bioinformatics the human genome project - bioteach.ubc.ca · Ðork september 3, 2007 a team led by...

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Page 1: Bioinformatics The Human Genome Project - bioteach.ubc.ca · Ðork September 3, 2007 A team led by J, Craig Venter, abcwe, has the first mapping of a full, or diploid, genome, made

Bioinformatics+

The Human Genome Project

Page 2: Bioinformatics The Human Genome Project - bioteach.ubc.ca · Ðork September 3, 2007 A team led by J, Craig Venter, abcwe, has the first mapping of a full, or diploid, genome, made

February 2001: Completion of the Draft Human Genome

The Human Genome Project

April 14, 2003:

The Human Genome is completed – again!

October 2004 - present:

The Human Genome is now really finished!

Page 3: Bioinformatics The Human Genome Project - bioteach.ubc.ca · Ðork September 3, 2007 A team led by J, Craig Venter, abcwe, has the first mapping of a full, or diploid, genome, made
Page 4: Bioinformatics The Human Genome Project - bioteach.ubc.ca · Ðork September 3, 2007 A team led by J, Craig Venter, abcwe, has the first mapping of a full, or diploid, genome, made

To carry the sequence of my genome in my pocket, I need:

(A) supercomputer

(B) my laptop (brand new)

(C) my home computer (Oops, it’s old)

(D) DVD

(E) CD

(F) floppy disk

If compressed, the 3GB human genome

will also fit on a single CD

Page 5: Bioinformatics The Human Genome Project - bioteach.ubc.ca · Ðork September 3, 2007 A team led by J, Craig Venter, abcwe, has the first mapping of a full, or diploid, genome, made

The Human Genome…By the Numbers

• 75-100 trillion…Cells in the human body

• 3.1 billion…Base pairs in each cell

• 2.4 million…Base pairs in the largest human gene

• 28,000-35,000…Genes in the human genome

• 46…Chromosomes in each cell

Page 6: Bioinformatics The Human Genome Project - bioteach.ubc.ca · Ðork September 3, 2007 A team led by J, Craig Venter, abcwe, has the first mapping of a full, or diploid, genome, made

maps.google.ca

Page 7: Bioinformatics The Human Genome Project - bioteach.ubc.ca · Ðork September 3, 2007 A team led by J, Craig Venter, abcwe, has the first mapping of a full, or diploid, genome, made

Let’s Look at the Human Genome...

Page 8: Bioinformatics The Human Genome Project - bioteach.ubc.ca · Ðork September 3, 2007 A team led by J, Craig Venter, abcwe, has the first mapping of a full, or diploid, genome, made

Google “Genome Browser”

Page 9: Bioinformatics The Human Genome Project - bioteach.ubc.ca · Ðork September 3, 2007 A team led by J, Craig Venter, abcwe, has the first mapping of a full, or diploid, genome, made

Doing a Search

Page 10: Bioinformatics The Human Genome Project - bioteach.ubc.ca · Ðork September 3, 2007 A team led by J, Craig Venter, abcwe, has the first mapping of a full, or diploid, genome, made

Moving Around

Page 11: Bioinformatics The Human Genome Project - bioteach.ubc.ca · Ðork September 3, 2007 A team led by J, Craig Venter, abcwe, has the first mapping of a full, or diploid, genome, made

Websites visited:

• Google www.google.ca

• Google Maps http://maps.google.ca

• UCSC Human Genome Browser Gateway

• http://genome.ucsc.edu/cgi-bin/hgGateway

• (hint: use google to look up “Genome Browser”)