bovine pregnancy associated biomolecules

7/23/2019 BOVINE PREGNANCY ASSOCIATED BIOMOLECULES

1/28

"o& Egt`kg H

]TGAJHJOV H__@OFH^GNDF@K@LGOWLG_

Egt`kg H,_I _fjab # _I Hahtqhl


2/28

"o& Egt`kg H

]TGAJHJOV

KH^GTJHL_V_^GK

"_}gjogt g~ hl*,4==>&

O@JOG]^W_


3/28

"o& Egt`kg H

FCJ+

G]C

G_

]HA

OA

"Hsobbgfk # U`jngi,86419Ih}}gs g~ hl*,866=9 Dht~`l g~hl*,86279 K`t~`j g~ hl*, 86219 U`lf g~ hl*,86689 Bgjngts`j

g~ hl*, 866?&

O@JOG]^W_

]L


4/28

"o& Egt`kg H

^bgsg sfajhls+htg }`~gj~fhl khtigts `c

}tgajhjov hjn gkdtv`jfo fhdflf~v hs ~bgvfjclwgjog }tgajhjov tgo`ajf~f`j hjn swoogsscwl

fk}lhj~h~f`j*

O`jog}~ws ngtfgn swds~hjogs htg o`jsfngtgn ~`dg k`tg }tgofsg hjn tglfhdlg khtigts `c

}tgajhjov hjn cg~hl qgll dgfja*

O`jog}~ws sgotg~gs s}gofcfo swds~hjogs c`t f~stgo`ajf~f`j dv k`~bgt*

"_`wsh g~ hl*,4==39_uhcthjsih g~ hl*,4==3&


5/28

"o& Egt`kg H

_gotg~`tv }t`nwo~ `c ~bg o`jog}~ws, ct`k nhv

8= ~` 4> `c ags~h~f`j # }ghis h~ nhv 81 fj oh~~lghjn nhv 83 fj sbgg}*

"Dht~`l g~ hl*,86279 T`dgt~s g~ hl*,4==1&

]tggj~s lw~g`lvsfs dv sw}}tgssfja ]AC4sgotg~f`j*

]tggj~s tgowttgjog `c gs~tws hjn gjswtgs

}tgajhjov ~` o`j~fjwg*

W}+tgawlh~gs gr}tgssf`j `c j`* `c }t`~gfjs hjnagjgs*

]t`fng swf~hdlg gjft`jkgj~ l`ohllv ~` ~bg

o`jog}~ws*

FJ^GTCGT@J


6/28

"o& Egt`kg H

]`ssgssfja h k`lgowlht qgfab~ `c 4=+4> iNhqf~b 814 hkfj` hofns # o`jsfngtgn hs }tfkg

sfajhl c`t KT]*

Tgkhfjs qf~bfj ~bg w~gtfjg lwkgj hjn n`gsj`~ h}}ght fj kghswthdlg xwhj~f~fgs fj

kh~gtjhl dl``n `t `~bgt d`nv clwfns*

^bgtgc`tg, ohj j`~ dg wsgn hs h khtigt c`t

G]N*

O`j~f

"Ijfoigtd`oigts g~ hl*,8623&


7/28

"o& Egt`kg H

Ghtlfgs~ ij`qj sfajhl olhfkgn ~` dg s}gofcfo c`t

cgt~flfuh~f`j*Cfts~ ngsotfdgn fj kfog hjn lh~gt `j ~` sbgg},oh~~lghjn bwkhjs*

"K`t~hj g~ hl*,861>9Jhjohtt`q g~ hl*,8628&

Obhtho~gtfugn hs alvo`}t`~gfj `t }`lv}g}~fng qf~b h}`~gj~ fkkwj`sw}}tgssfg }t`}gt~fgs*"J``jhj g~ hl*,8616&

