518-10 Dogok 2-dong, Gangnam-gu Seoul

135-854 Korea

822-501-3939 Tel. 822-578-2716 fax

www.e-inbody.com

Biospace Overview

Message from CEO

InBody Technology

Customers List

Testimonial

Clinical Paper

Certificate

Reference Book

1996 Established Biospace Co., Ltd.

1999

BIA technology transfer to Yamato

Acquired CE0120, EN46001, MDD,

ISO9001, MHLW certificate

2000

Established Biospace Co., Ltd. in Japan

Listed on KOSDAQ

2002 Manufacturing facility constructed in Chun-an City

2003 Acquired FDA approval

2004 Launched Biospace Inc. in the USA

2006

Technology innovation enterprise awarded by Korea Institute of Science & Technology (KiSTEP)

High Technology Invention awarded by Korea Industrial Property office

Awarded Minister’s Prize of MOCIE (Ministry of Commerce, Industry & Energy)

at 36th Precision Technology Promotion (Precise product technology section)

Awarded Excellent Enterprise Prize at Korean Superior Medical Equipment

exhibition hosted by Korea Food & Drug Administration Home care InBody Release

2007 Certificate of INNO-BIZ awarded by Small and Medium Business Administration

Korean World-class Product Award2007 by Minister of Commerce, Industry and Energy

Biospace Overview

With the continuing increase in standard of living, the focus on quality of life has amplified in recent times. In particular, obesity is a health issue featured in the mass media that has been warranting more attention than ever before. More and more people are coming to realize that obesity is at the root of all habitual illnesses, and because of this correlation interest in obesity treatment is on the rise. Biospace’s body composition analyzer, InBody stands at the center of this anti-obesity movement. Up until recently, most people believed that obesity could be precluded by simple losing a certain number of kilograms in body weight. However, with the development of the InBody, Biospace has made the terms, “body weight. However, with the development of the InBody, Biospace has made the terms, “body composition” and “body fat,” popular, and has spread the knowledge that the prevention of obesity hinges on the reduction and control of body fat. Biospace’s trailblazing activities in this area are evident in the label of “InBody Test”, a commonly given body composition analysis that has recently increased in popularity. InBody made by Biospace, is the world’s first body composition analysis device that uses the 8-point tactile electrode method. Having received FDA approval in the United States and approval of other countries’ authorities, such as in Japan, this product’s high quality and accuracy has been validated. With the unparalleled performance of the InBody in the domestic obesity diagnosis market Biospace has solidified its foundation as a professional medical device manufacturer. The plan for the future entails the company’s ongoing development and expansion into a comprehensive professional health care organization. In particular, the company is striving to achieve superior competitiveness that will facilitate success in advanced markets around the world, such as those in the United States, Japan, and Europe.

Message from CEO

In recent years, people have come to recognize that obesity causes a wide range of health problems. Unfortunately, there are few ways for the smart detection of obesity. As the most effective and scientific way to identify obesity, body composition analysis at this time reminds us of the critical importance of novel technology. Over the past decades, technology has been developed analyzing body composition based on the difference in electrical conductive properties of various biological tissues. Bioelectrical Impedance Analysis (BIA) has many advantages over other methods in that it is safe, rapid and easy to perform, and requires little training for operators. Thus, this technology has become widely used in hospitals, health and fitness centers, and in field studies. Nevertheless, in detecting acute or chronic changes in body composition, the clinical usefulness of conventional BIA has been limited to healthy average people. Due to localized fluid accumulation or loss and inability to assess the distribution of water accurately between intracellular water (ICW) and extracellular water (ECW), there had been difficulties applying it to patients, the elderly, children and athletes. However, they are the very people who really need to know their body composition. Biospace has reinforced conventional BIA. These improvements were proved with lots of clinical research papers. Because the body is not an isotropic conductor with uniform cross-sectional areas, we consider the body as five cylinders; four limbs and the trunk. The amount of body water is measured segmentally. Multi-frequency technology makes it possible to measure ICW and ECW separately. Thus, there would be no needs of empirical estimation to compensate inaccuracy, avoiding insensitive measurement. FDA approval of the apparatus and the method along with many other international patents and certifications assures the above long effort of Biospace. Now Biospace, as a pioneer, is the outstanding company specialized only in body composition analyzers. We would like to supply our products in every clinic, hospital, fitness center and research institute around the world. Biospace is always ready for the international markets with various obesity management products for health care professionals. We will continue to each for innovative solutions to our products, to lead in corporate responsibility, to extend our legacy of doing business the right way for our customers and to leap into a global company. Thank for your interest in Biospace.

Ki-Chul Cha Ph.D Chief Executive Officer Biospace Co., Ltd.

Ki-Cul Cha Ph.D 1996 – CEO, Biospace Co., Ltd.

1992 – 1994 Post Doctor, Harvard Medical School

1986 – 1992 Ph D, Bioengineering, Utah Univ. USA

1982 – 1986 Research staff at Daerim Technical Research Center

1980 – 1982 MS, Mechanical Engineering, KAIST

1976 – 1980 BS, Mechanical Engineering, Yonsei Univ.

