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Brighton, February 1 st , 2013 1 st Project Management Committee

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Brighton, February 1st, 2013

1st Project Management Committee

Program of the morning

• Introduction of the participants

• Short presentation of the Interreg program

• Short presentation of the PeReNE project

• Presentation of the PeReNE website (Yacine)

• Presentation of Presage main functions (Yacine)

• Preparation of 1st payment claim

• Deliverables and activity report

• Communication rules

• Questions to Mr Samuel Lesart

Short presentations

• Michel Boitel (Presentation of the Improve project)

• Alison Edwards

• Jean Luc Henrioul (Root Lines Technology)

• Benjamin Corgier (Axoscience)

• Thierry Jouenne

• Pietro Ghezzi

• Discussion on the project and proposed activities for the next 6 months

• Short visit of the front sea and dinner in Brighton (6 PM to 10 PM)

Program of the afternoon

Short presentation of the Interreg program

(Part of the documents provided by Interreg on January 16th, Meeting: ‘Making a success of you project’

Trans Channel Cooperation project before all

La coopération entre la France et la Grande-Bretagne

Cooperation between France and United-Kingdom

Ce programme s'inscrit dans le cadre de la politique de cohésion de l'Union Européenne, au titre de

l'objectif « coopération territoriale européenne »

This programme is part of the European cohesion policy, within the « european territorial cooperation objective »

Favoriser l’émergence d’un espace de citoyenneté communeTo promote the emergence of a common space of citizenship

AXE 2 - Tisser despartenariats d'acteurspour le développementéconomique et les pôlesd'excellence transfrontaliers

Priority 2 – Build partnershipsfor crossbordereconomic development andcentres of excellence

AXE 3 – Construire unespace communattractif pour y vivre etpour le visiter

Priority 3 – Build anattractive region to livein and visit

AXE 4 - Assurer ledéveloppement durableenvironnemental del’espace commun

Priority 4 – Ensure aSustainable environmentaldevelopment of thecommon space

AXE 1 - Renforcer le sentiment d'appartenance à un espace commun et laconscience d'intérêts partagés

Priority 1 – Reinforce the sense of belonging to a common space ofcitizenship and raise awareness of common interests

Les acteurs du programme Interreg IVA

Actors of the Interreg IVA programme

Comité de programmation

Steering Committee

PeReNE Autorité de gestion

Managing authority

Comité de suivi

Monitoring Committee

Secrétariat technique

conjoint

Joint technical

secretariat

Autorité de certification

Certifying authority

Autorité d’audit

Audit authority

Autorité de

gestion

Managing

authority

Convention

FEDER

ERDF contract

Bénéficiaire unique - chef de file

Single beneficiary - lead partner

Convention partenariale

Partnership agreement

Partenaires

Partners

Secrétariat

Technique

Conjoint

Joint Technical

Secretariat

Les acteurs du programme Interreg IVA

Actors of the Interreg IVA programme

Copy

Copy

Taux global de programmation FEDER

General ERDF programming level

89,89%

0% 10% 20% 30% 40% 50% 60% 70% 80% 90% 100%

TOTAL : 168 135 002 €

151 144 457,08 € FEDER Programmé

Programmed ERDF

117

projets approuvés

projects approved

Short presentation of the PeReNE project

www.perene-project.eu

Total budget: 5.58 million euro including 2.79 millions euros of ERDF

15 partners

Teams involved in PeReNE

23 research teams, 3 core facilities, 2 SMEs & Cosmetic Valley

Research Teams, Technological

Infrastructures, SMEs and

Associations

Organizations LocationReferent for the

project

LP - Univ Rouen

PP2 - INSERM

LP -Univ Rouen

PP2 -INSERM

3

Génomique fonctionnelle et

physiopathologie neuronale et

neuroendocrine, INSERM U982

LP -Univ Rouen Rouen Anouar Youssef

4 Neovas LP - Univ Rouen Rouen Philippe Leroux

5 ADEN, INSERM U1073 LP - Univ Rouen Rouen Coeffier Moise

6 Laboratoire glycomev LP - Univ Rouen Rouen Driouich Azeddine

8Equipe de Chimie bioorganique,

UMR CNRS 6014LP - Univ Rouen Rouen Renard Pierre Yves

Laboratoire de Microbiologie

Signaux et Microenvironnement

(LMSM)

