14. Thermocyclers

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EuroCyclers EuroClone’s EuroCyclers are the new line of thermal cycler offered by EuroClone: reliable instruments at an affordable price! These thermalcyclers are available in a wide range of configurations allowing for many different applications and meeting the requirements of every

Technical SpecificationsTemp range 4-99°CHeating rate > 4°CCooling rate > 4°CBlock temp uniformity < 0,2°CBlock temp accuracy < 0,1°C Temp of hot lid 20-110°CGradient range 1-30°C (only with 96G and 384G thermalblocks)Program storage >100 programs + unlimited if using external USB memoryMax cycles # 99Display 320 x 240 LCD; 3,8”Interfaces USB, LANPower Supply AC110-220; 50 Hz; 600WSize (w x l x h) 36,8 x 25 x 28,5 cmWeight 10 Kg

Cat. DescriptionEMTCE EuroCycler FLEXEMB48D EuroCycler Flex48EMB3048 EuroCycler Flex3048EMB384 EuroCycler Flex384GEMB96G EuroCycler Flex96GEMB4I EuroCycler FlexSitu

lab! From top-of-the-line multiblock instruments like the EuroCycler FLEX, sporting 5 different blocks allowing for ad-hoc configuration, from the dual 48 wells block to the in situ PCR block, down to the small EuroCycler Mini, a small 24 wells personal cycler with unprecedented ramping speed (5°C/s)!

EuroCycler FLEX

EuroCycler FLEX is a modular system composed by a base instrument and several “user switchable” thermalblocks letting every user choose his own configuration.

The available blocks are: • Dual Block: 48 x 0,2 ml + 48 x 0,2 ml (6 x 8 strip; 48 x 0,2 ml)• 30/48 wells mixed block: 48 x 0,2 ml or 30 x 0,5 ml (4 x 12-strip; 48 x 0,2ml; 30 x 0,5 ml)• High Throughput 384 wells Gradient Block: 384-microplate full-skirted • 96 wells Gradient Block: 96 well microplate (full-skirted); 12 x 8 strip; 96 x 0,2 ml• In Situ PCR Block: 4 x standard in situ plates

The EuroCycler FLEX is completed by a control software that allows the creation and management of protocols via a networked PC. This also allows to control and monitor up to 30 thermalcyclers via a LAN connection.

FeaturesLow noise (only 59 dB)Easy to use graphical interface software for rapid programming and data management. Large LCD Display: 320 x 240Compact design for easy installation and transportUp to 30 thermalcycler can be controlled via LAN network.Aluminium ThermalblockStore more than 100 user defined PCR protocols in internal memory (unlimited if using an external USB memory or networked PC)Touch down PCR protocolsAutorestart after power failurePassword setting for conditional accessSample volume can be set to optimize thermal protocolAdjustable Hot-LidHeating and Cooling Ramping rate up to 4°C

Thermal GradientThis feature (available only with the Flex96G and Flex384G thermalblocks) allows to optimize PCR protocols by setting a temperature gradient during annealing. EuroCyclers allow the creation of thermally-optimized and faster protocols, by letting users set a gradient also during elongation and denaturation steps.

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Eurocycler Gradient 96

Eurocycler Gradient 96 is the most widely used format with its block housing 96 0.2ml tubes or one 96 wells full-skirted plates.

FeaturesEasy to use graphical interface software for rapid programming and data management. Large LCD Display: 320 x 240Compact design for easy installation and transportUp to 30 thermalcycler can be controlled via LAN network.Aluminium ThermalblockStore more than 100 user defined PCR protocols in internal memory (unlimited if using an external USB memory or networked PC)Touch down PCR protocolsAutorestart after power failurePassword setting for conditional accessSample volume can be set to optimize thermal protocolAdjustable Hot-LidHeating and Cooling Ramping rate up to 4°C

Thermal GradientThis feature allows to optimize PCR protocols by setting a temperature gradient during annealing. EuroCyclers allow the creation of thermally-optimized and faster protocols, by letting users set a gradient also during elongation and denaturation steps.

