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Cascade of HIV Care in the Netherlands from 2002 to 2013. Esther Engelhard 14th European AIDS Conference October 18, 2013 Disclosed no conflict of interest.

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Page 1: Cascade of HIV Care in the Netherlands from 2002 to 2013. Esther Engelhard 14th European AIDS Conference October 18, 2013 Disclosed no conflict of interest

Cascade of HIV Care in the Netherlands from 2002 to 2013.

Esther Engelhard

14th European AIDS Conference October 18, 2013

Disclosed no conflict of interest.

Page 2: Cascade of HIV Care in the Netherlands from 2002 to 2013. Esther Engelhard 14th European AIDS Conference October 18, 2013 Disclosed no conflict of interest

HIV infected

Virally suppressed

Diagnosed Linked to care

Retained in care

On ART

35.3 million

10.6 million

1) Cascade of care in the Netherlands

2) Influence of hospital characteristics on cascade

Page 3: Cascade of HIV Care in the Netherlands from 2002 to 2013. Esther Engelhard 14th European AIDS Conference October 18, 2013 Disclosed no conflict of interest

Background (1)

HIV in the Netherlands 17,006 HIV patients in clinical care 1100 new patients in care in 2012

Page 4: Cascade of HIV Care in the Netherlands from 2002 to 2013. Esther Engelhard 14th European AIDS Conference October 18, 2013 Disclosed no conflict of interest

Background (2)

HIV care General health care: health insurance obligatory 26 legally acknowledged HIV treatment centres Standards determined by field experts Criteria:

Treatment centre HIV treating physician Specialised HIV/AIDS nurse

≥ 2 HIV treating physicians

≥ 1 Specialised nurse

≥ 160 patients

≥ 20 new patients per year

Multidisciplinary team meetings

National surveillance

Access scientific literature

Infectious disease specialist

HIV/AIDS Experience

≥ 80 patients in care

≥ 10 new patients per year

Training

Registration as specialised HIV/AIDS nurse (or)

HIV/AIDS Experience

HIV/AIDS Masterclass

Page 5: Cascade of HIV Care in the Netherlands from 2002 to 2013. Esther Engelhard 14th European AIDS Conference October 18, 2013 Disclosed no conflict of interest

Q-HIV study

Cascade of care HIV care engagement in the Netherlands: 2002 - 2013 Influence hospital characteristics:

Centre size: number of patients in care

Number of patients per HIV treating physician

Treatment centre HIV treating physician Specialised HIV/AIDS nurse

≥ 2 HIV treating physicians

≥ 1 Specialised nurse

≥ 160 patients

≥ 20 new patients per year

Multidisciplinary team meetings

National surveillance

Access scientific literature

Infectious disease specialist

HIV/AIDS Experience

≥ 80 patients in care

≥ 10 new patients per year

Training

Registration as specialised HIV/AIDS nurse (or)

HIV/AIDS Experience

HIV/AIDS Masterclass

Page 6: Cascade of HIV Care in the Netherlands from 2002 to 2013. Esther Engelhard 14th European AIDS Conference October 18, 2013 Disclosed no conflict of interest

Methods (1)

Study population HIV-1-infected patients, enrolled in 2002 or later ≥18 years at time of HIV diagnosis Alive and residing in the Netherlands

Definitions Linked to care: study population Retained in care: evidence of being in care after Jan 1,

2012 On ART: started with ART Virally suppressed: <100 copies/mL

Page 7: Cascade of HIV Care in the Netherlands from 2002 to 2013. Esther Engelhard 14th European AIDS Conference October 18, 2013 Disclosed no conflict of interest

Methods (2)

Stratification Centre size:

Small: ≤500 patients in care. Large: >500 patients in care.

Patients per physician:≤ 80 patients per physician81-200 patients per physician>200 patients per physician

Page 8: Cascade of HIV Care in the Netherlands from 2002 to 2013. Esther Engelhard 14th European AIDS Conference October 18, 2013 Disclosed no conflict of interest

Results (1)

Overall Linked to care: 13,166 Retained in care: 93% Receiving ART: 79% Virally suppressed:70%

Page 9: Cascade of HIV Care in the Netherlands from 2002 to 2013. Esther Engelhard 14th European AIDS Conference October 18, 2013 Disclosed no conflict of interest

Results (2)

Stratified by treatment centre size:No difference

Page 10: Cascade of HIV Care in the Netherlands from 2002 to 2013. Esther Engelhard 14th European AIDS Conference October 18, 2013 Disclosed no conflict of interest

Results (3)

Stratified by no. of patients per physician:No difference

Page 11: Cascade of HIV Care in the Netherlands from 2002 to 2013. Esther Engelhard 14th European AIDS Conference October 18, 2013 Disclosed no conflict of interest

Discussion (1) Previously published data

- Retained in Care: 56% - 68% - On cART: 41% - 50%- Virally suppressed: 32% - 38%

Our data: 93%; 79%; 70%: relatively high

Possible explanations: Accessibility health care access Legal regulation of care; criteria HIV treatment centres;

monitoring

XX

X

Source: Mugavero et al, 2013

Page 12: Cascade of HIV Care in the Netherlands from 2002 to 2013. Esther Engelhard 14th European AIDS Conference October 18, 2013 Disclosed no conflict of interest

Discussion (2)

Challenges: Diagnose HIV-infected population Linkage to care diagnosed patients

73%

HIV Infected

Page 13: Cascade of HIV Care in the Netherlands from 2002 to 2013. Esther Engelhard 14th European AIDS Conference October 18, 2013 Disclosed no conflict of interest

Conclusions

Relatively high percentage of retention, ART use and viral suppression

No difference between small and large centres (Early) diagnosis and linkage to care remain a challenge

Page 14: Cascade of HIV Care in the Netherlands from 2002 to 2013. Esther Engelhard 14th European AIDS Conference October 18, 2013 Disclosed no conflict of interest

Acknowledgements Stichting HIV Monitoring Ard van Sighem Q-HIV study group:

Frank KroonColette SmitPythia NieuwkerkMarlies HulscherPeter ReissKees BrinkmanSuzanne Geerlings

Aids Fonds

Page 15: Cascade of HIV Care in the Netherlands from 2002 to 2013. Esther Engelhard 14th European AIDS Conference October 18, 2013 Disclosed no conflict of interest