*

InBody Technology

1. Use of Multi-frequency Technology to Measure ICW and ECW separately

At Low Frequency AT High Frequency

The problem with conventional BIA at a single low frequency is that it has to estimate the amount of intracellular water from extracellular because a low frequency cannot pass through the plasma membrane and measure intracellular water. The bilayered cellular membrane divides the body cell into intracellular and extracellular water. The intra-and extracellular waters are proportionate in a healthy body; however, an imbalanced body fluid distribution occurs in those who are elderly or suffer from obesity, or geriatric diseases and they are the very people who need to analyze their body composition. Extracellular water is measured by low frequency currents (lower than 50 kHz), and intracellular water is measured by high frequency currents (higher than 200 kHz). Contemporary BIA equipment acknowledges this standard 3:2 ratio of intra- to extracellular water, and assumes that everybody fits this standard. But it is important to know the exact values of intra- and extracellular water because not everybody falls into this normal range. This empirical estimation used in other BIA equipment inhibits the accuracy of the results because it gives generalizable water values, which might alter all of the other tested components’ values. BIA technology is based on the conductivity of tissue and its resistance. By only measuring partial body water instead of total body water, the results are only partially credible. The InBody is a unique device, and one of the only bioelectrical impedance analyzers on the market measuring total body water. Multiple frequencies also provide numerous impedance values, opposed to only one. The use of multiple currents ensures the accuracy of the impedance readings; the most important thing when using BIA technology.

2. Segmental Measurement Increased accuracy by producing impedance for each different segment (4 limbs and the trunk). The segmental measurement is the technology that assumes the body as five cylinders - four limbs and a trunk- and measures impedance of these parts separately. Segmental body composition analysis provides segmental measurement of body water and fat free mass. Furthermore, the analysis is highly accurate because the measured value of a certain part does not affect the measurement of other segments. It is because the conventional body composition analyzers lack accuracy in measuring body fat and cannot figure out patient’s exact body shape. It needs empirical references to correct inaccurate measured values. To ensure the accuracy of trunk impedance, it is necessary to develop precise measurement technologies. The accurate measurement of the trunk provided by the InBody heightens the accuracy of the body composition analysis. When body water is measured using a single impedance value, assuming the body to be a single cylinder, there is a high chance of error. Body mass distribution and metabolic characteristics differ between legs and trunk and cannot be identified using a single frequency, yielding a higher error rate. InBody separates the body into 5 different cylinders with respect to the arms, legs and trunk, and calculates the impedance of each. Even if body composition analyzers can measure our body segmentally, the same measurement accuracy cannot be recorded by all analyzers. Human subjects can be considered to be made up of five tubes: two legs, two arms, and one trunk. There are many factors that can affect impedance in a human subject. While the trunk makes up the biggest part of the body, its impedance index is the lowest, at about 20 ~ 25 ohms, due to the fact that it has the largest width of all body parts. In the case of arms, which usually have an impedance of about 300 ohms, 2-3 ohms can be considered a small error. However in the case of the trunk, the same 2-3 ohms can be considered a significant error capable of affecting the results of the test on the trunk, it is necessary to develop precise measurement technologies. As such, the accurate measurement of the trunk provided by the InBody can contribute to heighten the accuracy of the body composition analysis.

DSM-Direct Segmenal Measurement Biospace’s patented technology makes the

measurement absolutely accurate by checking impedance for each different segment:

4 limbs and trunk

Body Shape II

Comparison between trunk, arm, and leg impedance

Body Shape I

3. 8-Point Tactile Electrodes Enhanced accuracy and reproducibility through fixing the measuring locations of current and voltage.

The use of 8 tactile electrodes instead of the standard 4 gives the InBody the ability to measure the body segmentally instead of assuming that the body is a single cylinder. The InBody uses overlapping currents to isolate specific body parts and assess their LBM (lean body mass) independently of the others. Other analyzers measure only one portion of the body and translate the results to a generalizable value for the entire body. The use of fewer electrodes results in less accuracy and the need for external variables to aid in the analysis. As you can see, the current does not travel through the entire body with other conventional BIA methods, and therefore lack accuracy in their testing methods. The use of fewer electrodes creates less accurate and reproducible results. These machines are more sensitive to water variation in the body, and rely more on empirical data. These 8 electrodes are a key component in the process of receiving accurate, reproducible results. The electrodes are strategically placed so the currents that are emitted have the same starting and ending points every time an individual is tested. Manually placed electrodes are subject to human error and may not have the same points of entrance every time. Reproducibility is necessary in order to give an accurate body composition assessment, and Biospace’s patented 8-point tactile electrodes remove any concern of error associated with current lengths and impedance values. Validation has proved the use of tetra-polar electrodes to be the most effective way to measure body composition analysis using BIA equipment. 1The use of 2 electrodes on each hand and foot guarantees the same point of entry and exit every time a subject is tested. With manually applied electrodes it is difficult to place them exactly in the same position every time. With the embedded electrodes the currents start at the fingers or toes respectively and meet at the same point every time. This guarantees the same current lengths time after time. This feature is unique to Biospace’s technology.

8-Point Tactile Electrode Our tetrapolar 8-point tactile electrodes technology has made it possible to enhance accuracy and reproducibility by fixing the measuring points of current and voltage.

4. No Statistical Estimations on body composition analysis There is no need to use empirical estimations; gender and age do not affect the result. With Conventional BIA, results are distorted by statistics, based on personal data such as age, sex, body type, etc. Conventional BIA devices only partially measure body composition and the rest is statistically determined. Although it gives reasonable results for people of the norm, its accuracy is very low for children, elderly, patients, and athletes. However, InBody’s DSMF-BIA technology has overcome the limitations of the conventional BIA method. It accurately assesses intracellular water using multiple frequencies and measures bioimpedance of the trunk as well as the rest of the body. InBody uses actual measurements to yield accurate results regardless of empirical estimations. Examples below show some empirical estimations that are used in conventional BIA devices.