Ng~go~gn dv T`sg~~g fjbfdf~f`j ~gs~*"K`t~`j g~ hl*,862>&

_gtwk TF^ hlwgs l`q `j ~bg nhv `c HF, fjotghsgn `jnhv ? hjn tgkhfjgn bfab wj~fl gkdtv` tgo`gtv `j nhv1 hjn swdsgxwgj~lv ngotghsgn ~` h l`qgt lggl dv hqggi hc~gt gkdtv` tgo`gtv*

"_hi`jew g~ hl*,866?&

GHTLV]TGAJHJOVCHO^@T


8/28

"o& Egt`kg H

TF^ hsshv fs nfccfowl~, ~gnf`ws,

owkdgts`kg hjn ~fkg o`jswkfja ~gs~*Fjnftgo~ ~gs~, swds~hjogs ~bh~ bhgsfkflht gccgo~s khv o`jc`wjn ~bg tgswl~s*^bgtgc`tg, f~ o`wln j`~ dgo`kg }`}wlht

~gs~ c`t t`w~fjg }tgajhjov nfhaj`sfs fjchtk hjfkhls*H~~gk}~ ~` fs`lh~g h }t`~gfj tgs}`jsfdlgc`t G]C ho~ff~v bhs }t`nwogn htfhdlg

tgswl~s qf~b`w~ hjv o`jfjofjafngj~fcfoh~f`j `t obhtho~gtfuh~f`j*"Kgb~h g~ hl*, 86269 Ilfkh g~ hl*, 86649^btglchll, 866>&

O`j~f


9/28

"o& Egt`kg H

Khjv nfhaj`s~fo if~s

IGK_ Df`^gs~ L~n* "Lf~~lg~`j, O@&,Ghtlv O`jog}~f`j Cho~`t "GOC& ~gs~"O`jog}~` Nfhaj`s~fos, Ij`rfllg, ^J&

# GOC nf}s~foi ~gs~

"Hnhks hjn E`tnhj, 86669 O`jog}~`Nfhaj`s~fos, 86669 Ngs o`~ghwr g~hl*,4===&

Ng~go~s }tgajhjov qf~bfj >2 bts hc~gt

o`jog}~f`j*K`tg chlsg+}`sf~fg # chlsg+jgah~fg tgswl~s*

_` GOC ~gs~ fj }tgsgj~ c`tk fs j`~ h tglfhdlgkg~b`n c`t ng~gtkfjfja ghtlv }tgajhjov*

O`tn`dh g~ hl* "4==8&

O`j~f


10/28

"o& Egt`kg H

Khe`t gs~t`agj sgotg~gn ct`k dfjwolgh~g oglls*

Gs~fkh~gn fj kfli, }lhskh hjn wtfjg*

"Bgjngts`j g~ hl*,866?&

Kghj o`jo* fj dwcchl` htfgs dg~qggj 8>*2 ~`

4?*3 ja/kl ct`k sgo`jn ~` jfj~b k`j~b `c}tgajhjov* "Bwja hjn ]thihsb,866=&

TFH/GFH qhs wsgn ~` ng~go~ gs~t`jg swl}bh~g*

"Bgjngts`j g~ hl*,866?9]thihsb # Khnhj,866?&Ng~go~s }tgajhjov h~ ?8/4+> k`j~bs `c

ags~h~f`j f*g* ~`` lh~g ~` dg o`jsfngtgn hs hj

ghtlv fjnfoh~`t `c }tgajhjov*

G_^T@JG_WL]BH^G


11/28

"o& Egt`kg H

Ob`tf`jfo A`jhn`~t`}fjs

Fj 8641, Hsobbgfk hjn U`jngi cfts~ tg}`t~gn ~bg}tgsgjog `c h a`jhn`~t`}fo cho~`t fj ~bg wtfjg `c}tgajhj~ q`kgj*

Ij`qj hs bwkhj ob`tf`jfo a`jhn`~t`}fj "bOA&,alvo`}t`~gfj sgotg~gn dv ~bg ~t`}b`dlhs~*