Technical SpecificationsTemp range 4-99°CHeating rate > 4°CCooling rate > 4°CBlock temp uniformity < 0,2°CBlock temp accuracy < 0,1°C Temp of hot lid 30-110°CGradient range 1-30°C Program storage >100 programs + unlimited if using external USB memoryMax cycles # 99Display 320 x 240 LCD; 5,7”Interfaces USB, LANPower Supply AC110-220; 50 Hz; 600WSize (w x l x h) 34,5 x 25 x 27 cmWeight 10 Kg

Cat. DescriptionEMTC96GHBA EuroCycler Gradient 96

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EuroCycler Mini

EuroCycler Mini is a small personal thermalcycler, with very high performances. It has the highest ramping speed for personal thermalcylcers, with heating up to 5°C/sec, which, along the full-graphic interface for programming, makes it one of the fastest and easiest to use thermalcyclers.

FeaturesEasy to use graphical interface software for rapid programming and data management. Large LCD Display: 320 x 240Aluminium ThermalblockStore more than 100 user defined PCR protocols in internalAutorestart after power failurePassword setting for conditional accessSample volume can be set to optimize thermal protocolAdjustable Hot-LidHeating and Cooling Ramping rate up to 5°C

Technical SpecificationsTemp range 4-99°CHeating rate > 5°CCooling rate > 4°CBlock temp uniformity < 0,3°CBlock temp accuracy < 0,3°C Temp of hot lid 30-110°CProgram storage 100 programsMax cycles # 99Display 320 x 240 LCD; 3,8”Power Supply AC220; 50 Hz; 200WSize (w x l x h) 29,7 x 21,2 x 20 cm Weight 3,2 Kg

Cat. DescriptionEMTC24HB EuroCycler Mini

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peqSTARpeqSTAR is a high performance range of Thermocyclers with PCR technology designed for the 21st century. The combination of high specification engineering and superior system control enable powerful, fast ramping, stable temperature control and a high level of system reliability. The ‘touchscreen’ control, USB ports, LAN connection and the universal block for 0.2 ml and 0.5 ml tubes result in unique ease of use. Various interchangeable blocks (96 Wells, 384 Wells, in situ or High Pressure Lid) are available for the peqSTAR Thermocyclers.The new peqSTAR 2X is a double block cycler with two independent operable

48 well blocks offering maximum flexibility in the smallest space. This further development of the well-proven peqSTAR Thermocyclers provides both the best technical specifications and also very simple of use, e.g. the FlexGradient™ Technology, emulation mode, ‘peqSTAR Manager’ PC software, etc. One-Personal offers approved technology and the highest precision for your daily laboratory work. With its small footprint it is a reliable cycler for small sample numbers.

peqSTAR - EuroClone

With its sleek design, the peqSTAR Universal 96, including the universalblock system for both 0.2 ml and 0.5 ml tubes, plates and strips, sets thenew standard for thermocycling with unmatched system performance,quality and capabilities.

FeaturesWide coloured touchscreen displayHigh speed: 5 °C/secUniversal block: 96 x 0.2 ml; 48 x 0.5 mlUniformity: +/- 0.25 °C6 peltier, 6 sensor system4 USB portsNetwork connectivitySoftware for Tm and protocols calculation includedGLP reportReal-time visualization of temperaturesPCR licensed

Technical Specifications Six powerful Peltier elements with Long Life Technology Increment/decrement temperature: 0.1 to 9.9 °C Six control circuits with PT 1000 thermal probes Temperature range heated lid: 70 to 120 °C Max. heating and cooling rate: 5 °C/s Programmable lid locking Block uniformity (at 72 °C): ± 0.25 °C 4 x USB, 1 x Ethernet port (MS Windows®) Temperature range thermoblock: 4 to 105 °C Dimensions (W x H x D): 29 x 31 x 36 cm Regulating accuracy: ± 0.1 °C Weight incl. block: 13 kg Adjustable ramping: 0.1 to 2.0 °C/s Power consumption: 850 VA Increment/decrement time: 0:01 to 9:59 minutes Power supply: 90 – 260 V AC, 50 – 60 Hz

