biohazard containment facilities - ghdonline · •one-way passage • enter bsl-3 lab from one...
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Biohazard ContainmentFacilitiesPlanning & Design Considerations
Part 2: Design Concepts
Janet Baum, AIA
Biohazard ContainmentFacilitiesPlanning & Design Considerations
Part 2: Design Concepts
Janet Baum, AIA
• Hazard zoning• Egress in direction of lower hazard• Zone from clean to dirty• Separate hazards that may interact• Isolate highest hazard processes and agents
Prep LabPrep LabExit
Highest HazardLowest Hazard
Air Flow Contaminated
Hot ZoneHot ZoneHazard
BSL-3 Facility Planning IssuesDesign Concepts
Enter
• One-way passage• Enter BSL-3 lab from one passage, exit from another• Sequential work flow, if possible• Reduce intersections in circulation pathways
Path of Travel
ENTRY
EXIT
Process#1
Process#1
Process#5
Process#5
Process#4
Process#4
Process#3
Process#3
Process#2
Process#2
BSL-3 Facility Planning IssuesDesign Concepts
• Suites
• Cluster support functions around basic BSL-3 work zone to reduce distances between functional zones
• Good for repetitive functions and processes
BSL-3 Facility Planning IssuesDesign Concepts
Cell CultureRooms
Air Lock
Accessioning
Decon
BSL-3
Equipment
SamplePrep
BSL-3
Decon
Degown
ALBSL-2
AL
Gown
CellCulture
BSL-3
Decon
Degown /Shower
AL
BSL-2 AL
Gown
BSL-3 CellCulture
MicroTestAL
Graphic Program Blocking Diagram
BSL-3 Facility Planning IssuesDesign Concepts
BSL-3
Decon
Degown
AL
BSL-2 AL
Gown
BSL-3 CellCulture
MicroTestAL
Flow Diagram
Personnel Supplies
Infectious Agent / Waste MaterialAnimals
BSL-3 Facility Planning IssuesDesign Concepts
• Locate biosafety cabinets and fume hoods out of traffic
• Develop understanding on how to deal with emergencies within BSL-3
• Understand how to manage emergencies from outside
• Investigate how BSL-3 can expand in future
BSL-3 Facility Planning IssuesDesign Concepts
• Understand how laboratory can be cleaned easily
– Shape of each space is simple (minimize corners)
– Finishes are seamless, smooth and coved
– Equipment is located so floor can be cleaned
• Understand overall health & safety issues in BSL-3
– Ergonomics
– Visibility of all parts of lab
– Communications
– Safety equipment located in critical areas
BSL-3 Facility Planning IssuesDesign Concepts
Renovated garage with BSL-3+ for HIV test kit production
BSL-3 Facility Planning IssuesDesign Concepts
Autoclave
Autoclave
Renovated research building for HIV research - large-scale
BSL-3 Facility Planning IssuesDesign Concepts
AFIP BSL-3
BSL-3 Facility Planning IssuesDesign Concepts
Emerg.Exit
Gas Cylinder Closet
Entry
GownJCl WCShower
BSL-3 Lab
EquipmentLab
AutoclaveAir
LockMechanical
PrepLab
Equipment
FumeHood