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Page 1: discoverytekcapital.com/wp-content/uploads/2017/07/Non-Invasive-Glucose-T… · BREATH GLUCOSE MONITOR Glucose is a non-volatile molecule found in exhaled breath condensates. Accurately

discovery A BETTER WAY TO MEASURE GLUCOSE

FOR DIABETICS

Page 2: discoverytekcapital.com/wp-content/uploads/2017/07/Non-Invasive-Glucose-T… · BREATH GLUCOSE MONITOR Glucose is a non-volatile molecule found in exhaled breath condensates. Accurately

Glucose Breathalyzer

Measures glucose concentration in exhaled breath. Ideal

for screening sessions in clinics, hospitals, ER centers,

doctor’s offices and schools.

Developed at Purdue University, USA, patent pending

The World Health Organization estimates that diabetes mellitus is the

eighth largest cause of death globally with the diseases fastest growth

rate in the developed regions of the world. There are 29.1 million

Americans living with diabetes which leads to a 50% higher risk of death

in adults.

Monitoring blood glucose is one crucial aspect of diabetes management.

Currently, monitoring blood glucose requires direct FDA-approved

measurement from a blood sample, using a lance, strips and glucometer.

This inconvenient and invasive monitoring technique often discourages

patients from making the frequent measurements needed for careful

regulation of glucose.

The next generation for diabetic monitoring: painless measurement

Page 3: discoverytekcapital.com/wp-content/uploads/2017/07/Non-Invasive-Glucose-T… · BREATH GLUCOSE MONITOR Glucose is a non-volatile molecule found in exhaled breath condensates. Accurately

Available for Immediate License

Only from Tekcapital®

.

For additional information contact:

Dr. Michael Kayat

Vice President

[email protected]

+1 305 200 3450 x 303 (office)

At the forefront of discovery

INNOVATION FOR SAFE, ACCURATE

AND PAINLESS DIABETES

MANAGEMENT

BREATH GLUCOSE MONITOR

Glucose is a non-volatile molecule found in exhaled breath

condensates. Accurately measuring the concentration of

glucose in exhaled breath may allow non-invasive

estimation of glucose concentration in blood, which in turn

could be used for routine monitoring of the blood glucose

concentration in diabetic patients. Currently, there is no

commercially available device to collect exhaled breath

condensate and measure its glucose level.

HO W IT WO RKS The glucose monitor consists of a

breath condensing unit that monitors the temperature,

volume, and glucose concentration of exhaled breath along

with a condenser for background air. The glucose

concentration of exhaled breath condensate is corrected

for the humidity and glucose concentration of background

air in order to deliver more reliable measurements

compared to those of similar technologies. The blood

glucose concentration is calculated from its correlation with

the corrected glucose concentration in the exhaled breath

condensate with fluorescent spectroscopy.

ADVANT AG ES The advantages of this technology are

that the sensor system does not require blood samples

while simultaneously reducing measurement complications

that may result from humidity and glucose in air.

SALIVA GLUCOSE METER

Glucose is present in saliva at low concentrations. The

device allows trace fluid samples from a biological surface to

be obtained for electrochemical analysis and the subsequent

detection of analytes. The device can be used to collect fluid

from the mouth and for such samples to be subsequently

processed to detect glucose, a metabolic product in saliva,

using disposable biosensor strips.

HO W IT WO RKS The device has a collections chamber

containing an absorbent hydrogel material with a connected

microfluidic channel. A sensing chamber is connected to the

channel that allows saliva samples to be extracted. The

sensing chamber contains an enzyme that detects the

glucose through electrochemistry. The glucose concentration

is calculated from the current generated in the biosensor

strip.

ADVANT AG ES The advantages of this technology are

that the sensor is quick, easy to use, does not require blood

samples and operates in a similar way to the current FDA-

approved blood glucose strips. The technique is very

sensitive and only needs very small saliva samples. The

strips can be manufactured in high volumes at low cost using

screen-printed thick films.Available for Immediate License

Only from Tekcapital®

.

