Body contouring

TIPS and HINTS

مفيش حاجة تخلي

ابني يخس؟؟

Outline • Weight lose medications and remedies:• Herbal remedies (facts and myths). • Novel pharmacological treatment of obesity.• Special populations (pregnancy, lactation, diabetes, CVSd)

• Body contouring medications and protocols:• Localized obesity.• Flabiness and stretch marks.• Cellulite.• Breast enlargement medications.

• Pediatric obesity

Adulterated products HAAD LIST

Adulteration with

SibutramineCardiovascular

events 12%Phencyclidine

NMDA RAntag Psychological dependence T3 and T4Mazindol

Amphetamine like

(sympathomimetic)

Phenolphthalein (laxative) Carcinogenic

Herbal remedies and weight loss

Herbal remediesLaxatives

and diureticsmeso-oral

Altered fat, carb

absorption Altered fat,

carb metabolism

Altered fat storage

Famous and effective herbal remedies

chemical classification

Caffeine

Garcinia cambogia (Hydroxycitric Acid)

HCA ↑lipid ox. ↓appetite

Chitosan

↓fat absorpt

ion

Green Tea

Hoodia

Appetite suppressant

Benincasa hispida (winter melon)

Appetite suppressant

SSRI

Catha edulis (Yemenian’s Esteba7a)

Amphetamine like agent

Capsicum annuum

Sympathomimetic

Cyamopsis tetragonolobus (Guar GUM) = Glactomannan

Reduce appetite by

delaying gastric emptying

Inhibition of nutrient absorption

Hibiscus sabdariffa

Alpha-amylase inhibitor (weak)

Phaseolus vulgaris

Alpaha-glucosidase inhibitor

Triticum aestivum (whole grains)

Alpha-amylase inhibitor

Panax ginseng

Anorexic Pancreatic

lipase inhibitor

Punica granatum (الرمان)

Pancreatic lipase

inhibitor

Novel Pharmacological

treatment

Lorcaserin

5-HT 2c agonist

3% in 12 wk, without diet or exerciseApproved for BMI > 30

Tesofensine

Noradrenaline, dopamine and 5-HT reuptake inhibitor

9% with higher dose (0.5mg) in 25 wks, with exer & diet

Zonisamide

Anticonvulsant -D2 agonist

MAO inhibitor (weak)

5% in 16 wks with exer and diet

Rimonabant(and taranabant)

inverse agonist for the

cannabinoid receptor CB1

Withdrawn (sever depression and suicidal) , illegal sales

Contrave (Bupropion + naltrexone)

NA/ D2 RI-> endorphin release (-ve feedback) so

add naltrexone

Empatic (Bupropion + Zonisamide)

Bup offset depression and sedation of zoni

and Zoni offset Bup induced results

Qsymia (phentermine + topiramate)

Low dose amphetamine + anti convulsant topiramate .