LP - Univ Rouen Evreux Lesouhaitier Olivier

10 BRICs, IMR CNRS 6270 PP3 - CNRS Rouen Jouenne Thierry

11 LaTIM, INSERM U1101- PP4 - Université de Bretagne

Occidentale de BrestBrest Le Mevel Jean Claude

12 DDT

PP5 - University of

Portsmouth Higher Education

Corporation

PortsmouthEugen Barbu and Darek

Gorecki

13 SMT

PP5 - University of

Portsmouth Higher Education

Corporation

Portsmouth Tim Clark

14 SOP

PP5 - University of

Portsmouth Higher Education

Corporation

Portsmouth Alex Ford

Research Teams, Technological

Infrastructures, SMEs and

Associations

Organizations LocationReferent for the

project

15Division of Clinical and

Laboratory Investigation

PP6 - The University of

SussexBrighton Ghezzi Pietro

16 CERMNPP7 - Université de Caen

Basse-Normandie (UCBN)Caen Bureau Ronan

17

Unité de Biologie des Plantes et

Contrôle des Insectes

Ravageurs

PP8 - Université de Picardie

Jules VerneAmiens Boitel Michèle

18Laboratoire d'Ecotoxicologie -

Milieux Aquatiques (LEMA)PP9 - Université du Havre Le Havre Knigge Thomas

19 Biocatalysis Centre PP 10 - University of Exeter Exeter Harmer Nicholas

20 School of Pharmacy PP11 - University of Brighton Brighton Gard Paul

21 Computational Modelling GroupPP12 - University of

SouthamptonSouthampton Jonathan Essex

22Chemistry and Drug Delivery,

Medway School of PharmacyPP13 - University of Kent Kent Edwards Alison

23 PRIMACEN Platform PP2- INSERM Rouen Galas Ludovic

24 PISSARO Platform PP2– Inserm Rouen Chan Philippe

25 Proteomics Platform Biogenouest PP2- INSERM Rennes Pineau Charles

27 Root Lines Technology PP14 - Root Lines Technology Amiens Henrioul Jean-Luc

28 BioSIMS Technologies PP15 - BioSIMS Technologies Rouen Heuclin Christine

29 Cosmetic Valley PP17 - Cosmetic Valley Chartres Masson Christophe

1

Neurotrophic and Neuronal

differentiation Team, INSERM

U982

Vaudry David

2

Astrocyte et Niche Vasculaire

dans la Différenciation et la

Tumorigenèse Gliale, INSERM

U982

Castel Hélène

Rouen

Rouen

Research Teams, Technological

Infrastructures, SMEs and

Associations

Organizations LocationReferent for the

project

LP - Univ Rouen

PP2 - INSERM

LP -Univ Rouen

PP2 -INSERM

3

Génomique fonctionnelle et

physiopathologie neuronale et

neuroendocrine, INSERM U982

LP -Univ Rouen Rouen Anouar Youssef

4 Neovas LP - Univ Rouen Rouen Philippe Leroux

5 ADEN, INSERM U1073 LP - Univ Rouen Rouen Coeffier Moise

6 Laboratoire glycomev LP - Univ Rouen Rouen Driouich Azeddine

8Equipe de Chimie bioorganique,

UMR CNRS 6014LP - Univ Rouen Rouen Renard Pierre Yves

Laboratoire de Microbiologie

Signaux et Microenvironnement

(LMSM)