Why do other analyzers use empirical estimation? Empirical estimation refers to the application of variables estimated from the personal information input, such as gender, age and body type as in athletes or average people. For example, when body composition analysis of a female examinee is conducted, her Body Fat Mass can be estimated based on the empirical fact that women usually have more Body Fat Mass than men. Thus, empirical estimation, in order to revise inaccurate estimations, refers to those variables that may affect the result of body composition analysis. If the subject does not belong to an average group, then empirical estimation produces error. A machine using empirical estimations cannot reflect the exact compositional changes of the patients or differentiate between body compositions of different groups for research purposes. Conventional body composition analyzers need empirical data to overcome poor accuracy and reproducibility. This brings about insensitive measurement and there is difficulty detecting changes of body composition. Concerning clinical use of the body composition analyzer, sensitivity is one of the most important issues. The data is obtained by estimation rather than actual measurement. Empirical estimation will produce errors for any individuals with body shapes other than the standard ones. Because of this, conventional body composition analyzers have considerable error rates in those individuals with extreme obesity or illness, children and elderly people.

Sample example 1 Sample example 2 Other BIA body composition analyzers use empirical estimations to account for the error in

analysis. This individual only changed the gender input, and got entirely different results although their body’s composition remained the same

Customers List

Research / Education

Kuopion yliopisto, Medistudia

Kuopion yliopisto, fysiologian laitos

Kuopion Liikuntalääketieteen laitos

Savonia AMK, terveysala

Kelan tutkimus- ja kehitysyksikkö

Kansanterveyslaitos, Diabetesyksikkö

Jyväskylän yliopisto, terveystieteen laitos

Jyväskylän yliopisto, liikuntalääketieteen laitos

Oulun yliopisto

Oulun AMK, tekniikan yksikkö, (2 devices)

Helsingin yliopisto, ravitsemustieteen laitos

Lahden AMK, liikunnan laitos

Etelä-Karjalan AMK, sosiaali- ja terveysyksikkö

Kemi-Tornion AMK, sosiaali- ja terveysala

Rovaniemen AMK, sosiaali- ja terveysala

Rovaniemen AMK, liikunta- ja vapaa-aika

Spas

Naantalin Kylpylä

Ruissalon Kylpylä

Ikaalisten Kylpylä

Sports / Testing

Testaus- ja kuntotutkimusasema Tesku / Varalan Urheiluopisto

Eerikkilän Urheiluopisto

Vuokatin Urheiluopisto, Snowpolis

Stamina Trainers

Liikuntakeskus Pajulahti

Easyway Finland Oy

Easyway Finland Oy

Aquarius Sporting Club

Endurance For Life

ODL Liikuntalääketieteellinen klinikka

Finland

Kuopion yliopistollinen sairaala, kliininen fysiologia

Medical / clinical use

Kuopion yliopistollinen sairaala, fysiatrian pkl

Tampereen yliopistollinen sairaala, fysiatrian pkl

Pohjois-Karjalan keskussairaala, ravitsemusterapia

Liikunta- ja kuntoutumiskeskus Peurunka (2 devices)

Rehabilitation

Kiipulan Kuntoutuskeskus

Kunnonpaikka kuntoutus- ja virkistymiskeskus

Kruunupuisto Punkaharjun kuntoutuskeskus

Härmän Kuntokeskus

Kitinkannus Palvelukeskus

Siuntion Hyvinvointikeskus

Kaprakka Kuntoutuspalvelukeskus

Lamminniemi kuntoutuskeskus

Work medicine / Capacity

Työterveyslaitos, fysiologian os. toimintakykylaboratorio

Pelastusopisto

Keski-Uudenmaan Pelastuslaitos

Puolustusvoimat / Pääesikunta

Puolustusvoimat / Urheilukoulu

Puolustusvoimat / Laivastolääketieteen yksikkö

Puolustusvoimat / Maanpuolustuskorkeakoulu

Puolustusvoimat / Maasotakoulu

Kaarinan kaupunki, liikuntapalvelut

LIKES, KKI-projekti (3 devices)

