annual report 2008 - cragenomica.es · environmental stress, in both biotic (attack by pathogens)...

ANNUAL REPORT

2008craG

2

3. O

ur d

epa

rtm

ents

0. I

ndex

contents1. Brief about the activity in the center 2008 by the Director.

2. CRAG

Direction Board•Scientific Advisory Board (SAB)•CRAG Structure•

3. Our departments: A Multidisciplinary Scientific research.

Brief about research in the department:•GM Department: •

Plant genomics and biotechnologyPlant metabolism and metabolic engineeringPlant responses to biotic and environmental stressesSignal transduction and plant development

GV Department: •Crop genomics Sub-programme Plant in Vitro Culture

GA Department•Core Facilities•

4. Scientific Activity

Research projects •Scientific output: papers, books, doctoral theses •

5. Human Resources

6. Financial Resources

7. Appendix I: Projects & Contracts

8. Appendix II: Papers, Books & Doctoral theses

4

3. O

ur d

epa

rtm

ents

1. Brief about the activity in the center 2008 by the Director

5

1. B

rief

ab

out t

he a

ctiv

ity in

the

cen

ter

200

8 by

the

Direc

tor

A Centre under constructionDuring 2008 the building that will host the Centre for Re-search in Agricultural Genomics, CSIC-IRTA-UAB has deve-loped its structure in the Bellaterra Campus of the Autono-mous University of Barcelona. This year the University has become a full component of the public Consortium that was formed by CSIC and IRTA in 2003. During these years the CRAG has built up its own administrative structure and its own culture. This is the first time that CRAG publishes its annual report and a full web site is already in the net. Those are essential steps to make the Centre visible for the general public and for the scientific community.

The Centre for Research in Agricultural Genomics is in this way developing its activity that is devoted to research in the molecular basis of essential characters of plants and farm animals. The Centre is trying to develop basic research in molecular mechanisms involved in plant development and defence and to develop and apply molecular methods that

can be useful for breeding of plants and farm animals. This is the reason that our groups are studying Arabidopsis and peach, rice and melon or tomato and pig. This is also the reason that during 2008 we have invested in new infras-tructures that are allowing us to have access to the tools of massive genetic analysis. These include genotyping pla-tforms, microarray analysis and massive sequencing.

The CRAG is proud of the trust that our founder institutions, CSIC, IRTA and UAB have put in our Centre and acknowled-ges the funding provided by The General Direction of Re-search of the Department of Innovation, Universities and Industries of the Generalitat de Catalunya. When all our groups will be together in the new building in Bellaterra at the beginning of 2010 a new era will start for CRAG that will put its activity with the goals of increasing our knowledge of biological systems that are essential for the future of our society in a complex and changing environment.

6

3. O

ur d

epa

rtm

ents

2. CRAG

7

2. C

RA

G

Direction BoardD. Rafael Rodrigo Montero, Presidente del CSIC, y Presidente del Consejo de Dirección.

D. Josep Mª Monfort Bolivar, Director general del IRTA y Vicepresidente del Consejo de Dirección.

D. Francisco Montero de Espinosa Freijo, Vicepresidente de Organización y Relaciones Institucionales del CSIC.

D. Lluis Calvo Calvo, Delegado del CSIC en Cataluña.

D. Ignacio Fita Rodríguez, Director del IBMB.

D. Agustí Fonts Cavestany, Subdirector del IRTA.

D. Pere Arús Gorina, Director científico del IRTA.

D. Joan Roca Acín, Director General de Investigación del DIUE.

Dña. Ana Ripoll Aracil, Rectora de la UAB.

D. Jordi Marquet Cortes, Vicerrector de Proyectos estratégicos de la Universidad Autónoma de Barcelona (U.A.B.).

D. Francesc Godia Casablancas, Comisionat de la Rectora per a Biotecnología i Biomedicina.

Scientific Advisory Board (SAB)D. José Pio Beltran, Profesor de Investigación del CSIC, Instituto de Biología Molecular y Celular de Plantas.

Dña. Cathie Martin, Investigadora John Innes del Norwich Center, England.

D. Daniel Zamir, Profesor de la Universidad Hebrea de Jerusalem, Facultad de Agricultura, Israel.

D. Michael Delseny, Director de Investigación del CNRS, Laboratorio de Genoma y desarrollo de Plantas, Universidad de Perpignan, Francia.

