be careful about the text treatment of this 1. what is blocking? blocking is: a way to control for...

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Randomized Complete Block Designs Be careful about the text treatment of this 1

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Are Blocks Factors? Short answer: Sometimes. We may block on Gender in an experiment and in that case Gender is a factor. Long answer: Blocks are an indication that Experimental Units/Experimental Conditions vary from one run to the next. They are often nuisance parameters which we do not wish to confound with the Factors we are really interested in. 3

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Page 1: Be careful about the text treatment of this  1. What is Blocking? Blocking is: A way to control for a source of Variation in an Experiment. It may also

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Randomized Complete Block DesignsBe careful about the text treatment of this

Page 2: Be careful about the text treatment of this  1. What is Blocking? Blocking is: A way to control for a source of Variation in an Experiment. It may also

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What is Blocking?Blocking is:A way to control for a source of Variation

in an Experiment.It may also refer to a Replication of the

entire Experiment.It is usually included in the ANOVA Model

as a term.Some people handle it in “different” ways.

Page 3: Be careful about the text treatment of this  1. What is Blocking? Blocking is: A way to control for a source of Variation in an Experiment. It may also

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Are Blocks Factors?Short answer: Sometimes. We may block on

Gender in an experiment and in that case Gender is a factor.

Long answer: Blocks are an indication that Experimental Units/Experimental Conditions vary from one run to the next. They are often nuisance parameters which we do not wish to confound with the Factors we are really interested in.

Page 4: Be careful about the text treatment of this  1. What is Blocking? Blocking is: A way to control for a source of Variation in an Experiment. It may also

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ExamplesHospitals- Patient populations and facilities

vary.Farms- Soil type and Environment vary.Greenhouses- Environmental variation.Batch-Batches of material may vary from one

production run to the next.Basically any Replication of an entire

Experiment done at various times/places.

Page 5: Be careful about the text treatment of this  1. What is Blocking? Blocking is: A way to control for a source of Variation in an Experiment. It may also

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Blocking and InferenceBlocks Fixed- Inference is only to the

experimental units/conditions under which the Experiment is run, i.e. to these Blocks.

Blocks Random- Inference is to the experimental units/conditions for which these Blocks are representative (whatever that might reasonably be concluded to be).

Page 6: Be careful about the text treatment of this  1. What is Blocking? Blocking is: A way to control for a source of Variation in an Experiment. It may also

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Recall 5.21 with Day, Temperature and Pressure

We can think of the entire Experiment with Temperature and Pressure as a Factorial Experiment, with the entire Experiment replicated on two different Days. In this case Day is Block.

Page 7: Be careful about the text treatment of this  1. What is Blocking? Blocking is: A way to control for a source of Variation in an Experiment. It may also

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Consider Problem 5.21 with Day Fixed

Page 8: Be careful about the text treatment of this  1. What is Blocking? Blocking is: A way to control for a source of Variation in an Experiment. It may also

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Correct F-tests for Fixed Effects are by their Interaction with Day with Day Random

Page 9: Be careful about the text treatment of this  1. What is Blocking? Blocking is: A way to control for a source of Variation in an Experiment. It may also

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EMS Day Random and number of Days=d

2 2

2 2

2 2

2 2

2 2

2 2

3 3

3 3

3

3

P PD P

T TD T

PT PTD PT

PD PD

TD TD

PTD PTD

MS d

MS d

MS d

MS

MS

MS

Page 10: Be careful about the text treatment of this  1. What is Blocking? Blocking is: A way to control for a source of Variation in an Experiment. It may also

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Allocation of effort If fixed effects were marginally significant,

the EMS says to add Replications in more Blocks (Days).

Be careful since Replications has multiple meanings.

Page 11: Be careful about the text treatment of this  1. What is Blocking? Blocking is: A way to control for a source of Variation in an Experiment. It may also

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What happens if we include Day in the Model but not the Day Interaction terms? (Author suggests this)

Page 12: Be careful about the text treatment of this  1. What is Blocking? Blocking is: A way to control for a source of Variation in an Experiment. It may also

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Why was Interaction no longer significant?Answer: We inflated the Mean Square Error for

Temp*Pressure by pooling all of the Interaction terms into Error!

Moral of Story: When deleting terms from the model you can get misleading results.