LP - Univ Rouen Evreux Lesouhaitier Olivier

10 BRICs, IMR CNRS 6270 PP3 - CNRS Rouen Jouenne Thierry

11 LaTIM, INSERM U1101- PP4 - Université de Bretagne

Occidentale de BrestBrest Le Mevel Jean Claude

12 DDT

PP5 - University of

Portsmouth Higher Education

Corporation

PortsmouthEugen Barbu and Darek

Gorecki

13 SMT

PP5 - University of

Portsmouth Higher Education

Corporation

Portsmouth Tim Clark

14 SOP

PP5 - University of

Portsmouth Higher Education

Corporation

Portsmouth Alex Ford

Research Teams, Technological

Infrastructures, SMEs and

Associations

Organizations LocationReferent for the

project

15Division of Clinical and

Laboratory Investigation

PP6 - The University of

SussexBrighton Ghezzi Pietro

16 CERMNPP7 - Université de Caen

Basse-Normandie (UCBN)Caen Bureau Ronan

17

Unité de Biologie des Plantes et

Contrôle des Insectes

Ravageurs

PP8 - Université de Picardie

Jules VerneAmiens Boitel Michèle

18Laboratoire d'Ecotoxicologie -

Milieux Aquatiques (LEMA)PP9 - Université du Havre Le Havre Knigge Thomas

19 Biocatalysis Centre PP 10 - University of Exeter Exeter Harmer Nicholas

20 School of Pharmacy PP11 - University of Brighton Brighton Gard Paul

21 Computational Modelling GroupPP12 - University of

SouthamptonSouthampton Jonathan Essex

22Chemistry and Drug Delivery,

Medway School of PharmacyPP13 - University of Kent Kent Edwards Alison

23 PRIMACEN Platform PP2- INSERM Rouen Galas Ludovic

24 PISSARO Platform PP2– Inserm Rouen Chan Philippe

25 Proteomics Platform Biogenouest PP2- INSERM Rennes Pineau Charles

27 Root Lines Technology PP14 - Root Lines Technology Amiens Henrioul Jean-Luc

28 BioSIMS Technologies PP15 - BioSIMS Technologies Rouen Heuclin Christine

29 Cosmetic Valley PP17 - Cosmetic Valley Chartres Masson Christophe

1

Neurotrophic and Neuronal

differentiation Team, INSERM

U982

Vaudry David

2

Astrocyte et Niche Vasculaire

dans la Différenciation et la

Tumorigenèse Gliale, INSERM

U982

Castel Hélène

Rouen

Rouen

• Begining of the project: 01/02/2012

Preparation phase : deliverable = application form

• Approval: 11/10/2012

Beginning of activities (≈ 2 years)

• End of the project: 30/03/2015

All our expenditures must be paid before this date.

• Administrative closure: 30/06/2015

Timing of PeReNE

Objectives of PeReNE

Aim of the project:

To place the trans channel area at the forefront of peptide research

5 main objectives of the project:

1) Develop new skills for peptide research

2) Conduct 14 collaborative cross-border research topics

3) Organize scientific meetings and trainings

4) Increase interactions with biotechs from the pharma, cosmetic

and food industries

5) Communicate towards the lay public

Aim of the program:

Build partnerships between players involved in cross-border economic development, and between centres of excellence

Activities of the PeReNE project 31 activities Deliverables for each activity 1 referent of each activity: are names OK? Several partners involved in each activity Start and end date

• Approval Letter: 1) Explain why our project was approved: (number of

partners involved, transchannel cooperation, links with other interreg projects, involves SMEs…).

2) Includes some requests: - establish contacts with IMPROVE platform and

laboratoire Génétique Moléculaire et Génétique Epidémiologique de l'Université de Bretagne Occidentale

- develop links with SMEs on the British side (point to discuss in the afternoon)

- 2 payment claim / year

Request from Interreg Steering Committee

Presentation of the PeReNE website (Yacine)

http://perene-project.eu/

Change Language

Log-in

PeReNE Project Website

Who has an account ?

54 accounts so far

Administration part

Will be moderated by the manager

You can upload PDF, DOC, XLS files

You can create an account for a user of your team

You can record all the exchanges you have done during the project

All your activities related to the project can be record as a deliverables Automatically uploaded in the database for activity report

You can update the information of your team

Information part

Each news can be writen in English and French, if you need a French

translation, please contact us.