For additional information contact:

Dr. Michael Kayat

Vice President

[email protected]

+1 305 200 3450 x 303 (office)

At the forefront of discovery

INNOVATION FOR SAFE, ACCURATE

AND PAINLESS DIABETES

MANAGEMENT

BREATH GLUCOSE MONITOR

Glucose is a non-volatile molecule found in exhaled breath

condensates. Accurately measuring the concentration of

glucose in exhaled breath may allow non-invasive

estimation of glucose concentration in blood, which in turn

could be used for routine monitoring of the blood glucose

concentration in diabetic patients. Currently, there is no

commercially available device to collect exhaled breath

condensate and measure its glucose level.

HO W IT WO RKS The glucose monitor consists of a

breath condensing unit that monitors the temperature,

volume, and glucose concentration of exhaled breath along

with a condenser for background air. The glucose

concentration of exhaled breath condensate is corrected

for the humidity and glucose concentration of background

air in order to deliver more reliable measurements

compared to those of similar technologies. The blood

glucose concentration is calculated from its correlation with

the corrected glucose concentration in the exhaled breath

condensate with fluorescent spectroscopy.

ADVANT AG ES The advantages of this technology are

that the sensor system does not require blood samples

while simultaneously reducing measurement complications

that may result from humidity and glucose in air.

SALIVA GLUCOSE METER

Glucose is present in saliva at low concentrations. The

device allows trace fluid samples from a biological surface to

be obtained for electrochemical analysis and the subsequent

detection of analytes. The device can be used to collect fluid

from the mouth and for such samples to be subsequently

processed to detect glucose, a metabolic product in saliva,

using disposable biosensor strips.

HO W IT WO RKS The device has a collections chamber

containing an absorbent hydrogel material with a connected

microfluidic channel. A sensing chamber is connected to the

channel that allows saliva samples to be extracted. The

sensing chamber contains an enzyme that detects the

glucose through electrochemistry. The glucose concentration

is calculated from the current generated in the biosensor

strip.

ADVANT AG ES The advantages of this technology are

that the sensor is quick, easy to use, does not require blood

samples and operates in a similar way to the current FDA-

approved blood glucose strips. The technique is very

sensitive and only needs very small saliva samples. The

strips can be manufactured in high volumes at low cost using

screen-printed thick films.Available for Immediate License

Only from Tekcapital®

.

For additional information contact:

Dr. Michael Kayat

Vice President

[email protected]

+1 305 200 3450 x 303 (office)

At the forefront of discovery

INNOVATION FOR SAFE, ACCURATE

AND PAINLESS DIABETES

MANAGEMENT

BREATH GLUCOSE MONITOR

Glucose is a non-volatile molecule found in exhaled breath

condensates. Accurately measuring the concentration of

glucose in exhaled breath may allow non-invasive

estimation of glucose concentration in blood, which in turn

could be used for routine monitoring of the blood glucose

concentration in diabetic patients. Currently, there is no

commercially available device to collect exhaled breath

condensate and measure its glucose level.

HO W IT WO RKS The glucose monitor consists of a

breath condensing unit that monitors the temperature,

volume, and glucose concentration of exhaled breath along

with a condenser for background air. The glucose

concentration of exhaled breath condensate is corrected

for the humidity and glucose concentration of background

air in order to deliver more reliable measurements

compared to those of similar technologies. The blood

glucose concentration is calculated from its correlation with

the corrected glucose concentration in the exhaled breath

condensate with fluorescent spectroscopy.

ADVANT AG ES The advantages of this technology are

that the sensor system does not require blood samples

while simultaneously reducing measurement complications

that may result from humidity and glucose in air.

SALIVA GLUCOSE METER

Glucose is present in saliva at low concentrations. The

device allows trace fluid samples from a biological surface to

be obtained for electrochemical analysis and the subsequent

detection of analytes. The device can be used to collect fluid

from the mouth and for such samples to be subsequently

processed to detect glucose, a metabolic product in saliva,

using disposable biosensor strips.

HO W IT WO RKS The device has a collections chamber

containing an absorbent hydrogel material with a connected

microfluidic channel. A sensing chamber is connected to the

channel that allows saliva samples to be extracted. The

sensing chamber contains an enzyme that detects the

glucose through electrochemistry. The glucose concentration

is calculated from the current generated in the biosensor

strip.