Fitness / weight management

LIKES-tutkimusyksikkö, painonhallintaklinikka

Ideal Fit Oy

SAGA Yhtiöt

Lahden Kuntohoito Oy

Hyvinkään Hyvä Kunto

Aromatica -hoitola

Finland

The Royal Norwegian Navy

Health

Pfizer Norge

Akerhus Universitetssykehus

Ullevål Universitetssykehus

Sykehuset i Vesfold

Legekontoret for sjömenn

Fysioterpivakten

Din Kroppsanalyse

Livsstilssenteret

Dr Jon Scheldrup

Pondusklinikken

4M Klinikken

Trimit

Fitness

TIF Viking

E2

TALI

Oxigeno

Elixia Kolbotn

Spenst Kristiansand

Norway Sweden

Medical / clinical use

Karolinska University Hospital / Astrid Lindgrens Barnsjukhus

Uppsala University Hospital, Dept. Of Nutrition

Sports / Testing

National Wintersport Center, Mid Sweden University

Energikällan, Fitnesscentre

Meditech Sverige

Work medicine / Capacity Enköpingshälsan, Occupational

Health Service

Unite Kingdom

Royal United Bath Hospital, Diabetes & Endocrinology

Hospitals & Medicine

Derby City Hospital, Dept of Nephrology

Hammersmith Hosp.Dept of Dietetics & Nutrition

London Medical

Kings College Hospital, Dept of Nephrology

North Staffordshire, Dept of Nephrology

Royal Free Hospital, Dept of Nephrology

Walsgrave University Hospital, Dept of Obstetrics

University College Hospital, Dept of Bariatrics

Aston University, Appetite & Behaviour Lab

Universities London Metropolitan University, Studies into Obesity

Leeds University, Appetite & Behaviour Lab

Covance, Pharmaceutical Testing Lab

Industry

Goldshield Pharmaceuticals

Northern Health, Occupational Health

Pepwalk, Occupational Health

Unilever, Research & Development Dept

Fitness Area

Alive & Well

Beechdown Health & Fitness Club

Easy Exercise

Liverpool City Council

Newcastle City Council

One Aldwych Hotel Spa & Gym

Shape up & Go

Beauty

Harrods Spa

UR Beautiful

Grayshott Hall Hotel & Health Spa

School

Monkseaton High School

University College School

Physiotherapist Physio Nation

Turkey

Bahar Demirk?an Diethican Clinic

BeautyLady

Esthetics Center

Betty

Biolaser

Dr.Emre ??k

Fizmer

Harem

STS SA?

ASM

Hospital

Avicenna

Bing? Devlet

Ekol Hastanesi

Hisar Hastanesi

International Hosp.

Kartal Umut Hast.

Ordu Devlet Hast.

Ozel Kastamonu Hast.

Sema Hastanesi

Ya?m Hastanesi

Ya?m Hastanesi

Yasam Hastanesi

ARMY

K.K.K - S.A

K.K.K - S.A

K.K.K - S.A

Clinic ?ranTip

Asil Onay

Hospital (University)

Istanbul Medical Fac.

Physiotherapy Clinic

Therapy Art

Sports Center Mayadrom

Sports Chain

Sports Int'l

Sports Int'l

Sports Int'l

Sports Int'l

Sports Club

Modem Tic

Modem Tic

Perfetto

TED

University ??

Etc.

Beautyland

Hisar Intercontinental Hospital

ÖFA Ltd.Şti., GNC Doğal Beslenme Ürünleri

Sema Hastanesi, International Hospital

China

Beijing Competitor Healthful Food Co., Ltd.

Si Chuan Province Sports Center

Guang Dong Province Sports Center

Zhe Jiang Province Sports Center

Shan Dong Province Sports Center

Hu Nan Province Sports Center

shanghai Sports College

Shen Zhen Sports Institute

Beijing Sports Science Institute

Shanghai Sports Center

Shanxi Sports Center

Hangz Zhou Team No.1 Training Center

shanghai Sports Institute

Beijing Yihui Women Club

Beijing Hospital

China Army No.3 Medical University Southwest Hospital

China Army N0.l4 Medical University Xijing Hospital

GuangZhou Huang Pu Hospital

Shanghai Sports Center

GuangZhou Jing Heng Rehabilitation Center

China Army N0.159 Hospital

GuangDong PanYu Hospital

GuiYang N0.3 Hospital

DaLian N0.2 Hospital

GuangZhou N0.6 Hospital

China Sports Medicine Research General Center

Osaka University Hospital

Kurume University

Keiogijuk University

Rousai Hospital

Aijinkai Hospital

Toranomon Hospital

Sendai University

Kawasima Clinic

Renaissance Fitness Club

Tipness Fitness Club

Sport Oasis Fitness Club

Central Sport

SONNY Co., Ltd.

TOYOTA Co., Ltd.

MASTUSHITA Co., Ltd.

KAOU Co., Ltd.

SANTORY Co., Ltd.

Japan

Ulisses Silveira

João Ricardo Maia de Aguiar

Roberto Constâncio Vieira Neto

Corpore Medicina Estética Clínica

Daniela Hueb

Dr. Mauro Kleber

Minas Tênis Clube

Norberto Paes Campos

Prima Forma Medicina Integrada S.A

Prima Forma Medicina Integrada S.A

Vital Medicina e Nutrição Clinica

Medicorpo - Brasília

Sílvia Leite Campos Martins

Mary Geil

Prof. César Assad. K. Filho

Clínica Toi

Clinica Dr. Bibiano

Clínica Boulevard

Dr. Emerson Tobias Fischer

Dra. Manuela Macedo

Sérgio Paulo Aguilera Machado

Marco Aurélio Lenzi

Corporall

Corporall

Generoso Martins das Neves

Fátima Helen Pegorim Magacho

Daniely Torres Catharino

Paulo Rosa Pereira - Academia Natanael

Júlio Cesar Budal Arins

Lucia K. Yuyama

Marilia Pollon Pelissari

Instituto de Cirurgia Dr. Sandro Scolari

Giseli Fátima I. Pereira

Brazil

Esplenda Centro de Medicina do Corpo Ltda

Soraya Victoriense Cunha

Claúdia da Silva Guedes Calvano

Cláudio Corá Mottin

Orlndo Knoll Lopes

Orlndo Knoll Lopes

Orlndo Knoll Lopes

Dra. Dora Ullmann

Sociedade Brasileira de Medicina Estética

Clínica Sensi Ka

Dr. Dudson Pegoin Magacho

Edmar Fontoura Lopes Neto - Clínica Plastiqué

Alberto R. Serfaty

Labs Check-Up e Medicina Preventiva

Ricardo Alberto Benevides

Fernando Nunes Pitanga

Cristiano Marcelo Escolástico Ribeiro

Aline Maria Swarowssky

Med. Funcional S/C Ltda Clin. Med. Int. Reab. Func. S/C

Núcleo de Cirurgia Geral e Digestiva

Joel Antônio da Silva

Centro Maranhense de Cirurgia Plástica e Estética Médica

Pellegrini e Aguiar Clinica

Ganep

Antônio Pacileo Cruz

Hortensia Cosméticos e Participações S.A. Daslú

Centro Médico Baronesa de Itú

Rondó Medical Center

Dr. Samir Abdel Latif Serviços Médicos Ltda

Clínica Charles Yamagushi

Clínica de Nutrição Dr. Lara

Clínica Dr. Reinaldo Monteiro

Academia Ponto 1- Wanderson

Einstein Hospital,

S-studio, s.r.o.

