arteries serve as hydraulic filter reduced compliance is a manifestation of: ↑ collagen content...
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Arterial System and Blood Pressure
Arterial System and Blood Pressure
Arteries serve as hydraulic filter
Arterial System and Blood Pressure
Arterial System and Blood Pressure
Arteries Are Compliant Tubes
Reduced compliance is a manifestation of:• ↑Collagen content• ↓Elastin content
Slop = Compliance
Arterial System and Blood Pressure
Factors that determined Arterial Blood Pressure
Mean Arterial Pressure(MAP)
3
P - P P P ds
__
da
Arterial System and Blood Pressure
Change in complianceChange In Stroke Volume
Arterial System and Blood Pressure
Arterial pulse pressure
Arterial System and Blood Pressure
Arterial pulse pressure
Why Pulse pressure change itself
shape along the artery tree? Likely;
1.Decreased compliance of distal
arteries
2.Reflective waves, particularly from
arterial branch point
Arterial System and Blood PressurePulse Wave
Speed: Aorta 3-5 m/s Large arteries 7 –
10 m/s Small arteries 15 -
35 m/s
Arterial System and Blood Pressure
Effects of Pressure on Vascular Resistance and Tissue Blood Flow
The reasons:1. Increases the force that pushes blood2. Distends the vessels at the same time
Arterial System and Blood Pressure
Changes in systolic, diastolic, and mean arterial pressures with age
Veins and Their Functions
• Right Atrial Pressure (Central Venous Pressure)Regulated by a balance between
(1) The ability of the heart to pump blood out of the right atrium and ventricle into the lungs
(2) The tendency for blood to flow from the peripheral veins into the right atrium.
Venous Pressures:
Veins and Their Functions
• Peripheral Venous Pressures
Venous Pressures:
Veins and Their Functions
Spleen (as much as 100 ml)
Liver (several hundred ml)
large abdominal veins (as much as
300)
Venous plexus beneath the skin
(several hundred ml)
Heart (~ 50 -100 ml)
Lungs (~ 100 -200 ml)
Specific Blood ReservoirsReference point for circulatory pressure