laborationer(obduktionsteknik), demonstrationer av olika moment. Arbetsformer : Kursen omfattar föreläsningar, laborationer, demonstrationer och grupparbete medseminarieuppgifter. Kursen går heltid och dagtid. Kursspråket är engelska.Examination : Lärandemål för kunskap och förståelse examineras genom redovisning av grupparbete. Obligatoriska moment : Grupparbeten och avslutande seminarier är obligatoriska. Bortvaro under kursenkompenseras enligt instruktioner från kursansvarig.Antal studenter : 10 20Urval av studenter : The applicants will be first selected for the relevance of the course to their researchprojects. Then will the date for registration as a PhD student have priority.Övrig information : The course will take place at Comparative Medicine Learning Lab in Solna. It is a oneweek course with full time studies. International lecturers in the subject like Cory Baryton, AssociateProfessor in Molecular and Comparative Pathobiology from John Hopkins University and Björn Rozell,Professor in Laboratory Animal Pathology at University of Copenhagen will be present among others.
Kursansvarig : Raoul KuiperInstitutionen för laboratoriemedicin
Kontaktpersoner : Dude GigliottiKomparativ [email protected]
von Eulers väg 4a, plan 4
171 77STOCKHOLM
Title : Embryology I
Kursnummer : 1999Antal högskolepoäng : 1.5Datum : 20151012 20151016Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Biosciences and NutritionSärskild behörighet : Kursens lärandemål : At the conclusion of this course students should be have a good understanding of: Why in vitro systems are suboptimal in producing viable human embryos relative to development in vivo Main components of the culture system (culture media, tissue culture plastics, gases, incubators,workstations, laboratory environment, input materials) Physicalchemical properties of culture system(osmolarity and pH of culture media, temperature, light levels) and how they can be influenced Constitution of tubal and uterine fluids and the evolution of culture media used in ART programmes as wellas nutritional requirements of the various cell stages from gamete to blastocyst Tissue culture vessels Functional characteristics of different tissue culture incubators Functional characteristics of differentworkstations for ART and their benefits The influence of the laboratory and clinic environment on embryoculture The influence of the quality of the input material on outcomes in ART The morphology ofoocytes, zygotes and cleavage stage embryos as well as morulae and blastocysts Developmentalmilestones Predictors of developmental potential Biochemical tests for predicting developmentalpotential The use of ultrasound to assess oocyte quality Student should be aware of the generalaspects and implication of the stem cells research and the potentiality that this represent for clinicalapplication Morphological aspects of the blastocysts for derivation of ICM and Derivation methods Characterization of the embryonic stem cells and the importance of the pluripotency of these cells Thedifferent differentiations assay on stem cells and what is ongoing in this field The immunorejectionproblem and the production of isogonics embryonic stem cells by somatic cell nuclei transfer or therapeuticclone (SCNT) Finally the students will improve their capacity to produce coherent, logical and conciseexplanations of data and concepts both written and oral, through consideration of the course material. Students will also develop their ability to criticize scientific literature related with ART and reproductionphysiology in a constructive and informed fashionKursens innehåll : Divide in lectures and laboratory work Sperm theory (lecture) 1. Anatomy of the testis,sperm production and maturation, fertilization. 2. Cryopreservation of spermatozoa. 3. Sperm preparationfor IVF and ICSI, criteria for ICSI. Embryology ( Lecture) 1. Follicle growth and maturation, ovulation. 2.Cell biology and oocyte genetics. 3. Embryo development invitro, morphological evaluation of embryos. 4Cryopreservation of embryos, theory and practice. 5. Embryonic stem cells. 6. Selection of embryos fortransfer and cryopreservation. Laboratory 1. How to work with sperm, oocytes and embryos. 2.Manipulation and training with mouse oocytes and mouse embryo handling. 3. Micromanipulationtechniques, presentation. 4. Micromanipulation training. ICSI and embryo biopsy. Genetics (Lecture) 1.Genetic aspects of prenatal diagnostics and PGD. 2. Cloning techniques. Course test, evaluation,discussions and closing of course.Arbetsformer : Course organization The course runs for one weeks with lectures before lunch and practicaltraining in the afternoons. José Inzunza and Julius Hreinsson are responsible for organizing the lectures andliterature projects; and the practical training of the participants and the laboratory work. Teachinglaboratories at Södertörns Högskola will be used for the training in embryological techniques.Examination : Writing individual.Obligatoriska moment : The laboratory parts are obligatory. Not attendance of the laboratory activity;student should present a literature work related with the subject of the missing activity.Antal studenter : 10 17Urval av studenter : The selection is based on the usefulness of the course for the doctoral students'research projects, and the written motivation of the applicants, as to why they want to take the course. Övrig information : The course will be held at Karolinska Institute, Department of Biosciences andNutrition, NOVUM, Huddinge
Kursansvarig : Jose InzunzaInstitutionen för biovetenskaper och näringslära08585 850 [email protected]
Hälsovägen 7, Novum
141 86
Stockholm
Kontaktpersoner : Kenny RodriguezwallbergInstitutionen för onkologipatologi0858580000kenny.rodriguez[email protected]
ReproduktionsmedicinKarolinska Universitetssjukhuset Huddinge141 86Stockholm
Title : Advanced seminars in Tumor Biology
Kursnummer : 2000Antal högskolepoäng : 3.0Datum : 20150901 20151222Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Microbiology, Tumor and Cell BiologiSärskild behörighet : Kursens lärandemål : As a result of the course particiants will be able to understand and discussadvanced problems in cell and tumor biology beyond that of textbooks. The participants will improve theircapacity to evaluate and discuss problem solving amd which methods to choose, outside their own area ofcompetence. In particular they shall be able to discuss and evaluate new data in these areas. Participantswill get an uptodate overview of cutting edge knowledge beyond textbooks, due to the rapid progress ofthe field. This is achieved by seminars lead by national or international scientists, and with teachers amongthe course organizers. Questions and discussion after the presentation by the speaker. Kursens innehåll : The course will cover the frontiers of research in some essential parts of tumor biologyand experimental oncology. Subjects that are usually covered deal with cell cycle, apoptosis, signaltransduction, cancer genetics, epigenetics incl histone regulation, cancer stem cells, proteomics incluingubiquitin regulation, tumor immunology, infections and cancer, mathematical modelling, angiogenesis, cellcell communication, tumor heterogeneity, tisue biology and tumor microenvironment, new treatmentconcepts, and problems in clinical cancer research. Arbetsformer : Lectures and/or seminars in groups followed by discussions including the students once aweek. Occasionally litterature studies with research articles associated with the seminars. Totally appr 18weeks with some 20 seminars, and two meetings in a smaller group.Examination : Written examination at the end of the course («home exam»). Questions of «essay»type totest understanding and scientific maturity, incl some tests of subject knowledge. In addition to the homeexam the participants are evaluated according to their activity during the seminars' Q&Asessions/discussions.Obligatoriska moment : The seminars and the meetings in smaller groups are compulsory. Lack ofattenandance at single events will be compensated in ways agreed with the course leaders.Antal studenter : 8 20Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : Seminars on Tuesdays every week between 13.00 appr 14.30 at Seminar room A302, MTC, Nobels väg 16, KI Campus, Solna. In addition Bonus seminars may be offered occassionally as areplacement for the Tuesday seminars.
Kursansvarig : Ingemar ErnbergInstitutionen för mikrobiologi, tumör och [email protected]
Box 280, Karolinska Institutet
17177Stockholm
Kontaktpersoner : Anita GöndörInstitutionen för mikrobiologi, tumör och cellbiologi08 524 862 [email protected]
Margareta WilhelmInstitutionen för mikrobiologi, tumör och cellbiologi08524 874 [email protected]
Elena KashubaInstitutionen för mikrobiologi, tumör och cellbiologi08524 862 [email protected]
Title : What is life? The future of biology.
Kursnummer : 2001Antal högskolepoäng : 2.0Datum : 20150916 20160217Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Microbiology, Tumor and Cell BiologiSärskild behörighet : Kursens lärandemål : After the course students shall be able to discuss: 1. Theories about complexity ofbiological systems 2. How biocomplexity can be studied. 3. What is the place of computational simulationsin modern biology? How simulations can be done? What the predictive power is. How mathematics can beused in simulating biological phernomena. 4. How one understands the organizational principles of biologicalsystems. If selforganization is a field for study or just a trivial phenomenon. 5. How evolotionary theorycan be formalized into mathematical models. 6. If quantum mechanical theory can have a role in molecularbiology. 7. How genetic information can be converted to mechanical or electrical force in biological system. The students will also aquire an understanding of the conceptual and technical challenges in futurebiomedicine and advance your ability to ask scientific questions and identify significant and possible areas for problem solving. Kursens innehåll : Inspired by the seminal book by Erwin Schrödinger What is life? published 60 yearsago we will adress this question again, in view of the impressive development since then. There are manynew concepts to consider in the future of biology, such as the consequencies of the omics era, complexity,computation and simulation, as well as the role of mathematicss and physics in biological theory. Thecourse will cover areas such as biocomplexity, quantum mechanical theory in biology, computation andsimulation (in silico biology), organization of biological systems, causality in biology, how does chemistrybecome electric and magnetic forces and evolutionary theory in the light of molecular biology. Leadingscientists with an overview perspective will be invited to discuss in the seminar form the challenges thatmeet us today in biology, as a result of the omics era, the availability of large amounts of data as a resultof high throughput techniques, and the possibilities provided by mathematics, simulation theory andcomputational biology. Young scientists in this areas are also invited to lecture from their perspective. Invited experts will review these areas in lectures. They will also meet the students for an additional twohours in a workshop discussion of basic concepts. Arbetsformer : Two seminars+worskhop every month for five months, 2,53 hrs on each occassion. Everyoccasion consists of a appr 12 hour seminar/lecture with the invited expert followed by a two hour opendiscussion, i.e 34 hours on each occassion. For each seminar the students will usually be given at least onearticle on the topic to read. Active participation in discussions in groups with invited speaker of highinternational standards is a key element. You also receive DVDrecordings of all lectures for further selfstudies at home. Examination : Continuous by workshop discussions. Written homeexam (essay). Obligatoriska moment : The seminars are compulsory. Absence can be compensated for after discussionwith the course leader.Antal studenter : 8 20Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : Lectures 12 times/month followed by discussion with the invited speaker, altogether3 hrs/occassion. Venue is one of the lecture halls at KI Campus, and discussiions at the seminar room A302 at MTC, Nobels väg 16, KI Campus, Solna.
Kursansvarig : Ingemar ErnbergInstitutionen för mikrobiologi, tumör och [email protected]
Box 280, Karolinska Institutet
17177Stockholm
Kontaktpersoner : Yvonne StrandbergInstitutionen för mikrobiologi, tumör och cellbiologi
Title : Pathology
Kursnummer : 2044Antal högskolepoäng : 3.0Datum : 20151019 20151030Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Laboratory MedicineSärskild behörighet : Kursens lärandemål : After the course the student should understand basic pathological events and beable to analyze the connection of these events to the development of diseases.Kursens innehåll : The course is divided into two parts. The first part illustrates cell injury, adaptation,tissue repair and inflammation. New methods in cellular and molecular pathology will be discussed. Duringthe second part of the course will focus on tumor development and malignancy. We will discuss how basicpathological responses to inflammation or injury might be the first steps on a multistep path tomalignancy.Arbetsformer : This is a full time course with lectures, seminars, demonstrations and microscopyexercises.Examination : Written examination.Obligatoriska moment : Demonstration/microscopy, microscopy practice, pathology "tour" and projectwork are compulsory. Absence must be compensated with a written report.Antal studenter : 16 30Urval av studenter : 1)Documented knowledge in areas such as human tissue biology, cell biology orphysiology (this kind of knowledge is a prerequisite to be able to benefit from the course). Those whoalready have studied pathology earlier (for example medical doctors) are not prioritized. 2)Date ofadmission to doctoral studies (those who have been admitted longest time ago have priority). Övrig information :
Kursansvarig : Barbro EkRylanderInstitutionen för laboratoriemedicin0858586444Barbro.Ek[email protected]
Kontaktpersoner : Arja KramsuInstitutionen för laboratoriemedicin
Barbro EkRylanderInstitutionen för laboratoriemedicin0858586444Barbro.Ek[email protected]
Title : Current Topics in Infection Biology
Kursnummer : 2074Antal högskolepoäng : 1.5Datum : 20150902 20151216Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Medicine, HuddingeSärskild behörighet : Kursens lärandemål : After the course, students should have increased their knowledge of various topicswithin the field of infection biology such as hostpathogen interactions including viruses, bacteria, parasitesetc, innate immune factors, signalling pathways, antigen presentation, generation of cellular and humoralimmune responses, as well as aspects of vaccine and antimicrobial treatment development. The goal isthat the students to be able to critically analyze data and concepts presented at the seminars within thecourse, and to discuss the data with the invited speakers. Since the lectures presented span over severalsubtopics all the students should also be able to gain new information on frontline research activitiesrelevant for their own research project and PhD studies.Kursens innehåll : The course is built up by a series of weekly seminars by invited speakers (internationaland national) presenting their current research in infection biology. The speakers will both give a basicintroduction to their field and present their own research and discuss that in the context of the field as awhole. The lectures will cover host/microbe interactions, routes and mechanisms of infection, thesusceptibility and the response of the host to such infections, and the molecular and physiological eventsleading to the clearance of microbes or a diseased state. Innate and adaptive immunity, inflammation, andthe biology of membranes and receptors will also be presented and discussions. Arbetsformer : The seminars are one hour long and are held weekly as part of a seminar series held. Atotal of 1520 seminars will be held during the semester.Examination : To ensure that the examination is at the individual level, each student is required to readthe review articles provided by each speaker and summarize and critically analyze one seminar in a writtenreport.Obligatoriska moment : Attendance at the seminars is compulsory to pass the course. If a student isunable to attend some seminars, she/he can compensate by summarizing and analyzing additionalseminars in a written report to make up for the absence.Antal studenter : 5 25Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : Seminars will be held on Wednesday 13.0014.00 at the Center for InfectiousMedicine, Department of Medicine, Karolinska Institutet, Karolinska University Hospital Huddinge.
Kursansvarig : Yenan BrycesonInstitutionen för medicin, [email protected]
Centrum för Infektionsmedicin, F59
14186Stockholm
Kontaktpersoner :
Title : Forskningsetik
Kursnummer : 2132Antal högskolepoäng : 1.5Datum : 20150825 20150915Språk : SvenskaNivå : ForskarnivåKursansvarig institution : Department for Clinical Science, Intervention and TechnologySärskild behörighet : Kursens lärandemål : Få en inblick i och förståelse av centrala forskningsetiska teorier, principer ochriktlinjer och därmed få möjlighet att reflektera över etiska aspekter av den egna forskningen. Målet ärockså att den forskarstuderande ska få en bättre förståelse av vad som är god vetenskap samt vargränserna går för vad som är etiskt oacceptabel forskning både vad gäller försök med människor och meddjur, samt vad som gäller för forskarens egen hederlighet. Kunskap och förståelse: Den forskarstuderandeska efter att ha gått kursen kunna 1. redogöra för forskningsetiska teorier, principer och till viss delriktlinjer, 2. visa kunskap angående vanliga forskningsetiska problemsituationer och de etiska verktygensom kan användas för att hantera forskningsetiska konflikter Färdigheter: Den forskarstuderande ska efteratt ha gått kursen kunna: 1. analysera forskningsetiska konflikter, 2. ge hållbara forskningsetiskaargument för eller mot ett förfarande Förhållningssätt: Den forskarstuderande ska efter att ha gått kursenha: 1. utvecklat ett forskningsetiskt förhållningssätt till andra forskarstuderande, handledare och senioraforskare, 2. förståelse för hur ett etiskt förhållningsätt uppfattas hos allmänheten Kursens innehåll : Att ge en introduktion till etiken i samband med forskning och en orientering om desstillämpning på problem inom det vetenskapliga området. Kursen behandlar bl.a. följande teman: centralaetiska principer, teorier och argument, forskningsetik/forskaretik, grundläggande värderingar och normerför god sed i forskningen, innehåll i och värdet av regelverk så som Helsingforsdeklarationen dess funktion,tillämpning, möjligheter och begränsingar, etikprövningar, avvikelser från värderingar, forskningsfusk ochvetenskaplig oredlighet. Det informerade samtyckets historia och komponenter. Försöksdjursetik,innefattande argument för och emot att använda olika djur för forskningsändamål samt de 3 R:en.Hantering av vetenskapligt författarskap (medförfattarskap, författarordning) och intressekonflikter iforskningen.Arbetsformer : Föreläsningar (ca 6t), gruppövningar, seminarier(ca 8t) och muntlig och skriftligpresentationExamination : Examination består av aktivt deltagande i seminarier, ett kortare skriftligt PM där ett temainom ramen för kursen behandlas. Detta PM presenteras också muntligt för de andra kursdeltagarna.Doktoranden förväntas relatera temat till det egna avhandlingsarbetet. Godkänd kurs innebär aktivtdeltagande i seminarier och godkänd muntlig och skriftlig presentation av examinationsuppgiften. Obligatoriska moment : Obligatoriskt är att delta vid introduktionstillfället och vid seminarier. Vidfrånvaro kan detta kompenseras med utökat PM skrivande och muntlig presentation för kursen ellerkursgivare.Antal studenter : 15 20Urval av studenter : Urvalet baseras på 1) kursplanens relevans för den sökandes doktorandprojekt(enligt motivering), 2) datum för doktorandregistrering (där tidigare registreringsdatum har förtur)Övrig information :
Kursansvarig : Sigridur KalmanInstitutionen för klinisk vetenskap, intervention och teknik08585 817 [email protected]
Kontaktpersoner : Carol MeltonInstitutionen för klinisk vetenskap, intervention och teknik
Title : Vetenskapsteori
Kursnummer : 2133Antal högskolepoäng : 4.5Datum : 20151006 20151201Språk : SvenskaNivå : ForskarnivåKursansvarig institution : Department for Clinical Science, Intervention and TechnologySärskild behörighet : Kursens lärandemål : Efter kursen skall kursdeltagaren ha en bred kunskap i vetenskapsteori samtförmågan att självständigt reflektera över och kritiskt diskutera vetenskapsteoretiska problem ivetenskapligt arbete, för både den egna forskningsuppgiften och forskning i allmänhet.Kursens innehåll : En introduktion till vetenskapsteorin och en förståelse för olika slag av vetenskapligtkunskapssökande. En grundläggande orientering om vetenskapsteoretiska frågor ges. Följande temanbehandlas: begreppet kunskap, vetenskap pseudovetenskap, hypoteser hypotesprövning, orsaker förklaringar, vetenskap ¿ värderingar samhälle.Arbetsformer : Föreläsningar (ca 12 t), gruppövningar, seminarier (ca 14 t) och muntlig och skriftligpresentation.Examination : Examination består av aktivt deltagande i seminarier, i ett skriftligt PM där ett tema inomramen för kursen fördjupas och behandlas mer utförligt, och genom att detta PM presenteras muntligt förde andra kursdeltagarna. Doktoranden förväntas relatera temat till det egna avhandlingsarbetet, alternativtandra (centrala) forskningsfrågor inom den egna disciplinen.Godkänd litteraturredovisning vid seminariersamt godkänd muntlig och skriftlig presentation av examinationsuppgift krävs för godkänd. Obligatoriska moment : Obligatoriskt är att delta vid introduktionstillfället och vid seminarier. Vidfrånvaro kan detta kompenseras med utökad muntlig och skriftlig presentation vid seminarium eller förkursgivaren.Antal studenter : 15 20Urval av studenter : Urvalet baseras på 1) kursplanens relevans för den sökandes doktorandprojekt(enligt motivering), 2) datum för doktorandregistrering (där tidigare registreringsdatum har förtur)Övrig information :
Kursansvarig : Sigridur KalmanInstitutionen för klinisk vetenskap, intervention och teknik08585 817 [email protected]
Kontaktpersoner : Carol MeltonInstitutionen för klinisk vetenskap, intervention och teknik
Title : Infectious Disease Epidemiology
Kursnummer : 2135Antal högskolepoäng : 1.5Datum : 20151012 20151016Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Medical Epidemiology and BiostatisticsSärskild behörighet : Knowledge in epidemiology and biostatistics equivalent to "Epidemiology I:Introduction to epidemiology" and "Biostatistics I: Introduction for epidemiologists", respectively, orcorresponding courses.Kursens lärandemål : Participants are expected to have a basic knowledge of epidemiological tools, andthe course aims to show how these tools apply to the study of infectious diseases. After successfullycompleting this course you as a student are expected to be able to: explain the concepts and terms usedin infectious disease epidemiology list the steps of an outbreak investigation describe the functions andproblems of a surveillance system design a simple model for an epidemic explain how population mixingpatterns influence epidemic spread design a study to test the effectiveness of a vaccine discuss theimportant determinants of the antimicrobial resistance problem discuss national and EU systems to controlinfectious diseases Learning outcomes are classified according to Bloom's taxonomy: knowledge,comprehension, application, analysis, synthesis, and evaluation. Kursens innehåll : Definitions; immunity; transmission routes; outbreaks; vaccinology; surveillance;models and mixing patterns; specific examples, such as antimicrobial resistance; control systems.Arbetsformer : Lectures, group discussions, computer simulations, case studies.Examination : To pass the course, the student has to show that the learning outcomes have beenachieved. Assessments methods used are group assignments along with written and oral individual tasks.Students who do not obtain a passing grade in the first examination will be offered a second examinationwithin two months of the final day of the course. Students who do not obtain a passing grade at the firsttwo examinations will be given top priority for admission the next time the course is offeredObligatoriska moment : Only the examination tasks are compulsory. Antal studenter : 12 25Urval av studenter : Selection will be based on 1) the relevance of the course for the applicant's project(according to written motivation), 2) date for registration as a doctoral student (priority given to earlierregistration date). Submit a completed application form and give all information requested, including ashort description of current research, motivation for attending and an account of previous courses.Övrig information :
Kursansvarig : Johan GieseckeInstitutionen för medicinsk epidemiologi och [email protected]
Kontaktpersoner : Gunilla Nilsson RoosInstitutionen för medicinsk epidemiologi och biostatistik08524 822 [email protected]
Title : To communicate science in different contexts
Kursnummer : 2144Antal högskolepoäng : 3.0Datum : 20150916 20151001Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Learning, Informatics, Management and EthicsSärskild behörighet : Kursens lärandemål : After the course the student is expected to be able to: 1. Orally present ownresearch adapted to different target groups. 2. Reflect on presentation skills and ability to adapt to differenttarget groups.Kursens innehåll : During the course each participant will be given the opportunity to develop practicaland theoretical knowledge in: Communication, perception and learning Presentation techniques Rhetoric Use of different media (such as Posters, Overheadprojector, PowerPoint, Whiteboard) Eachcourse participant will perform three oral presentations and receive feedback on content, presentation skillsand adaptation towards target group.Arbetsformer : The course design is based on reflective practice and includes selfdirected learning,lectures and literature seminar to process theoretical knowledge, and practical training in presentationskills.Examination : The assessment consists of two different tasks: 1. Reflective statement based inexperience, feedback and research/literature within communication and learning. 1. Oral presentation in apopular scientific context supported by PowerPoint or similar. To pass the course the participant needs toshow evidence that they reached the learning outcomes by fulfillment of the assessment criteria. Obligatoriska moment : Compulsory sessions are: 1. Oral presentation in a popular science context(video recorded) 2. Oral presentation in a scientific context and observe and give feedback to an oralpresentation made by a peer. Absence from the compulsory sessions or assessment seminar can becompensated through supplementary activity.Antal studenter : 20 40Urval av studenter : The selection for this basic general science course will be based on your admissiondate to doctoral education (priority given to earlier registration date). Please make sure that you haveentered the correct registration date for doctoral education in your personal profile. Övrig information : This is a two week course which requires time for independent work outside ofscheduled class time. Scheduled class room sessions are on the following dates: 1617 September, 2324September, 30 September and 1 October. The course is given in ENGLISH.
Kursansvarig : Cormac McgrathInstitutionen för lärande, informatik, management och etik
Kontaktpersoner : Ingrid SmedbergInstitutionen för lärande, informatik, management och etik08524 837 [email protected]
Title : Cardiovascular Epidemiology
Kursnummer : 2154Antal högskolepoäng : 1.5Datum : 20151019 20151023Språk : EngelskaNivå : Doctoral levelKursansvarig institution : The institute of Environmental MedicineSärskild behörighet : Kursens lärandemål : Students having successfully completed the course are expected to recognizedifferent risk factors or risk indicators for cardiovascular disease and different cardiovascular phenotypes.Students should be able to discuss the study designs most commonly used within cardiovascularepidemiology. In addition, students should be able to interpret study results critically.Kursens innehåll : Overview and discussion of risk factors/risk indicators environmental, genetic andbiochemical. Discussion of theories and concepts related to common epidemiological and genetic studydesigns cohort, casecontrol, and genetic association studies. Arbetsformer : Lectures (cathedral) Group work, to consolidate and reflect upon concepts introducedduring the course. Seminars. Examination : Learning outcomes will be assessed using 1) a short individual written examination coveringdifferent research methods used within cardiovascular epidemiology, and 2) a written group examination.Obligatoriska moment : Participation in group work and article seminars is mandatory. Compensationthrough an individual written assignment.Antal studenter : 12 25Urval av studenter : Eligible doctoral students will be prioritized according to 1) the relevance of thecourse for their research 2) the stated motivation for attending the course. We carefully consider yourmotivation to attend the course. There will be no selection based upon type of education and backgroundknowledge, however we will use this information to divide student in groups for the group works, so pleaseindicate it in your application.Övrig information : The course takes place at the Institute of Environmental Medicine (IMM), from 9 amtill 4 pm Monday to Friday. There will be lectures in the morning and group works in the afternoon.
Kursansvarig : Karin LeanderInstitutet för miljömedicin08[email protected]
Box 210 (Nobels väg 13), KI
171 77Stockholm
Kontaktpersoner : Ida Kettley CronfalkInstitutet för miljömedicin
Title : Basic Tumor Histopathology
Kursnummer : 2166Antal högskolepoäng : 1.5Datum : 20150914 20150925Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of OncologyPathologySärskild behörighet : Kursens lärandemål : At the end of the course the participants should be able to: Distinguish normalfrom malignant cells in tumor tissues and be acquainted with the morphology/histology of the differenttumor types, differentiation stage and tumor grade. Recognize cellular processes in the tumor tissue andits microenvironment like mitosis, cell proliferation, pleomorphism, lineage differentiation, tumor stage,necrosis, apoptosis, neural and vascular invasion, vascularisation. Understand ethical issues and legislationconcerning biobanking and practical issues on tumor handling.Kursens innehåll : Tumor histopathology and grading. Introduction. Endocrine tumors. Breast tumors. Prostate tumors. Gastrointestinal tumors. CNS tumors. Hematological malignancies. Sarcoma. Gynecologycal cancers. Tumor handling and biobanking.Arbetsformer : The first day will include an introductory lecture covering general aspects of tumormorphology/histopathology and grading. In the following days we will review one tumor diagnosis per dayorganized in 45 min introduction , followed by 2 hrs interactive microscopy sessions using a multiheadedmicroscope and a digital screen, guided by pathologists expert in each field. Home exercises consisting ondigital images of tumors together with the clinical history are given at least twice to the students fortraining. For distribution of files and examination we use KI Box.Examination : The students will get different case studies including digital images from tumors tissues andtheir clinical history via the KI Box account of the course. The students will then examine the cases andprovide a writen description of the relevant observations leading to a correct diagnosis and answers. Images and questions have been provided by each teaching pathologist. When appropriate, antiplagiarismtools will be used according to the guidelines from the Board of Doctoral Education at KI. Obligatoriska moment : 100% attendance is recommended, due that each session is exclusive andcannot be compensated for later on. The student will be asked to review the issue presented in case ofabsence in a session.Antal studenter : 7 17Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : The lectures take place at the lecture hall at Cancer Centrum Karolinska orRadiumhemmet. The microscopy session take place at the Division of Tumor Pathology, at Radiumhemmet.Entrance from CCK floor 2.
