Bindley Bioscience Center

Vision:Nurture interactive communication and interdisciplinary discovery with flexible laboratory project spaces and an open environment.

Mission:Provide high-level research capabilities with high-end instrumentation and scientific expertise for grant-sponsored projects, centers, and institutions.

www.purdue.edu/dp/bioscience ■ (765) 496-6147 ■ Bindley Bioscience Center, 1203 W. State St.

Transferring Life-Enhancing Technologies to Society

BiomolecularTechnologies

ComputationalLife Sciences

And Informatics

Bio-Nanotechnology

CytomicsAnd Imaging

Research Instrumentation DevelopmentBiosensors

Biomedical DevicesNew Technologies for Life Sciences

Precision Measurements

Developing Technologies

Impact● New Companies ● Cancer Diagnostics & Treatment● Improved Food Supply ● Bio-Fuels ● Bio-Defense

● Infectious Diseases ● Medical Devices ● New Drugs

Clinical & Corporate Partners PU Academic Units Discovery Park Centers

Core Research Facilities

www.purdue.edu/dp/bioscience ■ (765) 496-6147 ■ Bindley Bioscience Center, 1203 W. State St.

Bindley Bioscience Center Bindley Bioscience Center

Meeting grand challenges in plant, animal, and human diseases … discovering new technologies to improve health and prevent disease … enhancing early diagnosis …

Purdue Analytical Proteomics TeamMultidisciplinary collaborative team led by Purdue

Bindley Bioscience CenterOncological Sciences Center

e-Enterprise CenterCyber Center

Purdue Cancer CenterDepartment of Chemistry

Indiana University School of MedicineIndiana University (Bloomington)

Indiana & Purdue University at Indianapolis (IUPUI)Quadraspec, Inc

Safis-Solutions, LLCHoosier Oncology Group, LLC

Monarch Life Sciences (formerly INCAPS)Predictive Physiology and Medicine

Project:

Clinical Proteomic Technology Assessment for Cancer

$7 million grant from National Cancer Institute

GOAL:

Identify cancer biomarkers for more precise diagnoses and therapies tailored to individuals (personalized medicine).

Study proteins/protein components (biomarkers) and their relationships to cancers (specifically, breast and prostate cancers).

OUTCOMES:

Develop protocols and standardized techniques for all researchers to use to identify specific cancer biomarkers.

Create new technologies (systems for highly complex data collection and analysis) to find locations of these biomarkers.

www.purdue.edu/dp/bioscience ■ (765) 496-6147 ■ Bindley Bioscience Center, 1203 W. State St.

Discovery

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New scientific knowledge about biological systems … multidisciplinary problem-solving experiences for students and faculty … collaborative discovery and innovation student programs

78 Graduate students 9 Undergraduate students 4 High school students 17 Postdoctoral researchers15 Technical staff scientists14 BBC staff scientists 4 Visiting scholars93 Purdue faculty members

Project:

Physiological Bio-Sensing

Bindley Bioscience Center; Center for Environment; Birck Nanotechnology Center; Department of Agricultural & Biological Engineering; Weldon School of

Biomedical Engineering

GOAL: Develop nanoscale biosensors for use in biological applications

OUTCOMES:

Animal Production: Creating a hand-held device to assess food spoilage by monitoring animal muscle metabolism and breakdown on-site at food production plants. Crop Production: Developing biosensors to measure mineral nutrition and stress physiology of plants to assess growth, metabolism and ion transport.

Food Safety: Building biosensor instruments to monitor animal diseases and protect the food supply by detecting foodborne pathogens/toxins.

www.purdue.edu/dp/bioscience ■ (765) 496-6147 ■ Bindley Bioscience Center, 1203 W. State St.

Learning

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Innovation spun out for commercial development …corporate relationships … external collaborations … new companies formed

physics and chemistry combineto create efficient & comprehensive

medical testing device

Project:

BioCD Spinning Disc

21st Century grant from State of Indiana: Bindley Bioscience Center; Birck Nanotechnology Center; Department of Chemistry; Department of Physics

GOAL:

Create new concepts and tools in laboratory testing and diagnostics

OUTCOMES:

Develop a spinning disc (laser, detector, reader, spinner, optics, and signal processor) that holds immunoassays and delivers samples by placing tracks of different proteins the disc.

Samples are prepared and analyzed with a disc that can perform many different immunoassay measurements per second, producing reliable and effective quantitative analyses.

www.purdue.edu/dp/bioscience ■ (765) 496-6147 ■ Bindley Bioscience Center, 1203 W. State St.

Engagement

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