Státní léčebné lázně Bludov

MUDr. Dagmar Prokešová

FITNESS PLAZA

FITNESS GOLDSGYM

Fakulta sportovních studií - MU

BIG ONE FITNESS

Studio Milery Sun

Hotel INTERNATIONAL

Akuna CZ s.r.o.

Ing. Jiří Adamík fitness

Dům Salve s.r.o.

DIETOLOGICKÉ A OBEZITOLOGICKÉ CENTRUM SAVELA

Gastroenterologie s.r.o.

Fakulta vojenského zdravotnictví UO

Priessnitzovy léčebné lázně a. s.

Regenerační Centrum Srdíčko

Czech Republic

MUDr. Ivan Majercák Centrum pro lécbu obezity

Lázně Dolní Lipová

MUDr. Nadežda Šišáková - TEMPUS

Fakulta tělesné kultury Univerzita Palackého

Julia Matiašková

Arcadia medica

FITNESS studio KWK

Resort Svatá Kateřina

FITNESS Oasis CITY

Studio Modelace

FITNESS WORLDCLASS

Studio Vanda

FITNESS I M FIT

Margita Šimorková

Mudr. Dobrovolný

MUDr. Robin Urbánek Centrum pro lécbu obezity

REGE - CENTRUM, s.r.o.

Center for nutrition

Glory medical Center & Weight Loss clinic

Medical Group of Culver City

Tallgraa General & vascular Surgery

Temple Pain Therapy Center

Humax Medical Group

University of Southern California

Aquarius Water

Texas Institute of Anti-Aging Medicine

Cosmetic Plastic Surgery Specialists

Philip O Warner's Office

Newport Medical Consultants

Joan Temmerman MD

Jenny Craig

Michigan Mesotherapy Institute

Brookdale University Hospital & medical Center

Huey Doyle W. MD

The Physicians Centre

Wellquest

Vally View Medical Clinic

Beverly Hills Anti-Aging Group

Pump 24hr. training mecca LLC

24 hour fitness(WA)

Dr. James Peters, Purnachandra Yerneni, M.D.

U S A

IKR Production Development Plc.

Bureau of Taxation and Financial Control

Children’s Hospital in Buda

COIN WORKS 2000 Kft. Heim Pál Children’s Hospital

Ideal Body Kft.

Hungarian Foundation for Kidney

Medrepked Kft.

National Institute for Development of Junior Players and for other Sport Services

Nestlé Hungária Kft.

National Institute for Sport and Health

Pro Sanita Kft.

Salus Aegroti Foundation

University of Debrecen Center of Medical and Health Sciences

HANKOOK

Foundation for Development of Junior Players

University of Western Hungary, Apáczai Csere János Branch

Vitacard – V Kft.

AD SANITATEM BT.

Lifestyle Advisor Mrs. Attila Demeter - Herbalife

Med. Dr. Hubert János

„Foundation for Diabetic People

Meditechnik Bt.

University Semmelweis Children's Clinic

Hungary

Nat'l Taiwan Normal Univ.

Nat'l Yang-Ming Med. Univ.

Nat'l Tainan Teachers College

Nat'l Taichung Teachers College

Chia-Tzu Youth Camp

President Health World

Kong-Nin Nursing College

Fu-Tai Clinics

Tri-Service General Hospital

Army Force Sung Shan Hospital

National Taiwan Normal Univ.

Yoya Clinic

Metee Clinic

Chinese Culture Univ.

National Taiwan Sports College

Chia-Nan Pharm.Tech. Univ.

Yeh Ming-Hong Surgery

ChangHua Christian Hospital.

Mackay Memorial Hospital.

V.G.H-Taichung

Hurray Party

Twain

Nat'l Cheng-Kung Univ.

Mackay Memorial Hospital

Nat'l Cheng-Kung Univ.

Chang-Gung M.Hosp-Kaoshiung

Nat'l Taitong Teachers College

Nat'l Zhongxing Hospital

Ziji Art College

Sanzong Total Hospital

Taipei Medical Univ.