D. Uwe Sonnewald, Profesor de Bioquímica del Dpto. de Biología de la Universidad de Erlangen, Alemania.

CRAG Structure

8

3. O

ur d

epa

rtm

ents

3. Our departments A Multidisciplinary Scientific research

9

3. O

ur d

epa

rtm

ents

Molecular genomics departmentThe scientific activity of the Department aims to impro-ve the knowledge and understanding of the structure, function and dynamics of the plant genome, and of its in-terplay with the physiology, biochemistry, growth and de-velopment, and stress and pathogen responses of plants.

Ongoing research projects in the Department encompass many different aspect of plant biology. An area of research is the structure of the genomes of plants, including ge-nome sequencing projects, the characterization of mobile elements, and the identification and characterization of plant genes, with a special emphasis on genes of agro-nomic interest. There are also projects focused on the re-gulation of gene expression associated with processes of plant development and reproduction (regulation by light and photoperiod, the biological clock, flower develop-ment, root and vascular tissue development, embryogene-sis, fruit maturation), as well as on the plant responses to environmental stress, in both biotic (attack by pathogens) and abiotic (drought, salt) situations. In addition, plant biochemistry and metabolism is also an active area of re-search, including projects on protein synthesis, transport and storage, cell wall and lignin biosynthesis, and meta-bolic engineering.

1. Plant genomics and biotechnologyResearch in plant biology has been fundamentally chan-ged over the past decade, as a result of revolutionary breakthroughs in genome sequencing of plants, including Arabidopsis thaliana, rice, poplar, papaya, and soon maize and many other plants and crops. Plant scientists have made excellent use of the advances in genomics research, on model species and on crops, to explain basic biological principles as well as in subsequent applications to crop improvement.

The general focus of this research line is the characteriza-tion and understanding of plant genomes (both at a struc-

tural and functional level), and the development of plant biotechnology, genomics, and related life science techno-logies to harness the potential of plant genomes for crop improvement and to foster understanding in plant biology. Genome sciences are multidisciplinary in nature, and so is this research line, both in the technologies as well as in the plants used.

This research line encompasses the work of two CSIC groups, led by Profs. Puigdomenech and Ludevid, respec-tively, as well as that of the group of ICREA Research Prof. Riechmann, whom recently joined the CRAG. These groups are working on a diverse range of topics, which include (as explained in detail in the Extended Description): the sequencing of the melon genome and the development of tools useful to identify genes interesting for breeding of the species; the use of plants as biofactories; and the stu-dy of plant gene regulatory networks using genomic tech-nologies. The work by these groups intersects with those of other groups and lines at the CRAG, both at the scientific and at the technical level. In addition, genomics research is enabled by, and critically dependent on, ever evolving

10

3. O

ur d

epa

rtm

ents

high-throughput technologies. In the CRAG, those techno-logies are being centralized on the Genomic Services unit. Thus, those services should be considered in the context of this research line, and vice versa. The general aim of this research line is the characterization and understanding of plant genomes (both at a structural and functional level), and the development of plant biote-chnology, genomics, and related life science technologies to harness the potential of plant genomes for crop impro-vement and to foster understanding in plant biology.

Research in plant biology has been fundamentally chan-ged over the past decade, as a result of revolutionary breakthroughs in genome sequencing of plants, including Arabidopsis thaliana, rice, poplar, papaya, and soon maize and many other plants and crops. Plant scientists have made excellent use of the advances in genomics research, on model species and on crops, to explain basic biological principles as well as in subsequent applications to crop improvement.

1.1. Melon Genomics. Pere Puigdomènech Rosell

1.2. Gene regulatory networks in plant development. José Luis Riechmann 1.3. Targeting and production of proteins in plants. Dolors Ludevid Mújica

2. Plant metabolism and metabolic engineeringThe research line “Plant metabolism and metabolic enginee-ring” addresses the study of the regulation and organization of target metabolic pathways using biochemical, molecular and genetic strategies with different plant model systems (including Arabidopsis, tomato, tobacco, and maize). We aim to generate fundamental knowledge of how plants con-trol their primary and secondary metabolism that could be useful to eventually improve the quality of plant products.