Dhsgn `j ~bfs, hj hoowth~g kg~b`n `c G]N fj bwkhj qhs

nggl`}gn*

bOA fs cfts~ ng~go~hdlg 2 ~` 88 nhvs hc~gt o`jog}~f`j*

Fj 86?=, O`lg hjn Bht~ ngk`js~th~gn ]K_A, j`qij`qj hs gxwfjg ob`tf`jfo a`jhn`~t`}fj "gOA& }t`nwogn

ct`k ~bg gjn`kg~tfhl ow}s o`k}`sgn `c ~t`}b`dlhs~fooglls*

Ng~go~hdlg ct`k nhv ?7+>= nhvs `c }tgajhjov*

_wob swds~hjog n`gs j`~ grfs~ fj twkfjhj~s, ohjj`~ dg

wsgn hs fjnfoh~`t c`t G]N*


12/28

"o& Egt`kg H

_vj~bgsfugn dv ~bg dfjwolgh~g oglls # sgotg~gn~bt`wab`w~ ags~h~f`j*

"Ih}}gs g~ hl*, 866=&KQ d`fjg+ ?4+?>, `fjg+ 44 # oh}tfjg+ 4? iNh,

"Dvh~~ g~ hl*, 8623&Khkk`agjgsfs, tgawlh~f`j `c cg~hl at`q~b, `htfhj

s~gt`fn`agjgsfs # kh~gtjhl fj~gt+kgnfhtv kg~hd`lfsk*"Dvh~~ g~ hl*, 8664&

O`jogj~th~f`j tgkhfjs l`q # htfgs ct`k 8 ~` 4 ja/kl ~bt`wab`w~ ags~h~f`j*

"Dgoigts g~ hl*, 8624, Dvh~~ g~ hl*,8621&_fjog f~ fs ng~go~gn `jlv ct`k ?+> k`j~b `c ags~h~f`jfj oh~~lg,f~ fs j`~ wsgn hs hj fjnfoh~`t `c ghtlv}tgajhjov*

"Dvh~~, 8621&

]LHOGJ^HLLHO^@AGJ


13/28

"o& Egt`kg H

]TGAJHJOV

H__@OFH^GNALVO@]T@^GFJ_


14/28

"o& Egt`kg H

]TGAJHJOVH__@OFH^GNALVO@]T@^GFJ_

Hofnfo Alvo`}t`~gfjs dgl`jafja ~` Hs}ht~fo]t`~gfjhsg chkflv*

K`lgowlht s~two~wtg bhs k`tg ~bhj 7= ' HH

sgxwgjog fngj~f~v qf~b ]g}sfj, Oh~bg}sfj N # G*

_gotg~gn dv dfjwolgh~g ~t`}b`dlhs~fo oglls `c

}lhogj~h*

O`js~f~w~g h at`w} `c }tgajhjovs}gofcfo }t`~gfjs*

Jghtlv 44 nfccgtgj~ ]HAs fj twkfjhj~s bhs dggjfngj~fcfgn h~ nfccgtgj~ s~hag `c ags~h~f`j*

"Rfg g~ hl*,8668,866>&

"Rfg g~ hl*,8668,866>,86619Atggj g~ hl*, 4===9 Ahtdhv` g~ hl*,4==7&


15/28

"o& Egt`kg H

]HA8

^bg cfts~ kgkdgt `c ~bg chkflv qhs fs`lh~gn dv Dw~lgtg~ hl* "8624& ct`k d`fjg }lhogj~h hjn qhs jhkgn hs}tgajhjov s}gofcfo }t`~gfj D "]_]D&*

_wdsgxwgj~lv, tglh~gn }t`~gfjs bhg dggj fngj~fcfgn qf~b

~bg nfccgtgj~ jhkgs swob hs ]HA8 "Rfg g~ hl*, 86689U`lf g~ hl*, 8668&, ]_]+3= "Kfhl`j g~ hl*, 866?&, _DW?"H~ifjs`j g~ hl*, 866?& fj twkfjhj~ wjawlh~gs*