Mackay Memorial Hospital

Min-Sheng Hospital

Kang-Ning Hospital

Yu-Sheng Hospital

Nat'l Gao-Xiong Univ

Ke-Wei Company

Nat'l Sports College

Tan-Jiang Univ

Yong-Yuan Keji College

XingZhengYuan Sports Weiyuanhui

City Jilong Hospital

Shu-Li Miaoli Hospital

MeiDeng Feng

Gold's Gym – Gym 6th of October City

University of Alexandria, Research Institute

Bodhi Gym

World Gym

Dr. Randa Reda

Helwan University , Faculty of Physical education

Dr. Hisham El-Minawy

Fitness & Dance Academy

Dr. Ihab abu El-Naga

Our Gym

Dr. amr Soliman

Sheraton Hotel, Cairo

Healthy Life, Dr. Ahmed Noer

Abbott Pharmaceutical Company

El-Masa Gym, Armed Forces

EVA Pharma Company

Gold's Gym, Sheikh Zayed City

Dr. Iman Asser, Alexandria

Wham, Dr. Waffaa Mehelba, Alexandria

El-Resala Hospital

E g yp t

Instituto Mexicano del Seguro Social

Comisión Nacional de Cultura Física y Deporte

INSAR. Institute for Cardiac Arrhytmias and Cardiovascular Diagnosis

Instituto Nacional de Rehabilitación

TELETON

Desarrollo Integral de la Familia

Universidad Nacional Autónoma de México

Universidad Autónoma del Estado de México

Universidad Autónoma de Yucatán

Universidad Veracruzana School of Nutrition

Sport World

Universidad del Valle de México

DADIAL S.A. DE C.V.

SISTEMA PARA EL DESARROLLO INTEGRAL DE LA FAMILIA

INSTITUTO NACIONAL DE ENFERMEDADES RESPIRATORIAS (INER)

DR. FERNANDO DEL CAMPO

INSTITUTO SINALOENSE DEL DEPORTE

M e x i c o

Singapore General Hospital

Gleneagles Hospital

Executive Health Screeners

Meridian Clinic

Green Club

London Research Center

Evangel Family Clinic

Marie France Bodyline

Well Life Pte Ltd

Smitech(Asia) Pte Ltd.

ДКЦ 2 ЕООД, Пловдив

“Promedica” – Macedonia

ДКЦ "РАЛИС”

УСБАЛЕ, клиника по диабетология

БОРЕКС 3

Eлкомерс Вяра ЕООД – Варна

СМК ООД Варна

S i n g a p o r e B u l g a r i a

McGill University

Montreal General Hospital

The Research Institute of the MUHC

Vancouver Laser & Skin Care Centre

24 hour fitness

C a n a d a

City Clinic

Univ. Kebangsaan

TUDM Army Camp

National Sports Council

Marie France Bodyline

M a l a ys i a

Tarakan Hospital

PT. Dipa/Indonesia

DINAS KESEHATAN TNI

SURABAYA

RUMAH SAKIT RK. CHARITAS

Palembang

National Olympic Committee

Gilan University

Sports Science Faculty Training Sabzewar Univ.

Yazd University

SOMATCO

Kingdom Hospital

Diet Center

Dr. Nutrition

Dr. Anthony Torbay, Alpha-Tech, Renobelle

Labib Medical Center, Dr. Hisham Nazar

Dr. Richard Yazbeck Lebanese Hospital

I r a n

I n d o n e s i a S a u d i A r a b i a

L e b a n o n

Pro-Med Techonology Ltd.

H.K.Polytechnic University

Private Coach

Physical Ladies Club

Thanes Development

Chevasom Health Resort

Thanes Development

Slimming Center

Hospimedica

All India Institute of Medical Sciences

Le Rouge

Edgar H Moreno MD, Pana-Health

Dr. Max Brenes, GNQ Anti-Aging Univ.

Flinders University Medical Center, Dr. Mark Doyle, Prof.N Piller

H o n g K o n g

I n d i a

C e n t r a l A m e r i c a

T h a i l a n d

P e r u

A u s t r a l i a

Testimonial

“We purchased a Biospace InBody machine for our weight control center in August of 2005.

I must say that the response has been outstanding.

It allows us to determine protein needs by making sure that our patients are losing fat and not muscle.

We also measure intra- and extracellular fluid.

This has been a tremendous tool for us to help patients better understand their weight program and

comply with the protocol.”

------------------------------------------------------------------------------------------------------------------------ Diane Kallmann, RN, Administrator

Medifast Medical Center Sacramento, CA

Phillip O. Warner, M.D.

New Dimensions Medical Group Marysville, CA

“The InBody has been an incredible asset to our practice.

The information provided by the machine is both very accurate and helpful to patients.

We have had several patients who had underwater weighing prior

to using our InBody and the results were almost identical.

In addition, the InBody s impedance index allows a patient

to fine tune their work-out to create better body proportion.

The Biospace unit is simple to use, takes very little time, and yet provides a very impressive report.

The machine has worked flawlessly since we purchased it.

In addition, the support staff has been very helpful in answering questions

and educating us on interpreting results.

We previously used a handheld device but found the results to be very inaccurate,

non-reproducible and provided only BMI and percent body fat.”

---------------------------------------------------------------------------------------------------------------------------------- Jeffrey I. Barke, M.D.

Fellow, American Academy of Family Physicians Newport Medical Consultants-Personal Physicians

Newport Beach, CA

“Most of clients who have used InBody are satisfied with it.

The exercise program is being planned by this InBody result.

As they see the changed result, they estimate their present health status.

Our club has accumulated each result so it is available to compare previous result with

present result when the member who checked

InBody come again.

Average 5-10 members use this instrument in a day.

I would like to recommend this instrument to INTERCONTI HOTELS personally.”

----------------------------------------------------------------------------------------------------------------------- S. S. Kim

Metropolitan Fitness Club Manage

Interconti Grand Seoul, Korea

Testimonial

“InBody BS1,0, a Multiple Frequency Bedside BIA Instrument as used in Different Volume

Replacement Strategies on Body Fluid Compartments in Patients undergoing Major

Abdominal Surgery.”

