antimicrobial resistance (amr): a global and multisectoral issue of concern to all

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ANTIMICROBIAL RESISTANCE (AMR) A GLOBAL AND MULTISECTORAL ISSUE OF CONCERN TO ALL

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This presentation addresses the growing global threat of AMR, its known and potential consequences for public health, agriculture and food security and FAO’s role in addressing the food and agriculture dimensions of the problem. ©FAO/Patrick Otto

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Page 1: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

ANTIMICROBIAL RESISTANCE (AMR)

A GLOBAL AND MULTISECTORAL ISSUE

OF CONCERN TO ALL

A GLOBAL AND MULTISECTORAL ISSUE

OF CONCERN TO ALL

Page 2: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

One of the most important discoveries of the 20th century

Sir Alexander Fleming discovered

ANTIBIOTICS

1928 1928

Page 3: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

One of the most important discoveries of the 20th century

Sir Alexander Fleming discovered

ANTIBIOTICS

1928 1928

Page 4: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

THE INTRODUCTION OF ANTIBIOTICS RAPIDLY EXTENDED LIFE EXPECTANCYTHE INTRODUCTION OF ANTIBIOTICS RAPIDLY EXTENDED LIFE EXPECTANCY

Transformation of Life and Livelihoods

1945 = 50 years

Today = 80 years (developed countries)Increase of 30 years

within 50 years

Page 5: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

THE INTRODUCTION OF ANTIBIOTICS RAPIDLY EXTENDED LIFE EXPECTANCYTHE INTRODUCTION OF ANTIBIOTICS RAPIDLY EXTENDED LIFE EXPECTANCY

Transformation of Life and Livelihoods

1945 = 50 years

Today = 80 years (developed countries)Increase of 30 years

within 50 years

Page 6: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

Transformation of Life and Livelihoods

THE INTRODUCTION OF ANTIBIOTICS RAPIDLY IMPROVED...THE INTRODUCTION OF ANTIBIOTICS RAPIDLY IMPROVED...

PRODUCTION INCOME LIVELIHOOD

Page 7: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

Transformation of Life and Livelihoods

THE INTRODUCTION OF ANTIBIOTICS RAPIDLY IMPROVED...THE INTRODUCTION OF ANTIBIOTICS RAPIDLY IMPROVED...

PRODUCTION INCOME LIVELIHOOD

THE INTRODUCTION OF ANTIBIOTICS RAPIDLY IMPROVED...

Page 8: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

There is the danger, that the ignorant man may easily underdose himself and by exposing his microbes to non-lethal quantities of the drug make them resistant.

Alexander Fleming

Transformation of Life and Livelihoods

Page 9: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

Today, Resistance is emerging and spreading faster than new drugs are being developed

There is the danger, that the ignorant man may easily underdose himself and by exposing his microbes to non-lethal quantities of the drug make them resistant.

Alexander Fleming

Transformation of Life and Livelihoods

Page 10: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

Costs and Consequences

INAPPROPRIATE USE hasa negative impact on:INAPPROPRIATE USE hasa negative impact on:

HUMAN HEALTHand PRODUCTION

LIVELIHOOD

ECONOMY

Page 11: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

Costs and Consequences

INAPPROPRIATE USE hasa negative impact on:INAPPROPRIATE USE hasa negative impact on:

HUMAN HEALTHand PRODUCTION

LIVELIHOOD

ECONOMY

Page 12: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

Socio-economic consequences

Page 13: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

Anti-Microbial Resistance

Deaths/year• 25,000 - EU• 500,000 - Global

(est.)

USA - health care costs• $ 20 bn/yr

Lost productivity • USA $ 35

billion/yr• EU € 1.5

billion/yr

Socio-economic consequences

Page 14: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

MAKE AMR A MORE COMPLEX CHALLENGEA multisectoral and Global problem

ENVIRORMENTFOOD

HUMAN ANIMALS

Page 15: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

MAKE AMR A MORE COMPLEX CHALLENGE

ENVIRORMENTFOOD

HUMAN ANIMALS

Page 16: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

ENVIRORMENT

HUMAN

AN

IMA

LSFOO

D

Page 17: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

GROWTH THE DEMAND

NOW

Page 18: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

GROWTH THE DEMAND

2050+70%

2050+70%

NOW

Page 19: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

RESISTANCE

LIVESTOCK PRODUCTS LIVESTOCK PRODUCTS

PRODUCTIONPRODUCTION

ANTIMICROBIALSANTIMICROBIALS

PRODUCTION AND DEMAND TRENDS

DEMANDDEMAND

Page 20: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

RESISTANCE

LIVESTOCK PRODUCTS LIVESTOCK PRODUCTS

PRODUCTIONPRODUCTION

ANTIMICROBIALSANTIMICROBIALS

PRODUCTION AND DEMAND TRENDS

DEMANDDEMAND

Page 21: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

AMR DOES NOT RESPECT

GEOGRAPHICAL, SPECIES

OR ECOLOGICAL BORDERS

GLOBALIZATION: TRADE, TRAVEL, TRANSPORTATION...

Page 22: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

AMR DOES NOT RESPECT

GEOGRAPHICAL, SPECIES

OR ECOLOGICAL BORDERS

GLOBALIZATION: TRADE, TRAVEL, TRANSPORTATION...

Page 23: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

HOW FAO CAN SUPPORT MEMBERS COUNTRIES

Policy

Regulatory support

AMR detection, monitoring of trends - laboratory capacity support

Standards setting – Codex, OIE

Guidance

Page 24: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

HOW FAO CAN SUPPORT MEMBERS COUNTRIES

Policy

Regulatory support

AMR detection, monitoring of trends - laboratory capacity support

Standards setting – Codex, OIE

Guidance

Page 25: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

HOW FAO CAN SUPPORT PRODUCERS

GOOD PRACTICES

ANIMAL HEALTH,

HUSBANDRY,

BIOSECURITY

MEASURES

PARTICIPATION IN TRADE

ACCESS TO MARKETS

STANDARDS AND REQUIREMENTS

VETERINARY DRUGS

Page 26: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

HOW FAO CAN SUPPORT PRODUCERS

GOOD PRACTICES

ANIMAL HEALTH,

HUSBANDRY,

BIOSECURITY

MEASURES

PROMOTE

IMPROVE

PARTICIPATION IN TRADE

ACCESS TO MARKETS

STANDARDS AND REQUIREMENTS

VETERINARY DRUGS

REDUCE

Page 27: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

AVAILABLE KNOWLEDGE & GAPS

ANIMALS HUMANS

ZOONOTIC

ENVIRONMENT

???

?

?

Page 28: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

GLOBAL PARTNERSHIPS

Global Action Plan for AMR Global Health Security Agenda  FAO/WHO/OIE Tripartite need holistic One Health approach addressing AMR in all sectors (human, animal and environment) and all stages of the continuum from food production to consumption EU, World Bank, OECD etc

Private Sector

Page 29: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

GLOBAL PARTNERSHIPS

Global Action Plan for AMR Global Health Security Agenda  FAO/WHO/OIE Tripartite need holistic One Health approach addressing AMR in all sectors (human, animal and environment) and all stages of the continuum from food production to consumption EU, World Bank, OECD etc

Private Sector

Page 30: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

ANTIMICROBIAL RESISTANCE (AMR)

?A PRE- OR POSTANTIBIOTICS ERA

?A PRE- OR POSTANTIBIOTICS ERA

Page 31: Antimicrobial Resistance (AMR): A global and Multisectoral issue of concern to all

ANTIMICROBIAL RESISTANCE (AMR)

THANK YOU THANK YOU