ADVANT AG ES The advantages of this technology are

that the sensor is quick, easy to use, does not require blood

samples and operates in a similar way to the current FDA-

approved blood glucose strips. The technique is very

sensitive and only needs very small saliva samples. The

strips can be manufactured in high volumes at low cost using

screen-printed thick films.Available for Immediate License

Only from Tekcapital®

.

For additional information contact:

Dr. Michael Kayat

Vice President

[email protected]

+1 305 200 3450 x 303 (office)

At the forefront of discovery

INNOVATION FOR SAFE, ACCURATE

AND PAINLESS DIABETES

MANAGEMENT

BREATH GLUCOSE MONITOR

Glucose is a non-volatile molecule found in exhaled breath

condensates. Accurately measuring the concentration of

glucose in exhaled breath may allow non-invasive

estimation of glucose concentration in blood, which in turn

could be used for routine monitoring of the blood glucose

concentration in diabetic patients. Currently, there is no

commercially available device to collect exhaled breath

condensate and measure its glucose level.

HO W IT WO RKS The glucose monitor consists of a

breath condensing unit that monitors the temperature,

volume, and glucose concentration of exhaled breath along

with a condenser for background air. The glucose

concentration of exhaled breath condensate is corrected

for the humidity and glucose concentration of background

air in order to deliver more reliable measurements

compared to those of similar technologies. The blood

glucose concentration is calculated from its correlation with

the corrected glucose concentration in the exhaled breath

condensate with fluorescent spectroscopy.

ADVANT AG ES The advantages of this technology are

that the sensor system does not require blood samples

while simultaneously reducing measurement complications

that may result from humidity and glucose in air.

SALIVA GLUCOSE METER

Glucose is present in saliva at low concentrations. The

device allows trace fluid samples from a biological surface to

be obtained for electrochemical analysis and the subsequent

detection of analytes. The device can be used to collect fluid

from the mouth and for such samples to be subsequently

processed to detect glucose, a metabolic product in saliva,

using disposable biosensor strips.

HO W IT WO RKS The device has a collections chamber

containing an absorbent hydrogel material with a connected

microfluidic channel. A sensing chamber is connected to the

channel that allows saliva samples to be extracted. The

sensing chamber contains an enzyme that detects the

glucose through electrochemistry. The glucose concentration

is calculated from the current generated in the biosensor

strip.

ADVANT AG ES The advantages of this technology are

that the sensor is quick, easy to use, does not require blood

samples and operates in a similar way to the current FDA-

approved blood glucose strips. The technique is very

sensitive and only needs very small saliva samples. The

strips can be manufactured in high volumes at low cost using

screen-printed thick films.Available for Immediate License

Only from Tekcapital®

.

For additional information contact:

Dr. Michael Kayat

Vice President

[email protected]

+1 305 200 3450 x 303 (office)

At the forefront of discovery

INNOVATION FOR SAFE, ACCURATE

AND PAINLESS DIABETES

MANAGEMENT

BREATH GLUCOSE MONITOR

Glucose is a non-volatile molecule found in exhaled breath

condensates. Accurately measuring the concentration of

glucose in exhaled breath may allow non-invasive

estimation of glucose concentration in blood, which in turn

could be used for routine monitoring of the blood glucose

concentration in diabetic patients. Currently, there is no

commercially available device to collect exhaled breath

condensate and measure its glucose level.

HO W IT WO RKS The glucose monitor consists of a

breath condensing unit that monitors the temperature,

volume, and glucose concentration of exhaled breath along

with a condenser for background air. The glucose

concentration of exhaled breath condensate is corrected

for the humidity and glucose concentration of background

air in order to deliver more reliable measurements

compared to those of similar technologies. The blood

glucose concentration is calculated from its correlation with

the corrected glucose concentration in the exhaled breath

condensate with fluorescent spectroscopy.

ADVANT AG ES The advantages of this technology are

that the sensor system does not require blood samples

while simultaneously reducing measurement complications

that may result from humidity and glucose in air.

SALIVA GLUCOSE METER

Glucose is present in saliva at low concentrations. The

device allows trace fluid samples from a biological surface to

be obtained for electrochemical analysis and the subsequent

detection of analytes. The device can be used to collect fluid

from the mouth and for such samples to be subsequently

processed to detect glucose, a metabolic product in saliva,

using disposable biosensor strips.

