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MaksimiljanKADIVEC Kristijana HERTL, Mateja KRAJC, Katja JARM, Anže DROLC IAEA, Vienna MAY 2015 BREAST CANCER SCREENING IN SLOVENIA

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Page 1: BREAST CANCER SCREENING IN SLOVENIAnucleus.iaea.org/HHW/Radiology/Clinical_Applications/...1.021.893 women, of them 262.400 aged 50 - 69 incidence: 2/1.000 1128 BC (2009) 434 died

MaksimiljanKADIVEC Kristijana HERTL, Mateja KRAJC,

Katja JARM, Anže DROLC

IAEA, Vienna

MAY 2015

BREAST CANCER SCREENING

IN SLOVENIA

Page 2: BREAST CANCER SCREENING IN SLOVENIAnucleus.iaea.org/HHW/Radiology/Clinical_Applications/...1.021.893 women, of them 262.400 aged 50 - 69 incidence: 2/1.000 1128 BC (2009) 434 died

SLOVENIA

2.003.358 inhabitants

1.021.893 women, of them

262.400 aged 50 - 69

incidence: 2/1.000

1128 BC (2009)

434 died (2009)

Page 3: BREAST CANCER SCREENING IN SLOVENIAnucleus.iaea.org/HHW/Radiology/Clinical_Applications/...1.021.893 women, of them 262.400 aged 50 - 69 incidence: 2/1.000 1128 BC (2009) 434 died

Institute of Oncology

Ljubljana

Zaloška 2, 1000 Ljubljana

Slovenia

[email protected]

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Breast cancer is important problem of the public health

1128

434

Vir: SLORA

Page 5: BREAST CANCER SCREENING IN SLOVENIAnucleus.iaea.org/HHW/Radiology/Clinical_Applications/...1.021.893 women, of them 262.400 aged 50 - 69 incidence: 2/1.000 1128 BC (2009) 434 died

START

21. april 2008 (invitations in march – 3 week in advance)

Page 6: BREAST CANCER SCREENING IN SLOVENIAnucleus.iaea.org/HHW/Radiology/Clinical_Applications/...1.021.893 women, of them 262.400 aged 50 - 69 incidence: 2/1.000 1128 BC (2009) 434 died

GOAL:

LOWER THE MORTALITY RATE FOR

25 – 30 %

to discover cancers under 10 mm

Page 7: BREAST CANCER SCREENING IN SLOVENIAnucleus.iaea.org/HHW/Radiology/Clinical_Applications/...1.021.893 women, of them 262.400 aged 50 - 69 incidence: 2/1.000 1128 BC (2009) 434 died
Page 8: BREAST CANCER SCREENING IN SLOVENIAnucleus.iaea.org/HHW/Radiology/Clinical_Applications/...1.021.893 women, of them 262.400 aged 50 - 69 incidence: 2/1.000 1128 BC (2009) 434 died
Page 9: BREAST CANCER SCREENING IN SLOVENIAnucleus.iaea.org/HHW/Radiology/Clinical_Applications/...1.021.893 women, of them 262.400 aged 50 - 69 incidence: 2/1.000 1128 BC (2009) 434 died

European guidelines for

quality assurance in

breast cancer screening and diagnosis

(fourth edition)

Page 10: BREAST CANCER SCREENING IN SLOVENIAnucleus.iaea.org/HHW/Radiology/Clinical_Applications/...1.021.893 women, of them 262.400 aged 50 - 69 incidence: 2/1.000 1128 BC (2009) 434 died

Dr. Lawrence von Karsa (Lyon, France)

EBCN (European Breast Cancer Network) Coordination

Office

IARC (International Agency for Research on Cancer)

Dr. Margrit Reichel (Wiesbaden, Germany)

Leading radiologist for pilot screening breast cancer

program in Germany

Prof. Dr. Peter Dean (Turku, Finland) – Head of the breast

screening program in Finland

Prof. Dr. Peer Scane (Oslo, Norway) – Head of the

srceening reference center in Oslo

Page 11: BREAST CANCER SCREENING IN SLOVENIAnucleus.iaea.org/HHW/Radiology/Clinical_Applications/...1.021.893 women, of them 262.400 aged 50 - 69 incidence: 2/1.000 1128 BC (2009) 434 died

ORGANISATION of BREAST CANCER SCREENING

IN SLOVENIA - 2007

• age 50-69, invitation every 2 years

• centralisation of the screening

• only digital equipment

• appropriate education and training of

all personnel involved in the screening procedure

• double reading

(reader should read 5000 MM per year, lead radiologist 10000 MM per year,

first 3000 MM under control of lead radiologist)

Page 12: BREAST CANCER SCREENING IN SLOVENIAnucleus.iaea.org/HHW/Radiology/Clinical_Applications/...1.021.893 women, of them 262.400 aged 50 - 69 incidence: 2/1.000 1128 BC (2009) 434 died

ORGANISATION of BREAST CANCER SCREENING

IN SLOVENIA - 2007

• conferences: consensus, preop. , postop.