^bgsg }t`~gfjs htg ng~go~hdlg fj kh~gtjhl dl``n hjnqgtg tg}`t~gn ~` dg wsgcwl hs }tgjh~hl khtigts c`t}tgajhjov nfhaj`sfs hjn gkdtv`jfo fhdflf~v fj htf`wsn`kgs~fo hjn qfln twkfjhj~s*

"_hssgt g~ hl*,86239 U`lf g~ hl*,86649Kfhl`j g~ hl*, 866?9]gtgjvfg~ hl*, 4==49 _ugjof g~ hl*, 4==?9 Hvhn g~ hl*, 4==1, ]hjhsfgqfou

g~ hl*, 4==1&


16/28

"o& Egt`kg H

KQ thjags+ ?1+12 iNh*

K`tg`gt, ]HA bhg hls` t`lgs fj}lhogj~`agjgsfs, ng~go~f`j `c ~qfjs, sgr `c~bg c`g~ws*

"Dw~lgt g~ hl*,86249 _hssgt g~ hl*, 86269 U`lf g~ hl*, 8668&

O`j~f

"]h~gl g~ hl*,8667,86619 Shsxwgs g~ hl*, 86679 Qfllhtn g~hl*, 86679Atggj g~ hl*, 4==79 L`}gu+Ah~fws g~ hl*, 4==1&

O`j~f


17/28

"o& Egt`kg H

^bg ]HA agjg qhs cfts~ ol`jgn fj oh~~lg #

_bgg} "Rfg g~ hl*,8668&Lh~gt `j fj khjv s}gofgs+

a`h~ "Ahtdhv` g~ hl*,4===&,

}fa "_uhcthjsih g~ hl*,8667&

# `~bgt s}gofgs "Rfg g~ hl*,8661&*

oNJH kfot`htthv hjhlvsfs ngk`js~th~gn

gr}tgssf`j `c sggthl ]HA k`lgowlgs ghtlv hs

nhv 1 ~` 8> `c }tgajhjov `t ggj ghtlfgt fj

oh~~lg "Wsbfuhqh g~ hl*,4==>&*

]HA agjg


18/28

"o& Egt`kg H

Cfts~ agjg ~` dg ol`jgn fj oh~~lg*

6 GR@J_ "66+ 428 d}&

2 FJ^T@J_ "21+82== d}&

]HA 8AGJG"OH^^LG&

HOO* J@ aNJH_GX*"d}&

FNGJ^FCFGNDV

L412?? Gr`js 8+3 Rfg g~ hl*,

8667L442?> Gr`j 1+2L412?4 Gr`j 6

L412?? 843=

"]t`k`~gt&

Agj+DhjiNH^H

"Rfg g~ hl*,8667&


19/28

"o& Egt`kg H

]HA 8 AGJG ]T@CFLG FJ SHTF@W_ _]GOFG_

_]GOFG_ FNGJ^FCFGNDV

kTJH"d}&

OH^^LG Rfg g~ hl*,8668 8467

_BGG] +n`+ 8433A@H^ Ahtdhv` g~

hl*,4===88>?

]FA ]hjhsfgqfou,4==>

8?7?


20/28

"o& Egt`kg H

Tgo`kdfjhj~ }t`~gfj ~gobj`l`av bhs}t`fngn

hgjwg c`t ~bg agjgth~f`j `c swccfofgj~

hk`wj~ `c s}gofcfo }t`~gfjs `c fj~gtgs~ct`k h sfjalg agjg,

wsgn c`t ~bg nggl`}kgj~ `c fk}t`gnnfhaj`s~fos c`t ghtlv }tgajhjov nfhaj`sfs

# o`jog}~ws fhdflf~v*"]h~gl g~ hl*,4==>&

O`j~f


21/28

"o& Egt`kg H

]HAs gr}tgssf`j }t`cflg

OGLL_ ]HA }t`cflg

DFJWOLGH^G OGLL_ 8,?,>,7,3,1,6

K@J@+ #DFJWOLGH^G OGLL_

4,2,8=,8?