Kursansvarig : Bertha BrodinInstitutionen för onkologi[email protected]
Cancer Centrum Karolinska CCK R8:00
171 76Stockholm
Kontaktpersoner : Bertha BrodinInstitutionen för onkologi[email protected]
Title : Cellular and molecular infection biology
Kursnummer : 2176Antal högskolepoäng : 3.0Datum : 20151026 20151106Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Microbiology, Tumor and Cell BiologiSärskild behörighet : Kursens lärandemål : After the course the students will have an overview of the various aspects ofmicrobial infections with bacteria, viruses and parasites. The students will have knowledge on the level ofcurrent understanding of the cellular and molecular mechanisms used by pathogenic microbes, since thecourse will provide "stateoftheartlevel" presentations in selected aspects of a hostpathogen interaction.The students will be able to give examples of interdisciplinary studies in the research field of microbehostinteractions, many lectures focus on interdisciplinary themes such as microbecell interactions, microbialmanipulation of host inflammatory responses, pathogen transmission and novel techniques to studymicrobehost interactions. Analytical and critical thinking will be encouraged by the course design. Thestudents will also have an improved capability for scientific discussions, since the course provides thepossibility to interactive discussions with invited teachers, who will attend the student presentation. Afterthe course the students will have a more holistic picture of infection biology, and hopefully they will beencouraged to apply such new information for the benefit of their further graduate training and even getsignificant input for their own research. Kursens innehåll : Microbial pathogenesis, the interplay between microbes and various host responsesand transmission of pathogensArbetsformer : The course consists of lectures by inhouse and invited speakers on various topics in thediscipline of cellular and molecular infection biology. Presentations will cover basic aspects of the researchtopic that will provide the students with a foundation in the subject. In addition, the more advanced part ofthe lecture will present stateoftheart research. Groups of students will prepare a seminar and anothergroup will act as ¿opponents¿ to critically analyse the presentations. The students will subsequentlyparticipate in interactive studentdriven discussions which includes the invited teacher.Examination : The students will be assigned a series questions based on topics that have been discussedduring the course in a written examination.Obligatoriska moment : The compulsory parts of the course are preparation and attendance of thelectures and the student group presentations. If the students cannot attend a lecture they should write asummary based on the course literature for this lecture. There will be a written examination at the endwhere the students should discuss a given problem within microbial pathogenesis and microbehostinteractions.Antal studenter : 10 40Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : The course will be held at the Department of Microbiology, Tumor and Cell Biology(MTC). It will include lectures from International, National and local researchers in the fields of Bacteriology,Virology and Parasitology.
Kursansvarig : Keira MelicanInstitutionen för neurovetenskap
Kontaktpersoner : Benjamin LibbertonInstitutionen för neurovetenskap
Gerald McInerneyInstitutionen för mikrobiologi, tumör och cellbiologi08 [email protected]
Title : How to make genetically modified mice for immunologicalresearch
Kursnummer : 2186Antal högskolepoäng : 1.5Datum : 20150907 20150911Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Medicine, SolnaSärskild behörighet : Kursens lärandemål : After taking the course the student should have an in depth knowledge of how tomake genetically modified mice. In summary, the student will aquire enough practical and theoreticalknowledge to allow them to independently make genetically modified mice. Specifically, the student willknow how to design and make DNA constructs for gene targeting and transgenesis, how to design andperform genotyping using Southern blotting and PCR, and finally how to use the modified mice inimmunological experiments. Furthermore, after the course the students will know how to critically analyseexperiments presented in the scientific literature and judge their scientific quality. Kursens innehåll : 1) Gene targeting and transgenesis in general: a) a short history of gene targeting andtransgenesis in mice, b) when is gene targeting or transgenesis suitable for immunological experiments?, c)overview of the work process. 2) Designing and making constructs for gene targeting and transgenesis. a)how to obtain the necessary information for designing a gene targeting construct, b) different approachesto make DNA constructs for gene targeting and transgenesis 3) Conditional gene targeting. 4) Commonproblems in gene targeting and transgenesis, and how to solve them. 5) How to use genetically modifiedmice in immunological research Arbetsformer : Lectures will be the main form of teaching during the course. However, a workshop and ahomework assignement will also be part of the course. In groups of three, the students will design a genetargeting project from start to finish and present their research plan.Examination : Active participation in the workshop and the scientific quality of the homework assignementwill be the main criteria for the examination of the students.Obligatoriska moment : The homework assignement is compulsory. The homework can alternatively behanded in later in written form.Antal studenter : 12 16Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information :
Kursansvarig : Alexander EspinosaInstitutionen för medicin, Solna
Kontaktpersoner : Lisa WesterbergInstitutionen för mikrobiologi, tumör och cellbiologi
Alexander EspinosaInstitutionen för medicin, Solna
Title : Developmental biology for regenerative medicine
Kursnummer : 2188Antal högskolepoäng : 3.0Datum : 20150831 20150911Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Cell and Molecular BiologySärskild behörighet : Kursens lärandemål : After the course, the students should know the basics of stem cell biology and themedical use of cell therapy. The students should be able to describe and understand the theoretical basisfor key technologies utilized in stem cell research.Kursens innehåll : The course covers key concepts in translational research from the laboratory to theclinic, including an advanced review of descriptive and molecular developmental biology.Arbetsformer : The pedagogic learning activities on the course consist of cathedral lectures, groupdiscussions and student presentations.Examination : The students are examinated individually with a quiz or a written essay. The final courseexamination is a project presentation in groups.Obligatoriska moment : Participation in the group discussions and student presentations is mandatory.Compensation through an individual written assignment.Antal studenter : 5 8Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : The course is organized by the Research School of the Linné Center DBRM(Developmental Biology for Regenerative Medicine). More course information can be found at the ResearchSchool web pages at www.dbrm.se. The course is full time and the course venue is the seminar room A216at CMB, Berzeliusv 35.
Kursansvarig : Matti NikkolaInstitutionen för cell och molekylärbiologi
Kontaktpersoner :
Title : Live cell imaging
Kursnummer : 2283Antal högskolepoäng : 3.0Datum : 20151005 20151016Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Cell and Molecular BiologySärskild behörighet : noneKursens lärandemål : After passing the completed course, the students will be familiar with the basicprinciples of fluorescence microscopy and diverse live cell imaging techniques. They will be competent inindependently designing and performing live cell imaging experiments and understand thepossibilities/limitations of different live cell imaging techniques.Kursens innehåll : Basic principles of fluorescence microscopy and live cell imaging. Confocal LaserScanning Microscopy Deconvolution fluorescence Microscopy Basic principles of advanced fluorescencetechniques. Design and perform live cell imaging experiments. Data analysis and presentation. Arbetsformer : The pedagogic learning activities on the course consist of lectures, research seminars,laboratory work (imaging), group discussions, data processing and student presentations.Examination : The students are examinated through 1) an individually written assigment (case study), 2)a practical session and 3) a poster presentation. Obligatoriska moment : All activities (lectures, research seminars, laboratory work, group discussions,data processing and student presentations) are compulsory. If students are unable to attend they have todiscuss with course organizer how this can be compensated. Compensation of the laboratory work is notpossible.Antal studenter : 8 16Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : The course will cover theoretical and practical work on different fluorescencemicroscopes (confocal laser scanning microscopy, deconvolution fluorescence microscopy, grid confocalmicroscope) focused on live cell imaging with the application of various fluorescence techniques(Fluorescence Restoration After Photobleaching, Fluorescence Loss Induced by Photobleaching,photoactivation, fluorescence resonance energy transfer). The course includes introduction lectures, 23research seminars from international speakers, and handson sessions at different fluorescencemicroscopes.
Kursansvarig : Matti NikkolaInstitutionen för cell och molekylärbiologi
Kontaktpersoner :
Title : Clinical achievements of reproductive medicine
Kursnummer : 2291Antal högskolepoäng : 1.5Datum : 20150921 20150925Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department for Clinical Science, Intervention and TechnologySärskild behörighet : Kursens lärandemål : The objectives of this course are that at the conclusion of this course studentsshould be able to have a comprehensive view of: The key factors involved in gamete biology, gametephysiology and in vivo and in vitro fertilization The key factors involved in early embryo development andimplantation The clinical achievements of modern reproductive medicine and Assisted ReproductionTechniques (ART) The causes of subfertility and infertility and the current therapeutic approaches The linkbetween genetics and male/female infertility and the implications in ART The difference betweenchromosomal and DNAbased genetic disease and the different technologies to detect them The basicgenetic technology used in Preimplantation Genetic Diagnosis (PGD) The in vitro systems, culture systemsand work stations used in ART The influence of the laboratory and clinic environment on embryo culture The assessment of developmental potential and the morphological aspect of normal oocytes, zygotes,cleavage stage embryos, morulae and blastocysts The implantation process The pathophysiology ofrepeated early pregnancy loss and ectopic pregnancy The general aspects, implication and clinicalapplications of stem cells research The novel development of ART for fertility preservation, cryobiologyand transplantation The epigenetic aspects of assisted reproduction Kursens innehåll : Contents: Biology of the gametes, fertilization and early embryo development Normaland pathological implantation, early pregnancy loss, ectopic pregnancy, repeated miscarriage In vitrospermatogenesis and oocyte maturation Clinical investigation and therapeutic approach on female andmale infertility Genetics in infertility Gonadal dysgenesia Stem cells research Assisted reproductiontechniques (ART) In vitro systems and cultures Cloning. Somatic cell nuclear transfer Clinical aspects offertility preservation Cryobiology systems for fertility preservation Preimplantation genetic diagnosis Epigenetics in assisted reproduction Experimental reproductive tissue transplantation procedures: ovarianand testicular tissue transplantation transplantation of the uterus Arbetsformer : lectures, seminaries/discussion and laboratory demonstrations Examination : Written examination and discussion Obligatoriska moment : All teaching activities, the laboratory sessions and the lectures are obligatory. Incase of not attendance to the activities, students should produce a literature work related with the subjectof the missing activity.Antal studenter : 6 12Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : The course is oneweek fulltime and includes laboratory demonstration and visits tothe reproductive medicine clinics at Karolinska Unversity Hospital, Huddinge. Speakers are internationalauthorities in clinical and experimental research in reproductive medicine
Kursansvarig : Kenny RodriguezwallbergInstitutionen för onkologipatologi0858580000kenny.rodriguez[email protected]
ReproduktionsmedicinKarolinska Universitetssjukhuset Huddinge141 86Stockholm
Kontaktpersoner : Kenny RodriguezwallbergInstitutionen för onkologipatologi0858580000kenny.rodriguez[email protected]
ReproduktionsmedicinKarolinska Universitetssjukhuset Huddinge
141 86Stockholm
Jose InzunzaInstitutionen för biovetenskaper och näringslära08585 850 [email protected]
Hälsovägen 7, Novum
141 86Stockholm
Title : Basic immunology
Kursnummer : 2302Antal högskolepoäng : 3.0Datum : 20150915 20151029Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Medicine, SolnaSärskild behörighet : Kursens lärandemål : To understand basic principles of innate and adaptive immunity and how differentcomponents of the immune system cooperate. To be able to relate, compare and understand experimentalaspects of immunerelated disease in a clinical perspective. To adapt knowledge gained of the function ofthe immune system by being able to analyze and discuss an immunological/clinical case (group project). To present the group project and discuss the results as well as work in pairs with clinical cases.Kursens innehåll : The course is separated into two parts. In part 1 we discuss basic immunologicalmechanisms within the innate and adaptive immune response. In part 2 we apply the knowledge in clinicalsettings such as defence against infection, autoimmune and allergic disease or transplantation. Part 1: Introduction An overview of the immune system T cells B cells Antigenpresenting cells Innate vsadaptive immune responses Methods to study immune reactions. Part 2: Immune defence againstbacterial and viral infections Primary immunodeficiencies Autoimmune disease Allergy Vaccination Clinical Immunology Transplantation Tumour Immunology Questions and discussions Presentation ofprojects. Arbetsformer : The course is given fulltime during a total of six days separated into two parts. Theteaching is mainly in lecture/seminar form but also includes project work studying cases individually andpairwise, as well as in small groups. The group projects are then presented orally on the last day of thecourse. The project work requires studies between the two course parts, including meetings with mentors.Course literature (Abbas) and cases are handed out at the course start. An immunological quiz is connectedto the different chapters in the book so that the student will be able to digest the relatively big material. The course is designed so that clinically active doctors will be better able to combine it with work in theclinic (Mondays and Fridays contain no scheduled course work) .The purpose of dividing the course into twoparts is that the participants should have time to thoroughly study the literature from part 1 (fundamentalimmunological mechanisms) before teaching of the applied immunology in part 2 starts. Considering thesubstantial literature requirement plus the cases and project work, we estimate that an extra 32h of studyis needed, which is not included in the schedule. Examination : Webbased exam on the course content. Oral presentations of smallgroup project work. Atthis occasion special attention is given to that all students are actively participating. The clinical cases areexamined by written reports. Obligatoriska moment : Project work and attendance at the project presentation is compulsory as well aswork with two clinical cases. In the case of absence a separate occasion is organized with presentation forthe course organizers. The webbased exam is mandatory. Antal studenter : 12 45Urval av studenter : Selection of students is based on 1. Date of registration as doctoral student2.Motivation to attend the course.Övrig information : The course is divided into two parts, consisting of three days each (Tuesday toThursday 1517 September and 2729 October). Between the two parts the participants perform projectwork, including meetings with mentors as well as study the literature. Teachers include specialists indifferent fields of immunology including both basic and clinical researchers: examples: Peter Bergman, OlaWinqvist, Rolf Kiessling, Helena Erlandsson Harris and Guro Gafvelin. Litterature includes Abbas (BasicImmunology) the book is free and is handed out at the course start and clinical cases as well ashandouts etc. The course location is at or near the Center for Molecular Medicine (CMM), KarolinskaUniversity Hospital in Solna.
Kursansvarig : Jan WahlstromInstitutionen för medicin, Solna08[email protected]
Lungforskningslab L4:01Karolinska Universitetssjukhuset, Solna171 76Stockholm
Title : Functional Fluorescence Microscopy Imaging (fFMI) inbiomedical research
Kursnummer : 2348Antal högskolepoäng : 3.0Datum : 20151102 20151113Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Clinical NeuroscienceSärskild behörighet : Kursens lärandemål : At the end of the course the student should be able: 1. to use fundamental aspectsof molecular structure to describe molecule (matter) interaction with light (electromagnetic radiation) andthe emission of fluorescence, and to use this knowledge to discuss fluorescent properties of a fluorophoreand different labeling strategies. 2. to understand the fluorescence imaging instrumentation, to defineelements of a fluorescent microscope and to describe instrumentation properties in terms of sensitivity. 3.to describe the theoretical background behind fluorescence based methodologies for studying molecularinteractions in live cells. Discuss pros and contras in relation to the biological problem studied. 4. to specifyinstrumental requirements and to design a fluorescence imaging assay for a biological problem of interest. 5. to apply a specific labeling strategy and perform a live cell fluorescence imaging assay. 6. to documentexperimental work in accordance with Good Laboratory Practice (GLP) guidelines. 7. to communicate theresults in written and oral form. 8. to discuss the adequateness of the methodology used in the scientificliterature concerned. Kursens innehåll : Fluorescence microscopy and associated techniques are becoming indispensableresearch tools for investigating molecular mechanisms of biological processes. Versatility of fluorescencebased methodologies comes from the multifaceted possibility to characterize fluorescence emission byposition, intensity, wavelength, lifetime and polarization. These methodologies bring new biological insightat an unprecedented rate and are of crucial importance for the development of life sciences. The coursecovers the following topics: Luminescence and the nature of light (Fluorescence, Phosphorescence, Lightscattering, RayleighTyndall scattering, Raman scattering); Fluorescent markers and their photophysicalproperties (Organic fluorescent dyes for covalent conjugation (Rhodamine 6G, Alexa dyes, Cyanine dyes);Quantum dots; Intrinsically Fluorescent Proteins (Aequorea victoria (GFP, YFP), Discosoma coral (DsRFP)and Montipora (Keima) families); Selectively binding and intercalating dyes (DiI, DraQ 5). Labelingstrategies for biomedical application. Instrumentation for fluorescence imaging (Light sources, Wavelengthselection, Detectors, Readout devices, Sample holders, Problems of high blank values, Cuvettes, Solventsand Reagents, Other contaminants); Quantitation and Sensitivity (Instrumental sensitivity, Methodsensitivity, Absolute sensitivity); Factors affecting quantitative accuracy (Adsorption, Photodecomposition,Oxidation, Temperature, pH, Innerfilter effects, Quenching); Fluorescence based methodologies forstudying molecular interactions in live cells (FRET, FLIM, FRAP). Singlemolecule detection (QuantitativeAPD imaging, FCS and FCCS). Nonlinear microscopy (Multiphoton excitation, STED). Spatially resolvedfluorescence imaging (STORM, PALM). Arbetsformer : The course includes lectures, laboratory sessions, discussion sessions and a project work.Examination : The final assignment consists of a written project report (5 pages) and an oral presentationof the project report (15 min). Obligatoriska moment : All sessions are compulsory. Please report any absence to the course leader inadvance by email. Absence from any part of the course (lectures, laboratory sessions, discussion sessionsand exam) is generally not accepted but could in special cases be compensated by an individually tailoredadditional module and a special written examination organized by the course committee.Antal studenter : 8 12Urval av studenter : This course is on advanced fluorescence microscopy imaging and spectroscopytechniques for quantitative study of molecular transport and interactions in live cells. Number ofparticipants is limited to 12. Priority will be given to applicants who can concisely (max 250 words) show intheir application an urgent need to begin their independent work with these techniques. Övrig information : This is a two week course, with 10 sessions. Each session includes a lecture (1 h),laboratory practice and discussions (3 h) and time for selfstudy. Last session is reserved for assessment.<br /> The total working load for the students is estimated to be 95 h (3 hp).<br /> Experimentalexercises are carried out in the fFMI laboratory CMM, L5:02, 020a.<br /> Lectures are conducted in thelecturing hall CMM L8:01, 021.
Kursansvarig : Vladana VukojevicInstitutionen för klinisk [email protected]
CMM L8:01
17176Stockholm
Kontaktpersoner :
Title : Survey of Molecular Endocrinology
Kursnummer : 2381Antal högskolepoäng : 3.0Datum : 20150928 20151009Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Medicine, HuddingeSärskild behörighet : Kursens lärandemål : After successfully completing this course, student should have obtained afundamental knowledge of molecular endocrinology and acquired the following abilities: 1. explain themolecular mechanisms by which peptide and steroid hormones activate their receptors to provoke theirbiological effects 2. comprehend how the actions of hormones are involved in diseases 3. constructpathways of the endocrine systems that link control and production of hormones in specific tissues with theactions of these hormones in their respective target organs 4. analyse and evaluate scientific reports withinthe research field of molecular endocrinology 5. develop an indepth comprehensive knowledge ofendocrinology from a physiological, cellular, and molecular perspective 6. incorporate knowledge learnedfrom this course to critically evaluated clinical and research case problems relating to molecularendocrinology mechanisms 7. evaluate clinical, translational and basic research articles critically andconceptualize alternative interpretations approaches and theories from primary molecular endocrineprinciples learned in the course 8. structure principles endocrine concept proposal in hypothesis drivenobjectives for a research grant 9. prepare for public speaking infront of a scientific audience Kursens innehåll : This course will cover current topics involved in hormone signalling at a cellular andmolecular level from receptor interaction to gene response including receptor structure and functioninteractions with their hormone, second messengers, transcription regulation and autocrine and paracrinefeedback signalling pathways. The course will emphasize the critical understanding of how hormones actat the molecular level and why their signalling pathways synergize or antagonize each other under normaland pathological physiological conditions. A survey of current topics in endocrinology will be used toexemplify the concepts of the course such as stem cell commitment and differentiation, the molecularsignalling and genetics of embryogenesis; reproductive determination and differentiation; cancer stem celldedifferentiation and carcinogenesis; hormonal regulation of gene expression, steroid and peptide hormoneaction via paracrine, autocrine signalling; endocrine mechanisms of receptor interaction, transmembraneand intracellular signal transduction, ionic signalling, and regulation of nuclear gene transcription. Arbetsformer : The course will consist of cathedralstyle lectures to exposure students to fundamentalmolecular endocrine concepts, current topic seminars to exemplify concepts, and studentled seminars anddiscussions to allow the students an opportunity to utilize conceptual knowledge within an informalenvironment. Examination : 1. One studentled presentation and discussion with chosen student partner Teams of twostudents each will be assigned a current journal article with an emphasis in molecular endocrinology topresent to the rest of the class. All articles will be read by the students prior to the presentation. Each teamwill be assigned a faculty member who will supervise their preparation and understanding of the article tobe presented at an assigned date during class. Each team will make a formal presentation on the article andwill review, critique and discuss alternative interpretations of the article. (Learning outcomes 4, 6, 7, and 9) 2. one written peer evaluation report Each student will be assigned one team led presentation to critiqueboth presenters and journal article. The critique will be formulated in a grant style format. The student willbe expected to review the specific topic within molecular endocrinology that the article emphasizes. Thencreate a testable question and develop a hypothesis based on the topic. Then develop a methodologicalapproach to prove the hypothesis. The student teams that present the article will be considered experts inthat topic and the student will critique their position with in the field. (Learning outcomes 4, 6, 7, and 8) 3.one final exam The final written exam will assess the fundimental principles in the following learningoutcomes 1, 2, 3, and 5. Obligatoriska moment : The students are expected to attend all lectures and seminars. They areexpected to actively participate in discussions. Missed sessions may be replaced by written tasks adapted tothe situation. Antal studenter : 5 25Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : This course will be located on the Solna campus. During lecture days, lectures will beheld between 1014.
Kursansvarig : John Flanagan
Institutionen för [email protected]
CMM, L8:01Andrology and Molecular Endocrinology Units171 76 Solna
Kontaktpersoner :
Title : Aktuell Omvårdnadsvetenskap teori och praxis
Kursnummer : 2407Antal högskolepoäng : 4.5Datum : 20151002 20151120Språk : SvenskaNivå : ForskarnivåKursansvarig institution : Department of Neurobiology, Care Sciences and SocietySärskild behörighet : Tidigare studier inom vårdområdet och närliggande områden i förhållande tillforskningsprojektets inriktning.Kursens lärandemål : Kursen syftar till fördjupning i omvårdnadsämnets begreppsliga och teoretiskagrunder, samt granskning och värdering av aktuell omvårdnadsvetenskaplig forskning. Mål för lärande ärstuderandes tillägnan av omvårdnadsvetenskaplig begrepps och teorigrund samt pågåendeomvårdnadsvetenskapliga paradigm och diskurser. Studerande ska kunna ställa sammanvetenskapteoretiska grunder för teori och begreppsutveckling inom omvårdnad samt kunna tillämpa detta irelation till egen forskningsinriktning. Studerande ska kunna förklara den historiska utvecklingen avomvårdnad som vetenskap och kunna sammanfatta för innehållet i utvalda omvårdnadsteorier Studerandeska kunna kritiskt granska, analysera och värdera utvecklingen av omvårdnadsvetenskapliga begrepprelaterat till egen forskningsinriktning. Kursens innehåll : Vetenskapsteoretiska aspekter på omvårdnadsvetenskap Teoriutveckling ochbegreppsutveckling inom en vetenskap Metateoretiskt perspektiv enligt Meleis Den Nordiska utvecklingenav omvårdnad/vårdvetenskap Granskning och värdering av aktuell omvårdnadsforskning samt pågåendeteoriutveckling Arbetsformer : Målen bearbetas genom att studera internationell och Nordisk utveckling avomvårdnadsvetenskap. Exempel studeras på olika forskningsprogram inom omvårdnad vårdvetenskap. Vibekantar oss med, analyserar och granskar kritiskt, paradigmutvecklingen inom ämnet idag. Kursen byggerpå en huvuddel av självstudier av litteratur. Arbetsformerna på campus är seminarier samt föreläsningar. Examination : Litteraturuppgifter på obligatorisk kurslitteratur samt integrativ granskning och analys avomvårdnadsteoretiska grundbegrepp i relation till eget projekt. Obligatoriska moment : Undervisningsmomenten på campus, föreläsningar och seminarier under kursenär obligatoriska. Frånvaro kompenseras genom skriftliga eller muntliga extrauppgifter vilka beslutas avexaminator. Antal studenter : 15 30Urval av studenter : Urvalet baseras på 1) kursplanens relevans för den sökandes doktorandprojekt(enligt motivering), 2) datum för doktorandregistrering (där tidigare registreringsdatum har förtur)Övrig information : HT 2015 kommer fredagarna 2/10, 16/10, 6/11 och 20/11 vara obligatoriska campussamlingar för kursen. Kursen ges på Alfred Nobels Alle 23 i Huddinge (tågstation Flemingsberg).
Kursansvarig : Maria Arman Institutionen för neurobiologi, vårdvetenskap och samhä[email protected]
Kontaktpersoner :
Title : Causal Inference for Epidemiological Research
Kursnummer : 2416Antal högskolepoäng : 1.5Datum : 20151130 20151204Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Medical Epidemiology and BiostatisticsSärskild behörighet : The students are expected to have taken Epidemiology I, Epidemiology II,Biostatistics I, and Biostatistics II. Exceptions can be made if the students have taken other courses with anequivalent content.Kursens lärandemål : After the course the student will be able to use counterfactuals to express andinterpret causal queries be able to judge when standard statistical methodology is appropriate for causalinference, and when it is not be able to use Directed Acyclic Graphs to describe and analyze complexepidemiological scenarios be able to use Marginal Structural Models to analyze longitudinal data, withadditional help from a skilled statistician Kursens innehåll : Causal inference from observational data is a key task of biostatistics and of alliedsciences such as sociology, education, behavioral sciences, demography, economics, health servicesresearch, etc. These disciplines share a methodological framework for causal inference that has beendeveloped over the last decades. This course presents this unifying causal theory and shows howbiostatistical concepts and methods can be understood within this general framework. The courseemphasizes conceptualization but also introduces statistical models and methods for timevaryingexposures. Specifically, this course strives to a) formally define causal concepts such as causal effect andconfounding, b) identify the conditions required to estimate causal effects, and c) use analytical methodsthat, under those conditions, provide estimates that can be endowed with a causal interpretation. The(causal) methods can be used under less restrictive conditions than the traditional statistical methods. Forexample, causal methods allow one to estimate the causal effect of a timevarying exposure in the presenceof timedependent confounders that lie on the causal pathway between exposure and outcome.Arbetsformer : Lectures and group discussions.Examination : There will be a takehome exam handed out at the last day of the course. Students who failwill be given the opportunity to write at a maximum 2 reexams. Dates for the reexams will be announcedlater.Obligatoriska moment : Antal studenter : 12 25Urval av studenter : Eligible doctoral students will be prioritized according to 1) the relevance of thecourse syllabus for the applicant's doctoral project (according to written motivation), 2) date for registrationas a doctoral student (priority given to earlier registration date). To be considered, submit a completedapplication form. Give all information requested, including a short description of current research andmotivation for attending, as well as an account of previous courses taken. Övrig information : Prerequisite knowledge equivalent to "Epidemiology I: Introduction to epidemiology","Epidemiology II: Design of epidemiological studies", "Biostatistics I: Introduction for epidemiologists" and"Biostatistics II: Logistic regression for epidemiologists" or courses with corresponding learning outcomes
Kursansvarig : Yudi PawitanInstitutionen för medicinsk epidemiologi och biostatistik
Kontaktpersoner : Gunilla Nilsson RoosInstitutionen för medicinsk epidemiologi och biostatistik08524 822 [email protected]
Title : Methods in molecular biology and their applications inmedical research
Kursnummer : 2418Antal högskolepoäng : 3.0Datum : 20150907 20150918Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Laboratory MedicineSärskild behörighet : Kursens lärandemål : After the course, the students will understand the principles, from both atheoretical and practical viewpoint, of a number of basic techniques used in DNA/protein research and theirapplication in medical research. The students should also be able to design and perform investigations withsome of the discussed techniques.Kursens innehåll : The aim of this course is to confer knowledge of how basic molecular biology andprotein work can be applied in clinically oriented research work. The course is designed for graduatestudents with limited experience of molecular biology and combines a lecture program with laboratory work.The lectures will include theoretical and practical aspects on basic concepts concerning techniques inmolecular biology and proteomics and their application in medical research. Specified subjects will includecloning, RNAanalysis, promoter studies, DNAsequencing, expression, bioinformatics, antibody basedprotein detection and proteomics. The overall objective is to convey knowledge of possibilities andlimitations with different techniques and introduce valuable methodology for the students PhDprojects. Arbetsformer : The course combines a lecture program in the morning with laboratory work in theafternoon, where course participants will be subdivided into smaller groups.Examination : The students will be asked to solve a scientific problem using methods they learned duringthe course. The last day of the course, the participants will give a presentation. They should be able todefend the laboratory design, discuss methodologies applied and anticipated results. The students will workin pairs. The task will be given to the participants at the end of the first week.Obligatoriska moment : Laboratory work is compulsory. To compensate for absence, selfstudies and anwritten essay on the topic(s) that they have missed must be performed.Antal studenter : 8 14Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : The course combines a lecture program in the morning with laboratory work in theafternoon, where course participants will be subdivided into smaller groups.