HO W IT WO RKS The device has a collections chamber

containing an absorbent hydrogel material with a connected

microfluidic channel. A sensing chamber is connected to the

channel that allows saliva samples to be extracted. The

sensing chamber contains an enzyme that detects the

glucose through electrochemistry. The glucose concentration

is calculated from the current generated in the biosensor

strip.

ADVANT AG ES The advantages of this technology are

that the sensor is quick, easy to use, does not require blood

samples and operates in a similar way to the current FDA-

approved blood glucose strips. The technique is very

sensitive and only needs very small saliva samples. The

strips can be manufactured in high volumes at low cost using

screen-printed thick films.Available for Immediate License

Only from Tekcapital®

.

For additional information contact:

Dr. Michael Kayat

Vice President

[email protected]

+1 305 200 3450 x 303 (office)

At the forefront of discovery

INNOVATION FOR SAFE, ACCURATE

AND PAINLESS DIABETES

MANAGEMENT

BREATH GLUCOSE MONITOR

Glucose is a non-volatile molecule found in exhaled breath

condensates. Accurately measuring the concentration of

glucose in exhaled breath may allow non-invasive

estimation of glucose concentration in blood, which in turn

could be used for routine monitoring of the blood glucose

concentration in diabetic patients. Currently, there is no

commercially available device to collect exhaled breath

condensate and measure its glucose level.

HO W IT WO RKS The glucose monitor consists of a

breath condensing unit that monitors the temperature,

volume, and glucose concentration of exhaled breath along

with a condenser for background air. The glucose

concentration of exhaled breath condensate is corrected

for the humidity and glucose concentration of background

air in order to deliver more reliable measurements

compared to those of similar technologies. The blood

glucose concentration is calculated from its correlation with

the corrected glucose concentration in the exhaled breath

condensate with fluorescent spectroscopy.

ADVANT AG E S The advantages of this technology are

that the sensor system does not require blood samples

while simultaneously reducing measurement complications

that may result from humidity and glucose in air.

SALIVA GLUCOSE METER

Glucose is present in saliva at low concentrations. The

device allows trace fluid samples from a biological surface to

be obtained for electrochemical analysis and the subsequent

detection of analytes. The device can be used to collect fluid

from the mouth and for such samples to be subsequently

processed to detect glucose, a metabolic product in saliva,

using disposable biosensor strips.

HO W IT WO RKS The device has a collections chamber

containing an absorbent hydrogel material with a connected

microfluidic channel. A sensing chamber is connected to the

channel that allows saliva samples to be extracted. The

sensing chamber contains an enzyme that detects the

glucose through electrochemistry. The glucose concentration

is calculated from the current generated in the biosensor

strip.

ADVANT AG ES The advantages of this technology are

that the sensor is quick, easy to use, does not require blood

samples and operates in a similar way to the current FDA-

approved blood glucose strips. The technique is very

sensitive and only needs very small saliva samples. The

strips can be manufactured in high volumes at low cost using

screen-printed thick films.Available for Immediate License

Only from Tekcapital®

.

For additional information contact:

Dr. Michael Kayat

Vice President

[email protected]

+1 305 200 3450 x 303 (office)

At the forefront of discovery

INNOVATION FOR SAFE, ACCURATE

AND PAINLESS DIABETES

MANAGEMENT

BREATH GLUCOSE MONITOR

Glucose is a non-volatile molecule found in exhaled breath

condensates. Accurately measuring the concentration of

glucose in exhaled breath may allow non-invasive

estimation of glucose concentration in blood, which in turn

could be used for routine monitoring of the blood glucose

concentration in diabetic patients. Currently, there is no

commercially available device to collect exhaled breath

condensate and measure its glucose level.

HO W IT WO RKS The glucose monitor consists of a

breath condensing unit that monitors the temperature,

volume, and glucose concentration of exhaled breath along

with a condenser for background air. The glucose

concentration of exhaled breath condensate is corrected

for the humidity and glucose concentration of background

air in order to deliver more reliable measurements

compared to those of similar technologies. The blood

glucose concentration is calculated from its correlation with

the corrected glucose concentration in the exhaled breath

condensate with fluorescent spectroscopy.

