7/24/2019 Calvert+Formula+Worksheet

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Calvert Formula Worksheet

(140-age) X wt in kg * (X 0.85 in women) = GFR (Cockcroft & Gault Method)

72 X serum creatinine

(Can use Creatinine Clearance for GFR if new one is available)

(GFR + 25) X AUC = dose in mg

Warning: This can be an overestimation in obese patients with subsequent overdosage

Target AUC (mg/ml X min) depends on previous treatment and combinationchemotherapy. Physician makes this determination.

Target AUC Chemo Combo Previous Treatment6 to 8 no combination no

4 to 6 no combination yes

4 to 6 combination with Cytoxin no

You Need:• Patient age = _______ • Patient Weight In Kg* = ________• * Measured Weight in pounds = _________ Divided by Wt in kg = _______ Kg • Male or Female? _______ • Serum Creatinine = _________ • AUC (ordered by MD) = _________

{140 - (pt age)} X (wt in kg) (X 0 .85 if female) = ___________(GFR)72 X ________ (serum creatinine)

{_____(GFR) + 25} X ______(AUC) = ________ mg (dose ordered)

Nurse giving chemo: ___________________________________________

Nurse checking chemo: _________________________________________