Kursansvarig : Agne KulyteInstitutionen för medicin, Huddinge
Kontaktpersoner : Camilla PramfalkInstitutionen för laboratoriemedicin
Title : Principles of nucleic acid structure
Kursnummer : 2430Antal högskolepoäng : 4.5Datum : 20151116 20151204Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Biosciences and NutritionSärskild behörighet : Kursens lärandemål : After the course, the participants will be able: to describe and to visualize nucleicacid structures. to apply principles regulating nucleic acid structures. to explain the relation betweenstructure and function in nucleic acid molecules to evaluate critically experiments used to provide RNA orDNA structural information. Kursens innehåll : A general introduction to nucleic acids nomenclature. Structural and conformationalfeatures of nucleotides. Physical properties. Hydrogen bonding and base stacking. Water and nucleic acid.Metal ion and nucleic acid. Secondary and tertiary structures of DNA and RNA. Methods to determinestructures and dynamics of DNA and RNA systems (such as xray crystallography, NMR, theoreticalapproaches and so on) General consideration on proteinnucleic acid interactions, DNA superhelix, higherorder nucleic acid structure. Small introduction to secondary structure predictions, structural database,molecular visualization. Three invited lectures on specific topic.Arbetsformer : The course consist in lectures, seminars, short presentations given by the participants.group activities under the supervision of the course leader, computer tutorials on database and molecularvisualization (14 meetings of three hours each) During the course period, the participants will workindividually on an written assessment portfolio, give and receive feedback on the written work. In addition,the participants will prepare and discuss a seminar on an assigned topic. The participants should integrateeach lectures hour with homework and reading. Examination : A final written exam will be used to assess the participant's ability to describe and apply thestructural principles of nucleic acid structures. The seminar and written assessment portfolio will be used toassess the participant's ability to explain the relation between structure and function in nucleic acidmolecules and to evaluate critically experiments used to provide RNA or DNA structural information. Obligatoriska moment : The participant must participate actively by attending the lectures and theseminars, by completing the assigned tasks. In addition, the participant must complete the assessmentportfolio and final exam. Absence to a lecture will be compensated with extra assignments. The studentswill get some key questions on the corresponding lecture, and the answers should be submit in written formfor review and approval. Antal studenter : 8 20Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : The course is held at Huddinge Campus. The meetings will be held from 9 to 16during all the day of week 47, and Thursday and Friday of weeks 48 and 49. A minisymposium will be heldon Friday 27th November with national and international experts (seehttp://www.biosci.ki.se/users/villa/teach.htm for the speakers in the previous occasions). The course isheld every 1.52 years
Kursansvarig : Alessandra VillaInstitutionen för biovetenskaper och näringslära+468[email protected]
Hälsovägen 7NOVUM141 83Huddingen
Kontaktpersoner :
Title : Clinical Research in Lipid Metabolism
Kursnummer : 2433Antal högskolepoäng : 1.5Datum : 20151019 20151023Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Medicine, HuddingeSärskild behörighet : Kursens lärandemål : After the course the students will be able to: 1. Describe lipid and lipoproteinmetabolism 2. Understand how to analyze fatty acids, and sterols (by SEC, HPLC and gaschromatographymass spectrometry) 3. Understand principles for subcellular fractionation, enzyme and receptor assays, andmolecular biology of proteins in lipid metabolism 4. Describe genetic hyperlipoproteinemias 5. Understandwhich techniques that can be used in in vivo studies, such as biopsy techniques, microdialysis, and inturnover studies of lipid and lipoprotein metabolismKursens innehåll : Overview and new developments within the field of clinical research in lipidmetabolism. Emphasis will be laid on cholesterol metabolism, lipoproteins, lipoprotein receptors and on theregulation of enzymes involved in biosynthesis and metabolism of cholesterol, bile acids, fatty acids andtriglycerides. Genetic diseases and effects of diet on clinical conditions such as atherosclerosis, obesity,diabetes, and gallstone disease will also be highlighted. Arbetsformer : Lectures (24). The participants will also be invited to present their own projects for generaldiscussion on the methodological aspects of their project. Examination : In order to evaluate the students knowledge regarding clinical research in lipid metabolisma written examination consisting of short answer questions and multiple choice questions will be given. Obligatoriska moment : The lectures are not mandatory. However all information presented at thelectures is compulsory and will be a significant basis for the written examination. Antal studenter : 10 30Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant¿sdoctoral project (according to written motivation) and 2) date for registration as a doctoral student (prioritygiven to earlier registration date).Övrig information : The course is held in English and lectures and self studies will correspond to 40working hours (1.5 ECTS credits). The location is the Red Seminar Room at Novum, Karolinska Institutet,Huddinge
Kursansvarig : Mats RudlingInstitutionen för medicin, Huddinge
Kontaktpersoner : Sara StranieroInstitutionen för medicin, Huddinge
Ylva BondeInstitutionen för medicin, Huddinge
Lena EmtestamInstitutionen för medicin, Huddinge
Title : Public health intervention and implementation research
Kursnummer : 2454Antal högskolepoäng : 7.5Datum : 20151019 20151120Språk : EngelskaNivå : Doctoral levelKursansvarig institution : The institute of Environmental MedicineSärskild behörighet : Kursens lärandemål : At the end of the course the student should be able to: 1. Define core concepts inintervention and implementation research 2. Understand the concept of evidencebased public health 3.Understand how to critically appraise published intervention and implementation studies, as well assystematic reviews in public health 4. Describe models and frameworks of intervention and implementationresearch 5. Design an intervention study, which includes a relevant problem theory and a programmetheory, appraisal of ethical aspects as well as evaluation design 6. Design the implementation of anevidencebased programme or practice, and describe the evaluation design 7. Understand concepts offidelity and adaptation Kursens innehåll : As this course aims at giving doctoral students knowledge in theory, method andpractice in the field of public health intervention and implementation research, the content focuses on thefollowing themes: 1. Models and frameworks in intervention and implementation research 2. How to apply atheoretical perspective using relevant change theories 3. Intervention and implementation corecomponents, barriers and facilitators 4. Appropriate study designs for process and outcome evaluation 5.Systematic and critical appraisal of published intervention and implementation studies 6. Dissemination ofscientific results Arbetsformer : The course is based on lectures in combination with seminars in order to promote areflective, analytical and critical approach towards this research field. The course will also use groupassignments and group discussions to promote the students active participation in their learning process, aswell as the ability to accomplish tasks both individually and in groups. All teaching activities aim atenhancing the student's ability to apply for example core concepts and theoretical frameworks, not the leastethical aspects, in an analytical and reflective practice and to apply this on the students own researchprojects. All teachers in the course are active researchers in the field of intervention and implementationresearch. Examination : The students' knowledge and skills in theory, method and practice in the field of publichealth interventions and implementation research will be assessed in relation to the expected learningoutcomes through the following examinations: a. Formative assessment during active participation inseminars with presentations, in discussions and short seminar reports b. Summative assessment of awritten project report, oral presentation of the report and opposition Obligatoriska moment : Participation in scheduled seminars and group work and examination iscompulsory. Absence is compensated through a written summary of the literature for the seminar wherethe absence occurred. Antal studenter : 12 20Urval av studenter : Selection will be based on the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation)Övrig information : Classroom meetings are scheduled on Mondays and Tuesdays. All teachers involved inthe course are active researchers in the field of intervention and implementation research.
Kursansvarig : Lydia KwakInstitutet för miljömedicin
Kontaktpersoner : Johanna BergmanInstitutet för miljömedicin
Nobels väg 13
17177Stockholm
Title : Thrombosis and Hemostasis, from mechanisms totherapies
Kursnummer : 2484Antal högskolepoäng : 1.5Datum : 20151102 20151106Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Medicine, SolnaSärskild behörighet : Kursens lärandemål : The concept from bench to bed side and back will be reinforced at all levels.Therefore, at the end of the course the students should be able to: 1. Describe the molecular and cellularmechanisms of haemostasis and thrombosis, as well as the dynamic processes of primary haemostasis,secondary haemostasis, and thrombosis. 2. Explain the mechanisms underlying bleeding and thromboticdisorders. 3. Have a good understanding of current anticoagulant and antiplatelet therapies, and obtain aclear view of the challenges of future anticoagulant and antiplatelet drug developments. 4. Apply currentknowledge of thrombosis and haemostasis into future research design and to formulate new treatmentstrategies. 5. Sharpen the sense of critical appreciation of research literature, and strengthen their ability todevelop new research concepts through critical reading. Kursens innehåll : The course aims to bring in indepth knowledge of thrombosis and hemostasis, and toemphasize a translational view, from bench to bed side and back, of the hemostatic system to the students.The course is designed for the students who work in both basic and clinical aspects of hemostasis,thrombosis and cardiovascular research. The following aspects of hemostasis and thrombosis will bediscussed: biochemistry of the blood clotting system; cellcell and cellprotein interactions in thecardiovascular system in relation to thrombosis and bleeding disorders; crosstalks of the clotting systemwith inflammation, host defense and complement systems; diagnosis of bleeding and thrombotic disorders;therapeutic strategies to fight thrombosis and bleeding with the emphasis placed on new pharmacologicalconcepts.Arbetsformer : Lectures Seminars Group work Presentation of papers related to the key lectures Examination : Presentation of a paper related to key lectures Short written homework. Multiplechoicetest. Obligatoriska moment : To participate in the lectures, group work and presentation of the group work iscompulsory. The students who have missed the group work sessions can book extra session time within 4weeks to compensate the absence. Absence in lectures should be compensated for in accordance with thecourse director.Antal studenter : 12 25Urval av studenter : In case the course receives more applications than the maximal course slots.Selection of the participants is thus needed and made according to: 1) the relevance of the course syllabusfor the applicant's doctoral project (according to written motivation), 2) KI doctoral students prior todoctoral students from partner universities; 3) date for registration as a doctoral student (priority given toearlier registration date)Övrig information : Course will be held during week 45 (Monday Friday; 9:0016:30). Lecture hallbooked: CMM lecture hall, L8:00 at Karolinska University HospitalSolna. Lectures will be given by 14lecturers who are all wellestablished experts on their lecture subjects. The course has been given at KIover 20 years with about 10 course occasions. The course is well received by the course participants overthe years. The course in HT 2014 was highly remarked in the course evaluation (linked).
Kursansvarig : Nailin LiInstitutionen för medicin, Solna08[email protected]
Clinical Pharmacology UnitKarolinska University HospitalSolna17176Stockholm
Kontaktpersoner : Angela SilveiraInstitutionen för medicin, Solna08[email protected]
Title : Obesity basic science, clinical and epidemiologicalaspects
Kursnummer : 2498Antal högskolepoäng : 1.5Datum : 20151116 20151120Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Public Health SciencesSärskild behörighet : Kursens lärandemål : At the end of the course the students should be able to: 1, Discuss differenthypothesis and theories concerning the pathogenesis of obesity 2, Discuss occurence of obesity and comorbid diseases in society 3, Discuss current treatment methods of obesity and effects of these treatmentson comorbid diseases 4, Discuss methods to prevent obesity and methods used to evaluate effects oftreatment and prevention 5, To relate clinical and public health aspects of obesity to research aspects ofobesity Kursens innehåll : The course is to give an overview of obesity in society, pathogenesis and currenttreatment methods. These clinical examples will be used to demonstrate how one can design variousresearch projects related to obesity and comorbid disease preclinical, clinical, epidemiologcal andpreventive projects.Arbetsformer : The course will be based on lectures, work in small seminar groups and demonstration ofsurgery of obesity.Examination : Written examinationObligatoriska moment : Presence at lectures, group work and demonstration is mandatory. Absence mustbe compensated by a written task.Antal studenter : 10 20Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : The course will take place at Danderyd University Hospital.
Kursansvarig : Erik NäslundInstitutionen för kliniska vetenskaper, Danderyds [email protected]
Kontaktpersoner :
Title : Cancer cell energy metabolism
Kursnummer : 2515Antal högskolepoäng : 1.5Datum : 20151102 20151106Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of OncologyPathologySärskild behörighet : Kursens lärandemål : After the course, the student should be able to: describe and explain the role ofaltered cellular metabolism in cancer development and cancer progression; reflect upon the interactionbetween oncogenic signaling and tumor metabolism; discuss how tumor metabolism may be exploited inanticancer therapies and diagnosis/prognosis. Kursens innehåll : The course provides an introduction to cancer cell metabolism. Focus is on the roles ofoncogenic signaling and tumor microenvironment as drivers of tumor development and progression.Therapeutic and diagnostic perspectives exploiting the altered cancer metabolism are discussed.Arbetsformer : The course consists mainly of lectures, but also a minisymposium with invited internationalspeakers and group discussions/seminars.Examination : Examination is divided into two parts: Firstly, during active participation in the Meet thescientists seminar and in connection with the beehive group preparing that. Secondly, the students will begiven an individual written assignment to be delivered within two weeks after the end of the course. Thisassignment is a short project proposal within one topic chosen from a list of 10. The proposal will contain anoverview of the field which motivates a specific research question identified by the student and a brief workplan that explains how the question/hypothesis can be solved/investigated. Obligatoriska moment : Attendance at lectures is strongly advised. Participation in the beehive and Meetthe scientist session is mandatory. To compensate for absence due to e.g. illness the student may berequired to write a report and/or discuss the missed subject with the course leaders.Antal studenter : 10 20Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information :
Kursansvarig : Angelo De MilitoInstitutionen för onkologipatologi0851771766Angelo.De[email protected]
Forskningsringen 50
17462Sundbyberg
Kontaktpersoner : Mimmi ShoshanInstitutionen för onkologipatologi08517 754 [email protected]
Title : Basics of Qualitative research
Kursnummer : 2518Antal högskolepoäng : 1.5Datum : 20150914 20150918Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Clinical Science and Education, SödersjukhusetSärskild behörighet : Kursens lärandemål : At the end of the course the participants will be able: 1. To describe differenttheoretical starting points for qualitative inquiry 2. To apply knowledge of qualitative research methods fordiscussing rationales for the design of the qualitative inquiry 3. To critically compare of qualitative andquantitative research (basic assumptions of the qualitative research paradigm as it compares to thequantitative paradigm) 4. To describe the common essential elements of qualitative research including Howto select the appropriate: qualitative research methods based on phenomenon of interest setting for datacollection,study participants, data generation strategies (including individual interviews, focus groupdiscussion, written narratives, participants observation and field notes)and data analysis method 5. Tocritically comments on/evaluate the weaknesses and strengths of the studies(published papers) usingqualitative research in terms of research question, aim and method 6. To design a qualitative researchproposal in the field of health Kursens innehåll : The course will provide some of the most important information which students need tounderstand and implement successful qualitative research methods (including the common essentialelements of qualitative research). In addition the course will provide step by step guidance to examine andapply current qualitative methodologies as a way to generate, manage, analysis qualitative data andmoreover ,ethical considerations. The course will starts with the definition of qualitative research, basicassumptions and characteristics of qualitative research in comparison to quantitative research. Followingthat will be the notion of some common essential elements in qualitative methods such as: selecting themethods based on phenomenon of interest, using the literature review, choosing the setting for datacollection, selecting participants, generating data and content analysis .After that , practical principle to doqualitative inquiry will be addressed. Finally ethical considerations in qualitative research will be explained.Arbetsformer : The learning activities on the course are a mix of lectures, discussions, individual andgroup; interview, seminar, field observation and individual presentations.Examination : The course assessment will include formative and summative assessments. The formativeassessment (50%) will be made through Peer learning Activity, critic a qualitative paper, individual andgroup presentation, while summative assessment (50%) will be through a written examination andindividual qualitative proposal. In this way, the students are examined with both groupwise and individualpresentations.Obligatoriska moment : Active participation in the class discussions, individual and group assignment(individual and group interview and field observation), written assignment (an abstract of a qualitativeproposal) and student presentations is mandatory. Compensation according to the instructions of the coursedirector, which means absence in less than 2 lectures is acceptable and should be compensated by anindividual project related to that particular session.Antal studenter : 10 30Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information :
Kursansvarig : Hamid KhankehInstitutionen för klinisk forskning och utbildning, Södersjukhuset
Sjukhusbacken 10118 83
Stockholm
Kontaktpersoner : Jeanette Brynholt OhrmanInstitutionen för klinisk forskning och utbildning, Södersjukhuset086162935
Title : Cellular Reprogramming from basal mechanisms tomedical applications
Kursnummer : 2525Antal högskolepoäng : 1.5Datum : 20150914 20150918Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Cell and Molecular BiologySärskild behörighet : Kursens lärandemål : Upon completion of the course, the doctoral student will be familiar withmechanisms of nuclear reprogramming and how reprogramming techniques can be utilized in variousresearch areas. Emphasis will be put on providing the student with knowledge to critically read and evaluateresearch work in the reprogramming field, as well as on how appropriate reprogramming methods andprocedures can be applied in various research projects.Kursens innehåll : The course is composed of lectures that address different aspects of cellularreprogramming, i.e. how cellular identity can be changed, covering both basic scientific mechanisms as wellas experimental procedures of cellular reprogramming. The primary focus will be on the reprogramming offully differentiated cells to induced pluripotent stem (iPS) cells, but direct reprogramming from onedifferentiated state to another will be discussed as well. Controlled differentiation of pluripotent cells tospecific fates and the use of cellular reprogramming in disease modeling will be discussed.Arbetsformer : The learning activities are a mixture of lectures, discussions, group seminars and individualpresentations.Examination : The students are examined with individual presentations.Obligatoriska moment : Participation in the group discussions and student presentations is mandatory.Compensation is according to the instructions of the course director.Antal studenter : 10 15Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : The course is organized by the Research School of the Linné Center DBRM(Developmental Biology for Regegerative Medicine). More course information can be found at the ResearchSchool web pages at www.dbrm.se. The course is full time, given in English, and the course venue is theseminar room A216 at CMB, Berzeliusv 35.
Kursansvarig : Matti NikkolaInstitutionen för cell och molekylärbiologi
Kontaktpersoner :
Title : Neuropschopharmacology
Kursnummer : 2526Antal högskolepoäng : 2.0Datum : 20151123 20151201Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Clinical NeuroscienceSärskild behörighet : Kursens lärandemål : By the end of this course the PhD students should: 1) have achieved anunderstanding of the etiology of psychiatric disorders and are able to account for different hypotheses inthis field and how the major psychiatric diseases are treated. 2) possess skills in handling methods andanimal models for studying the effects of drugs on different symptoms of psychiatric diseases. 3) be able toevaluate data and preclinical research within the research fields of psychiatric diseases. Kursens innehåll : This course will focus on pharmacological strategies in the treatment of psychiatricdisorders, e.g. schizophrenia, major depression etc. The course will also discuss methods and models whichare used in preclinical research concerning the mechanisms of action of different drugs in the treatment ofthese disorders. Arbetsformer : The pedagogic framing of the course include lectures given by invited clinicians andresearchers within the field of psychiatric disorders. We will also have demonstrations of keymodels/methods which are used in specific research projects.Examination : Written exam Obligatoriska moment : The demonstrations are mandatory. The student has to compensate absensefrom this part with a written description of the model/method.Antal studenter : 15 35Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information :
Kursansvarig : Kent JardemarkInstitutionen för Fysiologi och Farmakologi08[email protected]
Kontaktpersoner : Vasco SousaInstitutionen för klinisk neurovetenskap
Title : The major global infectious diseases: tuberculosis andHIV
Kursnummer : 2536Antal högskolepoäng : 1.5Datum : 20151123 20151127Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Medicine, SolnaSärskild behörighet : Kursens lärandemål : At the end of the course the students should be able to: describe the diseasemechanisms of TB and HIV infection and discuss important differences and similarities between theseinfections and their impact on global health. explain the challenges regarding clinical symptoms,diagnosis, treatment and drugresistance, vaccine strategies and TB/HIV coinfection. analyse how clinicalmanagement of TB and HIV can be integrated and linked to molecular knowledge as well as public healthissues. discuss and critically evaluate current issues in TB and HIV research including prevention andcontrol in low, middle and high income countries. Kursens innehåll : An overview of tuberculosis (TB) and HIV/AIDS infection and disease including relevantvirology and bacteriology, TB/HIV coinfection, clinical management, international public health aspects,immunology and pathogenesis, diagnostic methods and principles of vaccines, therapy and drug resistanceas well as novel research strategies.Arbetsformer : The course will consist of a mixture of lectures by invited speakers, seminars and practicalsessions i.e. study questions and group assignments. The students will have access to computer rooms.Examination : Study questions and group assignment will be presented (both orally and in written) anddiscussed by the students and facilitators on a daily basis. Thus, the individual learning outcome will beassessed on a daily basis. Furthermore, on the last day of the course, concept maps will be used tosummarize individual learning outcome.Obligatoriska moment : It is compulsory to attend all the lectures and sessions, including the groupassignment. Absence has to be compensated by an individual written assignment provided by the courseleader.Antal studenter : 15 30Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : The course will take place at Karolinska Universityhospital Solna, at the Center forMolecular Medicine (CMM), MondayFriday 08.3016.30. We plan to invite several speakers from TB/HIVhigh endemic countries to talk about reallife experiences
Kursansvarig : Annelie TjernlundInstitutionen för medicin, Solna
Jordgränd 44
192 74Sollentuna
Kontaktpersoner : Anne RasikariInstitutionen för medicin, Solna08517 718 [email protected]
B3:03
Title : Writing Science and Information Literacy
Kursnummer : 2561Antal högskolepoäng : 3.0Datum : 20150824 20151016Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Karolinska Institutet University LibrarySärskild behörighet : Kursens lärandemål : Demonstrate understanding of how to write an original scientific article and submitit for publication Demonstrate ability to write other types of texts required for a scientific career Demonstrate ability to give, take, and make use of constructive criticism Demonstrate the ability to searchand manage the medical sciences literature in a structured way Demonstrate the ability to use resourceswhich facilitate choosing a journal to publish your research Describe aspects of postpublication evaluationand processing of the medical sciences literatureKursens innehåll : Basic of scientific writing Writing an original scientific paper Supporting the text Writingin other contexts The publication process Searching the literature Managing the literature Choosing ajournal Evaluating published science KIpostpublication processing Arbetsformer : This webbased course will be held using the learning management system PingPong.Content will be learnt with various learning objects and learning practised by exercises. Formative feedbackwill be given by teachers/peer/selfassessment. Writing and IT skills will be developed.Examination : The intended learning outcomes are assessed in the summative examination. Participantswill write and rewrite a grant application and popular science summary based on teacher and peerfeedback. Participants will also complete a number of assignments which demonstrate their ability to use anumber of relevant IT resources in a context of scientific communication.Obligatoriska moment : There will be a number of obligatory tests and assignments to be completed.Antal studenter : 18 22Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : This is an entirely webbased course with teacher support but no physical meetings.The course is read at 25% of fulltime.
Kursansvarig : David HerronKarolinska Institutet Universitetsbibliotek08524 841 [email protected]
Berzelius 7B
17177Stockholm
Kontaktpersoner :
Title : Introduction to R statistical analysis for biologists
Kursnummer : 2570Antal högskolepoäng : 1.5Datum : 20151109 20151113Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Cell and Molecular BiologySärskild behörighet : Kursens lärandemål : After the completion of the course, the participants will be able to make use of Rfor exploring and analyzing data sets. More specifically, the participants will be able to manage data sets,perform descriptive data analysis, generate plots for graphical display of data, and to perform tests such asRegression and ANOVA. A very specific goal is to provide the participants with a longterm tool and theguidelines for improving their knowledge on it. Kursens innehåll : Data sets and formats in R. Descriptive statistics. Graphical display of data. Classicaltests. Regression, ANOVA, KruskalWallis. Experimental design. Graphical display of analysis. Use ofdocumentation in R. Arbetsformer : The course consists of lectures, computer excercises and project work.Examination : The acquired knowledge and skills will be examined in two ways: by successfully completingcomputer exercises and by a individual project (analysis of a selected data set; which can be provided bythe student).Obligatoriska moment : Attendance is compulsory in lectures and computer excercises. Absence fromobligatory moments is compensated according to the instructions of the course director.Antal studenter : 10 15Urval av studenter : Selection is based on the relevance of the course content for the doctoral project, thepersonal motivation included in the course application and the date for registration as a doctoral student(priority given to earlier registration date).Övrig information : The course takes place at CMB at KI Solna campus, in the seminar room A216.Entrance Berzeliusv 35. The course director is Dr. David GomezCabrero at the Department of Medicine,Solna. Email [email protected].
Kursansvarig : Matti NikkolaInstitutionen för cell och molekylärbiologi
Kontaktpersoner :
Title : Noncoding RNA and cancer
Kursnummer : 2583Antal högskolepoäng : 1.5Datum : 20151130 20151204Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of OncologyPathologySärskild behörighet : Kursens lärandemål : At the end of the course, the students are expected to be able to: understand thediversity of noncoding RNAs and their importance in tumorigenesis and tumor progression. describevarious methodologies for noncoding RNA research, account for applications and apply relevant approachesin their own projects.Kursens innehåll : Noncoding RNAs are key regulators of gene expression with important impact in manybiological processes. Recent research has identified different classes of noncoding RNA and their roles incancer development and progression. Through short introductory lectures and indepth discussion of keypapers from the recent literature, this course will cover an uptodate introduction to the biogenesis ofdiverse noncoding RNAs (including small RNAs and long noncoding intergenic RNAs) and theirmechanisms of gene regulation, methodologies for noncoding RNA research, expression and function ofnoncoding RNAs in cancer development, and their potential clinical implications.Arbetsformer : The course consists of lectures and problembased discussions. In addition, the studentsare required to submit a research proposal on a topic related to noncoding RNA and cancer.Examination : The examination of the course includes problembased discussions, and reviewing andpresenting individual research proposal related to noncoding RNA. Obligatoriska moment : The students are expected to attend all lectures and problembased discussions,as well as to complete all assignments. In the case of absence, the student will be asked to compensate bycompleting another written assignment given by the course organizer. Antal studenter : 12 20Urval av studenter : Selection will be based on the relevance of the course to the student's researchproject and the personal motivation for participation in this course.Övrig information : This fulltime course will be held at Cancer Center Karolinska, Karolinska UniversityHospitalSolna.
Kursansvarig : Wengonn LuiInstitutionen för onkologipatologi0851773930Weng[email protected]
Kontaktpersoner :
Title : Neurogenetics
Kursnummer : 2600Antal högskolepoäng : 1.5Datum : 20150928 20151002Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Neurobiology, Care Sciences and SocietySärskild behörighet : Kursens lärandemål : I) The student will be able to understand and describe the major differences anduses of human genetic studies of neurogenetic diseases using i) Twinstudies, ii) population based studies,iii) casecontrol studies, iv) family studies. Students will have an in depth knowledge and understanding ofselected neurologic conditions such as Alzheimer disease, trinucleotide repeat disorders, their genetic basisand an insight into the molecular pathogenesis, if known. II) The students will also be able to describe howgenetic studies can be used to increase our understanding of the biological basis of neurological conditions.III) The students will be able to contribute substantially to critical evaluation and presentation of scientificarticles in the field of neurogenetics. IV) The students will have an understanding of the different genetictechniques and platforms available for studies in human (neurological) conditions.V) The students will havean insight in the application/use of genetic testing for neurological diseases.Kursens innehåll : I) The course will give examples of how different types of genetic studies can help usidentify genes involced in the pathogenesis of neurological disease: i) Twinstudies, ii) population basedstudies, iii) casecontrol studies, iv) family studies. II) The course will give examples of different genedefects in neurological diseases such as trinucleotide repeats, point mutations, copy number variations,susceptibility genes, rearrangements, transciptional regulation and epigenetics. III) The course will providean in depth understanding of the genetics of selected neurological diseases and how these geneticdysfunctions help us understand the molecular mechanisms of disease.Arbetsformer : Daily classroom lectures. The last session on Monday through Thursday will be in aworkshop/seminar format where the students prepare a group presentation of a selected topic/geneticneurological disease. The presentation will be on the last day of the course and consitutes the examination.Examination : The examination will be on the last day of the course and it will consist of i) participating ina group presentation of a selected topic/genetic neurological disease ii) participate as an active audiencewhen other groups have their presentations. Every student will be assessed individually in accordance withthe intended learning outcomes of the course.Obligatoriska moment : All lectures/seminars are compulsory and in case of absence, the session can becompensated by a short written report using the literature after agreement with the course director.Antal studenter : 7 20Urval av studenter : Selection will be based on 1) the applicant's written motivation 2) the date ofadmission to doctoral education. Övrig information : The course is part if the Frontiers Courses in Neuroscience and the course participantswill be a mix of master students and PhDstudents. This is a fulltime course (9:0017:00) and will be heldat the Karolinska Institutet. Details about specific lecturehalls and seminar rooms will be provided inAugust 2015.