ADVANT AG ES The advantages of this technology are

that the sensor system does not require blood samples

while simultaneously reducing measurement complications

that may result from humidity and glucose in air.

SALIVA GLUCOSE METER

Glucose is present in saliva at low concentrations. The

device allows trace fluid samples from a biological surface to

be obtained for electrochemical analysis and the subsequent

detection of analytes. The device can be used to collect fluid

from the mouth and for such samples to be subsequently

processed to detect glucose, a metabolic product in saliva,

using disposable biosensor strips.

HO W IT WO RKS The device has a collections chamber

containing an absorbent hydrogel material with a connected

microfluidic channel. A sensing chamber is connected to the

channel that allows saliva samples to be extracted. The

sensing chamber contains an enzyme that detects the

glucose through electrochemistry. The glucose concentration

is calculated from the current generated in the biosensor

strip.

ADVANT AG ES The advantages of this technology are

that the sensor is quick, easy to use, does not require blood

samples and operates in a similar way to the current FDA-

approved blood glucose strips. The technique is very

sensitive and only needs very small saliva samples. The

strips can be manufactured in high volumes at low cost using

screen-printed thick films.Available for Immediate License

Only from Tekcapital®

.

For additional information contact:

Dr. Michael Kayat

Vice President

[email protected]

+1 305 200 3450 x 303 (office)

At the forefront of discovery

INNOVATION FOR SAFE, ACCURATE

AND PAINLESS DIABETES

MANAGEMENT

BREATH GLUCOSE MONITOR

Glucose is a non-volatile molecule found in exhaled breath

condensates. Accurately measuring the concentration of

glucose in exhaled breath may allow non-invasive

estimation of glucose concentration in blood, which in turn

could be used for routine monitoring of the blood glucose

concentration in diabetic patients. Currently, there is no

commercially available device to collect exhaled breath

condensate and measure its glucose level.

HO W IT WO RKS The glucose monitor consists of a

breath condensing unit that monitors the temperature,

volume, and glucose concentration of exhaled breath along

with a condenser for background air. The glucose

concentration of exhaled breath condensate is corrected

for the humidity and glucose concentration of background

air in order to deliver more reliable measurements

compared to those of similar technologies. The blood

glucose concentration is calculated from its correlation with

the corrected glucose concentration in the exhaled breath

condensate with fluorescent spectroscopy.

ADVANT AG ES The advantages of this technology are

that the sensor system does not require blood samples

while simultaneously reducing measurement complications

that may result from humidity and glucose in air.

SALIVA GLUCOSE METER

Glucose is present in saliva at low concentrations. The

device allows trace fluid samples from a biological surface to

be obtained for electrochemical analysis and the subsequent

detection of analytes. The device can be used to collect fluid

from the mouth and for such samples to be subsequently

processed to detect glucose, a metabolic product in saliva,

using disposable biosensor strips.

HO W IT WO RKS The device has a collections chamber

containing an absorbent hydrogel material with a connected

microfluidic channel. A sensing chamber is connected to the

channel that allows saliva samples to be extracted. The

sensing chamber contains an enzyme that detects the

glucose through electrochemistry. The glucose concentration

is calculated from the current generated in the biosensor

strip.

ADVANT AG ES The advantages of this technology are

that the sensor is quick, easy to use, does not require blood

samples and operates in a similar way to the current FDA-

approved blood glucose strips. The technique is very

sensitive and only needs very small saliva samples. The

strips can be manufactured in high volumes at low cost using

screen-printed thick films.

. For additional information contact:Non-Invasive Glucose Tek Limited Amy [email protected]+1 305 200 3450

NEW INNOVATIONS FOR SAFE, ACCURATE AND

PAINLESS DIABETES MANAGEMENT

BREATH GLUCOSE MONITOR

Glucose is a non-volatile molecule found in exhaled breath condensates. Accurately

measuring the concentration of glucose in exhaled breath may allow non-

invasive estimation of glucose concentration in blood, which in turn could be used

for routine monitoring of the blood glucose concentration in diabetic patients.

Currently, there is no commercially available device to collect exhaled breath

condensate and measure its glucose level.

