arrhythmias after cardiac surgery
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POST CARDIAC SURGERY ARRHYTHMIAS
30/4/11
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Post cardiac surgery arrhythmias
Potential causes and precipitating factors
Myocardial ischemia or infarctionHemodynamic instability
Electrolyte abnormalitiesa) Hypokalemia, b) Hypomagnesemia
Metabolic disturbancesa) Acidosis, b) Alkalosis, c) Hypoxemia
Drugsa) Sympathomimetics, b) Antiarrhythmics, c) Anesthetic
Reperfusion effectTissue trauma or inflammation, indwelling cathetersIncrease in catecholamines
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Common arrhythmias after cardiac surgery
1. Sinus tachycardia
2. Ventricular premature complexes
3. Ventricular tachycardia
4. Atrial fibrillation, atrial flutter
5. AV & IV conduction block
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Sinus tachycardia
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Sinus tachycardia
Causes
Pain
Anxiety Low cardiac output
Anemia
Fever
Beta blocker withdrawal
Managed by treating the underlying cause
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Ventricular premature complexes
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VPC ² couplet
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VPC ² complex form
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VPC ² complex form
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NSVT
NSVT
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Ventricular arrhythmias
Management of PVC·s and NSVT
y Simple PVCs usually do not require Rx
y If frequent and symptomatic can besuppressed with beta blockers or AA
y No role for prophylactic lidocaine
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MAN AGEMENT OF POST CABG VT/VF
Post CABGSust. Vent. Tachyarryth.
Ventricular Fibrillation
Defib / IV Amiodarone
Identify/Tr eat ppt factors
No further AA therapy
Recurr enceUse other IV drugs
EPS guidedAA therapy
UnsuccessfulConsider ICD therapy
SuccessfulContinue the drugs
Ventricular tachycar dia
Unstable
Use V-Fib Protocol
Stable
IV Amiodarone
Tr eat Ppt factors
Recurr ence
Use V Fib recurr. protocol
No r ecurr ence
No further therapy
No Recurrence
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Atrial fibrillation
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Atrial flutter
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Postoperative AF may occur in...
40% of patients undergoingCABG
35% to 40% after valvular surgery
60% after combinedCABG and valve surgery
11% to 24% after cardiac transplantation
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Clinical implications
Increased incidence of postoperativecomplications : hypotension
MI / CHF
CVA/ decline in Mini-Mental State Examination score
Respiratory failure
Renal dysfunction
Infections longer length of hospital stay
lower in-hospital and long term survival
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Pre-operative risk factors
Advanced age
Male gender
Hypertension
Previous AF History of cardiac surgery
CHF
COPD
RCA disease
Peripheral vascular disease
Valvular heart disease
BSA
LVH
Left atrial enlargement
Electrocardiographic
features-P wave durationon SAECG
Renal failure
Moderate or severe aorticatherosclerosis
Withdrawal of beta-blockeror ACEI/ use of digoxin
Obesity and metabolicsyndrome
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Intraoperative risk factors
Aortic cross-clamp time
Bicaval cannulation
Pulmonary vein venting Lack of use of topical ice slush
Type of surgery
Need of perioperative IABP
CPB time
CPB inclusive of cardioplegic arrest
Systemic hypothermia
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Post-operative risk factors
Respiratory compromise
Red cell transfusion
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Day of onset of atrial fibrillation after
CABG
0
2
4
6
Pts
1 2 3 4 5
POST-OPERATIVE DAY
Klein et al.Am Ht Jn, 1995;129:895 - 901
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L ength of stay in hospital after postopatrialarrhythmias
0
2
4
6
8
10
12
D a y s
ICU WARD
Without atrialarrythmia
With atrial arrythmia
Cr eswell et al, Ann. of Thoac. Surg, 1993;56:539 -
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Prevention of post-operative AF
Beta blockers should be administered peri-operatively, 1 to 2 weeks pre op, in patientswithout contraindications until the day of
surgery (Class I A) Preoperative administration of oral
amiodarone,6days prior, for patients who havecontraindications to therapy with beta-blockers
and high risk of AF (PAPABEAR) (Class IIa A) Low -dose sotalol should be considered in
patients who are not candidates for traditionalbeta-blocker (Class IIb A)
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Prevention of post-operative AF
Bi-atrial overdrive pacing has been shown to
be effective in preventing postoperative
AF (IIb A) Corticosteroids may decrease the incidence
of postoperative AF by reducing the
inflammatory response after surgery (IIb B)
All patients without contraindications for
statin therapy should receive it ( 40mg/d, 7
days prior) beforeCABG surgery(ARMYDA 3)
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Prevention of post-operative AF
prophylactic magnesium therapy is not
routinely recommended
no indication for using digitalis / CCB for theprevention of postoperative AF.
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Prevention of post-operative AF
The AmericanCollege of Chest Physicians
guidelines recommend the following possible
intraoperative preventive strategies :
mild hypothermia (for example, 34C)
the use of posterior pericardiotomy
heparin-coatedCPB circuits
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Prevention of post-operative AF
Off-pumpCABG Vs conventional CABG with
CPB:
Contradictory evidence concerning the advantageof OPCAB in reducing the rate of postoperativeAF
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Management
Spontaneous conversion of AF may occur
within 2 hours in 15% to 30% of patients and
within 24 hours in 25% to 80% of patients.
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Cardioversion
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Direct current cardioversion
Biphasic external defibrillators: lower energy
requirements and greater efficacy
Anteroposterior electrode placement is moreeffective
Synchronized with the QRS complex
High energy is required for AFcardioversion - atleast 120 J , biphasic
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Conduction Disturbances
y Transient conduction disturbances can occur in4% to 58% of patients afterCABG
y Incidence of isolated AV block is low afterCABGbut may be higher after associated valve surgery
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Conduction disturbances
First Degree AV block
y Most commonly due to:
y fibrosis of AV node
y toxicity of medications
such as beta blockers orcalcium channel blockers
y edema of AV node region
after mitral and aorticvalve replacement
y No specific therapy isusually needed
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Conduction disturbances
Second-Degree AV block
y MobitzType I and Type II blocksare common after valve
replacement surgery
y Drug effect or toxicity should beexcluded as potential causes
y Temporary pacing may beneeded depending on degree of AV block and HR as well asadequacy of lower escaperhythm
Mobitz type I
Mobitz type II
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Conduction disturbances
Complete AV block
y May be secondary tocardioplegia washout duringimmediate postoperative period
y Consequence of antiarrhythmicdrug therapy
y May be seen after valve
replacement secondary totrauma of surgical manipulationin the area of AV node or bundleof HIS
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Conduction disturbances:
Complete AV block- Treatment:y Discontinuation of all potentially offending
drugs
y Therapy depends on underlying heart rateand adequacy of underlying ventricularescape rhythm
y Treated with temporary pacing , via
epicardial pacing wires
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Conduction disturbances
Complete AV blocky Factors which predict low likelihood of
recovery includey
calcified Aortic valvey delayed appearance of AV block
y significant preop conduction defect
y In absence of excessive calcification, and inpresence of a narrow complex escape rhythm
with a good heart rate, PPM placement maybe delayed up to 2 wks
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Summary
AF is the most significant arrhythmia that occurs after cardiacsurgery.
It is associated with an increase in morbidity, length of hospital
stay, and mortality.
Patients who are at higher risk of postoperative AF should receiveprophylactic treatment.
AF usually resolves spontaneously after heart rate is controlled
Patients with AF of more than 48 hours should receiveantithrombotic therapy for thromboembolism prevention.
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Thank yo