----------------------------------------------------------------------------------------------------------------------- Katrin Lang

Department of Anesthesiology and Intensive Care Medicine, City Clinic Ludwigshafen, Academic Teaching Hospital of the University of Mainz,

Germany

"We use the apparatus In Body 720 as a supplement of functional

body analysis in the research measurements of

different population groups (patients, sportsmen, ordinary population)

in the different age groups (seniors, adolescents, and children).

The technology is advanced.

The exit from software is interesting, lucid and intelligible to clients."

----------------------------------------------------------------------------------------------------------------------- Doc. RNDr. Miroslava Přidalová, Ph.D.

Department of Functional Anthropology and Physiology,

Faculty of Physical Culture

Palacký University Tř. Míru 115 771 41 Olomouc Czech Republic

“I would like to express the maximum gratification with InBody720.

The machine represents high benefit for evaluation of body composition in medical

education as well as in research.”

----------------------------------------------------------------------------------------------------------------------- Assoc. prof. Ludmila Sevcikova, MD., PhD.

Institute of Hygiene Faculty of Medicine,

Comenius University Bratislava, Czech Republic

“At our University site is InBody720 machine used for both research and treatment of

obese patients. InBody720 very relieves our work with patients.”

----------------------------------------------------------------------------------------------------------------------- Ing.Hana Stritecka PhD

University of Defence,faculty of Military Health Scienc,e

Czech Republic

2. Nephrology

Kanazawa Y, Nakao T, Matsumoto H, Okada T, Hidaka H, Yoshino M, Shino T,

Nagaoka Y, Takeguchi F, Iwasawa H, Tomaru R. Serial changes in body composition

in patients with chronic renal failure on peritoneal dialysis. Nippon Jinzo Gakkai Shi.

2001 Oct;43(7):589-94. [Article in Japanese]

Lee SW, Song JH, Kim GA, Lee KJ, Kim MJ. Assessment of total body water from

anthropometry-based equations using bioelectrical impedance as reference in Korean

adult control and haemodialysis subjects. Nephrol Dial Transplant. 2001 Jan;16(1): 91-

7.

3. Lymphology

Harris R, Piller N. Three case studies indicating the effectiveness of manual lymph

drainage on patients with primary and secondary lymphedema using objective

measuring tools. J. Bodywork and movement therapies. 2003 Oct;7(4):213-21

Moseley A, Piller N, Carati C. Combined opto-electronic perometry and bioimpedance

to measure objectively the effectiveness of a new treatment intervention for chronic

secondary leg lymphedema. Lymphology. 2002 Dec;35(4):136-43.

4. Orthopaedics

Segal NA, Toda Y. Absolute reduction in lower limb lean body mass in Japaness

women with knee osteoarthritis. J Clin Rhematology 2005 Oct;11(5): 245-9.

Segal NA, Hein J, Basford JR. The effects of pilates training on flexibility and body

composition: an observational study. Arch Phys Med Rehabil. 2004 Dec;85(12):1977-

81

Lim S, Joung H, Shin CS, Lee HK, Kim KS, Shin EK, Kim HY, Lim MK, Cho SI.

Body composition changes with age have gender-specific impacts on bone mineral

density. Bone. 2004 Sep;35(3):792-8.

Choi JW, Pai SH. Association between respiratory function and osteoporosis in preand

postmenopausal women. Maturitas. 2004 Jul 15;48(3):253-8.

Choi JW, Pai SH. Bone mineral density correlates strongly with basal metabolic rate in

postmenopausal women. Clin Chim Acta. 2003 Jul 1;333(1):79-84.

Toda Y, Segal N, Kato A, Yamamoto S, Irie M. Correlation between body composition and efficacy of lateral wedged insoles for medial compartment osteoarthritis of the knee. J Rheumatol. 2002 Mar;29(3):541-5.

Product Validation Study

Medici G, C Mussi, Fantuzzi AL, Malavolti M, Albertazzi A and Bedogni G.

Accuracy of eight-polar bioelectrical impedance analysis for the assessment of total and

appendicular body composition in peritoneal dialysis patients. Eur J Clin Nutr. 2005

Aug;59(8) : 932-935.

Sartorio A, Malavolti M, Agosti F, Marinone PG, Caiti O, Battistini N, Bedogni G.

Body water distribution in severe obesity and its assessment from eight-polar

bioelectrical impedance analysis. Eur J Clin Nutr. 2005 Feb;59(2):155-60.

Malavolti M, Mussi C, Poli M, Fantuzzi AL, Salvioli G, Battistini N, Bedogni G.

Cross-calibration of eight-polar bioelectrical impedance analysis versus dual-energy X-

ray absorptiometry for the assessment of total and appendicular body composition in

healthy subjects aged 21-82 years. Ann Hum Biol. 2003 Jul-Aug;30(4):380-91.

Bedogni G, Malavolti M, Severi S, Poli M, Mussi C, Fantuzzi AL, Battistini N.

Accuracy of an eight-point tactile-electrode impedance method in the assessment of

total body water. Eur J Clin Nutr. 2002 Nov;56(11):1143-8.

Cha K, Shin S, Shon C, Choi S, Wilmore DW.

Evaluation of Segmental bioelectrical impedance analysis (SBIA) for measuring muscle

distribution. J ICHPER. SD-ASIA. 1997 11-4

Clinical Application

1. Nutrition

Huang Q, Nai YJ, Jiang ZW, Li JS. Change of the growth hormone-insulin-like growth

factor-I axis in patients with gastrointestinal cancer: related to tumour type and

nutritional status. Br J Nutr. 2005 Jun;93(6):853-8.