Directly pasted from a word doc

Paste an url of an image from a website or from the documentation section

Upload directly a photo from the editor to display on the news

Paste an url of a document for download

Information part

You can select the recipients you want to contact by type and/or by

partner

Submission button => have to be moderated

Edit a newsletter

Documentation part

Upload several files at once by clicking on ‘Upload’ button

Manage the document like the Windows Explorer

User account

You can create an account only for your team(s) and your partner(s)

Appear on the contact page

Select the status for the newsletter recipient type

Team information

Information to generate a page that will present your team, your

activity and main publications

Team information

Specify the collaborations with other teams of the projet =>

map of interaction

Automatically get information on PubMed from the PMID =>

automatically formatted

Ex: Map of LARC-Neurosciences Network

Team information

Collaboration extractor

Click on a spot to view the teams localized in a

city and click on a link to view the team informations

Deliverables Type and title of the deliverable

Each recorded deliverable will automatically increment the

number of deliverables

Activity Report automatically

generated

Picture is the recommended format => Directly inserted into the activity

report

Deliverables

6 elements to record a deliverable

You can view all your deliverables. The pictures are

included directly in the activity report

Manager access

Presentation of Presage main functions (Yacine)

Follow the financial aspects of the project

Add financial information and the communication aspect

Each partner will have to complete this part.

Presage- Adding expenditures

How to add an expenditure ?

Presage- Validation of expenditures

Validation by the Partner

Validation by the project leader

Expenditure settlement certificates/Attestations

d'acquittement

Validation by your accounting officer or

accountant

Has to validate the link of the expenditure with the

project

Each partner has to fill on Presage the

‘Expenditure settlement certificates’ and

have it signed by accounting officer or

accountant

Presage- Validation of expenditures

Provide your deliverables To be uploaded on the PERENE web site:

http://www.perene-project.eu/

Send the hard copies (3 copies) to the lead partner

1 for the lead partner, 1 for the

auditor, 1 for the JTS

Validation by the Partner

Validation by the project leader

Expenditure settlement certificates/Attestations

d'acquittement

Validation by your accounting officer or

accountant

Has to validate the link of the expenditure with the

project

Each partner has to fill on Presage the

‘Expenditure settlement certificates’ and

have it signed by its accounting officer or

accountant

+ Progress report On presage

Rapport d'avancement/ Progress report

Rapport d'avancement/ Progress report

Reminds our objectives, team involved….

Rapport d'avancement/ Progress report

Deliverables: will be completed by the lead partner according

to the information you will have provided in the PeReNE

website.

Comments can be added if necessary or if changes occur

Rapport d'avancement/ Progress report

Will be implemeted according to the figures uploaded by each partner.

Has to match with our planned budget.

Comments about the budget of this action, Other comments on administrative

and financial management

Rapport d'avancement/ Progress report

All important meetings have to be registered. Has to be completed by lead partner. Please do not forget to provide the information: Meeting date Action it relates to Subject of the meeting Attendence sheet List of participants Minutes of the meeting

Explain actions adopted in order to fulfil

information and publicity requirements in

conformity to Regulation EC N°

1083/2006 of the European Commission

(put in annex publicity documents, such

as pictures, brochures,…)

indicate any difficulties

encountered, delays in project

implementation, any comment you

would like the Monitoring

Committee to be informed of.

Indicate, if necessary, any project

amendments impacting on the project

implementation (deadline for

implementation…) and any

modification budget. briefly justify the

requests.

Preparation of 1st payment claim

Timing

Payment

claim

number

Payment claim

sent to JTS by

Supporting

Documents sent by

Lead Partner to the

auditor by

Supporting

documents sent to LP

and PRESAGE filled

in by partners by

Expenses defrayed between Total expenses

1 mai-13 avr-13 mars-13 / fevrier 2012/ --> /fevrier 2013 / 1 221 358,41 €

2 nov-13 oct-13 sept-13 /mars 2013/ --- >/aout 2013/ 1 554 646,41 €

3 mai-14 avr-14 mars-14 /septembre 2013/ ---> /fevrier 2014/ 1 168 305,73 €

4 nov-14 oct-14 sept-14 /mars 2014/ --- > /aout 2014/ 1 168 305,73 €

5 mai-15 avr-15 mars-15 /septembre 2014/ ---> /fevrier 2015/ 474 363,24 €

1 221 358 € of expenditures to declare by the end of february 2013 !

