OverviewATMI LifeSciences is the source of bioprocess efficiency to its biopharmaceutical

customers, providing a broad range of innovative single-use mixing, storage, powder

transfer, packaging and bioreactor technology solutions that maximize product integrity

while optimizing manufacturing cost.

Integrity™ TK8 FilmIntegrity™ TK8 film represents the culmination of over a decade of experience in ultraclean

polymer film extrusion and bioprocess bag manufacture, and delivers performance to meet

or exceed the expectations of the most demanding users. TK8 embodies ATMI’s “one

film” philosophy, giving users access to a single film capable of serving in the full range of

bioprocess single-use bag applications, from storage vessels to mixing and bioreactor bags.

This approach can yield significant savings in validation effort, time and cost.

Integrity™ Single-Use Mixing Systems• Broadestrangeofflexible,single-usemixingsystems

• Mixingvolumesscalableupto2000L

• Containedsolid/liquidandliquid/liquidmixingsolutions

• Eliminatesnon-value-addedcleaning

• Eliminatescross-contaminationrisk

Integrity™Single-UseBioreactors• Scalable,ergonomicandmodularsystems

• Verylowmixingshearduetopaddle/spargemixingelement

• Carefullyadaptedforcultivationofsuspensionandadherentcellsatveryhighdensities

• Cube-shapedvesselmaintainscellintegrityandimprovesresults

• Controlofallprocessparametersensuringcustomizedcultureconditions

• NoneedforCIP/SIP

• Avoidcross-contaminationrisks

atmi lifesciences

Integrity™ Bioprocess SolutionsLeading the Way in Advanced Single-Use Technologies

Integrity™ BioprocessSolutions

Integrity™Single-UseLiquidStorageBioprocessVessels• Availablein2-Dor3-Dbagconfigurationswithsizesfrom1Lto3,000L.Standardor custom connectivity options.• ConstructedwithIntegrityTK8“universal”bioprocessfilm.ManufacturedunderISO Class5cleanroomconditions.• Suitableforalltypicalbioprocessliquidstorageapplications.

Integrity™Single-UsePowderTransferVessels• Flexible,transparent,funnel-shapedbagswithtri-clampinterfacesforbroadprocess compatibility.• AntistaticUSPClassVI/ADCFfilmforsafe,containedpowderhandlingandhigh material recovery.• Suitableforpowderstorageandtransferapplicationssuchasmedia,buffers,and pharmaceutical ingredients.

Newform™Ultraclean,FlexiblePackaging• Cleansteam™ steam-sterilizable pouches for packaging of stoppers, vials and other cleanroom devices • Steam-autoclave,EtO,VHPandgammasterilizable• Ultracleanmedicalgradepolyethylenebagsforpackagingofmedicaldevices, IV-solutionsandAPI’s

About ATMI LifeSciencesAdvancedTechnologyMaterialsInc.(NASDAQ:ATMI)istheworld’slargestmanufacturerofultra-cleanflexiblecontainersandpackaging.Itsexperienceinthesemiconductorandlifescienceindustrieshasdriventhecompanytoachievehighstandardsofproductqualityand cleanliness. ATMI LifeSciences proprietary films are manufactured in its own facilities andmeetapplicableindustrystandards.EverystepofthebagmanufacturingandassemblyprocessisperformedinacontrolledenvironmentunderISOClass5cleanroomconditions.ContactyourlocalATMILifeSciencesrepresentativetodiscussyourparticularprocessneeds, and how ATMI can contribute to your success.

ATMI,10851LouisianaAvenueSouth,Bloomington,MN55438USA,800.966.6698or952.942.0855• ATMI,Reugelstraat2,3320Hoegaarden,Belgium,+32.16.76.80.70 www.atmi-lifesciences.com • info@atmi-lifesciences.com ©2010ATMI,Inc.Allrightsreserved.ATMI,theATMIlogo,Cleansteam,IntegrityandNewformaretrademarksorregisteredtrademarksofAdvancedTechnologyMaterials,Inc. in the U.S., other countries, or both.

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ATMI LifeSciences The Source of Bioprocess Efficiency™