cardiovascular biomechanics - tu/e · / department of biomedical engineering / cardiovascular...

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Master Program Information Cardiovascular Biomechanics Dr.ir. A.C.B. Bogaerds Prof.dr.ir F.N. van de Vosse Dr.ir. E.M.H. Bosboom Prof.dr. N.H.J. Pijls Dr.ir. P.H.M. Bovendeerd Prof.dr.mr.dr. B.A.J.M. de Mol Dr.ir. M.C.M. Rutten Characteristics of our work Mathematical and computational modeling of complex fluid-structure interaction problems Validation of computational models through advanced experimental methods Determination of mechano-biological properties of cardiovascular tissue and blood Development of sophisticated measurement techniques for laboratory and clinical use Application of computer simulations in clinical diagnostics and intervention Research areas Hemodynamics Cardiovascular mechanics, growth and remodeling Cardiovascular instrumentation, prostheses, and devices / department of biomedical engineering / cardiovascular biomechanics and devices Clinical cardiovascular research Master courses Cardiovascular Fluid Mechanics Modeling of Cardiac Function Pathophysiology of the Circulation Cardiovascular Fluid Structure Interaction Fluid Biomechanics Vascular Mechanics

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Page 1: Cardiovascular Biomechanics - TU/e · / department of biomedical engineering / cardiovascular biomechanics properties tissue adaptation and growth electro-mechanical coupling Applications

Master Program Information

Cardiovascular BiomechanicsDr.ir. A.C.B. Bogaerds

Prof.dr.ir F.N. van de Vosse Dr.ir. E.M.H. Bosboom

Prof.dr. N.H.J. Pijls Dr.ir. P.H.M. Bovendeerd

Prof.dr.mr.dr. B.A.J.M. de Mol Dr.ir. M.C.M. Rutten

Characteristics of our workMathematical and computational modeling of

complex fluid-structure interaction problems

Validation of computational models through

advanced experimental methods

Determination of mechano-biological properties

of cardiovascular tissue and blood

Development of sophisticated measurement

techniques for laboratory and clinical use

Application of computer simulations in clinical

diagnostics and intervention

Research areasHemodynamics

Cardiovascular mechanics, growth and

remodeling

Cardiovascular instrumentation, prostheses,

and devices

/ department of biomedical engineering / cardiovascular biomechanics

and devices

Clinical cardiovascular research

Master coursesCardiovascular Fluid Mechanics

Modeling of Cardiac Function

Pathophysiology of the Circulation

Cardiovascular Fluid Structure Interaction

Fluid Biomechanics

Vascular Mechanics

Page 2: Cardiovascular Biomechanics - TU/e · / department of biomedical engineering / cardiovascular biomechanics properties tissue adaptation and growth electro-mechanical coupling Applications

Cardiovascular Biomechanics

Master Program Information

Hemodynamics / Arjen Bogaerds

Basic investigationscomputational fluid structure

interaction

hydrodynamic instabilities

dynamics of blood coagulation

vortex dynamics

non-linear convection-diffusion

circulatory physiology

Cardiovascular mechanics, growth and remodeling / Peter Bovendeerd

Basic investigationsfrom tissue properties to

organ function

characterization of tissue

myo

fib

er

ven

tric

le

str

ess

[kP

a]

p

ressu

re [

kP

a]

str

ess

[kP

a]

ma

x p

ressu

re [

kP

a]

sh

ort

en

ing

[k

Pa

]

str

oke

vo

lum

e [m

l]

+9% +12%

adaptation of myofber orientation

Applicationsaneurysms, heart valves

atherosclerosis, thrombosis

Student activitiesmathematical analysis of

transport phenomena

finite element modeling

laboratory experiments

/universities : Sheffield, London, Oxford, Milano /clinic : Maastricht, Eindhoven, Rotterdam /industry : Philips Health Care / Research

/ department of biomedical engineering / cardiovascular biomechanics

properties

tissue adaptation and growth

electro-mechanical coupling

Applicationsheart failure, aneurysms

resynchronization

coronary stents

student activitiesfinite element modeling

analysis of animal / clinical

data (MRI, ultrasound)

laboratory experiments

placenta

myo

fib

er

ven

tric

le

str

ess

[kP

a]

p

ressu

re [

kP

a]

volume [ml] adaptation time [-] adaptation time [-]

strain [-] adaptation time [-] adaptation time [-]ma

xstr

ess

[kP

a]

ma

x p

ressu

re [

kP

a]

sh

ort

en

ing

[k

Pa

]

str

oke

vo

lum

e [m

l]

mean: +10%

sd: -38%

mean: +6%

sd: -60%

/universities : Maastricht, San Diego, Auckland /clinic : Eindhoven, Maastricht, Utrecht /industry : Philips Health Care, Medtronic, Cordis

Page 3: Cardiovascular Biomechanics - TU/e · / department of biomedical engineering / cardiovascular biomechanics properties tissue adaptation and growth electro-mechanical coupling Applications

Cardiovascular Biomechanics

Master Program Information

Cardiovascular instrumentation, prostheses, and devices / Marcel Rutten

Basic investigationsphysical principles of

measurement methods

modeling of the circulation

Applicationscoronary catheterization

cardiac assist devices

ultrasonic vascular diagnosis

Clinical cardiovascular research / Mariëlle Bosboom

Basic investigationspathology of cardiovascular

diseases

patient specific modeling of

ultrasonic vascular diagnosis

Student activitiesmodeling of physiological

systems

laboratory experiments

data acquisition and analysis

design of experiments and

devices

modeling of experiments

/universities : Delft, Gent, Maastricht, London, Parijs /clinic : Maastricht, Eindhoven /industry : Philips Research, Radi, Esaote,

/ department of biomedical engineering / cardiovascular biomechanics

patient specific modeling of

the (diseased) cardiovascular

system

clinical measurement

methods

applied medical imaging

Applicationsaneurysms, heart failure

vascular access

Student activitiespatient specific modeling

analysis of clinical data

clinical measurements

/universities : Utrecht, Amsterdam, Maastricht /clinic : Maastricht, Eindhoven, Houston, Utrecht /industry : Philips Health Care, Esaote