bbr 2778 effective in relapsed, aggressive nhl

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Inpharma 1309 - 13 Oct 2001 BBR 2778 * shows efficacy in the treatment of relapsed, aggressive non-Hodgkin’s lymphoma (NHL), according to a preliminary analysis of study data presented at the annual meeting of the German Society of Hematology, held recently in Mannheim, Germany. Data were analysed from 27 patients with NHL who participated in the open-label study conducted in Germany and France. ** Patients were treated with 6 cycles of BBR 2778, administered intravenously at a dose of 85 mg/m 2 once weekly for 3 weeks. Three patients had a complete response and 3 had a partial response. BBR 2778 was generally well tolerated, with the most common adverse effect being neutropenia. * Novuspharma; phase II for non-Hodgkin’s lymphoma ** Most patients had advanced disease and had experienced relapse after prior chemotherapy. Novuspharma SpA. Novuspharma announces positive phase II results for BBR 2778 in non-Hodgkin’s lymphoma. Media Release : [2 pages], 1 Oct 2001. Available from: URL: http://www.novuspharma.com 800876260 1 Inpharma 13 Oct 2001 No. 1309 1173-8324/10/1309-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved

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Page 1: BBR 2778 effective in relapsed, aggressive NHL

Inpharma 1309 - 13 Oct 2001

■ BBR 2778* shows efficacy in the treatment ofrelapsed, aggressive non-Hodgkin’s lymphoma (NHL),according to a preliminary analysis of study datapresented at the annual meeting of the GermanSociety of Hematology, held recently in Mannheim,Germany. Data were analysed from 27 patients withNHL who participated in the open-label studyconducted in Germany and France.** Patients weretreated with ≤ 6 cycles of BBR 2778, administeredintravenously at a dose of 85 mg/m2 once weekly for 3weeks. Three patients had a complete response and 3had a partial response. BBR 2778 was generally welltolerated, with the most common adverse effect beingneutropenia.* Novuspharma; phase II for non-Hodgkin’s lymphoma** Most patients had advanced disease and had experiencedrelapse after prior chemotherapy.

Novuspharma SpA. Novuspharma announces positive phase II results for BBR2778 in non-Hodgkin’s lymphoma. Media Release : [2 pages], 1 Oct 2001.Available from: URL: http://www.novuspharma.com 800876260

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Inpharma 13 Oct 2001 No. 13091173-8324/10/1309-0001/$14.95 Adis © 2010 Springer International Publishing AG. All rights reserved