anti- nic vaccine
TRANSCRIPT
William Shakespeare George Harrison
Walt Disney George Washington
PRESENTED BY:AFRIN SULTANA CHOWDHURYSADEKA BANU RIYAMD. ARIFUL ISLAM
AntiNicAnti-Nicotine Vaccine
for Smoking Cessation
Kill the Silent Killer Silently
Mission & Vision
Mission: To provide sustainable solution of the nicotine causing health risks to the smokers.
Vision: To catch the current demand and become the market leader in both domestic and regional level in next 10 years
Management
CEO: Afrin Sultana Chowdhury Head of Research: Md. Ariful Islam Head of Marketing: Sadeka Banu Riya
AntiNic• AntiNic is a vaccine, creates antibodies against nicotine• Contains Adeno Associated Viruses (AAV) that consist of
the genetic sequence, engineered from a nicotine antibody
• Intramuscular injection genetically modifies patient’s body to churn out nicotine antibodies
• Provide a lifetime nicotine antibody "factory" in the body. • The antibodies then work by targeting the nicotine cells
within seconds of exposure and preventing them from reaching receptors in the brain
Why Using AAV ??Wide host-rangeLack of pathogenicityAble to transduce a wide variety of cellsAllows permanent Genetic Implantations to
occurVirus encoded genes have been removed
Comparative Analysis
Current Drugs/ Treatments• Huge side-effects• Effectively is very less• Safety problem• Less available• Resistance• Age-specific (18- 55)• High cost• Long time course
AntiNic Vaccine• Very few side-effects• Highly effective• 100% safe
• No resistance• Wide age range (15- Higher)• Low cost• Inject once
Methods
• Use of Adeno virus for the replication of AAV• Transfection with human embryonic kidney cells• After the transfection, the cells are harvested and
purified using ultracentrifugation• Intramuscular injection of vaccine• Viruses insert genetic material at a specific site on
chromosome 19• Gene expression- monoclonal antibody production• Clinical benefits
Smoker’s Rate worldwide
Survey for Smoking TreatmentWorldwide Survey
In Bangladesh No Current Treatment is Available !!
SWOT Analysis
• New entry• Increase in
production and Labour cost
• Bio product• Technology
development and innovation
• Expensive• A few side
effects• Public
concern
• Target specific
• Non pathogenic
• AAV vectors used in gene therapy
Strong points
Weak points
ThreatsOpportunities
Market Attractiveness
• Huge demand worldwide• 50% of the patients are not responsive enough
to current treatments• Number of target patients in Bangladesh• Reduce the risks of vital diseases • Very little side-effect• Cost effective
Total seed fundingITEMS PROPOSED
Land Fixed Asset
Building Established
Research 5 m
Machineries and Equipment Established
Vehicle Established
Wages and labor cost .4 mUtility .3 mRepair/ Maintenance .7 mRaw Material 5 mOther .6 mTOTAL 12 m Taka
AntiNic Timeline
AntiNicin Lab Pilot Project FDA Review High Level
Production
Tk. 90 Lakh
12 mon
Tk. 40 Lakh Tk. 60 Lakh
12 mon 18 mon 12 mon
Market
Research & Development
• Research to revert a wide range of pathologies for more successful gene transfer without major side effects
• Research for new product for drug addiction• Research for eliminating smoking addiction
Target Audience & Customer
All the illiterate person who have at least basic knowledge on biological science and technology
Target Customer
Target Audience
• Middle class• Upper middle class• Upper class
Price
Target Market
2014 2017 2020 Bangladesh India, China, Thailand Europe
Promotion
Our Promoters
Dr. Mohit Kamal
Drug addiction treatment Specialist
and Psychiatrist
Ferdouse
Sources: http://archives.drugabuse.gov/NIDA_Notes/NNVol20N2/Site.html http://www.ncbi.nlm.nih.gov/pmc/articles/PMC155067/ http://www.cbsnews.com/news/vaccine-stops-nicotine-from-reaching-the-brain-may-prevent-addiction/