Kursansvarig : Caroline GraffInstitutionen för neurobiologi, vårdvetenskap och samhä[email protected]
KIADRC, Novum plan 5
141 86Stockholm
Kontaktpersoner : Annica RönnbäckInstitutionen för neurobiologi, vårdvetenskap och samhälle
Title : Brain development and Neurodevelopmental disorders
Kursnummer : 2605Antal högskolepoäng : 1.5Datum : 20150921 20150925Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of NeuroscienceSärskild behörighet : Background in medicine, biomedicine, neuroscience or psychology.Kursens lärandemål : The aim of this translational neuroscience course is to provide an overview on theemerging field of developmental cognitive neuroscience. In particular, we will focus on cortical braindevelopment, development of cognitive functions in typically developing children and children withneurodevelopmental disorders e.g., AttentionDeficit /Hyperactivity Disorder (ADHD) and Autism SpectrumDisorders (ASD), and the role of both genetic and environmental factors in the etiology of these disorders.During the course, students will learn to critically evaluate and explain in presentations the content oforiginal articles. After the course students should be able to: 1) Describe fundamentalneurodevelopmental processes (e.g. neurogenesis, neuronal migration, synaptogenesis). 2) Describegenetic and molecular mechanisms controlling cortical development. 3) Describe cognitive deficits amongneurodevelopmental disorders (e.g., ADHD and ASD). 4) Postulate potential genetic /molecularmechanisms underlying cognitive deficits in children with neurodevelopmental disorders Kursens innehåll : Course Curriculum Part I: Fundamentals of Developmental Neurobiology 1. Earlybrain development, construction of neural circuits, and modification of neural circuits as a result ofexperience 2. Genetic control of cortical development 3. Effects of sex hormones on brain development Part II: Functional Brain development in humans 1. AgeRelated Changes in executive function (e.g.,working memory) 2. Working memory, and training induced plasticity 3. The molecular genetics ofexecutive function Part III: Neurodevelopmental Aspects of Clinical Disorders 1. The neurobiology andgenetics of ADHD 2. Advances in the Cognitive Neuroscience of ASD 3. Childhood psychiatric disorders asanomalies in neurodevelopmental trajectories Arbetsformer : A variety of teaching and learning strategies are presented during the course to facilitatestudents learning. These strategies include short lectures, small group discussions, computerbasedlearning, and problem based learning.Examination : The examination will consist of an oral group presentation focusing on cognitive deficitsfound in children with neurodevelopmental disorders (e.g. ADHD and ASD) and the potential genetic /molecular mechanisms underlying these deficits. At the beginning of the course, students will be assignedinto different working group themes e.g., ADHD and ASD. These groups will work together throughout thecourse and prepare for the final oral presentation. During the course there will also be formativeassessments to give students immediate feedback about their learning process during the differentmilestones of the course and clarify any questions relating to the final assessment. Course grades Pass:Students demonstrate an understanding of brain development and cognitive deficits found in neurodevelopmental disorders, and can postulate/hypothesize potential genetic / molecular mechanismsunderlying these deficits based upon findings from both basic and clinical literature.Obligatoriska moment : All lectures and seminars are mandatory. In order to make up for absence of aparticular lecture, the students will be required to read specific chapters from the recommended literatureand write a short report.Antal studenter : 15 30Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : We are very honored to have Professor Pasko Rakic from Yale University School ofMedicine as our keynote speaker and other top international speakers, including Professor Derrick MacFabefrom the University of Western Ontario. The course will take place at KI Solna campus (Monday throughFriday between 09:0016:30). Note: The title of the course will change to "NeurodevelopmentalDisorders: From basic research to the clinic".
Kursansvarig : Rochellys HeijtzInstitutionen för neurovetenskap08[email protected]
Retzius Väg 8
17177
Stockholm
Kontaktpersoner :
Title : Mechanisms of Gene Regulation in Metabolism
Kursnummer : 2608Antal högskolepoäng : 1.5Datum : 20151105 20151111Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Physiology and PharmacologySärskild behörighet : Kursens lärandemål : At the end of the course students will understand and be able to discuss thedifferent mechanisms that regulate gene expression. They will be able to describe how these processes canaffect metabolic disease and disease progression. The students will be able to choose the most appropriatemethodologies to study diverse aspects of gene regulation in metabolism.Kursens innehåll : This course aims at giving students an overview of the current understanding of howmetabolism and metabolic dysfunction are controlled at the level of gene regulation. During one week,students will focus on the genetic and epigenetic mechanisms that affect transcriptional output in diverseorgans and tissues in health and disease situations. This will include: basic mechanisms of genetranscription, transcription factors and coregulators, mRNA splicing and genetic variability, the chromatinlandscape and associated DNA and histone modifications, noncoding RNAs and regulation of geneexpression. Attention will be given to single gene analysis as well as global regulation of gene expression.In each module the student will be introduced to the basic concepts in the field and analyze situations inwhich dysregulation of the processes under examination leads to metabolic disease. Each module willinclude a chapter dedicated to the presentation and discussion of current experimental approaches relevantto research in that particular field of science.Arbetsformer : This course will consist mainly of lectures and group discussions covering both theoreticaland practical questions related to the different areas of gene regulation and metabolism. Some sessions willbe dedicated to problem solving and presentation of stateoftheart methodologies relevant to research ineach field.Examination : Examination will consist of an oral presentation in which students discuss an example ofmetabolic disorder caused by dysregulation of gene expression and propose a research plan to further studythat problem. The research plan should include appropriate methodology learned during the course.Obligatoriska moment : Presence at lectures, group work, and final presentation and discussion ismandatory. To compensate for absence a written essay on the missed topic must be performed.Antal studenter : 10 30Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : The course duration is 5 weekdays and it's divided in two blocks. The first block (Nov5 6) addresses more general knowledge in mechanisms of gene regulation with focus on metabolism, andthe second (Nov 9 11), the more specialised course content. We always have an invited lecturer who willbe announced closer to the date since we are still awaiting confirmation.
Kursansvarig : Jorge RuasInstitutionen för Fysiologi och Farmakologi(08)[email protected]
von Eulers väg 8
17177Stockholm
Kontaktpersoner :
Title : Basic Course in Medical Statistics a distance course
Kursnummer : 2609Antal högskolepoäng : 3.0Datum : 20150921 20151002Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Learning, Informatics, Management and EthicsSärskild behörighet : Kursens lärandemål : The course participants shall after the course be able to perform basic summaries,analyses and presentation of data, as well as have enhanced their ability to recognise, understand andcritically view the statistics being presented in medical articles.Kursens innehåll : The course is an introduction to basic statistical principles and how statistics play a partin medical research. Concepts being treated are hypothesis, type I error, type II error, estimates,measurement of dispersion, regression analysis, inference making and how to present the results.Arbetsformer : The course will be a distance course by using the platform edX. The course containsvideolectures, exercises with suggested solutions and 2 statistical software demonstration videos Statistica and SPSS. The first and last day of the course will be facetoface with an introduction the firstday and seminars and group discussions the last day. In addition to the different videomoments the timewill be spent working on computer based exercises and reading the course literature. Examination : Course requirements: Correct answers on the computer based exercises. The doctoralstudent will during the seminars have to demonstrate their ability to recognise, understand and criticize thestatistics presented in the medical articles by active participation in the discussions. Obligatoriska moment : Attendance is mandatory for the seminars on the last day of the course. If thestudent is absent, he or she can compensate the absence by handing in written answers to questionsconcerning the compulsory moments.Antal studenter : 40 50Urval av studenter : Date for registration as a doctoral student (priority given to earlier registration date).Please make sure that you have entered the correct registration date for doctoral education in yourpersonal profile.Övrig information :
Kursansvarig : Mesfin TessmaInstitutionen för lärande, informatik, management och etik
Kontaktpersoner : Margareta KrookBrandtInstitutionen för lärande, informatik, management och etik52487118Margareta.Krook[email protected]
Title : Frontiers in Cogntive Neuroscience
Kursnummer : 2616Antal högskolepoäng : 1.5Datum : 20150914 20150918Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of NeuroscienceSärskild behörighet : 180 hp in medicine, biomedicine, biology, psychology, or cognitive science, ormaster degree in medical imaging engineeringKursens lärandemål : After the course the student must be able to: (1) account for current concepts andkey principles of cognitive neuroscience; (2) show an understanding of the interdisiplinary nature ofcognitive neuroscience with its roots in both psychology and neuroscience; (3) discuss and criticallyevaluate scientific articles in the field; (4) To show basic knowledge about the strengths and weakness ofthe different stateoftheart methods used in cognitive neuroscience.Kursens innehåll : (1) Series of lectures informing about the state of art knowledge about: (i) Perceptionand sensory mechanisms; (ii) action planning and execution (iii); (iv) sex differences in the brain; (v)higher cognitive functions including working memory and creativity; (vi) memory; and (vii) cognitive effectsof aging (2) Seminars where the students will critically discuss key published papers, and grouppresentations where they will present their analyses and conclusions for the whole group. Arbetsformer : Lectures, seminars, and group presentations.Examination : The oral presentation and group discussions during the last day¿s seminar count asexamination. We will assess individual students¿ ability to discuss and reason about current issues andproblems in cognitive neuroscience. Obligatoriska moment : The group seminar is obligatory. In addition to that, the students are assumed totake part in the lectures. The student will be able to compensate missing attendance by submitting writtenreports on the missed material later.Antal studenter : 12 30Urval av studenter : Selection will be based on 1) having signed up for the doctoral programme inNeuroscience or similar field, 2) the relevance of the course syllabus for the applicant's doctoral project(according to written motivation), 3) date for registration as a doctoral student (priority given to earlierregistration date)<br> For more information about the doctoral programmes at KI, see:https://internwebben.ki.se/en/doctoralprogrammes0Övrig information : Full day course, Monday to Friday.
Kursansvarig : Henrik EhrssonInstitutionen för [email protected]
Retzius väg 8
17177 Stockholm
Kontaktpersoner :
Title : Write your research results and get them published
Kursnummer : 2618Antal högskolepoäng : 3.0Datum : 20151012 20151023Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Women's and children's healthSärskild behörighet : None.Kursens lärandemål : AFTER ATTENDING THE COURSE, THE PhD STUDENT SHOULD BE ABLE TO: Explain the characteristics and disposition of different written presentation media and decide which forum isthe most suitable for a specific text Understand, and apply, the terminology associated with scientificwriting Write an abstract Use the correct structure and language to compose a scientific paper andfollow the editorial requirements Revise a manuscript according to a checklist with the most commonlanuage and structure mistakes in scientific writing Use the focus points in a scientific paper (where thereaders focus their reading) Identify the main scope and focus of the research and summarizeinformation aligned to the target group Apply the structure of popular science writing and use popularscience as a tool for presentations Give a poster presentation Design a scientific poster and reflectupon structure, language and style Understand the ethics in publication Use the software EndNote forreference management Search for references in databases (e.g. PubMed) and decide what sources arereliable Respond to the reviewer´s comments Write a cover letter Reflect on his/her owndevelopment as a writer of different texts during the course Kursens innehåll : THE MAIN SCOPE OF THE COURSE is how to write about research in different contextsand forums. THE CONTENT OF THE COURSE: Terminology associated to scientific writing Designingand writing a poster an abstract a draft for a research paper a project plan a reply to the reviewer´scomments a cover letter a popular science paper The writing process: structure, language, style Editorial requirements of different journals Summarising and presenting information aiming at the targetaudience Identifying the main scope of a research project References and reference management(EndNote software) Data base search Basic rhetoric for poster presentations References Ethics inpublication Arbetsformer : Lectures, seminares, writing exercises, group assignments and practical exercises. As partof the learning process, the Ph.D students will be members of inclass review groups, giving feedback totheir colleagues.Examination : 1) Written assignments reflecting the learning goals of the course: draft for scientific andpopular science paper, poster, electronic poster, and abstract. 2) Evaluation sessions, where the PhDstudents give each other feed back on the written assignments as a part of the learning process 3) Posterpresentation, where the PhD students present their posters to another course participant (there are nopresentations in front of a larger group)Obligatoriska moment : Lectures, workshops, evaluation sessions, and group assignments as well as allwritten assignments. Absence can be compensated: a) during next years course b) individual assigments Antal studenter : 18 20Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to LATER registration date)Övrig information : Welcome to apply for the Ph. D. writing course 2618 on Scientific and popular sciencewriting! <p> During the course, you will have the opportunity to write a draft for a scientific manuscript, anabstract, a popular science article, a press release, and to design a poster. The popular science writing isused as a tool for finding the core of your research project, poster design and presentations. <p> Thecourse also covers: presentation techniques for presenting your poster at a conference, how to answer thereviewer's questions, letter to the editor, review article, cover letter, and ethics in publication. New Ph.D.students are given priority to the course, as we believe that writing is an essential skill that should beacquired as soon as possible during your time as a doctoral student. However, students who have alreadypublished articles will benefit as much from the course as newly registered students, as you write aboutyour own research projects, starting on your own level, and in your own pace. The course curriculum takesinto consideration that all students have different background knowledge and are on different stages oftheir doctoral education. In order to participate in the course, you need either some preliminary data fromyour own research project or other data provided by your supervisor to work with. Our intention is that youshould be able to use everything you write and design during the course: this will keep motivation high andmake sure that you are spending your time in the best possible way. <p> Please address all questions toAnna Hildenbrand Wachtmeister: [email protected] Cellphone: 0707890607 <p> We are lookingforward to meeting you in the course!
Kursansvarig :
Anna Hildenbrand WachtmeisterInstitutionen för kvinnors och barns hä[email protected]
Kontaktpersoner : Anna Hildenbrand WachtmeisterInstitutionen för kvinnors och barns hä[email protected]
Lalit KumarInstitutionen för kvinnors och barns hälsa
Title : Write your research results and get them published
Kursnummer : 2618Antal högskolepoäng : 3.0Datum : 20150928 20151009Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Women's and children's healthSärskild behörighet : None.Kursens lärandemål : AFTER ATTENDING THE COURSE, THE PhD STUDENT SHOULD BE ABLE TO: Explain the characteristics and disposition of different written presentation media and decide which forum isthe most suitable for a specific text Understand, and apply, the terminology associated with scientificwriting Write an abstract Use the correct structure and language to compose a scientific paper andfollow the editorial requirements Revise a manuscript according to a checklist with the most commonlanuage and structure mistakes in scientific writing Use the focus points in a scientific paper (where thereaders focus their reading) Identify the main scope and focus of the research and summarizeinformation aligned to the target group Apply the structure of popular science writing and use popularscience as a tool for presentations Give a poster presentation Design a scientific poster and reflectupon structure, language and style Understand the ethics in publication Use the software EndNote forreference management Search for references in databases (e.g. PubMed) and decide what sources arereliable Respond to the reviewer´s comments Write a cover letter Reflect on his/her owndevelopment as a writer of different texts during the course Kursens innehåll : THE MAIN SCOPE OF THE COURSE is how to write about research in different contextsand forums. THE CONTENT OF THE COURSE: Terminology associated to scientific writing Designingand writing a poster an abstract a draft for a research paper a project plan a reply to the reviewer´scomments a cover letter a popular science paper The writing process: structure, language, style Editorial requirements of different journals Summarising and presenting information aiming at the targetaudience Identifying the main scope of a research project References and reference management(EndNote software) Data base search Basic rhetoric for poster presentations References Ethics inpublication Arbetsformer : Lectures, seminares, writing exercises, group assignments and practical exercises. As partof the learning process, the Ph.D students will be members of inclass review groups, giving feedback totheir colleagues.Examination : 1) Written assignments reflecting the learning goals of the course: draft for scientific andpopular science paper, poster, electronic poster, and abstract. 2) Evaluation sessions, where the PhDstudents give each other feed back on the written assignments as a part of the learning process 3) Posterpresentation, where the PhD students present their posters to another course participant (there are nopresentations in front of a larger group)Obligatoriska moment : Lectures, workshops, evaluation sessions, and group assignments as well as allwritten assignments. Absence can be compensated: a) during next years course b) individual assigments Antal studenter : 18 20Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to LATER registration date)Övrig information : Welcome to apply for the Ph. D. writing course 2618 on Scientific and popular sciencewriting! <p> During the course, you will have the opportunity to write a draft for a scientific manuscript, anabstract, a popular science article, a press release, and to design a poster. The popular science writing isused as a tool for finding the core of your research project, poster design and presentations. <p> Thecourse also covers: presentation techniques for presenting your poster at a conference, how to answer thereviewer's questions, letter to the editor, review article, cover letter, and ethics in publication. New Ph.D.students are given priority to the course, as we believe that writing is an essential skill that should beacquired as soon as possible during your time as a doctoral student. However, students who have alreadypublished articles will benefit as much from the course as newly registered students, as you write aboutyour own research projects, starting on your own level, and in your own pace. The course curriculum takesinto consideration that all students have different background knowledge and are on different stages oftheir doctoral education. In order to participate in the course, you need either some preliminary data fromyour own research project or other data provided by your supervisor to work with. Our intention is that youshould be able to use everything you write and design during the course: this will keep motivation high andmake sure that you are spending your time in the best possible way. <p> Please address all questions toAnna Hildenbrand Wachtmeister: [email protected] Cellphone: 0707890607 <p> We are lookingforward to meeting you in the course!
Kursansvarig :
Anna Hildenbrand WachtmeisterInstitutionen för kvinnors och barns hä[email protected]
Kontaktpersoner : Anna Hildenbrand WachtmeisterInstitutionen för kvinnors och barns hä[email protected]
Lalit KumarInstitutionen för kvinnors och barns hälsa
Title : Write your research results and get them published
Kursnummer : 2618Antal högskolepoäng : 3.0Datum : 20151116 20151127Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Women's and children's healthSärskild behörighet : None.Kursens lärandemål : AFTER ATTENDING THE COURSE, THE PhD STUDENT SHOULD BE ABLE TO: Explain the characteristics and disposition of different written presentation media and decide which forum isthe most suitable for a specific text Understand, and apply, the terminology associated with scientificwriting Write an abstract Use the correct structure and language to compose a scientific paper andfollow the editorial requirements Revise a manuscript according to a checklist with the most commonlanuage and structure mistakes in scientific writing Use the focus points in a scientific paper (where thereaders focus their reading) Identify the main scope and focus of the research and summarizeinformation aligned to the target group Apply the structure of popular science writing and use popularscience as a tool for presentations Give a poster presentation Design a scientific poster and reflectupon structure, language and style Understand the ethics in publication Use the software EndNote forreference management Search for references in databases (e.g. PubMed) and decide what sources arereliable Respond to the reviewer´s comments Write a cover letter Reflect on his/her owndevelopment as a writer of different texts during the course Kursens innehåll : THE MAIN SCOPE OF THE COURSE is how to write about research in different contextsand forums. THE CONTENT OF THE COURSE: Terminology associated to scientific writing Designingand writing a poster an abstract a draft for a research paper a project plan a reply to the reviewer´scomments a cover letter a popular science paper The writing process: structure, language, style Editorial requirements of different journals Summarising and presenting information aiming at the targetaudience Identifying the main scope of a research project References and reference management(EndNote software) Data base search Basic rhetoric for poster presentations References Ethics inpublication Arbetsformer : Lectures, seminares, writing exercises, group assignments and practical exercises. As partof the learning process, the Ph.D students will be members of inclass review groups, giving feedback totheir colleagues.Examination : 1) Written assignments reflecting the learning goals of the course: draft for scientific andpopular science paper, poster, electronic poster, and abstract. 2) Evaluation sessions, where the PhDstudents give each other feed back on the written assignments as a part of the learning process 3) Posterpresentation, where the PhD students present their posters to another course participant (there are nopresentations in front of a larger group)Obligatoriska moment : Lectures, workshops, evaluation sessions, and group assignments as well as allwritten assignments. Absence can be compensated: a) during next years course b) individual assigments Antal studenter : 18 20Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to LATER registration date)Övrig information : Welcome to apply for the Ph. D. writing course 2618 on Scientific and popular sciencewriting! <p> During the course, you will have the opportunity to write a draft for a scientific manuscript, anabstract, a popular science article, a press release, and to design a poster. The popular science writing isused as a tool for finding the core of your research project, poster design and presentations. <p> Thecourse also covers: presentation techniques for presenting your poster at a conference, how to answer thereviewer's questions, letter to the editor, review article, cover letter, and ethics in publication. New Ph.D.students are given priority to the course, as we believe that writing is an essential skill that should beacquired as soon as possible during your time as a doctoral student. However, students who have alreadypublished articles will benefit as much from the course as newly registered students, as you write aboutyour own research projects, starting on your own level, and in your own pace. The course curriculum takesinto consideration that all students have different background knowledge and are on different stages oftheir doctoral education. In order to participate in the course, you need either some preliminary data fromyour own research project or other data provided by your supervisor to work with. Our intention is that youshould be able to use everything you write and design during the course: this will keep motivation high andmake sure that you are spending your time in the best possible way. <p> Please address all questions toAnna Hildenbrand Wachtmeister: [email protected] Cellphone: 0707890607 <p> We are lookingforward to meeting you in the course!
Kursansvarig :
Anna Hildenbrand WachtmeisterInstitutionen för kvinnors och barns hä[email protected]
Kontaktpersoner : Anna Hildenbrand WachtmeisterInstitutionen för kvinnors och barns hä[email protected]
Lalit KumarInstitutionen för kvinnors och barns hälsa
Title : Write your research results and get them published
Kursnummer : 2618Antal högskolepoäng : 3.0Datum : 20150907 20150918Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Women's and children's healthSärskild behörighet : None.Kursens lärandemål : AFTER ATTENDING THE COURSE, THE PhD STUDENT SHOULD BE ABLE TO: Explain the characteristics and disposition of different written presentation media and decide which forum isthe most suitable for a specific text Understand, and apply, the terminology associated with scientificwriting Write an abstract Use the correct structure and language to compose a scientific paper andfollow the editorial requirements Revise a manuscript according to a checklist with the most commonlanuage and structure mistakes in scientific writing Use the focus points in a scientific paper (where thereaders focus their reading) Identify the main scope and focus of the research and summarizeinformation aligned to the target group Apply the structure of popular science writing and use popularscience as a tool for presentations Give a poster presentation Design a scientific poster and reflectupon structure, language and style Understand the ethics in publication Use the software EndNote forreference management Search for references in databases (e.g. PubMed) and decide what sources arereliable Respond to the reviewer´s comments Write a cover letter Reflect on his/her owndevelopment as a writer of different texts during the course Kursens innehåll : THE MAIN SCOPE OF THE COURSE is how to write about research in different contextsand forums. THE CONTENT OF THE COURSE: Terminology associated to scientific writing Designingand writing a poster an abstract a draft for a research paper a project plan a reply to the reviewer´scomments a cover letter a popular science paper The writing process: structure, language, style Editorial requirements of different journals Summarising and presenting information aiming at the targetaudience Identifying the main scope of a research project References and reference management(EndNote software) Data base search Basic rhetoric for poster presentations References Ethics inpublication Arbetsformer : Lectures, seminares, writing exercises, group assignments and practical exercises. As partof the learning process, the Ph.D students will be members of inclass review groups, giving feedback totheir colleagues.Examination : 1) Written assignments reflecting the learning goals of the course: draft for scientific andpopular science paper, poster, electronic poster, and abstract. 2) Evaluation sessions, where the PhDstudents give each other feed back on the written assignments as a part of the learning process 3) Posterpresentation, where the PhD students present their posters to another course participant (there are nopresentations in front of a larger group)Obligatoriska moment : Lectures, workshops, evaluation sessions, and group assignments as well as allwritten assignments. Absence can be compensated: a) during next years course b) individual assigments Antal studenter : 18 20Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to LATER registration date)Övrig information : Welcome to apply for the Ph. D. writing course 2618 on Scientific and popular sciencewriting! <p> During the course, you will have the opportunity to write a draft for a scientific manuscript, anabstract, a popular science article, a press release, and to design a poster. The popular science writing isused as a tool for finding the core of your research project, poster design and presentations. <p> Thecourse also covers: presentation techniques for presenting your poster at a conference, how to answer thereviewer's questions, letter to the editor, review article, cover letter, and ethics in publication. New Ph.D.students are given priority to the course, as we believe that writing is an essential skill that should beacquired as soon as possible during your time as a doctoral student. However, students who have alreadypublished articles will benefit as much from the course as newly registered students, as you write aboutyour own research projects, starting on your own level, and in your own pace. The course curriculum takesinto consideration that all students have different background knowledge and are on different stages oftheir doctoral education. In order to participate in the course, you need either some preliminary data fromyour own research project or other data provided by your supervisor to work with. Our intention is that youshould be able to use everything you write and design during the course: this will keep motivation high andmake sure that you are spending your time in the best possible way. <p> Please address all questions toAnna Hildenbrand Wachtmeister: [email protected] Cellphone: 0707890607 <p> We are lookingforward to meeting you in the course!
Kursansvarig :
Anna Hildenbrand WachtmeisterInstitutionen för kvinnors och barns hä[email protected]
Kontaktpersoner : Anna Hildenbrand WachtmeisterInstitutionen för kvinnors och barns hä[email protected]
Lalit KumarInstitutionen för kvinnors och barns hälsa
Title : Write your research results and get them published
Kursnummer : 2618Antal högskolepoäng : 3.0Datum : 20151130 20151211Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Women's and children's healthSärskild behörighet : None.Kursens lärandemål : AFTER ATTENDING THE COURSE, THE PhD STUDENT SHOULD BE ABLE TO: Explain the characteristics and disposition of different written presentation media and decide which forum isthe most suitable for a specific text Understand, and apply, the terminology associated with scientificwriting Write an abstract Use the correct structure and language to compose a scientific paper andfollow the editorial requirements Revise a manuscript according to a checklist with the most commonlanuage and structure mistakes in scientific writing Use the focus points in a scientific paper (where thereaders focus their reading) Identify the main scope and focus of the research and summarizeinformation aligned to the target group Apply the structure of popular science writing and use popularscience as a tool for presentations Give a poster presentation Design a scientific poster and reflectupon structure, language and style Understand the ethics in publication Use the software EndNote forreference management Search for references in databases (e.g. PubMed) and decide what sources arereliable Respond to the reviewer´s comments Write a cover letter Reflect on his/her owndevelopment as a writer of different texts during the course Kursens innehåll : THE MAIN SCOPE OF THE COURSE is how to write about research in different contextsand forums. THE CONTENT OF THE COURSE: Terminology associated to scientific writing Designingand writing a poster an abstract a draft for a research paper a project plan a reply to the reviewer´scomments a cover letter a popular science paper The writing process: structure, language, style Editorial requirements of different journals Summarising and presenting information aiming at the targetaudience Identifying the main scope of a research project References and reference management(EndNote software) Data base search Basic rhetoric for poster presentations References Ethics inpublication Arbetsformer : Lectures, seminares, writing exercises, group assignments and practical exercises. As partof the learning process, the Ph.D students will be members of inclass review groups, giving feedback totheir colleagues.Examination : 1) Written assignments reflecting the learning goals of the course: draft for scientific andpopular science paper, poster, electronic poster, and abstract. 2) Evaluation sessions, where the PhDstudents give each other feed back on the written assignments as a part of the learning process 3) Posterpresentation, where the PhD students present their posters to another course participant (there are nopresentations in front of a larger group)Obligatoriska moment : Lectures, workshops, evaluation sessions, and group assignments as well as allwritten assignments. Absence can be compensated: a) during next years course b) individual assigments Antal studenter : 18 20Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to LATER registration date)Övrig information : Welcome to apply for the Ph. D. writing course 2618 on Scientific and popular sciencewriting! <p> During the course, you will have the opportunity to write a draft for a scientific manuscript, anabstract, a popular science article, a press release, and to design a poster. The popular science writing isused as a tool for finding the core of your research project, poster design and presentations. <p> Thecourse also covers: presentation techniques for presenting your poster at a conference, how to answer thereviewer's questions, letter to the editor, review article, cover letter, and ethics in publication. New Ph.D.students are given priority to the course, as we believe that writing is an essential skill that should beacquired as soon as possible during your time as a doctoral student. However, students who have alreadypublished articles will benefit as much from the course as newly registered students, as you write aboutyour own research projects, starting on your own level, and in your own pace. The course curriculum takesinto consideration that all students have different background knowledge and are on different stages oftheir doctoral education. In order to participate in the course, you need either some preliminary data fromyour own research project or other data provided by your supervisor to work with. Our intention is that youshould be able to use everything you write and design during the course: this will keep motivation high andmake sure that you are spending your time in the best possible way. <p> Please address all questions toAnna Hildenbrand Wachtmeister: [email protected] Cellphone: 0707890607 <p> We are lookingforward to meeting you in the course!
Kursansvarig :
Anna Hildenbrand WachtmeisterInstitutionen för kvinnors och barns hä[email protected]
Kontaktpersoner : Anna Hildenbrand WachtmeisterInstitutionen för kvinnors och barns hä[email protected]
Lalit KumarInstitutionen för kvinnors och barns hälsa
Title : Brain circuits
Kursnummer : 2624Antal högskolepoäng : 1.5Datum : 20150907 20150911Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of NeuroscienceSärskild behörighet : Kursens lärandemål : By the end of the course the student shall be able to: Explain the structure andfunction of main neuronal circuits in the brain. Describe the principles for excitatory and inhibitorynetworks, including receptors and neurotransmittors, as well as the action of different chemicalneuromodulators. Describe principles, use and readout of optogenetics and recording technologies. Describeprinciples of viral labeling and tracing of neuronal circuits. Explain how dysfunctions of networks canmanifest as neuropsychiatric disorders. Describe animal behavior tests probing specific networks andnetwork functions.Kursens innehåll : The course will cover the organization and function of main circuits in the brain,including the interaction and participation of different cell types, the interplay between excitation andinhibition, and how circuit output result in behavior. Different techniques for labeling and manipulation ofneuronal circuits will be discussed, including molecular targeting, optogenetics and transsynaptic viraltracing. The connection between deficient circuit functions and neuropsychiatric disorder will be included, aswell as animal behavior tests probing specific circuits and circuit (dys)functions. Specific emphasis will beput into describing the technologies currently used in the neuroscience field.Arbetsformer : Lectures by invited experts and group exercises.Examination : The student should in discussions and a seminar presentation demonstrate the ability tocritically evaluate original research papers on the topics covered and be able to show that the intendedlearning outcomes for the course are reached. Obligatoriska moment : The seminar presentations are obligatory. Antal studenter : 16 28Urval av studenter : We welcome highly motivated applicants from all areas of neuroscience. Basicknowledge of how neurons function and of brain anatomy is a prerequisite to benefit from the course. Selection will be based on 1) the relevance of the course syllabus for the applicant's doctoral projectaccording to the written motivation in the application, 2) date for registration as a PhD student (prioritygiven to earlier reg. date), 3) Experience of neuroscience research as stated in the written motivation. Övrig information : The course will be given in lecture hall Tellus, Department of Neuroscience, Scheelesväg 1, Karolinska Institutet, Solna. Time: 9.0017.00 Monday to Friday. Invited teachers are internationalscientists with important contributions to and expertise in their respective fields, often involvingdevelopment or application of novel technologies. Confirmed speakers: Karl Deisseroth Stanford University,Peter Magill University of Oxford, Daniel Huber University of Geneva, Menno Witter NTNU Trondheim, LauraBusse University of Tubingen, Ofer Yizhar Wiezmann Institute of Science, Jeremiah Cohen Johns Hopkins,Konstantinos Meletis, Marie Carlén and Gilad Silberberg Karolinska Institutet, and more.