Do not forget to count your time for the preparation (David V = 9000 €)

End March 2013 -> Presage filled + supporting documents to LP

End April 2013 –> Suporting documents sne

End May 2013 -> Payment clail to JTS

Respect of the calenders (time and amounts)

Average under consomption of 25%

Lost of funding:

• 5.5 Million € in 2011

• 7.2 Million € in 2012

Expenses by partner by the end of February

• Rouen University: 340 112 € • CNRS: 27 000 € • INSERM: 293 350 € • Caen University: 35 000 € • Brest University: 41 811,99 € • Root Lines Technology: 28 675 € • BioSIMS Technologies: 9 000 € • Cosmetic Valley: 6 580 € • University of Picardie: 19 500 € • Le Havre University: 19 500 € • Portsmouth University: 190 000 € • Sussex University: 52 839,50 € • Brighton University: 63 170 € • Exeter University: 24 399,72 € • Southampton University: 28 320,50 € • Kent University: 27 305,70 €

1 221 358,41 of expenses (ERDF: 610 841,71 €) by the end of February 2013

1 554 646,41 of expenses (ERDF: 762 985,71 €) by the end of August 2013

Financial statement by the end of 2013

Redistribution between teams and partners if necessary

Demande de paiement

Payment claim

STC

JTS

Contrôle

1er

niveau

1st level

control

chef de

file

project

leader

P1

P2

Cdf

certification

certification

certification

chef de

file

project

leader co

ntr

ôle

Versement de la subvention

Grant payment

Autorité de

gestion

Managing authority

STC

JTS

CDC

autorité de

paiement

paying

authority

chef de file

project leader

€ P2

P3

P1

Documents justificatifs / Supporting documents

for :

Frais de salaire / Staff costs

Frais généraux / Overheads

Frais de déplacements / Travel costs

Amortissement / Depreciation

Contributions en nature / In kind expenses

Dépenses éligibles

Eligible expenditure

Salariés des partenaires

Staff employed by partners

Bulletins de salaire / Payslips

Livre de paye / Payroll

Feuilles de temps (temps partiel) /

Timesheets (part-time)

Contrats (temps plein) / Contracts (full time)

Frais de salaire / Staff costs

Frais de personnel par partenaire

= temps en heures x taux horaire

Staff costs by partner

= time in hours x hourly cost

Salaire éligible : brut + charges patronales

Eligible salary : gross + employer’s

contributions

Frais de salaire / Staff costs

Frais de salaire / Staff costs

Feuille de temps / Timesheet

Coûts réels / Real costs

Basés sur comptes certifiés n-1 /

Based on certified accounts n-1

Max. 25% budget projet global

Max. 25% total project budget

Frais généraux / Overheads

Méthode calcul validée par STC

et annexée à la convention FEDER

Calculation method validated by JTS

and appended to ERDF Grant Offer Letter

Frais généraux / Overheads

Factures ou feuilles de remboursement /

Invoices or refund sheets

Ordre de mission / Travel requests

Ordre du jour + compte-rendu / Agenda + minutes

Liste des participants ou feuille de présence

List of participants or attendance sheet

Programme de l’événement / Event programme

Présentation Powerpoint ou supports exposés

Powerpoint slides or documents exhibited

Frais de déplacement / Travel costs

3 grands principes

3 main principles

Liberté d’accès / Free access

Egalité / Equality

Transparence / Transparency

Mise en concurrence / Competitive tendering

Lors de contrôles, fournir :

For any controls, provide:

Règlement intérieur / Internal rules

Pas de règlement intérieur ? /

No internal rules?

REGLE = DEMANDER 3 DEVIS !

RULE = ASK FOR 3 QUOTES

Mise en concurrence / Competitive tendering

Pour tout partenaire / For any partner

Contrôles de second niveau

Second-level controls

Contrôles qualité par l’Autorité de Certification (CDC)

Controls by the Certifying Authority (CDC)

Contrôles par l’Autorité d’Audit (CICC)

Controls by the Audit Authority (CICC)