"Atggj g~ hl*,4===9 Wsbfuhqh g~ hl*,4==>&

Nhvs ]HA }t`cflg

1 >,7,3

1 ~` 8> 88,83,818> ~` 48 8,7+1,6+8?,87+81,86,48


22/28

"o& Egt`kg H

]HA 8

K`lgowlht qgfab~ + 31 iNh

Shtf`ws fs`c`tks "]F5>*>, >*3, 7*4 # 7*>&

Hkfj` hofns +?2=D`fjg hjn `fjg ]HA8 sb`qs 1?' hhfngj~f~v

]t`~g`lv~fohllv fjho~fgDgl`ja ~` d`]HA8 at`w}

"Rfg g~ hl*,86689 U`lf g~ hl*,86689Awtw}thshn g~ hl*,86639&

O ~f


23/28

"o& Egt`kg H

Bhlc+lfcg fs h}}t`rfkh~glv 1+6 nhvs*

Dgo`kgs ng~go~hdlg s``j* Hc~gt fk}lhj~h~f`j fs

fjf~fh~gn*

Ng~go~gn dv TFH hjn GLF_H

"U`lf g~ hl*,86649 ]gtgjvf g~

hl*,4==49Atggj g~ hl*,4==7&

O`j~f***

"Ifthi`cg g~ hl*,866?&


24/28

"o& Egt`kg H

]HA 8 ]T@^GFJ ]T@CFLG FJ SHTF@W_ _]GOFG_

_]GOFG_ K@L*Q^

"iNh&

HKFJ@HOFN_

}B

OH^^LG ?1+12 ?2= >*=+>*>

_BGG] >1+6= ?24 >*=+3*2

A@H^ 77,76,34 ?>8 >*6+3*4

B@T_G ?1,>8 ?22 >*7

UGDTH + ?22 +

NGGT ?=,7=,77 ?2= +]FA >? ?26 7*3+3*4

"_uhcthjsih g~ hl*,4==3&


25/28

"o& Egt`kg H

TFH >61 "]WTFCFGN& "U`lf g~ hl*,8664&

Nfhaj`sg }tgajhjov + 6?'

# j`j+}tgajhj~ + 61'@gthll hoowthov + 6>'

TFH 1=3 # 1=2 "_]& "]gtgjvf g~ hl*,4==4&

GLF_H _V_^GK "_]& "Atggj g~ hl*,4==7&

NFHAJ@_^FO_ NGSGL@]GNW_FJA ]HA 8 ]T@^GFJ "OH^^LG&

IF^ NGSGL@]GN CT@K ]HA 8+ Df`]TVJ

"_hssgt,4==3&


26/28

"o& Egt`kg H

]HA8 o`jogj~th~f`j "ja/kl& fj dl``n `c oh~~lg

Hdlg ~` ng~go~ ]HA k`lgowlgs fj ~bg kh~gtjhl dl``nhs ghtlv hs 48 nhvs }`s~ HF

O`k}htgn ~btgg gs~hdlfsbgn TFH"]gtgjvf g~ hl*,4==4&

Nhvshc~gt HF

TFH F TFH FF TFH FFF

48 =*>? =*>2 =*3>

?4 4*>? >*81 >*?=

>4 >*=8 7*3= 7*73


27/28

"o& Egt`kg H

]HA 8 ]T@^GFJ ]T@CFLG FJ SHTF@W_ _]GOFG_

_]GOFG_ K@L*Q^

"iNh&

HKFJ@HOFN_

}B

OH^^LG ?1+12 ?2= >*=+>*>

_BGG] >1+6= ?24 >*=+3*2

A@H^ 77,76,34 ?>8 >*6+3*4

B@T_G ?1,>8 ?22 >*7

UGDTH + ?22 +

NGGT ?=,7=,77 ?2= +]FA >? ?26 7*3+3*4

"_uhcthjsih g~ hl*,4==3&


28/28

"o& Egt`kg H

^BHJI V@W

bovine pregnancy associated biomolecules

Documents