biomarker base™ introduction
TRANSCRIPT
Unified Data for Actionable Biomarkers
What Is BiomarkerBase? • A manually curated database
that aggregates information from publicly available sources that describe the clinical use of biomarkers.
• Provides access to biomarkers that can’t be found through searches in public sources.
• Links biomarker information together by target, disease, drug, therapeutic area, and company.
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http://www.biomarkerbase.com
- IVD Tests cleared or approved by FDA since the end of 2002 that utilize one or more biomarkers.
- Drugs, all FDA-approved, that include a biomarker in the label.
- Clinical Trials, phase 3 and 4, initiated since the end of 2011, which include “marker” in the record. Phase 2 trials by Nov ‘13.
- Publications describing clinical studies that include biomarkers from the sources above.
Current Datasets
Biomarker Definition: A nucleic acid, peptide or hormone that is potentially useful
for diagnosis, prognosis, or companion diagnosis.
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Public sources of biomarker information lack
connectivity and have severe querying
limitations.
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Query limitation #1: Some of the most critical information can’t even be searched.
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Query limitation #1: Some of the most critical information can’t even be searched.
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Query limitation #2: Nomenclature isn’t standardized.
Search Term
Studies Returned
ca 125 153
ca-125 140
mucin-16 138
mucin 16 138
MUC16 0
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BiomarkerBase Difference
Manually Curated
Comprehensive
Clinically Focused
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Who Uses BiomarkerBase?
Diagnostic Companies Product development; business development; marketing
Drug Companies Clinical trial planning; partnering; test selection
Life Science Companies Product development; business development; marketing
Research Institutions Licensing
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Subscription Pricing
Single User • $1,000 / year
• Access for one individual
Multi User • $2,500 / year
• Unlimited users at a single site within one company or institution
• Multi-site licenses are also available at discounted pricing.
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Amplion Research Inc. 1011 SW Emkay Drive, Suite 200 Bend, Oregon 97702 USA [email protected] +1.503.389.1157
Contact Information
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