bioinformatics : science that derives information from computer analysis of biological data

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Bioinformatics: Science that derives information from computer analysis of biological data Data: 1) Information from genomes / genetic code 2) Biochemical results, patient statistics, etc. 3) Scientific literature Information flow: Input Storage Retrieval Data analysis Concepts of computational science, statistics, mathematics, linguistics, biological sciences... Hypothesis Data Deductive process Inductive process Bioinformatics refers to the creation and advancement of algorithms, computational and statistical techniques, and theory to solve formal and practical problems posed by or inspired from the management and analysis of biological data. Computational biology refers to hypothesis-driven investigation of a specific biological problem using computers, carried out with experimental and simulated data, with the primary goal of discovery and the advancement of biological knowledge

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Bioinformatics : Science that derives information from computer analysis of biological data. Information flow:. Input. Storage. Retrieval. Data analysis. Concepts of computational science, statistics, mathematics, linguistics, biological sciences. Hypothesis. Inductive process. - PowerPoint PPT Presentation

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Page 1: Bioinformatics : Science that derives information from computer analysis of biological data

Bioinformatics: Science that derives information from computer analysis of biological data

Data:1) Information from genomes / genetic code2) Biochemical results, patient statistics, etc.3) Scientific literature

Information flow:Input Storage Retrieval

Data analysis

Concepts of computational science, statistics,mathematics, linguistics, biological sciences...

Hypothesis

Data

Deductiveprocess

Inductiveprocess

Bioinformatics refers to the creation and advancement of algorithms, computational and statistical techniques, and theory to solve formal and practical problems posed by or inspired from the management and analysis of biological data.

Computational biology refers to hypothesis-driven investigation of a specific biological problem using computers, carried out with experimental and simulated data, with the primary goal of discovery and the advancement of biological knowledge

Page 2: Bioinformatics : Science that derives information from computer analysis of biological data

Diego Sánchez

Instituto de Biologia y Genética MolecularUniversidad de Valladolid-CSICC/Sanz y Forés s/n47003 Valladolid

Tfno: 983-184814Fax: 983-184800E-mail: [email protected]

Page 3: Bioinformatics : Science that derives information from computer analysis of biological data

Databases (raw and curated-annotated data)

Sequence and structure databases (DNA and proteins):Sequence and structure databases (DNA and proteins):

General DB: GenBank, Protein structure (PDB), SwissProt, ESTdb, SNPs…Genome DB: Human Genome; Mouse…Organism-specific: Flybase; ACEDB; Zebrafish…

Scientific literature:Scientific literature: Pubmed, Medline

Zoology:Zoology: Taxonomy, Tree of life

Relational DB: HomoloGene; CDD; Prosite...

Global and relational DBGlobal and relational DB:: Entrez; Ensembl; GOdb…

Web-based analysis platforms

NCBI; ExPASy; EBI…

Page 4: Bioinformatics : Science that derives information from computer analysis of biological data

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