“case study: strategy in action; mexico, universal health coverage; and what’s posible!”

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    Cancer and children:

    Strategy in Action

    NCD Child Conference

    Oakland CA, March 21st

    Felicia Marie KnaulHarvard Global Equity Initiative,

    Global Task Force on Expanded Access to Cancer Care and

    Control in Low and Middle Income Countries

    Mexican Health Foundation

    Tmatelo a pecho

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    From anecdote

    to evidence

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    Global Task Force on Expanded

    Access to Cancer Care and

    Control in Developing Countries

    = global health + cancer care

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    Closing the Cancer Divide:A Blueprint to Expand Access in LMICs

    I: Much should be doneII: Much could be done

    III: Much can be done

    1: Innovative Delivery

    2: Access to Affordable Medicines,

    Vaccines & Technologies

    3: Innovative Financing: Domesticand Global

    4: Evidence for Decision-Making

    5: Stewardship and Leadership

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    Applies a diagonal

    approach to avoid

    the false dilemmasbetween disease silos

    -CD/NCD- thatcontinue to plague

    global health

    Closing the Cancer Divide:A BLUEPRINT TO EXPAND ACCESS IN LMICs

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    Challenge and disprove the

    myths about

    cancer/NCD/Chronic illness

    M1. Unnecessary

    M2. Unaffordable

    M3. Impossible

    M4: Inappropriate

    Should,

    Could, and

    Can..

    be done

    Expanding access to cancer care and control in

    low and middle income countries:

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    Mirrors the overall epidemiological

    transitionprotracted and polarized*:

    LMICs increasingly face both cancersassociated with infection, and all other

    cancers.

    Cancers that were once considered only ofthe poor, now cease to be the only cancers

    of the poor. (e.g. cervical & breast cancer)

    The Cancer Transition

    * Frenk et al

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    Cancer is a disease of both rich and poor;

    yet it is increasingly the poor who suffer:

    1. Exposure to risk factors

    2. Preventable cancers (infection)

    3. Death and disability fromtreatable cancer

    4. Stigma and discrimination

    5. Avoidable pain and suffering

    The Cancer Divide:

    An Equity Imperative

    Fac

    ets

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    Top 10 causes of Mortality in children

    under 15 years by income regions

    Communicable, maternal, perinatal and nutritional conditions

    Noncommunicable diseases

    InjuriesSource: Own estimates based on data from WHO, Global Health observatory.

    Low Lower middle Upper middleInfectious and parasitic dis. Perinatal conditions Perinatal conditions

    Perinatal conditions Infectious and parasitic dis. Infectious and parasitic dis.Respiratory infections Unintentional injuries Congenital anomaliesUnintentional injuries Respiratory infections Unintentional injuriesCongenital anomalies Congenital anomalies Respiratory infections

    Nutritional deficiencies Digestive dis. Malignant neoplasmCardiovascular dis. Nutritional deficiencies Respiratory dis.

    Digestive dis. Cardiovascular dis. Nutritional deficienciesNeuropsychiatric

    conditionsMalignant neoplasm Neuropsychiatric conditions

    Malignant neoplasm Endocrine disorders Cardiovascular dis.

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    Distribution of mortality, 1-15

    years Mexico, 1979-2008

    Malignant tumors

    Respiratory infections

    Infectious and parasitic diseases

    Injuties

    Congenital anomalies

    0%

    10%

    20%

    30%

    40%

    1979

    2008

    1-4

    0%

    10%

    20%

    30%

    40%

    1979

    2008

    5-14

    Malignant tumors

    5%

    16%

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    Adults

    Leukaemia

    All cancers

    Source: Knaul, Arreola, Mendez. estimates based on IARC, Globocan, 2010.

    Children

    LOW

    INCOME

    HIGH

    INCOME

    Sur

    vival

    inequa

    litygap

    LOW

    INCOME

    HIGH

    INCOME

    100%

    The Opportunity to Survive (M/I)

    Should Not Be Defined by Income

    In Canada, almost 90% of children with

    leukemia survive.

    In the poorest countries only 10%.

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    Stigma:Chronic diseases and

    disability add a layer of

    discrimination onto ethnicity,

    poverty, and gender.

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    The most insidious example of

    injustice is access to pain controlNon-methadone, Morphine

    Equivalent opioid consumption per

    death from HIV or cancer in pain

    Poorest 10%: 54 mg;

    Richest 10%: 97,400 mg

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    A) Should be done:

    B) Could be done:

    C) Can be done

    Myth 1. Unnecessary

    Myth 2. Inappropriate

    Myth 3. Unaffordable

    Myth 4: Impossible

    Expanding access to cancer

    care and control in LMICs:

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    The Diagonal Approach to

    Health System Strengthening

    Rather than focusing on disease-specific vertical

    programs or only on horizontal system

    constraints, harness synergies that provideopportunities to tackle disease-specific priorities

    while addressing systemic gaps.

    Optimize available resources so that the whole ismore than the sum of the parts.

    Bridge the divide as patients suffer diseases over a

    lifetime, most of it chronic.

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    Diagonal Strategies:

    Positive ExternalitiesPromoting prevention and healthy lifestyles:

    Reduce risk for cancer and many other diseases

    Promoting access to education for children w CI

    Reduces poverty, contributes to social developmentIntroducing child cancer treatment

    Improves hygiene and reduce intra-hospital infections

    Social insurance for childrenKick-starts broader social insurance for populations

    Pain control and palliation

    Reducing barriers to access is essential for cancer, for

    other diseases, and for surgery.

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    A) Should be done: necessary

    and appropriate

    B) Could be done:

    C) Can be done

    Myth 3. Unaffordable

    Myth 4: Impossible

    Expanding access to cancer

    care and control in LMICs:

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    Investing in.

    We Cannot Afford Not To

    Health is an investment, not a cost

    Tobacco is a huge economic risk:

    3.6% lower GDP

    Total economic cost of cancer, 2010:

    2-4% of global GDP

    Prevention and treatment offers potential world

    savings of $ US 131-850 billion mostly due to

    productivity gains and reducing suffering

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    Avoidable childhood cancer deaths

    from Leukemia by income region

    Income Region LethalityAvoidable deaths

    Social justice/3

    Low income 0.73 0.45

    Lower middleincome

    0.72 0.38

    Upper middle

    income0.57 0.35

    High income 0.18 0.08

    1/3-1/2 of cancer deaths are avoidable:

    2.4-3.7 million deaths

    Of which 80% are in LIMCs

    I i I CCC

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    Investing In CCC:

    The costs to close the cancer divide

    may be less than many fear:All but 3 of 29 LMIC priority, candidate cancer

    chemo and hormonal agents are off-patent: many