bile juice
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Bile is a thick digestive fluid, that is released by the liver
and stored in the gallbladder.
Bile is secreted upon eating into the duodenum.
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Color:
dark green to yellowish brown fluid
Volume:0.5 - l.0 L/day (depending on body size )
pH : 7.8-8.2
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Water (85%),
Biliary Solids (3 g%)
bile salts (1.8 g%), such as cholic, chenodeoxycholic,
deoxycholic, and lithocholic acid.
Mucus
Bile pigments (0.1 g%) e.g bilirubin glucuronid.
phospholipids (0.8 - 0.9g%).
Cholesterol (0.2 - 0.3 g%)
inorganic salts (0.7 g%) ,such as Na +, K +, HCO3-,Cl-
NO digestive enzymes
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Bile is an emulsifier, it helps to break down fats into
fatty acids, which can be taken into the body by the
digestive tract.
Bile juice reduces acidity of chyme.
Bile salts also act as bactericides ,it kills the germs andbacteria which are present in food.
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Cholelithiasis The movement of cholesterol from the liver into the bile
must be accompanied by the simultaneous secretion of
phospholipid and bile salts.
If this dual process is disrupted and more cholesterolenters the bile than it can be solubilized ,so cholesterol
may precipitate in the gallbladder, initiating the occurrence
of cholesterol gallstone disease- cholelithiasis .
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Gross malabsorption of bileacids from the intestine Obstruction of the biliary tract
Severe hepatic dysfunction,leading to decreased synthesis of
bile salts, or other abnormalitiesin bile production
Increased biliary cholesterol
excretion.
Cholelithiasis is caused by a
decrease of bile acids in thebile, which may result from:
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Jaundice It refers to the yellow color of skin, nailbeds, and sclerae
(whites of the eyes) caused by deposition of bilirubin.
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Newborn infants, particularly if premature, often accumulatebilirubin, because the activity of hepatic bilirubin glucuronyl
transferase is low at birth—it reaches adult levels in about four
weeks.
Elevated bilirubin,in excess of the binding capacity of albumin,
can diffuse into the basal ganglia and cause toxic
encephalopathy (kernicterus).
Newborns with significantly elevated bilirubin levels are treated
with blue fluorescent light which converts bilirubin to more
polar and, hence, water-soluble isomers.
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http://www.healthcentral.com/diet-exercise/h/bile-juice.html
Berne, RM and Levy, MN (2004), Physiology, 5th ed., St.
Louis, Mosby Yearbook
Champe, Pamela C. , Harvey, Richard A. , and Ferrier, Denise
R. (2008), Lippincott’s Illustrated Reviews:Biochemistry , 4th
ed. , Baltimore, Lippincott Williams & Wilkins
http://health.wikinut.com/img/18072lt_cc74sq5u/Jaundice-
Types