• daily, weekly quality control of mammography machines

• no clinical examination

• setting of an adequate information system

• analysing performance indikator

Page 13: BREAST CANCER SCREENING IN SLOVENIAnucleus.iaea.org/HHW/Radiology/Clinical_Applications/...1.021.893 women, of them 262.400 aged 50 - 69 incidence: 2/1.000 1128 BC (2009) 434 died

Σ = 64.683

16.056

I.

II.

III.

Target population (50-69): 262.400

Average cumulative incidence rate

1998–2002

4,68-5,37

5,38-6,06

6,06-6,74

6,75-7,42

7,43-8,11

5.954

162 000

100 000

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ADVANTAGES

• Professionalism of the staff: kindness, discretion

and mainly humanity

• accuracy

• friendly environment

• good marked way to the screening place

• speed of the report, assessment, operation

• addditional education of staff

• quality of the equipment

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EDUCATION

BREAST CANCER SCREENING IN SLOVENIA

RADIOLOGISTS

Course for Lead radiologist and Readers 2 days

Course for US + biopsy (only Lead radiologist) 2 days

Lead radiologist - practice (reference center) 1 month

Readers – practice (reference center) 1 week

RADIOGRAPHERS

Positioning course 2 days

Practice (reference center) 14 days

ALL (radiologist, radiographer, surgeon, patologist, administrator, nurse)

MDC – Multidisciplinary Course (2 days)

Refreshment course every 2 years for radiographers and radiologists

WE ADD for all: 2 days course of communication skills !!!

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MEDICAL PHYSIST

• on line every day

• mammograph every 6 months

• controle of the diagnostic monitors (5MP)

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PGMI

•P (Perfect)

•G (Good)

•M (Moderately good)

•I (Inadequate)

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

1 3 5 7 9 11 13 15 17 19 21 23

DORA radiographers

statistics sept 2013 – march 2014

I

M

P+G

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Dora Information System

• Process based

• Task lists for all profiles:

radiologist, surgeons, pathologist,

administration

• Clinical data is stored

in openEHR archetypes and

templates

• Seamless integration with RIS

• Ware house

EHR Platform is used in Moscow City's EHR project.

electronic file of the women

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Modules

• Central registry

• Call center

• Mammographies

• Double blind screening

• Consensus

• Assessment

• Integration module

• eCRP

Radiologist result form

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invitations

map

Mobile unit

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TIMETABLE

M T T T M M W T W W T F F F

Double reading

CONSENSUS

Invitation for assessment - 4,5%

ASSESSMENT

Discussion with patients

10%

1,8% needle biopsy

M T T

PRE AND POSTOPERATIVE

CONFERENCE

10 - 15 days

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consensus conference

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pre and post operative conference

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SCREENING

TEAM

EPIDEMIOLOGIST

PATHOLOGIST

SURGEON

IT

RADIOLOGIST

RADIOGRAPHER

SEKRETARY BREAST NURSE

PHISIST

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Performance indicator

Programme DORA EU acceptable EU desirable

value level level

Proportion of women invited that attend for

screening 72.1% > 70% > 75%

Coverage of eligible women 31.8% / /

Proportion of women recalled for further

assessment

Initial screening

examinations 4.5% < 7% < 5%

Subsequent screening

examinations 2.3% < 5% < 3%

Breast cancer detection rate per 1000

screened

Initial screening

examinations 7.6/1000 7.5/1000 > 7.5/1000

Subsequent screening

examinations 4.1/1000 3.7/1000 > 3.7/1000

Performance indicators in Slovenian breast cancer screening programme

Dora, 21.4.2008 – 31.12.2012.

Proportion of screen - detected cancers

that are stage II+

Initial screening

examinations 35.5% -- < 30%

Subsequent screening

examinations 24.4% 25% < 25%

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Proportion of invasive screen - detected

cancers that are <= 10 mm in size

Initial screening

examinations 33.7% / >= 25%

Subsequent screening

examinations 26.5% >= 25% >= 30%

Interval cancer rate as a proportion of the

underlying, expected, breast cancer

incidence rate in the absence of screening

Within the first year (0-

11 months) 20% 30% < 30%

Within the second year

(12-23 months) 48% 50% < 50%

Time (in working days) between result of

screening mammography and offered

assessment 3.6 working days 5 wd 3 wd

Updated on 17.3.2014

Performance indicators in Slovenian breast cancer screening programme Dora,

21.4.2008 – 31.12.2012.

Programme DORA EU acceptable EU desirable

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THANK YOU