Contrôles par la Commission Européenne et l’OLAF

Controls by the European Commission and OLAF

Des contrôles à plusieurs niveaux

Controls at several levels

Deliverables and activity report

User guide for time sheets

Activities related to PeReNE

Start date 01/02/2012

End date 30/06/2015

Timeline

Phase / Action

Phase1: Project Preparation

1. Preparation of the project and

assembly of the application1 Application form

Phase2:Coordination and

communication

2.1. Administrative coordination 5 Meetings:April 2013, October 2013, March 2014, September 2014, January 2015

2.2. Communication toward the lay

public

2.3. Communication toward the

industry

2.4. Scientific meetings and training 1 Meeting Nov 14th, 2012, 15 Conferences, 1 Training, 1 Final conference

Phase 3: Research topics

3.1. Research topic 1: Peptide

characterization6 Protocols, 2 Conferences, 3 Posters

3.2. Research topic 2 : In planta

peptide production4 Protocols, 2 Publications, 5 Posters

3.3. Research topic 3: Peptide

delivery through skin, gut and brain

blood barriers

4 Protocols, 3 Publications , 10 Posters

3.4. Research topic 4: Peptide

conformation and peptidomimetics4 Protocols, 2 Publications, 6 Posters

3.5. Research topic 5: Peptides and

memory functions2 Protocols, 1 Publications, 5 Posters

3.6. Research topic 6:Central and

peripheral peptidergic control of

cardiovascular and ventilatory

activities and effects of endocrine

disruptors

2 Protocols, 1 Publications, 8 Peptides, 4 Posters

3.7. Research topic 7: Involvment of

peptides in bacterial resistance 1 Publications, 2 Protocols, 2 Posters

3.8. Research topic 8: Targeting of

chemotactic vasoactive peptide

receptor signaling in neurovascular

diseases

2 Protocols, 1 Posters, 3 Posters

Phase 4: Administrative and financial

closure

4. Administrative and financial

closure of the project

1 Press release, 1 Final

report

2012 2013 2014 2015

5 Operation to promote peptide R&D in Cosmetic field, 1 Presentation at ConneXions R&D (Cosmet Valley), 6

Participation to Business lounges with cosmetic Valley, 1 Focus on the PeReNE project in CBS Letter, 1 Promotion of

the project in a bilingual press release, 1 Record of competence, 5 Invitation of SMEs from pharmceutical industry

1 Web site, 8 Newsletters, 10 Press releases on web sites and in various media, 6 Participation at Science festival, 1 visit for lay

public and 4 conferences

Deliverables related to PeReNE

Some deliverables related to coordination and communication

Some deliverables related to research projects

Each team will have to upload its deliverables on the PeReNE website

Short text + proof

Snapshot, photo, PDF… with logo

PeReNE website (log in)

Can be put in the news section and/or deliverables section

Eddition of a newsletter on peptide research and of a newsletter of the IBiSa

Platforms of High-Normandy Bilingual 8 letters July 2013 September 2013 January 2014 May 2014 September 2014 January 2015 May 2015 July 2015

+ English version

Newsletter of the IBiSa Platforms

Newsletter on Peptide Reseach

Concept?

1) News related to peptide R&D (symposium, conferences…)

2) Recruitments on the PeReNE project 3) 16 activities related to research project & methodological development -> 2 focus / issue (calender?) Other ideas?

Promotion of the project

Upload yours on the website Add news on the website

Press release

Communication rules

Action à destination du PUBLIC:

«Le projet X a été sélectionné dans le cadre du programme

européen de coopération transfrontalière INTERREG IV A

France (Manche) – Angleterre, cofinancé par le FEDER.»

Initiatives intended for the PUBLIC:

«The project X was selected under the European cross-border

cooperation programme INTERREG IV A France (Channel) –

England, co-funded by the ERDF.»

Obligations en matière d’information

Your obligations in terms of publicity

- Pour toutes vos actions:

1. Emblème de l'UE / EU emblem

2. «Fonds Européen de développement Régional»,

«European Regional Development Fund»

3. «L’Union Européenne investit dans votre avenir »,

«The European Union. Investing in Your Future»

Utilisez le bloc-marque du programme: il réunit les 3 éléments !

Use the block-mark of the programme: it combines the 3 elements!

Sauf pour les petits

objets

promotionnels

---

Except for small promotionnal items

Obligations en matière d’information (suite)

Your obligations in terms of publicity

1

2

3

Communication rules Communication rules

1/ Proposed activities for the next 6 months 2/ How to develop links with SMEs? 3/ Date & location for 2nd Project Management Committee ? Proposal October 23 afternoon in Rouen 4/ Date & location for other Project Management Committees ? Proposals?