Kursansvarig : Marie CarlenInstitutionen för neurovetenskap08[email protected]
Kontaktpersoner :
Title : Neurodegenerative disorders I From molecule totreatment
Kursnummer : 2629Antal högskolepoäng : 1.5Datum : 20151005 20151009Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Neurobiology, Care Sciences and SocietySärskild behörighet : Kursens lärandemål : The student should after the course: 1) understand cellular processes andmolecular mechanisms of neurodegeneration 2) understand mechanisms of protein turnover, degradationand aggregation 3) based on knowledge of these mechanisms critically be able to evaluate the concept ofconformational disorders and its relevance to the different neurodegenerative disorders 4) have achievedbasic knowledge about epidemiology, symptoms, pathology and current treatments of the most commonneurodegenerative disorders such as Alzheimers disease, Parkinsons disease, amyotrophic lateral sclerosisand multiple sclerosis. 5) In addition, the student should understand how the pathology of these disordersis reflected in their symptoms. 6) Based on this understanding, the student should be able to discuss theeffects of treatments, if they are (or may be) symptomatic or curative. 7) Be able to evaluate the relevanceof different disease models, their advantages and limitations with respect to the clinical picture and to whatis known about disease mechanisms.Kursens innehåll : The course will cover topics related to the degeneration of neural cells, apoptosis andnecrosis as well as the cellular and biochemical reactions to neuronal injury. During the course we will alsopresent and discuss symptoms, diagnosis, pathology, epidemiology, genetics and treatment of the mostcommon neurodegenerative disorders such as Alzheimers disease, Parkinsons disease, amyotrophic lateralsclerosis and multiple sclerosis. Molecular mechanisms of current and future treatment strategies, diseasemodels and their potential will be presented and discussed. In addition, the students may within groupassignments study less common neurodegenerative diseases such as frontotemporal dementia, Lewy bodydisease, ataxias, prion diseases as well as vascular, inflammatory or trauma related causes ofneurodegeneration such as stroke, epilepsy or trauma.Arbetsformer : The course runs day time for 1 week fulltime with lectures by invited scientists, literatureseminars as group assignments, and individual studies.Examination : The examination part includes: the group assignments, the oral presentations by thestudents and the following general discussion between all participants. All students are individuallyassessed.Obligatoriska moment : The group assignments, the oral presentations by the students and the followinggeneral discussion between all participants are compulsory. Students that are absent from these parts willhave to individually submit a written presentation of the subject.Antal studenter : 10 30Urval av studenter : If selection of course participants is necessary, we will prioritize 1) students forwhom the course is mandatory, 2) students with an educational plan encompassing the topics of thecourse, and 3) students close to thesis defence missing course on the topic.Övrig information : The course will be held at Karolinska Institutet, Huddinge.
Kursansvarig : Elisabet ÅkessonInstitutionen för neurobiologi, vårdvetenskap och samhälle08585 838 92 [email protected]
Kontaktpersoner : Helena KarlströmInstitutionen för neurobiologi, vårdvetenskap och samhälle08585 837 [email protected]
Maria RoosInstitutionen för neurobiologi, vårdvetenskap och samhä[email protected]
Title : Neurodegenerative disorders II cellular and molecularmechanisms
Kursnummer : 2630Antal högskolepoäng : 1.5Datum : 20151012 20151016Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Neurobiology, Care Sciences and SocietySärskild behörighet : Kursens lärandemål : The student should: Understand and critically evaluate relevant cellular andmolecular pathophysiological mechanisms of neurodegenerative disorders such as stroke, Alzheimer¿sdisease, frontotemporal dementia, Lewy body disease, Parkinson¿s disease, multiple sclerosis, amyotrophiclateral sclerosis, ataxias, prion diseases, epilepsy and trauma, and the mechanisms of current and/orpossible future treatments. Understand and be able to perform the common assays of cell degeneration,and discuss the results, taking into account the limitations of the assays. Be able to discuss the presentdisease models, propose alternative models, and critically evaluate these models from the perspectives ofa) clinical picture, b) disease mechanisms, and c) treatment mechanisms. Kursens innehåll : The course is a continuation of the course Neurodegenerative disorders ¿ Frommolecule to treatment, but it can also be taken as a separate course, provided the participant has in otherways achieved the learning outcomes of that course. The course addresses topics in basic and clinicalresearch on neurodegenerative disorders, with a particular focus on the cellular and molecular mechanisms.The focus will be on a deeper understanding of cellular and molecular mechanisms, and the techniques tostudy them. Arbetsformer : The course runs daytime for 1 week fulltime with some key lectures by invited scientists,laboratory practicals, literature seminars, and discussions in small groups and the entire class.Examination : Written examination followed by group discussions on the examination questions, and ageneral discussion between all participants.Obligatoriska moment : Laboratory practicals, literature seminars and the exam (including the groupdiscussion after the exam) are compulsory. Students that are absent from literature seminars and/orpracticals will have to submit a written presentation of the subject.Antal studenter : 12 24Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information :
Kursansvarig : Lars TjernbergInstitutionen för neurobiologi, vårdvetenskap och samhälle
Kontaktpersoner : Sophia Schedin WeissInstitutionen för neurobiologi, vårdvetenskap och samhälle
Title : Human physiology an overview
Kursnummer : 2644Antal högskolepoäng : 3.0Datum : 20150914 20150925Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Physiology and PharmacologySärskild behörighet : Kursens lärandemål : The student will after completed course have an overview and understanding ofhow the organ systems of the human body function and interact under normal conditions. The coursecontent will also be possible to use for further studies in a PhD education where knowledge about humanbiology is of value. More specifically, the student will be able to: Demonstrate knowledge about basicfunctions of and interaction between organ systems. Assemble and share information in selected areas. Demonstrate a critical and scientific attitude to literature sources for the different course tasks. Kursens innehåll : Overview of cellular and integrative physiology Basic anatomy and biochemistry Physiology of the nervous system Endocrinology Digestion physiology Cardiovascular physiology Renal physiology, fluid balance, acidbase balance Respiration Arbetsformer : Different learning forms such as problem based learning, lectures and a handson humanlab session. Full time during two consecutive weeks.Examination : To pass the course, the student has to show that the learning outcomes have beenachieved. Assessment methods used are an oral quiz along with a written exam.Obligatoriska moment : The examination tasks and the handson human lab are compulsory. Studentsthat are absent from the oral quiz or the handson lab will have to compensate it in agreement with thecourse organizer. Students that are absent from the exam or do not obtain a passing grade in the firstexamination will be offered a second examination.Antal studenter : 10 30Urval av studenter : Selection is based on 1) the date of admission to doctoral education 2) the relevanceof the syllabus to the doctoral projects of the applicants.Övrig information : Lectures will take place in mornings and afternoons. Most of the lectures will takeplace at von Eulers väg 4a/b, KI Solna. Among the lecturers are Carl Johan Sundberg and JessicaNorrbom.
Kursansvarig : Jessica NorrbomInstitutionen för Fysiologi och Farmakologi
Kontaktpersoner : Charlotte SchönbeckInstitutionen för Fysiologi och Farmakologi
Title : Människans fysiologi en översikt
Kursnummer : 2644Antal högskolepoäng : 3.0Datum : 20150907 20150918Språk : SvenskaNivå : ForskarnivåKursansvarig institution : Department of Physiology and PharmacologySärskild behörighet : Kursens lärandemål : Studenten ska efter genomgången kurs ha översiktlig kunskap och förståelse förhur människokroppens organsystem fungerar och samverkar under normala betingelser. Kursinnehållet skakunna användas för fortsatt fördjupning inom en forskarutbildning där vissa humanbiologiska kunskaper ärav värde. Färdigheter Muntligt kunna redogöra för organsystemens funktion. Sammanställa och delgeinformation muntligt och skriftligt för utvalda fördjupningsområden. Förhållningssätt ochvärderingsförmåga Uppvisa ett kritiskt och vetenskapligt förhållningssätt till litteratur som inhämtas förolika fördjupningsuppgifter. Kursens innehåll : Översikt av cellulär och integrativ fysiologi Basal anatomi och biokemi Nervsystemets fysiologi Endokrinologi Digestionsfysiologi Hjärt cirkulationsfysiologi Njurfysiologi,vätskebalans, syrabasfysiologi Respiration Arbetsformer : Kursen innehåller delvis problembaserad undervisning, föreläsningar och en praktisklaboration. Examination : För att bli godkänd i kursen måste studenten visa att lärandemålen har uppnåtts. Dettabedöms genom en muntlig dugga och en skriftlig tentamen. Obligatoriska moment : Moment som är obligatoriska är examinationsuppgifter och praktisk laboration.Vid eventuell frånvaro vid muntlig dugga eller laboration kompenseras detta i överenskommelse medkursens koordinator. I anslutning till kursen ges ett resttentamenstillfälle. Antal studenter : 10 20Urval av studenter : Urval sker utifrån 1) datum för doktorandregistrering (där tidigareregistreringsdatum har förtur) 2) utifrån kursplanens relevans för sökandes doktorandprojekt (enligtmotivering). Övrig information : Föreläsningar är fördelade under förmiddag och eftermiddag och äger rum vid KICampus, Solna. Doktorander har en del gemensamma föreläsningar med kursdeltagare från den friståendekursen Människans Fysiologi. Bland föreläsarna finns bland annat Håkan Westerblad och Carl JohanSundberg.
Kursansvarig : Carl J SundbergInstitutionen för Fysiologi och [email protected]
von Eulers väg 8
17177Stockholm
Kontaktpersoner : Charlotte SchönbeckInstitutionen för Fysiologi och Farmakologi
Title : Surgical Techniques in Rat and Mouse
Kursnummer : 2647Antal högskolepoäng : 2.0Datum : 20150921 20150925Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Comparative medicineSärskild behörighet : Passed both Laboratory Animal Science for Researchers Rodents and LagomorphsAND Laboratory Animal Science for Project Directors, OR have a FELASA C certificate.Kursens lärandemål : After the course the participants are expected to be able to: 1. handle pre, peri andpostoperative care of rats and mice, including asepsis and analgesia 2. recognize microsurgery instrumentsand their use 3. set and use a microsurgery microscope 4. use appropriate suture materials 5. catheterizeblood vessels and to collect blood Kursens innehåll : Analgesia and perioperative care, aseptic surgical techniques, basic surgical techniquesincluding instrumentation, suturing and tissue handling, vein and artery cannulation, explorative laparotomyand blood sampling techniques. Rat will be our main animal model during the course (as techniques areeasier to learn in a larger model), but mouse will also be available.Arbetsformer : A minor part of the learning activities are lectures (10%). The laboratory activities accountfor 70 % of the course. The remaining part of learning activities are demonstrations and project work(tutoring available). Examination : Assessment of learning outcomes To satisfactorily complete this course the participantmust: 1) be able to perform a jugular vein cannulation and to perform blood sampling techniques 2) write areport of provided fictive research projects or of participant's own research projectObligatoriska moment : The presence of participants is required during all scheduled moments. Absenceto lectures can be compensated by a written task. The laboratory moments are compulsory. A retakemight be offered at the next course. Antal studenter : 10 16Urval av studenter : The course offers very few places and only applications from PhD students registeredat Karolinska Institutet will be considered. The relevance of microsurgery to the applicants research project,will also be considered.Övrig information : The course will take place at Comparative Medicine Learning Lab in Solna. ProfessorRené Remie from the Netherlands and Professor Michael Axelsson from Gothenburg University, both expertson microsurgery techniques in rodents, are the course leaders. The course is to 95% practical. One weekfull time labs.
Kursansvarig : Dude GigliottiKomparativ [email protected]
von Eulers väg 4a, plan 4
171 77STOCKHOLM
Kontaktpersoner :
Title : Mesenchymal stem cells biology and clinical potential.
Kursnummer : 2652Antal högskolepoäng : 2.0Datum : 20151012 20151016Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department for Clinical Science, Intervention and TechnologySärskild behörighet : None. Kursens lärandemål : After the completed course, the student will be able to describe the basics of stemcell biology and transplantation and a number of novel technologies and approaches in mesenchymal stemcell research and regenerative medicine. The student can demonstrate an interdisciplinary understanding ofcentral concepts in mesenchymal stem cell science and critically evaluate different methods and techniquesused. The student will be able to extract and integrate information from stateoftheart lectures incombination with overview articles and literature searches on the internet within the research field.Kursens innehåll : The course covers key concepts in translational research on mesenchymal stem cellsfrom the laboratory to the patient in the clinic. This includes a general overview of stem cell biology,transplantation immunology, mesenchymal stem cell history, sources, homing and circulation andinteraction with the immune system. Experts will give an advanced summary of the latest events in themesenchymal stem cell field. The student will be required to take an active part, contribute and valuediscussions on ethical dilemmas in the transplantation area and in workshops on relevant topics in themesenchymal stem cellfield. Networking with students and speakers is highly encouraged in this course.Arbetsformer : The pedagogic framing of this course is based on lectures with corresponding reviewpapers. The course includes workshops with illustrative predicaments where the students are required totake an active part in the discussions. Group discussions and workshops will be conducted where thestudents discuss and integrate information from the lectures and review papers. The students prepare andpresent their examination task in a written report that is handed in after the course.Examination : Individual written project report that will be performed and handed in at the end of thecourse. The individual performance of each student will be evaluated separately.Obligatoriska moment : The lectures, workshops and discussions are mandatory. Compensationaccording to the instructions of the course director.Antal studenter : 10 30Urval av studenter : The selection process will be based on a comprehensive assessment of the students: 1. Motivation for the course 2. Topic of their PhD project 3. Years since PhD registrationÖvrig information : The course is coorganised with the Swedish network for Mesenchymal stem cellbiology and is given at Karolinska Institutet in Huddinge. Invited international key experts in themesenchymal stem cell field will lecture at the course. The examination task (written report) will be handedin after the end of the course.
Kursansvarig : Katarina Le BlancInstitutionen för laboratoriemedicin
Kontaktpersoner :
Title : Grounded Theory in Health Research
Kursnummer : 2654Antal högskolepoäng : 3.0Datum : 20151130 20151211Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Clinical Science and Education, SödersjukhusetSärskild behörighet : Kursens lärandemål : At the end of the course the participants should: 1. Be able to describe theexperience of a classroom climate that incorporates principles of respect, mutuality, cooperation,collaboration, and teamwork. 2. Be able to demonstrate understanding of philosophical and practicalunderpinnings of grounded theory. 3. Be able to express understanding of the essential characteristics ofgrounded theory and exploration methodology. 4. Be able to apply knowledge of grounded theory indiscussing rationales for design of grounded theory study. 5. Be able to understand and assess theapplicability of a grounded theory methodology for a particular research problem. 6. Be able to criticallycomment/evaluate strength and weakness of studies(published papers) using grounded theory methodology 7. Be able to implicate grounded theory research findings for practice and future research 8. Be able todesign grounded theory research proposals including: Title, Background, Research question, Study goal andobjectives, Methodology and reasons to choose grounded theory methodology, Study population, Studysample (participants), Sampling method, Sample size, Inclusion and exclusion criteria, Data gatheringtechnique/s, Data analysis method, Limitation, Ethical consideration, Trustworthiness/ Credibility(validity&reliability) Kursens innehåll : The course will provide practical, handson experience in using grounded theoryresearch. Students will gain a knowledge and understanding of main features and the basic characteristicsof grounded theory, the applicability of grounded theory for particular research problems, including those oftheir own original grounded theory research projects; and how to critically appraise appropriateness ofgrounded theory. The teachers will share their experience of grounded theory research method, theapplication of grounded theory in their respective fields and provide advice and consultation on theadvanced use of cuttingedge grounded theory. The course will start with a deep discussion about whatgrounded theory is, the aim of grounded theory and when to use grounded theory. Then teachers willcontinue with key characteristics of grounded theory research, the applicability of grounded theory forparticular research problems, how to conduct a grounded theory study; and evaluation of rigor in thisapproach. Students will learn to evaluate and make comments on published grounded theory studies interms of methodology, data gathering, quality of gathered data, data analysis approach, display of result,study limitation and ethical considerations. Finally implications of grounded theory findings for practice andfuture research will be discussed and students will learn to design a grounded theory research proposal intheir respective fields. Arbetsformer : The learning activities of the course are a mix of lectures, discussions, individual and groupactivities; interviews, seminars, field observations and individual and group presentations.Examination : The course assessment will include formative and summative assessments. The formativeassessment (50%) will be made through Peer learning Activity, critic a grounded theory paper, individualand group presentations, while the summative assessment (50%) will be through a written examination,and individual qualitative data gathering and analysis and finally a written grounded theory proposal in theirrespective fields. In this way, the students are examined with both groupwise and individual presentations.Obligatoriska moment : Active participation in the class discussions, individual and group assignments(individual and group data gathering by interviews and field observations and data analysis), writtenassignment (a complete grounded theory proposal) and student presentations are mandatory.Compensation according to the instructions of the course director, which means absentees less than 2lectures is acceptable and should be compensated by individual projects related to absentee¿s session.Antal studenter : 10 30Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : The course is held at Department of Clinical Science and Education at Södersjukhusetin Stockholm.
Kursansvarig : Hamid KhankehInstitutionen för klinisk forskning och utbildning, Södersjukhuset
Sjukhusbacken 10118 83
Stockholm
Kontaktpersoner : Jeanette Brynholt OhrmanInstitutionen för klinisk forskning och utbildning, Södersjukhuset08[email protected]
Title : Introduktionskurs i R datahantering, analys och grafiskpresentation
Kursnummer : 2657Antal högskolepoäng : 1.5Datum : 20151105 20151127Språk : SvenskaNivå : ForskarnivåKursansvarig institution : Department of Laboratory MedicineSärskild behörighet : Grundläggande statistikkunskaper (motsvarande "Grundläggande kurs i medicinskstatistik")Kursens lärandemål : Efter kursen ska doktoranden kunna använda R för datahantering, statistisk analysoch grafisk presentation av data. Man ska också kunna installera nya funktioner i R. Kursens innehåll : R är ett kraftfullt program/programspråk för analys och grafisk presentation av data. Rär helt kostnadsfritt och i de flesta ett fullgott alternativ till kommersiella statistikprogram. Programspråketär helt textbaserat vilket gör det svårare att komma igång med jämfört med program som har ett grafisktgränssnitt. När man behärskar det ger det dock en större flexibilitet, bättre kontroll över analyserna och enautomatisk dokumentation av utförda analyser. Kursens fokus ligger på struktur och grundläggandefunktioner i programspråket R. Därutöver presenteras ett urval av funktioner för datahantering, statistiskanalys och grafik. De metoder som tas upp är sådana som vanligen används inom klinisk medicinskforskning (t.ex. ttest, chi2test, regressionsanalys, överlevnadsanalys, boxplot, linje, punkt, stapel ochcirkeldiagram). Kursen fokuserar på hur de statistiska metoderna utförs i R och inte t.ex. deras teoretiskabakgrund, användningsområden eller tolkning.Arbetsformer : Föreläsningar och praktiska övningar.Examination : Varje kursdag avslutas med praktiska övningsuppgifter som löses enskilt. Korrektalösningar krävs för godkänd kurs.Obligatoriska moment : Föreläsningar och inlämningsuppgifter är obligatoriska.Antal studenter : 10 20Urval av studenter : Urvalet baseras på 1) kursplanens relevans för den sökandes doktorandprojekt(enligt motivering), 2) datum för doktorandregistrering (där tidigare registreringsdatum har förtur)Övrig information : Kursdatum: 56/11, 13/11, 20/11, 27/11. Egen laptop behövs för de praktiskaövningarna. Kursen hålls vid Karolinska Universitetssjukhuset, Huddinge.
Kursansvarig : Jonatan LindhInstitutionen för laboratoriemedicin08[email protected]
Avd. för klin. farmakologi, C1:68Karolinska universitetssjukhuset Huddinge14186Stockholm
Kontaktpersoner : Marine AnderssonInstitutionen för laboratoriemedicin08585 [email protected]
Title : Metoder för statistisk analys: Från variansanalys tillmultilevel modeling
Kursnummer : 2666Antal högskolepoäng : 4.0Datum : 20151012 20151030Språk : SvenskaNivå : ForskarnivåKursansvarig institution : Department of Clinical NeuroscienceSärskild behörighet : Kursens lärandemål : Efter genomgången kurs ska studenterna kunna använda sig av följande statistiskaanalysmetoder: (1) Variansanalys; (2) Multipel regressionsanalys; (3) Risk och Oddskvoter; (4) Logistiskregression; (5) Cox regression; (6) Faktoranalys; (7) Strukturekvationsmodellering; (8) Multilevel Modeling.Kursens innehåll : De ovan angivna statistiska analysmetoderna.Arbetsformer : Kursen består av föreläsningar och datorövningar. Föreläsningarna kommer att täcka detteoretiska materialet och beskrivas med relevanta exempel. I datorövningarna kommer de olikaanalysmetoderna att användas på givna data. Vid datorövningarna används programmet SPSS.Examination : Kursen examineras genom att studenterna utför de i kursen ingående analysmetodernasamt presenterar och tolkar resultaten från dessa i form av en skriftlig rapport.Obligatoriska moment : Inga obligatoriska moment.Antal studenter : 15 25Urval av studenter : Urvalet baseras på 1) kursplanens relevans för den sökandes doktorandprojekt(enligt motivering), 2) datum för doktorandregistrering (där tidigare registreringsdatum har förtur)Övrig information : Datum med undervisning: 8/10; 14/10; 15/10; 19/10, 22/10; 27/10; 29/10; Vi hållertill i Huddinge; En stor del av undervisningen finns tillgänglig på nätet.
Kursansvarig : Kimmo SorjonenInstitutionen för klinisk neurovetenskap
Kontaktpersoner : Miriam Entesarian MatssonInstitutionen för neurobiologi, vårdvetenskap och samhälle
Title : Evidensbaserad verksamhet inom hörsel, öron, språk ochtal
Kursnummer : 2668Antal högskolepoäng : 4.5Datum : 20150901 20151218Språk : SvenskaNivå : ForskarnivåKursansvarig institution : Department for Clinical Science, Intervention and TechnologySärskild behörighet : Kursens lärandemål : formulera och motivera en klinisk/motsvarande forskningsfråga inom verksamhetoch forskningsfälten hörsel, öron, språk eller tal självständigt söka information i primära och sekundärainformationskällor och granska informationen kritiskt i enlighet med utvald evidenshierarki eller kriterier redogöra för och beräkna power samt visa förmåga att analysera effektstyrka reflektera över betydelseoch konsekvenser för verksamheten samt förmedla dessa presentera, diskutera och argumentera förtillvägagångssätt och resultat skriftligt och muntligtKursens innehåll : Kursdeltagarens kliniska/annan erfarenhet och nuvarande forskningsområde ligger tillgrund för formulering av en forskningsfråga inom området. Kritisk granskning av befintlig evidenssammanställs och analyseras med relevanta statistiska metoder. Resultatet bearbetas för skriftlig ochmuntlig presentation för olika målgrupper (t ex forskare, kliniker samt målgrupp i det omgivandesamhället).Arbetsformer : Föreläsningar i metod och statistik, eget arbete och gruppövningar i granskningsprocessen,handledning samt seminarierExamination : Samtliga lärandemål examineras genom den skriftliga och muntlig rapporteringen.Obligatoriska moment : Seminarier. Form för kompensation av ev frånvaro beslutas i samråd medkursansvarigAntal studenter : 2 8Urval av studenter : Urvalet baseras på 1) kursplanens relevans för den sökandes doktorandprojekt(enligt motivering), 2) datum för doktorandregistrering (där tidigare registreringsdatum har förtur)Övrig information : Forskarutbildningskursen ges parallellt som kurs på avancerad nivå (då med annankursplan och annan examinationsuppgift).
Kursansvarig : Ellika SchallingInstitutionen för klinisk vetenskap, intervention och [email protected]
Kontaktpersoner : Christina HedestedtInstitutionen för klinisk vetenskap, intervention och teknik
Title : Tumor microenvironment
Kursnummer : 2671Antal högskolepoäng : 1.5Datum : 20151123 20151127Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of OncologyPathologySärskild behörighet : Kursens lärandemål : After completion of the course, the students will be able to describe and discuss thetumor microenvironment and how it contributes to the carcinogenic process.Kursens innehåll : The course is designed for PhDstudents with an interest in tumor biology. It consistsof lectures and experimental demonstration. The course will specifically address the concepts of tumorassociated fibroblasts and macrophages, hypoxia, tumor metabolism, metastasis and tumor vascularangiogenesis and lymphangiogenesis. Experimentally, students will be able to describe the advantages andpitfalls of laser dissection.Arbetsformer : The course will be organized with a series of lectures, experimental demonstration, groupdiscussion and examination at the final day.Examination : To pass the course the learning outcomes of the course must be reached. This will beevaluated individually during the group discussion and based on the written exam.Obligatoriska moment : Antal studenter : 20 25Urval av studenter : Selection of students will be based on personal motivation and the relevance of thecourse content for their research. Priority will be given to registered doctoral students at KI. If necessary, afurther selection will be based on the date for registration as a doctoral student.Övrig information : The course will be held at CCK lecture Hall, R8:00, Karolinska University Hospital,Solna.
Kursansvarig : Yujuan ZhengInstitutionen för onkologipatologi
Kontaktpersoner : Teresa FrisanInstitutionen för cell och molekylärbiologi08[email protected]
Berzelius väg 35
S17177Stockholm
Title : Introduction to teaching at KI
Kursnummer : 2686Antal högskolepoäng : 1.0Datum : 20150902 20151007Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Learning, Informatics, Management and EthicsSärskild behörighet : Kursens lärandemål : At the end of the course we expect you to: Be able to explain general aspects ofhow to facilitate student learning in different teaching situations Be able to reflect upon own teachingexperiences and use educational concepts in a discussion about teaching and learning Kursens innehåll : During the course we will discuss and elaborate on practical issues regarding teachingand learning in laboratory, seminars and lectures. We will discuss and work with ways to challenge studentsand what to do to facilitate their learning. Course participants will observe (auscultate) teaching and reflectupon their experiences. We will touch upon the role of the teacher and KI teaching policies as well asstrategies for coping with stress.Arbetsformer : The course is designed to promote active learning and a variety of teaching and learningstrategies will be used during the course. Examples are lectures, small group discussion, peer teaching,group work, literature studies, auscultation of teaching and reflection in groups. Examination : To satisfactorily complete this course you must demonstrate that you have reached thelearning outcomes by orally presenting your reflections of literature studies and auscultation of teaching. Obligatoriska moment : The assessment seminar the last day of the course is mandatory. If absent, thestudent need to present his/her knowledge at a separate occasion.Antal studenter : 15 30Urval av studenter : Priority will be given to doctoral students who have just started or soon will beinvolved in teaching and that have no teacher training.Övrig information : The course is scheduled 2 September, 15 September and 7 October. In addition, timefor reading and auscultation must be planned by the course participants.
