Skosana KC, Kekana TDepartment of Anatomical Pathology,

University of Limpopo (MEDUNSA CAMPUS)

Overview of Bladder Carcinoma~ All arise from urothelial lining Urothelial Ca.(TCC) - 90% all bladder

cancersSCC – 5 %Adeno.Ca < 2 % < 3 % Non-Urothelial - Neuroendocrine Carcinoma - Leiomyosarcoma (a tumor arising from

smooth muscle) - Metastatic (Lymphoma ,Malignant

melanoma etc )University of Limpopo – MEDUNSA CAMPUS 2

Neuroendocrine carcinoma - Bladder Carcinoid tumors Large cell neuroendocrine carcinomas, andSmall cell carcinomas.Male patients & coexist with urothelial

carcinomaSmall Cell Ca (SCC) of the urinary bladder

was first described by Koss in 1975.SCC account for 0.5–0.7% of primary bladder

tumours.

OBJECTIVES:A case report of a 40 year old female with a

bladder tumour.A transurethral resection of the tumour was

performed and the specimen was sent for histopathology assessment.

Chest X-rays : Normal

Gross

We received numerous fragments of brownish tissue fragments in fixed 10 % formalin .

The largest fragment measured 20 x 10 x 10mm

D.DxNested Variant of Urothelial Cell Carcinoma

(TCC)Small Cell Carcinoma of the BladderSarcomatoid urothelial carcinomaMetastatic CarcinomaLymphoma

Our Case Report

CONCLUSION Like SCLC, SCC of the urinary bladder is an

aggressive tumour.

It has characteristic histological, & IHC features .

These aid in differentiating it from high-grade TCC and lymphoma.

References CytoJournal 2005, 2:18

doi:10.1186/1742-6413-2-18The article is available from:

http://www.cytojournal.com/content/2/1/18 Arch Pathol Lab Med—Vol 126, October 2002

2 0 0 4 B J U I N T E R N A T I O N A L | 9 4 , 1 2 – 1 7 |

Our Case Report