Biochemical Processes and products

An overviewBy John Krijgsman @ biogonaal

Content

1.

Colours of biotechnology

Why biotechnology

Products of biotechnology

World production of some bioproducts

Price (erosion) of pharmaceutical proteins

Structure of bio(chemical) processes

"Catalysts" in biotechnology

The essential components of a fermenter

Infrastructure of a fermenter

Medium scale fermentation plants

White (industrial) biotechnology: biofuel pathways

White biotechnology: Bio ethanol from molasses (C6)

White biotechnology: bio ethanol from lignocellulose

Products of RED biotechnology

Discovery of penicillin

The mold: Penicillium chrysogenum

Penicillin rediscovered in Delft at the NG&SF

Structure of penicillin

Penicillin fermentation plant

Penicillin recovery

Antibiotic resistance

The way to human insulin

Classical production process for porcine insulin

Conversion of porcine insulin into H-insulin

Fermentative insulin production

Fermentative insulin production

Pro-insulin method

Fermentative production of H-insulin (simplified)

Historical development penicillin and insulin

Historical development penicillin and insulin

Pharmaceutical lactase:isolation & purification

Importance of product yield

Products of yellow biotechnology

Fermentation process for citric acid (simplified)

Alternative citric acid process: EFC

Alternative citric acid process: EDBD

Alternative citric acid process: extraction

Comparison chemical and bioprocesses

References

Glossary