Boston University

Kenneth LutchenProfessor and Chair

Workshop on BME Teaching of

Innovation, Design & Entrepreneurship

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The BU-BME The BU-BME Senior Project ProgramSenior Project Program

Course 1Course 1: How to Approach, Perform, Manage and CommunicateCommunicate Independent Technical Projects, most in RealisticRealistic “Team”.

Course 2Course 2: Introduce Students to Best Practices in Design, Development, Marketing and Entrepreneurship in BME Industry

Engages all Full-time Faculty, Industrial Advisory Board, School Management, and use of Outside Hospitals, Laboratories, Companies as additional project mentors.

Faculty Provide Technical Guidance and Mentoring Builds Repertoire of Technical Communication Skills

– how skills complement scientific progress and discoveryhow skills complement scientific progress and discovery Detailed Technical/Scientific (Individual) Accountability is Enforced

through “ContinuousContinuous” Technical Communication Holy Grail of Accountability is Final Conference

– subliminal competition among students (and faculty)

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Course 1: Biomedical Engineering Senior Projects.

Semester I (2 credits)Semester I (2 credits)– Introduction– Approach to

Independent Research– Proposal Writing– Statistical Analysis– Oral Presentation

Techniques (proposal)» By good & bad example

Semester II (4 creditsSemester II (4 credits)– Progress Report Writing– Scientific Ethics– Abstract Writing– Final Report Writing– Oral Presentation

Techniques (final report)

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Course 2: Design, Development, Marketing, and

Entrepreneurship in Biomedical Engineering Transition from Engineer to Product DeveloperTransition from Engineer to Product Developer

– Art Rosenthal, Chief Scientific Officer, Boston Scientific Co.Art Rosenthal, Chief Scientific Officer, Boston Scientific Co. Medical Device DevelopmentMedical Device Development

Art Coury, Vice President, Genzyme CorpArt Coury, Vice President, Genzyme Corp.. Marketing Driven Strategies and MarketingMarketing Driven Strategies and Marketing

– Peter Russo, Director Entrep. & Management Institute, BU SMGPeter Russo, Director Entrep. & Management Institute, BU SMG Intellectual Property and Innovation in BMEIntellectual Property and Innovation in BME

– Steve Girouard, Manager Heart Group, Guidant CorpSteve Girouard, Manager Heart Group, Guidant Corp.. Quality Control and Reliability in Hardware and Software Medical Quality Control and Reliability in Hardware and Software Medical

Device IndustryDevice Industry– David Jones, Director Quality Control, Phillips Medical SystemsDavid Jones, Director Quality Control, Phillips Medical Systems

Clinical Regulatory Issues in BMEClinical Regulatory Issues in BME– Robert Kung, Vice President, AbiomedRobert Kung, Vice President, Abiomed

Entrepreneurship in Biomedical EngineeringEntrepreneurship in Biomedical Engineering– Peter Russo, Director Entrep. & Management Institute, BU SMGPeter Russo, Director Entrep. & Management Institute, BU SMG– Panel: Case Studies (Three BME faculty with Start Up Companies)Panel: Case Studies (Three BME faculty with Start Up Companies)

Novel & Effective Methods:Innovation & Entrepreneurship

Proposals (must defend what is novel) Senior Conference (public presentation

motivates innovation) Lectures on process of innovations

– Deliverables (patent search and analysis)

Lectures on Entrepreneurship– Deliverable (mini-business plan)

Panel Discussion from Faculty with Concrete Experience in Innovation and Entrepreneurship

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How do you measure outcomes?

Editing Capabilities Proposals (Science-type Format) Progress Reports Outcomes Related to Product Design and Innovation:

– Recasting of Project in Terms of Functional vs. Performance Specifications

– Casting Project via a projected product and addressing Intellectual Property, Market Analysis, and Business Plan for Potential Product

Final Report

Final “Public” ConferenceFinal “Public” Conference

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Senior Project Senior Project ConferenceConference““The Capstone The Capstone within a Capstonewithin a Capstone””

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Formal Technical Formal Technical Conference: Oral OnlyConference: Oral Only

Attended by:Attended by: All BME FacultyAll BME Faculty All BME SeniorsAll BME Seniors Many UG & Grads & AlumniMany UG & Grads & Alumni Numerous BME Companies & Numerous BME Companies &

Laboratories (> 150 guests/yr)Laboratories (> 150 guests/yr)

18th Annual Biomedical Engineering18th Annual Biomedical EngineeringSenior Project ConferenceSenior Project Conference

7:50 Opening Remarks 8:00 Session 1: Cell and Tissue Engineering & Micro BioSystems 9:35 Break10:00 Session 2: Patient Monitoring, Bioinstrumentation & Biomedical Optics11:50 Lunch12:40 Session 3A: Genomic Engineering

Session 3B: Neuromuscular and Neurofeedback Enginereing 1:55 Break 2:05 Session 4: Auditory and Neuro Bioengineering 3:25 Break 3:45 Session 5: Biomedical Imaging & Cell-Tissue-Organ Biomechanics 5:35 Closing Remarks BOSTON

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Examples and Range of Topics for Senior Capstone Projects

Nanoporous Inorganic Biocapsules for Cellular Immunoisolation and Controlled Drug Delivery

Fabrication of Vascular Network In Vitro Optical Measurement of Drug Diffusion into Tissue Design and Implementation of a System for Real-Time Experimental

Control of Auditory Stimuli Using a Genetic Toggle Switch and Bacteriophage to Control Biofilm

Formation Use of Foot Pressure Related Feedback to Improve Balance Control Modeling Intracellular Signaling Pathways Perfusion MRI of Brain Tumors in a Mouse Model of Arterial Spin

Labeling Induction of a Joint Structure by Controlled Stimulation During Fracture

Healing Quantifying Lung Compliance in Acute Respiratory Distress via High

Resolution Computer Tomography

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