Choi JW, Pai SH. Brief communication: Respiratory function is closely associated with

basal metabolic rate in elderly persons. Ann Clin Lab Sci. 2004 Winter;34(1):99-102.

Koo JR, Yoon JY, Joo MH, Lee HS, Oh JE, Kim SG, Seo JW, Lee YK, Kim HJ, Noh

JW, Lee SK, Son BK. Treatment of depression and effect of antidepression treatment

on nutritional status in chronic hemodialysis patients. Am J Med Sci. 2004 Jul;329(1):1-

5.

Wang XB, Ren JA, Li JS. Sequential changes of body composition in patients with

enterocutaneous fistula during the 10 days after admission. World J Gastroenterol.

2002 Dec;8(6):1149-52.

Research Treatise as of November, 2007

8. Laboratory Reports and Posters

Alexandridis J, Cuntz U, Ehrig C, Huber G, Roseneck Medical and

Psychosomatic Clinic, Institue for Sports Sciences University of Heidelberg.

Evaluation of an outpatient psycho-educative exercise programme for obsess men

and women. 2005 June, ECO

Kovacs VA, Fajcsak Zs, Gabor A, Martos F, National Institute for Sports

Medicine, Budapest, Hungary. Changes in body composition improve insulin

sensitivity in obese children. 2005 June, ECO

Katrin Lang, Department of Anesthesiology and Intensive Care Medicine,

Klinikum der Stadt Ludwigshafen, Akademisches Lehrkrankenhaus der

Universitat Mainz. The effects of different volume replacement strategies on body

fluid

compartments in patients undergoing major abdominal surgery. 2005

Northern Health and Fitness Assessments. Report on the health and fitness

analysis of pupils at a North Tyneside primary school. 2005 April

Bianca Wong, Kate Wylie, Tim Nguyen, Stephen Murdoch, Janusz Krolikowski.

Investigating lifestyle impact on manual handling injury. GEMP year 2, Flinders

University, Adelaide. 2002

Cho-il Kim, Haeng-Shin Lee, Hae-jeung Lee, Seon Joo Park, Haymie Choi.

Nutritional Status of the Korean Elderly Assessed by Semi.Quantitative Food

Frequency Questionnaire. 26th National Nutrient Databank Conference. June, 2002

Thomas EL, Frost G, Harrington T, Bell JD. Validation of InBody bioelectrical

impedance by whole body MRI. 2001

Pahtaja Visa, Hamalainen Pekka, Leppanen Tero. Exercising senior citizen’s

balance and motor coordination. MOTO+ Project. Finland

Hamalainen Pekka, Pahtaja Visa. The effects of playground activities and exercising

on playground equipment on the motor coordination of preschool children. MOTO+

Project. Finland

Chyi T, Huang YC, Wong SH. Effect of consuming strategies on body fluid balance

and blood sugar concentration with carbohydrate-electrolyte beverage in young

soccer players under heat stress. Chinese Culture University, Taipei, Taiwan.

Toda Y. The effect of energy restriction, walking, and exercise on lower extremity lean

body mass in obese women with osteoarthritis of the knee. J Orthop Sci.

2001;6(2):148-54.

Toda Y, Segal N, Toda T, Morimoto T, Ogawa R. Lean body mass and body fat

distribution in participants with chronic low back pain. Arch Intern Med. 2000 Nov

27;160(21):3265-9.

Toda Y, Segal N, Toda T, Kato A, Toda F. A decline in lower extremity lean body

mass per body weight is characteristic of women with early phase osteoarthritis of the

knee. J Rheumatol. 2000 Oct;27(10):2449-54.

Toda Y, Kobayashi T. The usefulness of walking for preventing sarcopenia in dieting

postmenopausal women complaining of knee pain. Ann N Y Acad Sci. 2000

May;904:610-3.

5. Internal Medicine

Jianfeng G, Weiming Z, Ning L, Fangnan L, Li T, Nan L, Jieshou L.

Serum citrulline is a simple quantitative marker for small intestinal enterocytes mass

and absorption function in short bowel patients. J Surg Res. 2005 Aug;127(2):177-82.

Kotoh K, Nakamuta M, Fukushima M, Matsuzaki C, Enjoji M, Sakai H, Nawata H.

High relative fat-free mass is important for maintaining serum albumin levels in patients

with compensated liver cirrhosis. World J Gastroenterol. 2005 Mar 7;11(9):1356-60.

Lee WC, Chen JJ, Hunt DD, Hou CW, Lai YC, Lin FC, Chen CY, Lin CH, Liao YH,

Kuo CH. Effects of hiking at altitude on body composition and insulin sensitivity in

recovering drug addicts. Prev Med. 2004 Oct;39(4):681-8.

6. Bariatrics

Kiyama T, Mizutani T. Okuda T. Fujita I, Tokunaga A, Tajiri T, Barbul A.

Postoperative changes in body composition after gastrectomy. J Gastroinest Surg.

2005 Mar;9(3):313-319

7. Comparison

Demura S, Sato S, Kitabayashi T. Percentage of Total Body Fat as Estimated by

Three Automatic Bioelectrical Impedance Analyzers. J Physiol Anthropol Appl Human

Sci. 2004 May;23(3):93-9.

Cert i f icate

CE0120 ISO9001 ISO13485 FDA UL