HOW I T WO RKS The glucose monitor consists of a breath condensing unit that

monitors the temperature, volume, and glucose concentration of exhaled breath

along with a condenser for background air. The glucose concentration of

exhaled breath condensate is corrected for the humidity and glucose concentration

of background air in order to deliver more reliable measurements compared

to those of similar technologies. The blood glucose concentration is calculated

from its correlation with the corrected glucose concentration in the exhaled breath

condensate with fluorescent spectroscopy.

AD V AN T AG E S The advantages of this technology are that the sensor system

does not require blood samples while simultaneously reducing measurement

complications that may result from humidity and glucose in air.

Page 4: discoverytekcapital.com/wp-content/uploads/2017/07/Non-Invasive-Glucose-T… · BREATH GLUCOSE MONITOR Glucose is a non-volatile molecule found in exhaled breath condensates. Accurately

Available for Immediate License

Only from Tekcapital®

.

For additional information contact:

Dr. Michael Kayat

Vice President

[email protected]

+1 305 200 3450 x 303 (office)

At the forefront of discovery

INNOVATION FOR SAFE, ACCURATE

AND PAINLESS DIABETES

MANAGEMENT

BREATH GLUCOSE MONITOR

Glucose is a non-volatile molecule found in exhaled breath

condensates. Accurately measuring the concentration of

glucose in exhaled breath may allow non-invasive

estimation of glucose concentration in blood, which in turn

could be used for routine monitoring of the blood glucose

concentration in diabetic patients. Currently, there is no

commercially available device to collect exhaled breath

condensate and measure its glucose level.

HO W IT WO RKS The glucose monitor consists of a

breath condensing unit that monitors the temperature,

volume, and glucose concentration of exhaled breath along

with a condenser for background air. The glucose

concentration of exhaled breath condensate is corrected

for the humidity and glucose concentration of background

air in order to deliver more reliable measurements

compared to those of similar technologies. The blood

glucose concentration is calculated from its correlation with

the corrected glucose concentration in the exhaled breath

condensate with fluorescent spectroscopy.

ADVANT AG ES The advantages of this technology are

that the sensor system does not require blood samples

while simultaneously reducing measurement complications

that may result from humidity and glucose in air.

SALIVA GLUCOSE METER

Glucose is present in saliva at low concentrations. The

device allows trace fluid samples from a biological surface to

be obtained for electrochemical analysis and the subsequent

detection of analytes. The device can be used to collect fluid

from the mouth and for such samples to be subsequently

processed to detect glucose, a metabolic product in saliva,

using disposable biosensor strips.

HO W IT WO RKS The device has a collections chamber

containing an absorbent hydrogel material with a connected

microfluidic channel. A sensing chamber is connected to the

channel that allows saliva samples to be extracted. The

sensing chamber contains an enzyme that detects the

glucose through electrochemistry. The glucose concentration

is calculated from the current generated in the biosensor

strip.

ADVANT AG ES The advantages of this technology are

that the sensor is quick, easy to use, does not require blood

samples and operates in a similar way to the current FDA-

approved blood glucose strips. The technique is very

sensitive and only needs very small saliva samples. The

strips can be manufactured in high volumes at low cost using

screen-printed thick films.Tekcapital plc Oxford Center for Innovation New Road, Oxford, OX1 1BY United Kingdom Tel: +44 (0) 1865 261445 [email protected] www.tekcapital.com

WORKING WITH LEADING UNIVERSITY SCIENTISTS TO SELECT & COMMERCIALZE

DISRUPTIVE TECHNOLOGIES

Tekcapital plc - The World’s Largest University Network for Open Innovation

Tekcapital's objective is to create value from investing in new, university-developed intellectual properties (IP). With its proprietary discovery search engine, linked to 4,500+ universities in 160 countries, coupled with expert scientific review, Tekcapital makes it easy to find and acquire the new IP needed to create a competitive advantage. Our IP services include invention discovery reports, search tools, analytics and IP professional recruitment to help universities and companies create value from new discoveries. Tekcapital plc is quoted on the AIM market of the London

Stock Exchange (AIM: symbol TEK) and is headquartered in Oxford, in the UK.

For more information, please visit www.tekcapital.com.

© Tekcapital plc 2017 . All rights reserved.

Non-Invasive Glucose Tek Limited is a portfolio company of Tekcapital plc