Kursansvarig : Juha NieminenInstitutionen för lärande, informatik, management och etik
Kontaktpersoner : Ingrid SmedbergInstitutionen för lärande, informatik, management och etik08524 837 [email protected]
Title : Multidisciplinary perspectives on active ageing research
Kursnummer : 2688Antal högskolepoäng : 4.5Datum : 20150921 20151217Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Neurobiology, Care Sciences and SocietySärskild behörighet : Kursens lärandemål : The students shall be able to: Theorize on complexity of research directed towardsolder people, and reflect on methodological challenges in ageing research Analyse research on ageing froma multidisciplinary perspective within the framework of different ageing theories Critically judge andhypothesize on research questions within the field of ageing from different disciplinary viewpoints Kursens innehåll : To reach the intended learning outcomes, the course will be built on the researchprojects of the students involved. Definitions and concepts relevant for the focus of those projects will bepenetrated to make students aware of their own frame of reference and of the theory that forms a base fortheir research design. The course will include an overview of current ageing research issues withindifferent professional and scientific domains in health, covering the four levels health promotion, preventionof disease and disability, rehabilitation and preservation of function. A focus on a persons resources fordeveloping an active life, and their possible implications in research will be analysed.Arbetsformer : Lectures, seminars, study of and group discussions on scientific literature and individualwork based on each student's research project.Examination : The students will be examined at a seminar, where a written assignment related to thestudents research project will be presented, discussed and evaluated. The paper should include an attemptto apply the perspective of empowerment as well as a multidisciplinary approach on the project. Obligatoriska moment : Active participation in the seminars, which are mandatory. Absence from aseminar must be compensated by means of a written task, suggested by the course leader.Antal studenter : 15 20Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) the usefulness for the applicant's future research.Övrig information : The dates for the course meetings are September 21, October1213, December 1617, from 9.0016.00. The meetings will take place in Flemingsberg, Alfred Nobels allé 23. Doctoral studentsfrom various disciplines are welcome to apply.
Kursansvarig : Elisabeth RydwikInstitutionen för neurobiologi, vårdvetenskap och samhälle
Kontaktpersoner : Miriam Entesarian MatssonInstitutionen för neurobiologi, vårdvetenskap och samhälle
Elisabeth RydwikInstitutionen för neurobiologi, vårdvetenskap och samhälle
Title : Basic Laboratory Safety
Kursnummer : 2690Antal högskolepoäng : 1.8Datum : 20151109 20151116Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Microbiology, Tumor and Cell BiologiSärskild behörighet : Experience of and/or education in laboratory workKursens lärandemål : After successfully completing this course you as a student should be able toevaluate the risks associated with experiments in the laboratory. The hazards could originate fromchemicals, microbiological agents, cell cultures and human blood/tissues. You should also be able to identifythe needs for suitable personal protective equipment, routines for waste management and transport. Inaddition, you should be familiar with the regulatory framework that governs these topics, the basic needs ofa safe laboratory, and be able to identify the chain of responsibilities.Kursens innehåll : The course aims at giving theoretical and practical knowledge on chemical andbiological aspects of laboratory safety. Topics will deal with writing risk assessments, chemical health risksincluding allergy, cancer and flammable agents, handling and storage of dangerous chemicals, handling ofmicroorganisms and cell cultures including human blood and tissue samples, laboratory acquired infections,biosafety measures including personal protection devices, ventilated workplaces, genetically modifiedmicroorganisms, biosecurity and dual use, transport of dangerous goods, waste management and thesustainable laboratory.Arbetsformer : The information will be given as lectures, group discussions, practical sessions, webtutorials and computer sessions during a total of six days.Examination : The examination is based on an individual written examination and performance of anapproved risk assessment.Obligatoriska moment : Presence during some activities, like introduction, group discussions, practicalsessions and examination, is compulsory according to schedule. Students can not compensate for absenceduring compulsory activities, but are referred to coming courses for these activities.Antal studenter : 30 42Urval av studenter : Selection will be based on 1) date for registration as a doctoral student (prioritygiven to earlier registration date), 2) the relevance of the course syllabus for the applicants doctoral project(according to written motivation).Övrig information :
Kursansvarig : Roland MöllbyInstitutionen för mikrobiologi, tumör och [email protected]
Kontaktpersoner : Ingela DjupedalUniversitetsförvaltningen
Åsa BelinInstitutionen för mikrobiologi, tumör och cellbiologi
Anne EklöfInstitutionen för mikrobiologi, tumör och cellbiologi
Title : Basic Laboratory Safety
Kursnummer : 2690Antal högskolepoäng : 1.8Datum : 20150928 20151005Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Microbiology, Tumor and Cell BiologiSärskild behörighet : Experience of and/or education in laboratory workKursens lärandemål : After successfully completing this course you as a student should be able toevaluate the risks associated with experiments in the laboratory. The hazards could originate fromchemicals, microbiological agents, cell cultures and human blood/tissues. You should also be able to identifythe needs for suitable personal protective equipment, routines for waste management and transport. Inaddition, you should be familiar with the regulatory framework that governs these topics, the basic needs ofa safe laboratory, and be able to identify the chain of responsibilities.Kursens innehåll : The course aims at giving theoretical and practical knowledge on chemical andbiological aspects of laboratory safety. Topics will deal with writing risk assessments, chemical health risksincluding allergy, cancer and flammable agents, handling and storage of dangerous chemicals, handling ofmicroorganisms and cell cultures including human blood and tissue samples, laboratory acquired infections,biosafety measures including personal protection devices, ventilated workplaces, genetically modifiedmicroorganisms, biosecurity and dual use, transport of dangerous goods, waste management and thesustainable laboratory.Arbetsformer : The information will be given as lectures, group discussions, practical sessions, webtutorials and computer sessions during a total of six days.Examination : The examination is based on an individual written examination and performance of anapproved risk assessment.Obligatoriska moment : Presence during some activities, like introduction, group discussions, practicalsessions and examination, is compulsory according to schedule. Students can not compensate for absenceduring compulsory activities, but are referred to coming courses for these activities.Antal studenter : 30 42Urval av studenter : Selection will be based on 1) date for registration as a doctoral student (prioritygiven to earlier registration date), 2) the relevance of the course syllabus for the applicants doctoral project(according to written motivation).Övrig information :
Kursansvarig : Roland MöllbyInstitutionen för mikrobiologi, tumör och [email protected]
Kontaktpersoner : Ingela DjupedalUniversitetsförvaltningen
Åsa BelinInstitutionen för mikrobiologi, tumör och cellbiologi
Anne EklöfInstitutionen för mikrobiologi, tumör och cellbiologi
Title : Measuring physical activity with focus on wearable
monitors applications for clinical and epidemiological studies
Kursnummer : 2693Antal högskolepoäng : 3.0Datum : 20151023 20151123Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Neurobiology, Care Sciences and SocietySärskild behörighet : Kursens lärandemål : The primary objective of the course is to promote high quality research in clinicaland epidemiological studies through understanding of principles for measuring physical activity andmethods for analyzing physical activity data. By the end of the course the student should be able to: 1.Reflect on the concepts relevant for the relation between physical activity and health and understandmeasurement principles for assessing these concepts and especially the principles of of wearable monitorssuch as accelerometry. 2. Choose and justify the best method of choice for assessment of physical activityin accordance with different research questions, study designs and populations. 3. Apply the best method ofchoice for assessment of physical activity in relation to a specific research question. 4. Design a validationor calibration study in clinical and/or epidemiological studies in different populations. 5. Analyse physicalactivity data and interpret the outcomes in accordance with different research questions, study designs andpopulations. Kursens innehåll : Assessment of physical activity using questionnaires and wearable monitors indifferent types of studies Sensor development and measurement principles Calibration and validation Different approaches handling and analyzing the data and outcomes Statistical considerations Interpretation of results Arbetsformer : The course has the primary focus on measurement of physical activity using accelerometryand its use in clinical and epidemiological studies. An overview of other methods to measure physicalactivity such as questionnaires, heart rate monitoring or a combination of different physiological measureswill also be covered. The course is based on demonstrations, workshops and seminars in combination witha few lectures in order to promote a reflective, analytical and critical approach towards this research field.Students will be encouraged to be interactive in demonstrations, workshops and seminars. There will behandson experience with students wearing accelerometer throughout a week and opportunities forexploring, processing and analysis this data. Examination : The learning outcomes will be examined by a written assignment were the students applythe course content to their own doctoral projects. The written assignments will be presented and discussedin a seminar where the students are respondents and opponents on each other¿s work. After the seminarthe students will be given one week to refine their work based on the feedback they are given.Obligatoriska moment : Active participation in workshops and seminars. Absence from a seminar must becompensated by means of a written task, suggested by the course leader.Antal studenter : 15 24Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : The course is given in English. Localities will be KI Campus Huddinge, Alfred NobelsAlle 23. Course days are planned to Oct 23, Nov 24th and an examination day Nov 23. There will beassignments to do during the period of the course. The platform PingPong will be used for online learning,discussions and documents. The course consist of lectures, lab and seminars. Professor Malcom Granat,Professor Ulf Ekelund and Associate Professor Örjan are invited lecturers.
Kursansvarig : Maria HagströmerInstitutionen för neurobiologi, vårdvetenskap och samhälle08[email protected]
Kontaktpersoner :
Title : Metoder för systematisk litteraturöversikt
Kursnummer : 2704Antal högskolepoäng : 7.5Datum : 20150907 20151215Språk : SvenskaNivå : ForskarnivåKursansvarig institution : Department of Clinical NeuroscienceSärskild behörighet : Kursens lärandemål : Efter avslutad kurs förväntas deltagarna: *kunna reflektera över vilket bidrag denegna forskningsöversikten tillför kunskapsfältet och identifiera frågor som kvarstår *ha utvecklatfärdigheter i användandet av forskningssyntes som en vetenskaplig process *kunna kritiskt utvärderaprocedurer vid systematiska litteraturöversikterKursens innehåll : Utveckla färdigheter att: *använda systematiskt tillvägagångssätt och att sammanfattakunskap utifrån en vetenskaplig process *reflektera över hur den valda frågeställningen inom ramen föravhandlingsarbetet bidrar till kunskapsbasen inom aktuellt forskningsområde Centralt i kursen är attutveckla färdigheter att använda systematiskt tillvägagångssätt och att sammanfatta kunskap utifrån envetenskaplig process. Olika syften och metoder för forskningsöversikter exemplifieras. Processen i ensystematisk litteratur översikt karaktäriseras av en tydligt formulerad fråga som besvaras genomsystematiska och explicita metoder för att identifiera, välja ut, kritiskt bedöma och analysera relevantastudier utifrån frågeställningen. Arbetsformer : Kursen tillhandahåller en introduktion i metoder för systematisk litteraturgenomgång. Kursdeltagaren utvecklar ett protokoll för och genomför en systematisk litteraturgenomgång som fokuserarpå en valfri komponent/aspekt som kommer att appliceras i deltagarens eget avhandlingsarbete. Kritisktbedöma och diskutera svagheter och styrkor i det egna och kursdeltagarnas protokoll och översikter(reviews). Kursen är en distanskurs på deltid som omfattar tre till fyra tillfällen om 12 dagar varav ett ärslutseminarium. Under kursen varieras arbetsformerna med t.ex. föreläsningar, eget arbete, granskning avandras arbete och gruppdiskussioner, för att kursdeltagarna utifrån denna erfarenhet ska kunna reflekteraöver hur kunskapen inom det egna forskningsfältet byggs upp. I kursen får deltagarna prova på att arbetasystematiskt utifrån principer om forskningssyntes och även bearbeta och kritiskt granska olika procedurerför forskningsöversikter. Vid första tillfället diskuteras frågeställningen och hur den valda komponenteninom ramen för det egna avhandlingsarbetet kan användas i studentens egna forskning. Till andra tillfälletgörs en individuell skriftlig plan eller protokoll för hur man implementerar en systematisk forskningsöversiktutifrån frågeställningen om den valda komponenten (23 sidor, 1,5 radavstånd, 12 punkter Times, Roman).Uppgiften skickas i form av ett word dokument (döpt med ditt namn). Examination : Kursen examineras individuellt genom muntlig och skriftlig examination i form av ensystematisk forskningsöversikt. För godkänd kurs krävs att lärandemålen är uppfyllda, vilket innebärgodkänt resultat på den skriftliga examinationen samt aktivt deltagande i obligatoriska delar. Examinationen består av: 1) En individuell uppsats i formen av en systematisk översikt och består av enlitteratur genomgång utifrån den valda frågeställningen (812 sidor, 1,5 radavstånd, 12 punkter TimesRoman Fokus i den sista uppgiften kommer att vara på: a) hur kursdeltagaren har undersökt ochsammanfattat den valda frågeställningen i den individuellt genomförda forskningssyntesen b) hurstudenten, i en metoddiskussion, har kritiskt granskat procedurer i den egna systematiska genomgången 2) Aktivt deltagande i det sista seminariet, där den individuella uppgiften (punkt 1) presenteras ochdiskuteras. Examination för kursen kommer att tillhandahållas under ett år efter kursens slut. Obligatoriska moment : Deltagandet i slutseminariet är obligatoriskt. Frånvaro från det sista seminarietska kompenseras med en skriftlig kritisk diskussion av en annan students skriftliga rapport till det sistaseminariet.Antal studenter : 15 20Urval av studenter : 1. Doktorander i Forskarskolan i vårdvetenskap har företräde över andra sökanden.<br /> 2. Doktorander har företräde över andra sökanden<br /> 3. KI doktorander har företräde överandra doktorander<br /> 4. Motivering Övrig information : Kursen är en distanskurs på deltid som omfattar fem till sex tillfällen om 12 dagarvarav ett är slutseminarium.<br /> Tider och lokal<br /> Tillfälle 1: 7 september, 9.0016.00<br /> Tillfälle 2: 8 september, 9.0016.00<br /> Tillfälle 3: 9 september, 9.0016.00<br /> Tillfälle 4: 1 oktober,9.0016.00<br /> Tillfälle 5: 5 november, frivillig handledning, OBS detta datum kan komma att ändras isamråd med er!<br /> Tillfälle 6: (detta sker i halvklass och ni kommer att närvara en av de två dagarna):14 eller 15 december, 9.0016.00<br /> Samtliga tillfällen är på Solna campus.<br /> <br /> De två förstatillfällena består av föreläsningar och hjälp att starta upp ert egna arbete. Föreläsare under dessa dagar ärAgneta Pettersson, (projektledare från SBU, Statens beredning för medicinsk utvärdering), YvonneWengström (Karolinska Institutet) och Petter Gustavsson (Karolinska Institutet). Vid tillfälle tre får nipersonlig hjälp i bibliotekets lokaler av bibliotekets kunniga personal. Dessa tre tillfällen är viktiga för attkomma igång med arbetet. <br /> <br /> Kontaktperson: Ann Rudman
Kursansvarig : Ann RudmanInstitutionen för klinisk neurovetenskap073[email protected]
Kontaktpersoner : Miriam Entesarian MatssonInstitutionen för neurobiologi, vårdvetenskap och samhälle
Title : Hematopoiesis and hematopoietic stem cells in health anddisease
Kursnummer : 2717Antal högskolepoäng : 2.0Datum : 20151026 20151030Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Medicine, HuddingeSärskild behörighet : NoneKursens lärandemål : After the completed course, the student will be able to describe the basics ofhematopoietic stem cell development, stem cell transplantation, development of different types of leukemiaand a number of novel technologies and approaches for hematopoietic stem cell research and clinicaltreatment. The student will be able to demonstrate an interdisciplinary understanding of central concepts inhematopoietic stem/progenitor cells, regulation of hematopoiesis, engraftment and immunological aspectsof stem cell transplantion and critically evaluate different methods and techniques used. The student will beable to extract and integrate information from stateoftheart lectures in combination with overviewarticles and literature searches on the internet within the research field. Kursens innehåll : The course covers key concepts in hematology from the laboratory to the patient in theclinic. This includes visits to hematology clinic including bone marrow sampling and ward round as well aslaboratory demonstration. There will be a general overview of hematology including development of fetaland adult hematopoiesis, molecular regulation of hematopoiesis, leukemic stem cells, immunologicalconsideration in stem cell transplantation, future treatment, stem cell homing and summary of the latestevents in the normal development of hematopoiesis as well as development and treatment of hematologicaldisorders including myeloid and lymphoid leukemia. The student will be required to take an active part,contribute and value discussions on stem cell transplantation. Arbetsformer : The pedagogic framing of this course is based on lectures with corresponding reviewpapers. The course includes workshops with illustrative predicaments where the students are required totake an active part in the discussions. Group discussions/workshop will be conducted where the studentsdiscuss and integrate information from the lectures and review papers. The students prepare and presenttheir examination task in a written report that is handed in after the course.Examination : Individual written project report that will be performed and handed in at the end of thecourse. The individual performance of each student will be evaluated separately. Obligatoriska moment : The lectures and discussions are mandatory. Compensation according to theinstructions of the course director.Antal studenter : 8 30Urval av studenter : The selection process will be based on a comprehensive assessment of the students: 1. Motivation for the course 2. Topic of their PhD project 3. Registration date (priority given to studentswith earlier registration date)Övrig information : The course is given in Huddinge.
Kursansvarig : Julian WalfridssonInstitutionen för medicin, Huddinge
Kontaktpersoner : Julian WalfridssonInstitutionen för medicin, Huddinge
Title : Culture and Brain
Kursnummer : 2721Antal högskolepoäng : 2.0Datum : 20150901 20160215Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Microbiology, Tumor and Cell BiologiSärskild behörighet : Kursens lärandemål : After the course students should be able to describe the interplay between culture(in a wide sense of the word) our brain and health, wellbeing and learning. They shall also be able toexplain different scientific paradigms by which such questions are studied. Specifically, students shall beable to 1) give examples of how experience and performance of culture are perceived by the brain, 2) giveexamples of how culture might be used in prevention, health care and rehabilitation, 3) also give exampleswhere brain and educational science meet and inform each other, 4) discuss possible mechanisms, and 5)propose further studies that will increase and enhance our understanding of the field.Kursens innehåll : Inspired by the fast development in the cross disciplinary field of culture brain health,we will address questions concerning how activities and experiences in different fields of culture (music,literature, fine arts, physical activity etc) are perceived by and affect the human brain in ways that influencewellbeing, health, healing and rehabilitation, and also how processes and plastic structures in braininfluence learning. The course will cover questions such as how brain perceives culture, brain plasticity, useof culture in health care and rehabilitation, and the crossroad between brain and educational research. Thecourse will touch upon a large number of different sorts of culture, and make students familiar withdifferent scientific paradigms in various academic disciplines studying these phenomena, and wide range ofdifferent scientific approaches and techniques. Arbetsformer : In average 12 lectures each month for five months, each immediately followed by aseminar, 23 hrs on each occasion. Lectures and seminars held by internationally leading scientists in thefields, whose work quailify to be presented on the website "Kulturella hjärnan". (www.culturalbrain.se).Every occasion consists of a appr 12 hour seminar/lecture with the invited expert followed by a two houropen discussion, i.e 34 hours on each occassion. For each seminar the students will usually be given atleast one article on the topic to read. Active participation in discussions in groups with invited speaker ofhigh international standards is a key element. You also receive DVDrecordings of all lectures for further selfstudies at home.Examination : On an individual basis. Continuous by workshop discussions. Written homeexam (essay). Obligatoriska moment : The seminars are compulsory. Absence can be compensated for after discussionwith the course leader.Antal studenter : 10 30Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information :
Kursansvarig : Ingemar ErnbergInstitutionen för mikrobiologi, tumör och [email protected]
Box 280, Karolinska Institutet
17177Stockholm
Kontaktpersoner : Bertha BrodinInstitutionen för onkologi[email protected]
Cancer Centrum Karolinska CCK R8:00
171 76Stockholm
Title : Writing skills for science
Kursnummer : 2743Antal högskolepoäng : 1.0Datum : 20150813 20150816Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Cell and Molecular BiologySärskild behörighet : Kursens lärandemål : After the completed course, the students will be able to explain and relate the basiccomponents of a good scientific manuscript in the IMRaD format, and demonstrate knowledge on thedifferent linguistic strategies for constructing sentences and paragraphs for improved readability and flow inscientific manuscripts and other communications. Kursens innehåll : The course consists of two major parts: 1) A creative writing workshop focusing on theuse of creative writing techniques for improved communication in science and in general, and in using textas a tool in communication. The creative writing workshop includes writing exercises and readings anddiscussions. 2) A scientific writing workshop on writing IMRaD style articles including exercises in analysingthe structure of published papers. The workshop includes perspectives from an editor's point of view aboutfactors affecting rejection or acceptance of a paper.Arbetsformer : The course includes presentations, readings, writing exercises and text analysis exercises. Examination : The students will be examined on the basis of their active participation in individualexercises (writing exercises and IMRaD style article analysis). Obligatoriska moment : The writing and text analysis exercises and readings are obligatory. Absencefrom compulsory parts is compensated according to the instructions from the course directors.Antal studenter : 10 15Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : This writing course is organised as an intensive weekend camp at Solvik. Participantswill be able to enhance their creative and professional writing skills with instructors from Harvard MedicalSchool, Uppsala University and Karolinska Institutet in a relaxed small group setting. The course is free ofcost with basic summer camp food. The participants will live in shared accommodation and must bring theirown bed linen and towels. Solvik is located in a beautiful archipelago setting in Värmdö, just half an hourfrom central Stockholm with public transport from Slussen.
Kursansvarig : Matti NikkolaInstitutionen för cell och molekylärbiologi
Kontaktpersoner :
Title : The Developing Brain
Kursnummer : 2780Antal högskolepoäng : 1.5Datum : 20150831 20150904Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of NeuroscienceSärskild behörighet : Kursens lärandemål : By the end of the course the student shall be able to describe the major stepscontributing for the development of the brain and transfer new knowledge acquired in the course into theirspecific projects or fields of research. The student should be able to explain basic principles behind neuraldevelopment such as patterning, specification from neural stem cells to neurons and oligodendrocytes,migration, neurite outgrowth, axon pathfinding, synapse formation, neuroglia interactions, the role ofneuronal activity, and regeneration final circuit integration. Describe key concepts such as epigenetic states,cell potency and faterestriction, transcriptional programs. To apply and understand the readout of modernmethods of probing developmental questions including inducible genetic fatemapping, manipulation andtissue culture systems in different animal model systems as well as transcriptomic analysis. Kursens innehåll : The course will cover the main developmental steps for creating the mature circuits inthe brain, including the patterning of the neural plate and thus the origin of cell types, the interplaybetween intrinsic and extrinsic factors, neuroglia interactions and the role of network activity in shapingthe final circuits. Different molecular and tracing technologies, and model organisms will be covered. Animportant aspect of the course regards molecular technologies for labeling, transcriptional analysis andgenetic manipulation of defined neural populations. Connections between aberrant developmental processesand neurological disorders will be covered.Arbetsformer : Lectures by invited experts, group work, seminar presentations.Examination : The students should demonstrate their knowledge about the items stated as individuallearning outcomes during interaction with invited experts, group work and presentations. They shoulddemonstrate that they can critically evaluate original research papers on these topics in a seminarpresentation and in discussions.Obligatoriska moment : All lectures and the seminar presentation (examination) are compulsory. Studentwho cannot attend will be given the opportunity to perform an individual seminar presentation and takepart in an individual exam.Antal studenter : 12 30Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date) Övrig information : The course is a full time course (09.0016.00) and will be given at the Department ofNeuroscience (Room Tellus, Scheeles väg 1, 5th floor). Confirmed external speakers are: Paola Arlotta,Harvard, USA. Steve Goldman, Rochester Univ, USA. Yevgenia Kozorovitskiy, Northwestern, USA. DenisJaubadon, Univ. Geneva, CH. Eve Seuntjens, GIGANeuroscience, BE.
Kursansvarig : Jens HjerlingLefflerInstitutionen för medicinsk biokemi och biofysik
jens.hjerling[email protected]
Kontaktpersoner : Goncalo CasteloBrancoInstitutionen för medicinsk biokemi och biofysik
Goncalo.Castelo[email protected]
Title : Present your research!
Kursnummer : 2787Antal högskolepoäng : 1.5Datum : 20150831 20151110Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Women's and children's healthSärskild behörighet : NoneKursens lärandemål : The overall aim of the course is to give the Ph.D. student knowledge in presentingresearch results orally with support of visual media like power point slides, whiteboard, flipchart and ascientific poster. After attending the course, the Ph.D. Student should: 1. BE ABLE TO DESIGN AN ORALPRESENTATION IN AN ADEQUATE WAY WITH EMPHASIS ON : a. Setting goals and aims for thepresentation b. Structure of the presentation c. Simplification of research results in order to enhance theunderstanding d. Choice of pictures e. Language f. Adjusting to different presentation types like posterpresentation, grant proposal, and for example your dissertation lecture, or presentation of your researchresults to your research group, or a journal club g. Time management: how much time do I have at mydisposal and how to keep the time limits h. Basic rhetoric and presentation techniques 2. BE ABLE TODESIGN AND USE SUPPORTIVE MEDIA FOR A SUCCESSFUL PRESENTATION: a. Power Point slides ¿interesting and structured, adjusted to the room conditions and the audience b. Scientific poster ¿illustrative, good flow and conclusive c. Flipchart, whiteboard and other supporting media 3. KNOW THEBASICS ABOUT HOW TO PRESENT (presentation techniques and rhetoric): a. Body language and posture b.Language and pace c. How to prepare yourself for a presentation d. How to remember what you want topresent e. Building confidence (be less nervous) to present f. What to avoid doing during a presentation g.How to deal with questions from the audience 4. HAVE GAINED KNOWLEDGE ON HOW TO INTERACT WITHTHE AUDIENCE: a. Catching the audience¿s attention b. Keeping the audience´s attention for a longerperiod of time c. How to impress your audience d. How to address the audience e. Communicating with theaudience f. How to make the audience trust you g. Preparing the presentation with different audiences inmind h. Different learning styles which influences the audience´s attention i. Attention curve of theaudience j. How to enhance the learning of the audience Kursens innehåll : The scope of the course is to design and give oral presentations of your researchresults in different contexts. The main content of the course: 1. DESIGN AND DISPOSITION OF AN ORALPRESENTATION (poster presentation, grant proposal, short presentation of research results): a. Goals andaims b. Structure c. Simplifications to enhance understanding d. Choice of pictures e. Language f. Timemanagement: how much time, keeping the time limits 2. PRESENTATION TECHNIQUES AND RHETORICFOR ORAL PRESENTATIONS: a. Body language and posture b. Language and pace c. How to prepareyourself for a presentation d. How to remember what you want to present e. Building confidence (be lessnervous) to present f. What to avoid doing during a presentation g. How to deal with questions from theaudience 3. DESIGN AND USE OF SUPPORTING MEDIA FOR A PRESENTATION: a. Power Point slidesincluding introduction to power point b. Scientific poster c. Flipchart, whiteboard and other supportingmedia 4. INTERACTION WITH THE AUDIENCE: a. Catching the audience's attention b. How to address theaudience c. Keeping the audience´s attention for a longer period of time d. Communicating with theaudience e. How to make the audience trust you f. Preparing the presentation with different audiences inmind g. Different learning styles which influences the audience´s attention h. How to impress your audience i. Attention curve of the audience j. How to ease the learning of the audience 5. PRACTICAL EXERCISES: a. Presenting in front of an audience: i. Grant proposal ii. Poster presentation iii. Presentation of student´schoice b. Presentation exercises in pairs or small groups c. Presenting to different audiences d. Bodylanguage e. Language and pace f. How to use your audience as an asset g. How to interact with youraudience h. How to remember your presentation i. Give an receive feedback on presentations j. Deal withnervousness and stay focused on your presentation k. Video recording of presentation with feedback fromdifferent perspectives Arbetsformer : Lectures, written assignments, workshops, coaching, group work, and practical exercisesin groups and with peer.Examination : Poster presentation including scientific poster, grant proposal presentation, and apresentation of your own choice.Obligatoriska moment : Three complete presentations (designed and presented to the class): q. Posterpresentation including a scientific poster b. Grant proposal presentation c. One presentation of the student´s own choise Antal studenter : 16 18Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : Welcome to apply for Ph.D. course Present your research! The course takes place onthe following days: 31st of August, 1st OR 2nd of September, 22nd of September, 3rd of November, 10th of
November. The reason for giving the course over a longer period of time is to give you a chance to practicethe skills your learn during the course. This course is suitable for anyone that wants to improve his or herpresentation techniques skills; no matter if you are starting off on a beginner's level or if your skills arequite advanced. You will be working together with very experienced teachers, both in groups andindividually, and we will focus on your individual needs. Different approachess and techniques are usedbased on the latest research in the field and we focus a lot on the participant's individual needs in terms ofneeds (aims, nervousness, structure, bodylangugage, voice etc) and different kinds of presentations thatyou might need to give.
Kursansvarig : Anna Hildenbrand WachtmeisterInstitutionen för kvinnors och barns hä[email protected]
Kontaktpersoner : Anna Hildenbrand WachtmeisterInstitutionen för kvinnors och barns hä[email protected]
Title : Present your research!