Gradient feature (optional)Maximum Gradient over 12 columns: 39.8°C (± 19.9°C)Temperature range, gradient: 35-105°CGradient accuracy: ± 0.1 °CUpgradeability on-the-spot

Cat. DescriptionEM95-95002 EuroClone peqSTAR 96 UniversalEM95-96002 EuroClone peqSTAR 96 Universal Gradient

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peqSTAR 2X - EuroClone

The new peqSTAR 2X double block system with its two independently operable 48 well blocks in one unit is the answer for maximum flexibility for a busy lab.

Features Outstanding speed, dependable PCR results, easy to use and a construction that will last − all essentials for your hunt for the perfect cycler. The peqSTAR 2X double block system fulfills all these requirements and is loaded with new technologyFlexGradient™ Technology: Perfect linear gradients or independent lane control Modern user interface with new functions: graphical programming, ‘Global Program Ramp’, ‘Gradient Control’, emulation mode etc. Latest technology for great new featuresRemote control and monitoring of instruments via PC software MP3 signal tones User calls via email Master/Slave control of instruments, optionally with wireless operation

Technical Specifications 8 Peltier elements per block with Long Life Technology 8 control circuits per block with PT1000 thermal probes Maximum heating and cooling rate: 5 °C/s Block uniformity (at 72 °C): ± 0.2 °C Regulating accuracy: ± 0.1 °C Adjustable ramping: 0.1 to 3.0 °C/s (For single steps or the whole protocol) Increment/decrement time: 0:01 to 9:59 minutes Increment/decrement temperature: 0.1 to 9.9 °C Temperature range heated lid: 40 to 120 °C Programmable lid locking Internal memory for 500.000 typical PCR protocols in unlimited, selfcreated directories/subfolders Block capacity:2 universal blocks for 48 x 0.2 ml tubes or 24 x 0.5 ml tubes with flat caps each 4 x USB, 1 x Ethernet port GLP reports for the continuous recording of all runs Dimensions (W x H x D):30 x 28 x 38 cm Weight incl. blocks: 13 kg Power consumption: 850 VA

One-Personal

One-Personal is distinguished by efficient run times, excellent PCR performance and easy-to-use operation all in a conveniently compact footprint.

FeaturesUniversal block for up to 25 x 0.2 ml tubes or 13 x 0.5 ml tubes with flat caps Self-adjusting heated lid Small footprint (22.5 x 25 x 28 cm) Immensely flexible programming allowing for Touch-Down and Long-Range PCR Manufactured in Germany under ISO 9001 and ISO 13485 conditions Fully licensed for PCR

Technical Specifications Peltier element with Long Life Technology and PT 1000 high quality thermal probe Temperature range: 4 to 105 °C Regulating accuracy: ± 0.1 °C Block uniformity (at 72 °C): ± 0.7 °C Heating and cooling rate: 2 °C/s Max. program number: 90 (with up to 99 steps/program) Increment/decrement time: 0:01 to 9:59 minutes Increment/decrement temperature: 0.1 to 9.9 °C Block capacity:Universal block for 25 x 0.2 ml tubes or 13 x 0.5 ml tubes with flat capsHeatable selfadjusting lid Temperature range heated lid:70 to 120 °C Interfaces: Centronics (parallel) and RS232 (serial)

Gradient FunctionMaximum gradient over 8 rows: 30.0 °C Temperature range gradient: 35 to 105 °C FlexGradient™ Technology HGradient upgradeability on-the-spot

Cat. DescriptionEM95-08002 EuroClone peqSTAR 2X Gradient Thermocyclers

GLP report for complete recording of all runs Dimensions (W x H x D): 22.5 x 25 x 28 cm Weight incl. block: 6.3 kg Max. power consumption: 120 VA

Cat. DescriptionEM95-4002 EuroClone One-Personal