Blood TypeDecember 1, 2009

Catalyst Answer and turn in!!! (not open book!)

What are the four parts of blood?

Contents of Blood Plasma (55%) Erythrocyes Leukocytes Platelets

Aim What differentiates one blood type from

another?

Learning Target! I CAN explain what differentiates one blood

type from another

A-G-E-N-D-A- Catalyst Brainstorm Lesson Practice

BRAINSTORM! List as many blood types as you know!

Our list...

4 main types A B AB O

Brief History 1901 Karl Landsteiner Later won the Nobel Prize Developed the A-B-O System

Impact Led to successful blood transfusions Millions of lives have been saved

So, what makes A different from B different from O? Presence of an antigen on the surface of an

erythrocyte

Antigen- a substance, usually a protein, that stimulates the body to produce antibodies against it

If you are type A You have an A antigen on your erythrocytes

If you are type B You have a B antigen on your erythrocyes

If you’re type AB, you have both

If you’re type O, you have neither

Blood plasma has proteins called ANTIBODIES What do you know about antibodies?

Antibody A protein in the blood serum that destroys

or inactivates a specific antigen Have a specific shape

A antibodies react with A antigens B antibodies react with B antigens

Type A people have B antibodies

Type B people have A antibodies

Tybe AB people DON’T have antibodies

Type O people have BOTH antibodies

Pulse.check. If you have type A blood, what is your

antigen, what are your antibodies? Antigen = A Antibody = B

Pulse check. If you have type O blood, what are your

antigens and antibodies? Antigens – none Antibodies – A and B

ABO - prevalence in USBlood Type %

A 42

B 10

AB 4

O 44

When an antibody reacts with an antigen, agglutination occurs

Agglutination – the clumping together of red blood cells by the action of an antibody