Kursnummer : 2787Antal högskolepoäng : 1.5Datum : 20150825 20151109Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Women's and children's healthSärskild behörighet : NoneKursens lärandemål : The overall aim of the course is to give the Ph.D. student knowledge in presentingresearch results orally with support of visual media like power point slides, whiteboard, flipchart and ascientific poster. After attending the course, the Ph.D. Student should: 1. BE ABLE TO DESIGN AN ORALPRESENTATION IN AN ADEQUATE WAY WITH EMPHASIS ON : a. Setting goals and aims for thepresentation b. Structure of the presentation c. Simplification of research results in order to enhance theunderstanding d. Choice of pictures e. Language f. Adjusting to different presentation types like posterpresentation, grant proposal, and for example your dissertation lecture, or presentation of your researchresults to your research group, or a journal club g. Time management: how much time do I have at mydisposal and how to keep the time limits h. Basic rhetoric and presentation techniques 2. BE ABLE TODESIGN AND USE SUPPORTIVE MEDIA FOR A SUCCESSFUL PRESENTATION: a. Power Point slides ¿interesting and structured, adjusted to the room conditions and the audience b. Scientific poster ¿illustrative, good flow and conclusive c. Flipchart, whiteboard and other supporting media 3. KNOW THEBASICS ABOUT HOW TO PRESENT (presentation techniques and rhetoric): a. Body language and posture b.Language and pace c. How to prepare yourself for a presentation d. How to remember what you want topresent e. Building confidence (be less nervous) to present f. What to avoid doing during a presentation g.How to deal with questions from the audience 4. HAVE GAINED KNOWLEDGE ON HOW TO INTERACT WITHTHE AUDIENCE: a. Catching the audience¿s attention b. Keeping the audience´s attention for a longerperiod of time c. How to impress your audience d. How to address the audience e. Communicating with theaudience f. How to make the audience trust you g. Preparing the presentation with different audiences inmind h. Different learning styles which influences the audience´s attention i. Attention curve of theaudience j. How to enhance the learning of the audience Kursens innehåll : The scope of the course is to design and give oral presentations of your researchresults in different contexts. The main content of the course: 1. DESIGN AND DISPOSITION OF AN ORALPRESENTATION (poster presentation, grant proposal, short presentation of research results): a. Goals andaims b. Structure c. Simplifications to enhance understanding d. Choice of pictures e. Language f. Timemanagement: how much time, keeping the time limits 2. PRESENTATION TECHNIQUES AND RHETORICFOR ORAL PRESENTATIONS: a. Body language and posture b. Language and pace c. How to prepareyourself for a presentation d. How to remember what you want to present e. Building confidence (be lessnervous) to present f. What to avoid doing during a presentation g. How to deal with questions from theaudience 3. DESIGN AND USE OF SUPPORTING MEDIA FOR A PRESENTATION: a. Power Point slidesincluding introduction to power point b. Scientific poster c. Flipchart, whiteboard and other supportingmedia 4. INTERACTION WITH THE AUDIENCE: a. Catching the audience's attention b. How to address theaudience c. Keeping the audience´s attention for a longer period of time d. Communicating with theaudience e. How to make the audience trust you f. Preparing the presentation with different audiences inmind g. Different learning styles which influences the audience´s attention h. How to impress your audience i. Attention curve of the audience j. How to ease the learning of the audience 5. PRACTICAL EXERCISES: a. Presenting in front of an audience: i. Grant proposal ii. Poster presentation iii. Presentation of student´schoice b. Presentation exercises in pairs or small groups c. Presenting to different audiences d. Bodylanguage e. Language and pace f. How to use your audience as an asset g. How to interact with youraudience h. How to remember your presentation i. Give an receive feedback on presentations j. Deal withnervousness and stay focused on your presentation k. Video recording of presentation with feedback fromdifferent perspectives Arbetsformer : Lectures, written assignments, workshops, coaching, group work, and practical exercisesin groups and with peer.Examination : Poster presentation including scientific poster, grant proposal presentation, and apresentation of your own choice.Obligatoriska moment : Three complete presentations (designed and presented to the class): q. Posterpresentation including a scientific poster b. Grant proposal presentation c. One presentation of the student´s own choise Antal studenter : 16 18Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : Welcome to apply for Ph.D. course Present your research! The course takes place onthe following days: 25th of August, 26th OR 27th of August, 21st of September, 2nd of November, 9th of
November. The reason for giving the course over a longer period of time is to give you a chance to practicethe skills your learn during the course. This course is suitable for anyone that wants to improve his or herpresentation techniques skills; no matter if you are starting off on a beginners level or if your skills arequite advanced. You will be working together with very experienced teachers, both in groups andindividually, and we will focus on your individual needs. Different approachess and techniques are usedbased on the latest research in the field and we focus a lot on the participant's individual needs in terms ofneeds (aims, nervousness, structure, bodylangugage, voice etc) and different kinds of presentations thatyou might need to give.
Kursansvarig : Anna Hildenbrand WachtmeisterInstitutionen för kvinnors och barns hä[email protected]
Kontaktpersoner : Anna Hildenbrand WachtmeisterInstitutionen för kvinnors och barns hä[email protected]
Title : How to conduct systematic reviews and metaanalyses
Kursnummer : 2790Antal högskolepoäng : 3.0Datum : 20151019 20151104Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Molecular Medicine and SurgerySärskild behörighet : Kursens lärandemål : After completion of the course the students should be able to: 1) Independentlyplan and produce a study protocol to perform a systematic review and metaanalysis, including a detaileddescription of the selection of the eligible studies and statistical methodology. 2) Critically reflect on otherstudents individual project work in a scientifically constructive way. 3) Interpret and critically evaluatescientific studies relevant to the course content.Kursens innehåll : The course is designed for PhD students, in particular those who are at an early stageof their research education, and those with an interest in conducting systematic reviews and metaanalysis.The content of the course is as follows: 1) Basic terms in systematic reviews and metaanalyses, 2) How towrite a study protocol for a systematic review, 3) How to perform a systematic literature search, 4) Dataextraction and quality assessment of included studies, 5) Statistical methods used in metaanalyses andinterpretation, 6) Problems and limitations of systematic reviews and metaanalysis, 7) Examination andcourse evaluation. Throughout the course, the students will work on an individual project and will have topeerreview the project of another student. Further, students will critically review and discuss relevantscientific articles.Arbetsformer : Lectures, seminars, individual article review, group discussions, practical sessions (one onsystematic literature search, one on statistical methods) and homework tasks will be used. The coursefocuses on active learning, i.e. putting knowledge into practice and critically reflecting upon the knowledge,rather than memorising facts. Therefore, much of the focus of the course is on the individual project wherestudents are required to develop a full study protocol including several important aspects covered in thelectures, article reviews and group discussions. Students will also peerreview each other¿s projects andthis will form the basis for the final examination seminar.Examination : To pass the course the student must actively participate in the course and pass theexaminations: 1) Individual project work: To develop a written comprehensive yet concise study protocolincluding several important aspects as discussed during the course; 2) Peerreview of other students¿projects followed by an oral presentation of their own project and opposition of other students projectsduring the group examination; 3) Critically review scientific articles relevant to the course content andparticipate actively in the seminars.Obligatoriska moment : Compulsory attendance includes the scheduled lectures and seminars. Absencewill need to be replaced by individual assignments following discussion with the course coordinator, e.g.article reviews, with written or oral followup.Antal studenter : 20 25Urval av studenter : Selection will be based on 1) Date of registration as a PhD student 2) suitability ofPhD project 3) The motivation to attend the course.Övrig information :
Kursansvarig : Nele BrusselaersInstitutionen för molekylär medicin och [email protected]
UGIR Norra Stationsgatan 67
17176Stockholm
Kontaktpersoner : Kalle MälbergInstitutionen för molekylär medicin och kirurgi
Title : Medical developmental biology
Kursnummer : 2794Antal högskolepoäng : 1.5Datum : 20150817 20150821Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of NeuroscienceSärskild behörighet : Kursens lärandemål : After the course the doctoral student is expected to be able: To fully understandand review the basic biology and definitions of embryonic and fetal stem cells, To understand and reviewthe most fundamental genetic and epigenetic/transcriptional regulatory mechanisms guiding thedevelopment of the essential organs, To understand and review the basic principles of regenerativemedicine and perinatal physiology.Kursens innehåll : To achieve a better understanding of embryonic and fetal development, and to providebetter healthcare for newborns and children, it is necessary to understand the development in basicresearch to be able to more rapidly apply such knowledge in clinical care. In this course, worldleadingscientists in the fields of developmental biology, stem cell research, and regenerative medicine, will discussthe molecular mechanisms, cell biology, genetics and epigenetics of development in general and morespecifically in a wide variety of organs, with a particular bias towards human development and disease. Thenature of the course is translational and provide a wide range of knowledge from transcriptionalmechanisms to basic physiology and patient care.Arbetsformer : The course is based on lectures from morning to lunch by prominent lecturers. There arepractical workshops and clinical visits in the afternoons. The course is considered demanding and requiresfulltime presence and attention.Examination : Every student needs to make either a fifteen minute individual presentation or to presenttheir projects by poster presentation. The oral and poster presentations are examined by at least fourcourse leaders and the participants receive immediate feedback directly from the course leaders/examiners.Further feedback is given continuously throughout the course. Every student will be individually assessed.Obligatoriska moment : Full presence is absolutely required. Necessary absence will be regulated withthe course leader and given as extra tasks.Antal studenter : 8 14Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : This is an international exchange course between Karolinska Institutet (KI) andUniversity of Toronto (U of T) on developmental and perinatal biology with a translational focus. It has beenorganised since 1996 and now has over 500 alumni. It takes place every second year in Toronto and everyother second at KI, and 2015 it will take place at KI. In addition to lectures from 20 leading researchers inthe field from KI and Toronto, workshops, and "meet the expert" sessions, there is also an extensive socialprogram to allow the building of new contacts and interactions between the two universities. For 2015, thisprogram includes visits to the Canadian Embassy and City Hall of Stockholm. The course is also closelylinked to the Mats Sundin postdoc fellowship for exchange between KI and U of T. Please note that this is afulltime course.
Kursansvarig : Ola HermansonInstitutionen för neurovetenskap4685248[email protected]
Kontaktpersoner : Ola HermansonInstitutionen för neurovetenskap4685248[email protected]
Title : Introduction to Stata for epidemiologists
Kursnummer : 2796Antal högskolepoäng : 1.0Datum : 20150914 20150915Språk : EngelskaNivå : Doctoral levelKursansvarig institution : The institute of Environmental MedicineSärskild behörighet : Kursens lärandemål : After successfully completing this course you as a student should independently beable to: use Stata to open and describe a dataset import and export datasets in different formats produce tables of descriptive statistics count and present table of counts provide a graphicalpresentation of continuous variables generate new variables and recode existing variables testunivariable associations for continuous and categorical data Kursens innehåll : This course is designed to introduce students to the basics of Stata. It will focus on theminimum set of commands students should know to organize their own work. Specific topics include datamanagement, datareporting, graphics and basic use of dofiles. By the end of this course, the studentshould be capable of using Stata independently. As motivating and instructive examples both lectures andexercises will be based on real studies published in top scientific journals. Arbetsformer : Lectures and computer exercises using Stata®.Examination : Written examination. Students who do not obtain a passing grade in the first examinationwill be offered a second chance to resubmit the examination within two months of the final day of thecourse. Students who do not obtain a passing grade at the first two examinations will be given top priorityfor admission the next time the course is offered.Obligatoriska moment : Examination is compulsory.Antal studenter : 12 25Urval av studenter : Selection according to 1) the relevance of the course for the applicant's project(according to written motivation), 2) date for registration as a doctoral student (priority given to earlierregistration date). Submit a completed application form and give all information requested, including ashort description of current research, motivation for attending and an account of previous courses.Övrig information : The present course covers an introduction to the Stata package and basic commandsfor data manipulation and presentation. The content on how Stata can be used to manage and analyseepidemiological data is not covered.
Kursansvarig : Nicola OrsiniInstitutet för miljömedicin
Kontaktpersoner : Ida Kettley CronfalkInstitutet för miljömedicin
Title : Biostatistics II: Logistic regression for epidemiologists
Kursnummer : 2797Antal högskolepoäng : 2.0Datum : 20151207 20151216Språk : EngelskaNivå : Doctoral levelKursansvarig institution : The institute of Environmental MedicineSärskild behörighet : Knowledge in epidemiology and biostatistics equivalent to "Epidemiology I:Introduction to epidemiology" (course 1577) and "Biostatistics I: Introduction for epidemiologists" (course1579) or corresponding coursesKursens lärandemål : After successfully completing this course you as a student are expected to be ableto: choose a suitable regression model for assessing a specific research hypothesis using data collectedfrom an epidemiological study, fit the model using standard statistical software, evaluate the fit of themodel, and interpret the results. explain the concept of confounding in epidemiological studies anddemonstrate how to control/adjust for confounding using statistical models. apply and interpretappropriate statistical models for studying effect modification. critically evaluate the methodologicalaspects (design and analysis) of a scientific article reporting an epidemiological study. Learning outcomesare classified according to Bloom´s taxonomy: knowledge, comprehension, application, analysis, synthesis,and evaluation.Kursens innehåll : This course focuses on the application of linear and logistic regression in the analysis ofepidemiological studies. Topics covered include a brief introduction to continuous and binary outcome data,univariable and multivariable models, interpretation of parameters for continuous and categoricalpredictors, flexible modeling of quantitative predictors, confounding and interaction, model fitting andmodel diagnostics. Arbetsformer : Lectures, computer lab with exercises focusing on analysis of real data sets usingstatistical software, exercises not requiring statistical software, group discussions, literature review.Examination : To pass the course, the student has to show that the learning outcomes have beenachieved. The course grade is based solely on a written examination. The focus of the exam will be onunderstanding concepts and their application to analysis of epidemiological studies rather thanmathematical detail. The course examination will be held within one week of the final day of the course.Students who do not obtain a passing grade in the first examination will be offered a second examinationwithin two months of the final day of the course. Students who do not obtain a passing grade at the firsttwo examinations will be given top priority for admission the next time the course is offered. If the course isnot offered during the following two academic terms then a third examination will be scheduled within 12months of the final day of the course.Obligatoriska moment : Examination.Antal studenter : 12 25Urval av studenter : Prerequisite knowledge equivalent to Epidemiology I and Biostatistics I orcorresponding courses. Eligible doctoral students will be prioritized according to 1) the relevance of thecourse for their research, and 2) the stated motivation for attending the course. To be considered, pleasesubmit a completed application form and give all information requested including a short description ofcurrent research and motivation for attending, as well as an account of previous courses taken.Övrig information : The course is extended over time in order to promote reflection and reinforcelearning. The course will be given the following dates: December 7, 9, 11, 14, 16. Compared to theprevious version of this course, linear regression will be covered more and thus the number of highereducation credits is increased to 2.0 from 1.5.
Kursansvarig : Nicola OrsiniInstitutet för miljömedicin
Kontaktpersoner : Ida Kettley CronfalkInstitutet för miljömedicin
Title : Människans Fysiologi en översikt
Kursnummer : 2827Antal högskolepoäng : 3.0Datum : 20151216 20160115Språk : SvenskaNivå : ForskarnivåKursansvarig institution : Department of Physiology and PharmacologySärskild behörighet : Kursens lärandemål : Studenten ska efter genomgången kurs ha översiktlig kunskap och förståelse förhur människokroppens organsystem fungerar och samverkar under normala betingelser. Kursinnehållet skakunna användas för fortsatt fördjupning inom en forskarutbildning där vissa humanbiologiska kunskaper ärav värde. Färdigheter Skriftligt kunna redogöra för organsystemens funktion. Sammanställa och delgeinformation skriftligt för utvalda fördjupningsområden. Förhållningssätt och värderingsförmåga Uppvisaett kritiskt och vetenskapligt förhållningssätt till data som presenteras under föreläsningar och ikurslitteratur. Kursens innehåll : Nervsystemets fysiologi Muskel Autonoma nervsystemet och endokrinologi Högre hjärnfunktioner Hjärta och cirkulation Njure och syrabas Respiration Digestion Samtsamspelet mellan olika organsystem.Arbetsformer : Kursen innehåller föreläsningar, gruppdiskussioner i form av frågestunder samtproblembaserad undervisning. Dessutom ges en frivillig dugga som ger bonuspoäng på tentamen.Examination : För att bli godkänd i kursen måste studenten visa att lärandemålen har uppnåtts. Dettabedöms genom en skriftlig tentamen. Obligatoriska moment : Moment som är obligatoriskt under kursen är tentamen. I anslutning till kursenges ett resttentamenstillfälle.Antal studenter : 10 20Urval av studenter : Urval av kursdeltagare baseras på 1) datum för doktorandregistrering (där tidigareregistreringsdatum har förtur) 2) kursplanens relevans för sökandes doktorandprojekt (enligt motivering). Övrig information : Bland föreläsarna kommer ni att träffa Håkan Westerblad och Bo Rydqvist.Föreläsningarna ligger för det mesta på förmiddagarna.
Kursansvarig : Hakan WesterbladInstitutionen för Fysiologi och Farmakologi
Kontaktpersoner : Charlotte SchönbeckInstitutionen för Fysiologi och Farmakologi
Title : Introduction to Quantile Regression and Related Methods
Kursnummer : 2833Antal högskolepoäng : 1.5Datum : 20151102 20151106Språk : EngelskaNivå : Doctoral levelKursansvarig institution : The institute of Environmental MedicineSärskild behörighet : Biostatistics I or corresponding knowledge.Kursens lärandemål : The main objective of this course is to introduce regression techniques foranalyzing data arising in epidemiology, environmental health, and other global health domains. After a briefreview of regression methods, the course will focus on quantile estimation. Statistical reasoning will beemphasized through problem solving and applications. At the completion of this course, a student will beable to: 1) Interpret commonly used statistics and regression methods; 2) When reading journal articles,identify potential errors and limitations in the analyses; 3) Develop judgment about which statisticaltechnique to use in a given situation; and 4) Implement the described statistical techniques, includingestimation and hypothesis testing, using statistical software.Kursens innehåll : Course Topics: The following is a tentative list of topics to be covered: 1. Descriptivestatistics ¿ measures of location and dispersion; empirical quantiles 2. Advantages of using quantiles.Examples from the existing literature 3. The concept of regression. Examples of regression 4. Extending theconcept of quantiles to a regression framework 5. Quantile regression: examples and applications to realdatasets 6. Censored quantile regression: examples and applications to real datasets Arbetsformer : Laboratory Sessions: Lab sessions will take place every afternoon; they will be used toreview the material that was covered in the lectures and to work through additional problems andcomputing issues. During these handson lab sessions, the students will have the opportunity to utilize themethods presented in the morning lectures to the analysis of reallife data examples. Computing: Thiscourse will provide an introduction to the R statistical package. R is free software and can be downloaded atwww.rproject.org. Full information about the usage of the software will be provided during the course. Anystudent who has his or her own favorite statistical package is welcome to use it. The final exam does notrequire the use of a computer.Examination : Final assignment that assesses that all learning outcomes of the course are reached.Obligatoriska moment : Antal studenter : 15 30Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information :
Kursansvarig : Matteo BottaiInstitutet för miljömedicin08524 870 [email protected]
Kontaktpersoner : Johanna BergmanInstitutet för miljömedicin
Nobels väg 13
17177Stockholm
Title : Philosophy of science and research ethics, statistics andoral scientific communication
Kursnummer : 2839Antal högskolepoäng : 7.5Datum : 20150921 20151023Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Learning, Informatics, Management and EthicsSärskild behörighet : Kursens lärandemål : communicate own research well adjusted to different contexts by using variousmeans of communication based on theories of communication and learning assess the quality of peers'communication of own research and give constructive feedback accordingly articulate considerations onphilosophy of science and research ethics in relation to the own research project be able to performbasic summaries, analyses and presentation of data, as well as have enhanced their ability to recognize,understand and critically view the statistics being presented in medical articles Kursens innehåll : Philosophy of science and research ethics 1.5 hp Oral communication techniques 3 hp Basic statistics 3 hp Arbetsformer : The pedagogic framing is based on student activity with interactive lectures, seminars andworkshops. The scheduled facetoface activities in the course will be mixed with individual work andfeedback from teachers and peers via the web based platform PingPong.Examination : The knowledge, skills and attitudes acquired in the course will be assessed through writtenassignments and oral presentations.Obligatoriska moment : Assignments, seminar and group activities. Absence from seminar and groupactivities can be compensated by self studies and written assignments.Antal studenter : 24 30Urval av studenter : The selection for this general science course will be based on your admission date todoctoral education (priority given to earlier registration date). Please make sure that you have entered thecorrect registration date for doctoral education in your personal profile. Övrig information : The content and focus of course 2839 is equivalent to the three independent courses2144 "To communicate science in different contexts", 1386 "Ethics and Philosophy of Science" and1383/2609 "Basic Course in Medical Statistics". It is required that students have not attended any of thesecourses previously (or their equivalent). Transfer of credits from previously attended courses will not beapproved/possible. This is a five week course which requires time for independent work outside ofscheduled class time. Scheduled class room sessions are on the following dates: 2125 September, 28September2 October, 59 October, 1216 October and 1923 October. The course is given in ENGLISH.
Kursansvarig : Cormac McgrathInstitutionen för lärande, informatik, management och etik
Kontaktpersoner :
Title : The third dimension of nuclear functions
Kursnummer : 2841Antal högskolepoäng : 1.5Datum : 20151012 20151016Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Microbiology, Tumor and Cell BiologiSärskild behörighet : ingen särskild behörighet efterfrågasKursens lärandemål : Following the completion of the course the students will be able to describe thebasic principles of 3D genome organisation and how this relates to nuclear functions such as transcription,replication, DNA repair and telomere maintenance. The students will also be able to design experiments forstudying the 3D structure of chromatin, compartmentalisation of nuclear functions in the nuclear space andto critically evaluate results obtained with these techniques.Kursens innehåll : The course covers the basic principles of genome regulation in 3D and how marks ofthe primary chromatin fibre relate to the 3D structure of chromatin. Particular attention will be paid to theregulation the nuclear architecture during development, and its role in lineage specification by means ofcoordination of transcription and replication in space and time. Speakers will include the course organizersand several wellknown international researchers dedicated to research on relevant aspects of chromatin.Arbetsformer : The learning activities used in the course include lectures, research seminars and researcharticle presentation by the students. Each student will present a recent publication in the form of a journalclub. Students will also be encouraged to actively participate in the course. There will be substantial timefor discussions after the lectures and research seminars.Examination : Examination is based on the journal club presentation and a written test. Every student willpresent a preselected article, and will be the opponent for the presentation of a fellow student. Thestudent's performance at these two occasions combined with the test results will be the basis for the finalassessment.Obligatoriska moment : The lectures, seminars and journal club presentations are compulsory.Compensation according to the instructions of the course director.Antal studenter : 8 20Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : This is a 5day (Monday to Friday) fulltime doctoral course offered by the'Tumorbiology/Oncology doctoral programme'. The course will take place at the Department ofMicrobiology, Tumor and Cell Biology.
Kursansvarig : Anita GöndörInstitutionen för mikrobiologi, tumör och cellbiologi08 524 862 [email protected]
Kontaktpersoner : Anita GöndörInstitutionen för mikrobiologi, tumör och cellbiologi08 524 862 [email protected]
Title : The cell cycle
Kursnummer : 2843Antal högskolepoäng : 1.5Datum : 20151116 20151120Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Biosciences and NutritionSärskild behörighet : Kursens lärandemål : Upon completion of the course the students should: Be able to explain the keyaspects of the cell cycle Show uptodate knowledge on the molecular mechanisms that regulate the cellcycle. Explain the relevance of the cell cycle for health and disease. Understand and discuss diversepharmacological strategies targeting the cell cycle. Critically evaluate different experimental models andtechnologies used in cell cycle research Be familiar with stateofthe art methodologies used for studies incell cycle Be capable of designing experiments for studies on cell cycle Be able to relate the contents ofthe course to their specific projects and field of research Present and discuss the most recent findings incell cycle research Kursens innehåll : The course will cover key aspects of cell cycle, including cell cycle control, DNAreplication, chromosome segregation, checkpoints, mitosis and asymmetric cell division. During the course,we will openly and critically discuss the latest research advances in a broad spectrum of experimentalorganisms. The course will have a special focus on the molecular events that regulate the cell cycle andtheir relevance for human diseases, such as developmental disorders and cancer.Arbetsformer : The teaching modes will consist of lectures and research seminars by invited speakers,including time for discussions with each speaker. In addition, the students will work in groups, with aguiding tutor, to critically review original articles that are relevant to the content of the course, with specificfocus on the background, the technologies and experimental models used and the significance andimplication of the findings. Finally, the students will work on teams to prepare posters that summarise themost important 'takehome messages' of the course and putting them in the context of their own researchactivities. The original papers and the posters will be presented in a minisymposium that will take place thelast day of the course. Examination : Each student will be examined by his/her individual journal club presentation and his/hercontribution to the poster session that will take place during the minisymposium. All learning outcomes willbe assessed.Obligatoriska moment : Attendance to the lectures, research seminars, journal clubs and minisymposium are compulsory. Compensation could be done according to the instructions of the coursedirector. Antal studenter : 15 20Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : 'The cell cycle' is a 5day (Monday to Friday) fulltime doctoral course offered by the'Developmental biology and cellular signalling doctoral programme'. The course will take place at theBioscience and Nutrition department (South Campus, Huddinge).
Kursansvarig : Victoria Menendez BenitoInstitutionen för biovetenskaper och näringslära
Kontaktpersoner :
Title : Exploring entrepreneurial opportunities in research
Kursnummer : 2844Antal högskolepoäng : 1.5Datum : 20151116 20151120Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Learning, Informatics, Management and EthicsSärskild behörighet : Kursens lärandemål : After the course, a doctoral student shall be able to; demonstrate anunderstanding of the opportunities of innovation, entrepreneurship and utilization, use basic business toolsin their own research project, assess their new skills and reflect on the possible future effects (individual,organization or society).Kursens innehåll : The course aims to increase the awareness of the potential of innovation andentrepreneurship. It begins with an introduction to entrepreneurship, what it is and how it can be used inthe doctoral education. The doctoral students are then given a number of practical business tools to use in aminor innovation projects based on their own research.Arbetsformer : The course runs over five full days, including two days of training and three days of ownwork. Learning activities consist of seminars and workshops as well as group and individual work. With theindividual assignments the doctoral students are given the opportunity to take a closer look at the actualbenefits of the new knowledge and put it into a larger context, with value for their own research.Examination : The doctoral students are examined by a written individual assignment and design of aposter. In the written assignment the doctoral student describes what they learned, how it can be utilised intheir own research and reflect on the effects for the future. The poster describes a concrete example ofapplication of the new knowledge in their own research project.Obligatoriska moment : Attendance is mandatory. The course director assesses if and in that case howabsence can be compensated.Antal studenter : 10 20Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : The course will be given at KI Campus in Solna, in collaboration with the actors of thelocal innovation system.
Kursansvarig : Hanna JanssonInstitutionen för lärande, informatik, management och [email protected]
Kontaktpersoner :
Title : Cellbased heart regeneration
Kursnummer : 2845Antal högskolepoäng : 1.5Datum : 20150928 20151002Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Cell and Molecular BiologySärskild behörighet : Kursens lärandemål : Upon completion of the course, the doctoral students will be able to describeimportant principles in studying the development of the human heart, relate these to heart disease, andcritically evaluate important methods and technologies applied in the context of regenerative medicine forheart disease. Kursens innehåll : The developmental principles, logic, pathways, technology, and model systems tounravel human heart disease. Regenerative cardiology, bioartificial heart tissues and translational bench tobedside regenerative medicine. Arbetsformer : The learning modes used in the course include lectures, discussions, seminars and a oneday research symposium. Examination : The students are examined with individual and group presentations on the course themes. Obligatoriska moment : Participation in the group discussions and student presentations is mandatory.Compensation is according to the instructions of the course director.Antal studenter : 20 35Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : The course is jointly organized by SCRMC/Emerging Strategic Research Theme onStem Cell at Hong Kong University and DBRM Research School (www.dbrm.se) at KI. The course takesplace at CMB, seminar room A216, Berzelius v 35 in Solna. One day of the course is organized in the formof a research symposium at Nobel Forum.
Kursansvarig : Matti NikkolaInstitutionen för cell och molekylärbiologi
Kontaktpersoner :
Title : Integration of Neuroimaging and Cognition in NormalAging and Dementia
Kursnummer : 2846Antal högskolepoäng : 1.5Datum : 20151109 20151113Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Neurobiology, Care Sciences and SocietySärskild behörighet : Previous knowledge in cognitive processes, brain anatomy and neuroimaging is arequirement.Kursens lärandemål : After attending the course, the graduate student will be able to (1) describe anddifferentiate neural and cognitive profiles that accompany normal aging and different types of dementia (2)select the most appropriate methods in order to address scientific questions pertaining to neural correlatesof cognitive functions, (3) identify, combine and test different risk factors for dementia (genetic, biological,environmental) on brain integrity and cognition, (4) compute analyses in the most commonly usedneuroimaging softwares (e.g., SPM, Freesurfer). Kursens innehåll : This course focuses on the study of the neural bases of cognitive decline in normalaging and dementia. The main neuroimaging methods included in this course are: Structural MRI (includingvolumetry and DTI), functional MRI, molecular PET and MRI (neurotransmission (e.g., dopamine) andmarkers of Alzheimer's disease amyloidbeta, iron). Each day of the course constitutes a specific subtopic.Day 1 is about "the essentials" on dementia, cognitive trajectories and neural changes in normal aging anddementia. On Days 2 and 3, cognitive and neuroimaging data will be integrated (day 2: structural andfunctional MRI; day 3: molecular neuroimaging PET/MRI, and multimodal and multivariate imaging). OnDay 4, genetic, biological and environmental modifiers of cognition and neural integrity are considered. OnDay 5, an introduction to cognitive and brain plasticity in aging is provided. Arbetsformer : The course contains: (1) short lectures that provide uptodate knowledge about the braincorrelates of cognitive decline in normal aging and dementia, (2) seminars where methods linkingneuroimaging and cognitive data are discussed based on the literature, (3) handson sessions where thestudents compute analyses on real data. Each subtopic (e.g., atrophy and cognition in normal aging anddementia) includes one lecture with relevant literature, a seminar on the methods used to address thequestion of interest and/or handson implementing the methods on real data. Examination : The students will be evaluated on group presentations during seminars and on an individualwritten examination consisting of a 2page essay describing how the student can test his/her hypothesesrelated to his/her thesis based on the knowledge and methods acquired during the course. After the end ofthe course, one week is given to allow the students to send the essay.Obligatoriska moment : All parts of the course are compulsory. Absence is compensated for by a writtenassignment.Antal studenter : 8 20Urval av studenter : We welcome students from different academic backgrounds (master in psychology,neuroscience, medicine, biology, engineering, neuroepidemiology). Students with specific backgrounds suchas cognitive psychology and neuroscience will be prioritized. Selection will be based on 1) the relevance ofthe course syllabus for the applicant's doctoral project (according to written motivation), 2) date forregistration as a doctoral student (priority given to earlier registration date).Övrig information : The course is held during 5 consecutive days (MondayFriday) from ca 9.00 to 16.00(with breaks). Address: Aging Research Center (ARC), Gävlegatan 16, 113 30 Stockholm.
Kursansvarig : Grégoria KalpouzosInstitutionen för neurobiologi, vårdvetenskap och samhälle
Kontaktpersoner : Alireza SalamiInstitutionen för neurobiologi, vårdvetenskap och samhälle
Francesca MangialascheInstitutionen för neurobiologi, vårdvetenskap och samhälle
Title : Cancer and cancer stem cells
Kursnummer : 2849Antal högskolepoäng : 1.5Datum : 20151116 20151120Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Medicine, SolnaSärskild behörighet : Kursens lärandemål : After completion of the course, the student will be able to describe the concept ofcancer stem cells, the relationship between cancer and cancer stem cells, as well as assays to identify thesestem cells. Within this framework, the student will be able to demonstrate an understanding for thedevelopment of cancer in the context of solid tumors and leukemia. In addition, the students will be able tocritically evaluate the advantages and drawbacks of basic mechanisms employed for cancer treatment inthe clinic. Kursens innehåll : The course covers key principles of cancer development and cancer therapies, andprovides an appreciation for the concept of cancer stem cells and its implications from a clinical and basicscience perspective. This includes a general overview of molecular and cellular mechanisms underlyingcancer development, drug resistance, disease relapse, cancer stem cells, therapeutic stem celltransplantation and clinical care for the treatment of solid tumors and leukemia, immunological cancerrelated considerations, and perspectives for novel cancer therapies. The student will be required to take anactive part in this course by contributing with presentations and discussions related to cancer and cancerstem cells.Arbetsformer : The pedagogic frame of this course is based on lectures combined with topicrelatedresearch articles. The course includes workshops where the students are required to present articles,integrate the knowledge acquired from lectures and reading of the articles, and actively discuss theiracquired knowledge as a group. Each student will research, prepare and present his or her examination taskorally.Examination : The individual performance of each student will be evaluated separately based on theirpresentation of a cancer stem cellrelated topic and the feedback the students provide to their fellowstudents. The content and organization of the presentation and discussion will follow a format provided bythe instructors.Obligatoriska moment : The lectures and discussions are mandatory. Absence is compensated accordingto the instructions of the course director.Antal studenter : 10 30Urval av studenter : The selection process will be based on a comprehensive assessment of theapplicants, including students and postdoctoral researchers: 1. Motivation for the course 2. Topic of theirPhD project 3. Years since PhD registration (priority will be given to earlier registration date) Övrig information : The course is organised by the Department of Medicine, KI Solna and the Center forHematology and Regenerative Medicine, KI Huddinge. The course sessions will take place at KI Solna and KIHuddinge campuses. There will be a course lunch during the course week.
Kursansvarig : Natalia LandazuriInstitutionen för medicin, Solna
Kontaktpersoner : Hong QianInstitutionen för medicin, Huddinge
Natalia LandazuriInstitutionen för medicin, Solna
Title : Initiating entrepreneurial thinking in connection toresearch
Kursnummer : 2852Antal högskolepoäng : 1.5Datum : 20150914 20151218Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Learning, Informatics, Management and EthicsSärskild behörighet : Kursens lärandemål : After the course, a doctoral student shall be able to; describe selected businesstools for e.g. needs assessment, ideation, market analysis and business modelling, understand thequalities and challenges with interdisciplinary team work, assess their new skills and reflect on theimplementation in research and development.Kursens innehåll : Entrepreneurship courses give their participants tools to come up with ideas, plan andcarry out projects. These courses also increase the participants knowledge of what happens outside theirown academic context. This course contains a selection of lectures from courses within everything fromideation and design to startup and business modelling. Each course is unique in that the participatingdoctoral student selects six (6) lectures from a sample of the courses offered within the framework of theStockholm School of Entrepreneurship (SSES).Arbetsformer : The course is offered in evenings and parttime over one semester. The doctoral studentselects, in discussion with the course director, at the beginning of the course six (6) lectures to attend.Learning activities consist of these lectures (and/or seminars), an online individual learning log and anindividual reflection. With the individual assignments the doctoral student is given the opportunity to take acloser look at the actual benefits of the new knowledge and put it into a larger context, and value for theirown research.Examination : The doctoral students are examined by an individual learning log and an individualassignment. In the assignment the doctoral student describes what they learned, how it can be utilised intheir own research and reflect on the effects of the new knowledge.Obligatoriska moment : Attendance at six (6) selected lectures is mandatory. The course directorassesses if and in that case how absence from compulsory parts can be compensated.Antal studenter : 10 20Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : The course is given by KI but individual lectures/seminars will be held at the RoyalInstitute of Technology (KTH), Stockholm School of Economics (SSE), Stockholm University (SU) and/or theUniversity College of Arts, Crafts and Design (Konstfack). Find out more about the different topics/coursesthat will form the basis for this course at www.sses.se. The course can be completed in a shorter timeperiod depending on individual interest.
Kursansvarig : Hanna JanssonInstitutionen för lärande, informatik, management och [email protected]
Kontaktpersoner :
Title : Translational lung cancer research
Kursnummer : 2854Antal högskolepoäng : 1.5Datum : 20151021 20151022Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Microbiology, Tumor and Cell BiologiSärskild behörighet : Kursens lärandemål : At the end of the course the student is expected to: Understand lung cancertissue processing for biobanking, and extraction of DNA, RNA and proteins Know how to apply moleculartechniques on clinical lung cancer tissue samples Have basic knowledge about lung cancer pathology Beoriented about the frontlines of genomic, transcriptomic and proteomic lung cancer research Understandstandard and targeted therapy concepts for lung cancer, and coupled biomarker research and diagnostics. Kursens innehåll : The course aims to convey a basic understanding of how modern high throughputmolecular analyses can be applied to clinical lung cancer tissue, with regard to opportunities and limitationsimposed by diagnostic sampling and tissue processing. The students will be introduced to basic diagnosticalgorithms, treatment strategies, cancer histopathology and molecular diagnostics, as well as to exploratorytranslational research in lung cancer genomics, transcriptomics and proteomics. A final goal is that thestudents shall be able to formulate a translational project related to their own research interest.Arbetsformer : The course will be organized as a one day lecture/seminar module (in Stockholm), followedby a second day with microscopy seminars and visits/introductions to pathology laboratory units for tissueprocessing, biobanking and molecular diagnostics (in Uppsala). As a basic learning process we emphasizeinformal critical dialectic constructive discussions throughout the course ("Filip och Fredrik pedagogic"). Thestudents will be provided before the starting of the course with material that they should read in advanceand that will be used as base for the lectures and discussions during the course days.Examination : To pass the course the students must show that they have reached the learning outcomesof the course. This will be assessed formatively during the two days "on site" and by writing a potentialtranslational lung cancer project related to their own research interests afterwards.Obligatoriska moment : Full attendance during the two days "on site" module is compulsory.Antal studenter : 10 15Urval av studenter : Selection of students will be based on personal motivation and the relevance of thecourse content for their research. Priority will be given to register doctoral students at KI and UppsalaUniversity. If necessary, a further selection will be based on the date for registration as a doctoral student.Övrig information : The course is organised in two days. The first day, organised as lecture/seminarmodule, will take place at the Dept of Cell and Molecular Biology (CMB) Karolinska Institutet, Stockholm.The second day, with microscopy seminars and visits/introductions to pathology laboratory units for tissueprocessing, biobanking and molecular diagnostic, will be held at the Department of Pathology, Rudbecklaboratory, Uppsala University Hospital. Course directors Johan Botling [email protected] PatrickMicke [email protected] Course coordinator: Teresa Frisan [email protected]
Kursansvarig : Teresa FrisanInstitutionen för cell och molekylärbiologi08[email protected]
Berzelius väg 35
S17177Stockholm
Kontaktpersoner :
Title : Digital photomicrography
Kursnummer : 2855Antal högskolepoäng : 1.5Datum : 20151019 20151023Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Laboratory MedicineSärskild behörighet : Kursens lärandemål : After completing the course, the participants will have a working knowledge of thefundamentals of optical microscopy and be able to use appropriate presentation methods for conveyingtheir research results in a clear and informative way. Multimedia software and image processing softwarewill be used including Adobe Photoshop® as well other digital microscopy software for image acquisition.Kursens innehåll : The course will include theory and practice investigating conventionallight microscopy,dark field, ultraviolet fluorescence, phase contrast and interference (DIC). Additionally, the course willdedicate one day to confocal microscopy and the Analysis and Measurement of Data through theoretical andpractical sessions. Following the mastery of microscopy, the course explores fundamentals of digitalphotography. The participants will be exposed to digital cameras and their proper operation. There is anoverview of video and still digital cameras relative to application needs. Relevant issues such as capture,processing, transmission and storage concerns are explored. Participants will work individually with popularimage editing softwares such as Adobe Photoshop® as well as other imaging softwares. Exercises havebeen created to develop image processing imperatives such as file resolution and type, adjusting of tonesand contrast, and composition. Arbetsformer : The course will consist of lectures and practical micrography laborations.Examination : Each student's knowledge will be assesed through an oral examination during a practicalmicroscopy laboration.Obligatoriska moment : Practical micrography sessions are compulsory, as is an overall attendance of100%. Absence can be compensated for by completing extra work as agreed with the course organizer.Antal studenter : 10 18Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : This course has a strong theoretical and handson component evenly distributed overthe five days and will run from 8:3017:00 Monday Friday in lecture room Bi515, floor 5, KTH/Teknik ochHälsa, (Bipontus) Alfred Nobels Allé 10 at KTH Huddinge University Campus. The workshop explores in gooddepth fundamentals of bright field microscopy, as well as various other microscopy techniques such asfluorescence and phase. A significant amount of content is also dedicated to electronic imaging and imageprocessing using Adobe Photoshop®. This is an approved PhD course, number HL201U at KTH RoyalInstitute of Technology, and 2855 at Karolinska Institutet, and has a credit value of 1.5 point. The course isrun in conjunction with contract education for external participants. The number of participants is limited to18.
Kursansvarig : Moustapha HassanInstitutionen för laboratoriemedicin08585 838 [email protected]
Kontaktpersoner : Jennifer UsterudInstitutionen för laboratoriemedicin08585 832 [email protected]
Title : Teaching and Learning in Higher Education: educationalcourse for doctoral students a distance course
Kursnummer : 2856Antal högskolepoäng : 4.5Datum : 20150911 20151217Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Learning, Informatics, Management and EthicsSärskild behörighet : Kursens lärandemål : At the end of the course, students are expected to: Be familiar with differentroles of a professional university teacher and current conditions related to teachinglearning within highereducation. Be able to use educational concepts in discussions of teaching and learning situated in HigherEducation. Design teaching in regards to outcome or competency based frameworks for curriculumdesign and also in relation to theories of learning or research on student learning in higher education. Kursens innehåll : Roles and conditions related to being a professional university teacher. Studentslearning in higher education Different forms of teaching and learning activities Design of teaching forlearning Arbetsformer : The course is based on theories of experiential learning, a reflective attitude and learningthrough participation and collaboration. Teaching is conducted via the learning platform Ping Pong and isconstructed largely around the students' own reading of literature, written assignments, peer feedback andonline group discussions. The majority of assignments are based on the students describing, examiningand reflecting over their own teaching and relating this to literature/theory.Examination : In a final examination assignment, the participant apply course content in reviewing anddiscussing development of one a teaching situation related to their own practice. This is presented througha written essay. To pass the course, the participant is required to: Complete all module assignments andparticipate actively in group work and discussions online during the course Conduct the assignment ofbeing a "critical friend"; observing and giving feedback on a colleagues teaching. Giving feedback to apeers´ examination assignment Pass the final examination assignment, which is judged using assessmentcriteria. Obligatoriska moment : Participation in group discussions online Doing the examination assignment Provide peer feedback on course and examination assignments. Antal studenter : 5 7Urval av studenter : Priority will be given to students with planned teaching included in their individualstudy plan. Enter a brief motivation and indicate the area within which the teaching is to be given.Secondly, selection will be based on registration date as a doctoral student. Please make sure that you haveentered the correct registration date for doctoral education in your personal profile.Övrig information : The course aims to prepare students for teaching in higher education and contributeto the professional development as teacher. The course is a distance course and teaching is conducted viathe learning platform Ping Pong and is constructed largely around the students' own reading of literature,written assignments, peer feedback and online group discussions. The course is given in English.
Kursansvarig : Cormac McgrathInstitutionen för lärande, informatik, management och etik
Kontaktpersoner : Ingrid SmedbergInstitutionen för lärande, informatik, management och etik08524 837 [email protected]
Title : Orientation in qualitative research methods
Kursnummer : 2857Antal högskolepoäng : 1.5Datum : 20151105 20151119Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Public Health SciencesSärskild behörighet : NoneKursens lärandemål : At the end of the course the students should be able to: understand and explainthe theoretical basis for the main qualitative methods understand and explain the main differencesbetween qualitative and quantitave research know the main qualitative research methods (contentanalysis, phenomenography, grounded theory, narrative analysis, discourse analysis), understand thedifferences between them and know how to choose the method most adequate for the research question athand plan and carry out a qualitative research interview, a focus group discussion and an observationsession, including know how to handle the information gathered and analyse the data understand theethical aspects of qualitative research and how to handle them in a professional way explain how thevalidity/quality is assessed in qualitative research prepare the outline of an article based on data collectedduring the course Kursens innehåll : Theoretical basis for qualitative research The main qualitative research methods(participant selection, data collection, handling of data, analysis) Validity/quality assessment of qualitativeresearch Ethics in qualitative research Reading and writing qualitative research Arbetsformer : Lectures Group work Practising observations, interviewing and moderating focusgroup discussions Practising handling of qualitative data by hand and using software Practising how toanalyse qualitative data and writing it up Seminars to discuss the experiences from the practical sessions Examination : an individual written examination to assess aquired knowledge and understanding ofqualitative research assessment of the practical assignments and how the experiences are presented inthe seminars the drafts for an article based on the data collected in the practical assignments to assessthe understanding of the process and ablity to analyse data and condense information Obligatoriska moment : Practical assignments are compulsory and have to be carried out during thecourse. This cannot be compensated for.Antal studenter : 8 20Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information : The course meets inperson on three consecutive Thursdays, 5 November, 12November and 19 November; with practical assignments outside of course
Kursansvarig : Rachel IrwinInstitutionen för folkhälsovetenskap
Kontaktpersoner :
Title : Longitudinal data analysis classical and modernstatistical methods
Kursnummer : 2858Antal högskolepoäng : 3.0Datum : 20151102 20151113Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Learning, Informatics, Management and EthicsSärskild behörighet : Basic medical statisticsKursens lärandemål : After successful completion of the course the student will be able to: 1. Understandthe underlying characteristics of longitudinal data 2. Identify appropriate tests for longitudinal studies 3.Manage longitudinal datasets and prepare these for statistical analysis using statistical software programSPSS 4. Apply both simple and complex statistical methods of longitudinal data 5. Use SPSS to perform theabove mentioned statistical analysis 6. Present and interpret the results of analysis Kursens innehåll : The aim of the course is to introduce statistical models and methods for the analysis oflongitudinal data and to develop statistical skills of analyzing correlated data. The main focus will be onfrequently used statistical methods and how these should be used to provide more insight concerningresearch questions in longitudinal studies. Thus the course covers both classical and modern methods toanalyze longitudinal data. Topics include Univariate repeated measures analysis of variance, Multivariaterepeated measures analysis of variance, Drawbacks and limitations of classical methods; General linearmodels for longitudinal data; Linear mixed effects models; Non linear longitudinal data models and handlingmissing data. The underlying mathematical theory will not be stressed, and the main focus will be onconcepts and applications.Arbetsformer : Teaching methods include lectures, computer based exercise and seminars 34 scheduleddays during two weeks. Participants will have access to materials from a number of studies and are giventhe opportunity to use the statistical software program, SPSS during practice sessions. In addition, you willhave seminars, group discussion and presentations. Examination : Assessment of the intended learning outcomes by the computer based exercises (should allbe approved) and the final seminar. Obligatoriska moment : Computer based exercises, seminars, presentations and some lectures aremandatory. The course leader assesses whether and if so, how absence can be compensated.Antal studenter : 18 20Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date) Övrig information : The course will consist of four scheduled whole days per week for two weeks. Coursedates: 2 3/11, 5 6/11, 9 10/11, 12 13/11; 2015
Kursansvarig : Mesfin TessmaInstitutionen för lärande, informatik, management och etik
Kontaktpersoner : Margareta KrookBrandtInstitutionen för lärande, informatik, management och etik52487118Margareta.Krook[email protected]
Title : DNA damage and maintenance of genome integrity
Kursnummer : 2859Antal högskolepoäng : 1.5Datum : 20151012 20151016Språk : EngelskaNivå : Doctoral levelKursansvarig institution : The institute of Environmental MedicineSärskild behörighet : Kursens lärandemål : After the course, the student shall be able to: Regarding knowledge andunderstanding, describe how exposure to various environmental agents and anticancer drugs can lead tomodifications of DNA account for various types of DNA damage and how they can be analyzed, as well asthe molecular mechanisms by which cells detect, signal, and repair DNA damage to maintain the integrity ofthe genome describe epigenetic mechanisms in relation to genome instability account for theconnections between DNA damage/DNA repair capacity and human disease, particularly cancer Regardingskills and ability, plan and perform one established method used for studying genotoxic effects such ascomet assay, micronuclei assay or gammaH2AXstaining Regarding judgment and approach, evaluatetheir own results and critically assess research papers relevant to the field of DNA damage, DNA repair andgenome instability. Kursens innehåll : Drugs and many environmental pollutants such as airborne particles, hydrocarbons,metals, manufactured nanoparticles as well as different mixtures may affect the genome integrity bycausing changes in the genome or epigenome. Effective maintenance and interpretation of the genome isessential for normal cell division, tissue homeostasis, and cellular and organismal fitness. DNA damage anderrors in DNA replication, recombination and repair, and epigenetic mechanisms all contribute to genomicinstability and tumor progression. The course focuses on the formation of DNA damage as well as molecularmechanisms devoted to the preservation of genome integrity in eukaryotic cells. Topics include DNAdamage formation and analysis, DNA damage recognition and repair pathways, cell cycle checkpointmechanisms, and DNA repair as target for therapeutic intervention. The course emphasizes the relevance ofthese mechanisms in human disease development. The course also includes a practical part in which thestudents perform one selected assay for assessing DNA damage following cellular exposure to a substanceof interest for the student. The course builds on a strong core of researchers with expertise in multipleaspects of genome biology across a broad range of research areas including Toxicology, Cancer biology, andMolecular Biology research.Arbetsformer : The teaching includes lectures, seminars, laboratory sessions, oral presentations and groupassignments.Examination : The students will present in an oral form their laboratory group work and demonstrate theirskills in discussing their own work and the work presented by their fellow students. Obligatoriska moment : Participation in the laboratory sessions is mandatory. Absence can becompensated with an individual task.Antal studenter : 10 20Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date)Övrig information :
Kursansvarig : Kristian DreijInstitutet för miljömedicin08524 875 [email protected]
Kontaktpersoner : Johanna BergmanInstitutet för miljömedicin
Nobels väg 13
17177Stockholm
Title : Extracellular vesicles: a tool for diagnostics and therapy.
Kursnummer : 2860Antal högskolepoäng : 2.0Datum : 20151109 20151113Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Laboratory MedicineSärskild behörighet : Kursens lärandemål : After the completed course, the student will be able to describe the basics ofextracellular vesicles (EV) biology and function as well as a number of novel technologies and approaches inEV isolation and characterization. The student can demonstrate an interdisciplinary understanding of centralconcepts in EV biology and critically evaluate different methods and techniques used. The student will beable to extract and integrate information from stateoftheart lectures in combination with overviewarticles and literature searches on the internet within the research field. Kursens innehåll : The course covers key concepts in EV biology and function from the laboratory to thepatient in the clinic. This includes a general overview of EV isolation and characterization approaches, toolsas diagnostics and prognostics of various diseases and the possible use of EVs in therapy. Experts will givean advanced summary of the latest events in the EVfield. The student will be required to take an activepart, contribute and value discussions in workshops on relevant topics in the EVfield. Networking withstudents and speakers is highly encouraged in this course. Arbetsformer : The pedagogic framing of this course is based on lectures with corresponding reviewpapers. The course includes workshops with illustrative predicaments where the students are required totake an active part in the discussions. Group discussions and workshops will be conducted where thestudents discuss and integrate information from the lectures and review papers. The students prepare andpresent their examination task in a written report that is handed in after the course.Examination : An individual written project report consisting of 2 A4 pages covering one of three topicsprovided by the course leaders is expected to be handed in after the course. The last date to hand in thereport is 1 week after the last day of lectures on the course. The written report will be evaluated on theunderstanding of central concepts in EV biology and integration of discussions from the course and providedcourse literature.Obligatoriska moment : The lectures, workshops and discussions are mandatory. Compensationaccording to the instructions of the course director.Antal studenter : 10 20Urval av studenter : Selection will be based on 1) the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation), 2) date for registration as a doctoral student (prioritygiven to earlier registration date). Post docs and master students are welcome to apply and will beaccommodated if spaces are available. Övrig information : The course covers key concepts in EV biology and function from the labratory to thepatient in the clinic. Invited speakers represent world leading scientists in the field including ProfessorMatthew JA Wood from the Department of Physiology, Anatomy and Genetics at University of Oxford. Prof.Wood is a worldleading scientist in developing RNAbased therapies for neurological diseases. He hasdeveloped systems for creating engineered exosomes which can target specific molecules to the brain,which paves the way for generating targetspecific exosomebased therapies. The course including lectures,workshops and discussions will be scheduled full time from Monday to Friday in "Cellen", Hälsovägen 79,Novum Huddinge. Time to prepare the individual examinations will be given during two days the followingweek.
Kursansvarig : Nina HeldringInstitutionen för [email protected]
Karolinska Institutet HERM, Novum
14157Huddinge
Kontaktpersoner : Samir ElAndaloussiInstitutionen för laboratoriemedicin
Samir.El[email protected]
Title : Biomedical Ecology The microbiota in health and disease
Kursnummer : 2861Antal högskolepoäng : 1.5Datum : 20151123 20151127Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Microbiology, Tumor and Cell BiologiSärskild behörighet : Kursens lärandemål : After finishing the course the student should be able to show knowledge about: the composition and function of the intestinal microbiota and its cross talk with the host. the establishmentof the microbiota during different stages of life, and its impact on the development and function of theimmune system and host tissues. the role of how an altered intestinal function and dysbiosis might occurin connection with different diseases/disturbances. The student should be able to show insight in: methods to study the intestinal microbiota as well as data analyses and interpretation. the microbiota asthe largest metabolic organ in the body and its physiological and pathophysiological role in health anddisease. the role of the hostmicroflora crosstalk for the intestinal ecology/homeostasis. Kursens innehåll : The course will cover the aspects of the composition and function of the intestinalmicrobiota from birth, during life and the ageing period, how it might be influenced by diet and disease, andhostmicrobe crosstalk. Sequencing techniques will be introduced for the study the microflora and comparedto biochemical methods. Novel findings will be discussed by lecturers in the research frontline on thetranslational topics of normal flora in relation to inflammatory bowels diseases (IBD), irritable bowelssyndrome (IBS) celiac disease, reumatological and neurophysiological diseases. The course will be suitablefor clinical and preclinical PhD students and researchers where the microbiota is of significance, includingareas such as allergy, asthma, systemic autoimmune diseases, cardiovascular diseases, obesity,rheumatology, neurophysiological disturbances such as autism spectrum disorders, chronic fatigue, nutrition including effects of pre and probiotics, diabetes, metabolic syndrome, infectious diseases andbioinformatics. The course replaces the previous course 2300. Arbetsformer : The course will combine lectures, student work shops and student seminars, and practicallaboratory work lectures by well established frontline researchers in their respective fields. laboratoryexperiments on the students own intestinal flora. work shops/combined with focused literature studieswithin defined areas which will be summarized in terms of student seminars. flipped class room and peerlearning using the competence of the course attendees. Examination : Summative examination includes laboratory work and student presentations that areevaluated by the respective tutor at the specific course module and written examination of the coursecontent by multiplechoice questions covering all topics discussed. Obligatoriska moment : Laboratory work and student workshops and seminars. Participants that areabsent from the laboratory part and seminars will have to present a written paper on the subject. Antal studenter : 12 24Urval av studenter : Selection will be based on the relevance of the course syllabus for the applicant'sdoctoral project (according to written motivation). Övrig information :
Kursansvarig : Åsa SjölingInstitutionen för mikrobiologi, tumör och cellbiologi08524 875 [email protected]
Kontaktpersoner : Katrin PütsepInstitutionen för mikrobiologi, tumör och cellbiologi
Title : Regulatory RNAs in Development, Disease and Evolution
Kursnummer : 2865Antal högskolepoäng : 2.0Datum : 20151007 20151016Språk : EngelskaNivå : Doctoral levelKursansvarig institution : Department of Medical Biochemistry and BiophysicsSärskild behörighet : Kursens lärandemål : After completing the course, the students should be able to: describe thedifferent kinds of regulatory RNAs in development, disease and evolution, and their mechanism of action describe and critically evaluate the application of emerging experimental strategies for the study ofregulatory RNAs transfer the knowledge acquired in the course into their specific projects and fields ofresearch. Kursens innehåll : The course will cover key concepts concerning regulatory RNAs and their mechanismsof action. The following themes will be covered: Different kinds of regulatory (noncoding) RNAs ineukaryotes, regulatory RNAs in development and disease, regulatory RNAs in virus and bacteria, evolutionof regulatory RNAs, RNA dynamics and RNA methodologies (bioinformatics and emerging experimentalstrategies). Arbetsformer : The learning activities include lectures, seminars, group discussions and presentations. Thestudents will present themselves with short chalk talks on the first day. They will be divided into groups andwill have several sessions designated for groups discussions and brainstorming to transfer and apply thenew knowledge acquired during the course into their specific projects and fields of research. Each group willpresent and discuss their conclusions from these discussions to all the other students and course directors.Examination : Examination according to the intended learning outcomes of the course will take place inform of a presentation, where the course participants will discuss the transfer of the knowledge acquiredduring the course into their specific projects and fields of research. Each course participant will be assessedindividually. Obligatoriska moment : Lectures, seminars, group discussions and presentations are mandatory.Compensation in case of absence according to the instructions of the course director.Antal studenter : 15 30Urval av studenter : The selection is based on relevance of the course content for their doctoral projectand the personal motivation included in the course application.Övrig information : The course is full time. Most of the course lectures will be given at the main seminarroom at the Scheele building, Department of Medical Biochemistry and Biophysics (A3 311). The studentswill participate in a Karolinska Institutet conference on Regulatory RNAs and Chromatin at the Nobel Forum,October 16th 2015, with the following speakers confirmed: Leonie Ringrose, Institute of MolecularBiotechnology, Vienna, Austria, Johan Jakobsson, Lund University, John Rinn, Harvard University, USA,Raffaella Santoro, University of Zurich, Switzerland, Marcel Dinger, Garvan Institute of Medical Research,Sidney, Australia and Tony Kouzarides, University of Cambridge, United Kingdom. The course is jointlyorganized by Karolinska Institutet and Uppsala University and cofunded by the doctoral programme inRegenerative medicine, doctoral programme in Cell Biology and Genetics (seehttps://internwebben.ki.se/en/doctoralprogrammes0) and DBRM (www.dbrm.se). <br>This course haspreviously been given as a one week course (1,5 hp), course number 2698.
Kursansvarig : Goncalo CasteloBrancoInstitutionen för medicinsk biokemi och biofysik
Goncalo.Castelo[email protected]
Kontaktpersoner :