2.1. Biosynthesis of plastidial isoprenoid precursors and carotenoid metabolic engineering. Manuel Rodríguez Concepción

2.2. Maize Cell-Wall Biotech: Bioenergy and Digestibility of Lignocellulosic Biomass. David Caparrós Ruiz Joan Rigau

2.3. Development of the maize scutellum. Carlos M. Vicient Sánchez

3. Plant responses to biotic and enviromental stressesThe general objective of the line is to understand the res-ponses of plants to the environment and to stresses caused by abiotic and biotic factors. This main objective includes several specific goals related to aspects of plant responses, such as understanding the sensing mechanisms implicated, the processes of recognition, the transduction of signals and the characterization of the different elements of the reactions. The intended outcome is to provide knowledge to increase the potential productivity of crops by reducing the negative impact caused in plants by the environment and the different stresses.

11

3. O

ur d

epa

rtm

ents

The main goal of the participant research groups is to bet-ter understand how plants respond to stress conditions, either caused by the environment or by the presence of biotic agents such as pathogens or pests. Thus, different aspects are being contemplated, including: basic studies with plant pathogens and/or stress condtitions, analysis of the sensing systems within the plant, initiation and main-tenance of the responses, signal transduction pathways, elements of the responses, and so on. The final goal will be to apply such knowledges to manipulate the responses, searching the benefit for the plant organisms, i.e. obtain organisms better adapted to survive and be productive in changing environmental situations of diverse agresiveness, and/or under the attack of different pathogenic agents.

3.1. Abiotic Stress: Signal transduction by absicic acid. Montserrat Pagès Torrens Adela Goday Baylina Victoria Lumbreras Ruiz 3.2. Plant response to environmental stress. Blanca San Segundo

Production of antimicrobials peptides in plants.María Coca

Identification and study of the mode of action of Antimicrobial Peptides.Belén López García

3.3. Role of plastidial transglutaminase-TGZ, in thylakoid membranes and photosynthesis related processes. Josep María Torné Cubiro Mireia Santos Lozano

3.4. Light control of plant development. Jaume Martínez-García

3.5. Plant viruses control and mechanisms of transmission. Juan José López-Moya 3.6. Plant molecular biochemistry. Luisa María Lois

4. Signal transduction and plant developmentThe research line is focused on understanding signalling pathways and mechanisms governing plant cell growth and development. To this end, the different research groups are interested in a diverse range of topics including the cellular and molecular determinants of plant develo-pment and the regulatory networks and factors affecting plant physiology and genome silencing and stability. The experimental designs involve a number of different geno-mic, genetic, biochemical and molecular strategies using

12

3. O

ur d

epa

rtm

ents

different model systems including tobacco, potato and maize plants as well as the small dicotyledonous species Arabidopsis thaliana. Specifically, the research line invol-ves studies on the circadian clock, light perception and photoperiodic pathways, programmed cell death, regula-tion of gene expression through non-coding and repetitive sequences, hormone signalling and floral and vascular and embryo development.

The main goal is to understand how plants integrate en-dogenous and exogenous cues to regulate growth and de-velopment. To that end, different scientific, experimental and methodological approaches are combined in order to get a complete view of the mechanisms regulating the plant life cycle. This multidisciplinary approach aims to the coordination of the different research lines, facilitating the collaboration among the groups, sharing the results and resources and promoting top-quality research programs. A long term goal of this research line would include the

translation of all the basic information obtained with the experimental model systems into research that can be applied to plants of agronomic interest.

4.1. Molecular Mechanisms of circadian clock function in Arabidopsis thaliana. Paloma Más Martínez

4.2. Control, Evolution and impact on genes of plants transposons. Josep M. Casacuberta Suñer 4.3. Long-distance signalling in the control of tuberization and flowering. Paula Suárez López 4.4. Dark and Light signaling in Arabidopsis. Elena Monte Collado

4.5. Floral development in Arabidopsis: role of the Tempranillo genes. Soraya Pelaz 4.6. Laboratory of Plant Vascular Development. Ana Caño Delgado

Plant Genetics DepartmentThe Plant Genetics Department in CRAG (IRTA Genomics and Biotechnology Programme) performs research activi-ties in plant genomics and in vitro culture in vegetable and fruit crops.

13

3. O

ur d

epa

rtm

ents

The main research activities of the Plant Genetics De-partment are:

Use of molecular markers for cultivar identification •and marker assisted selection in vegetable crops, fruit trees and ornamental species.Plant genomics of vegetable and fruit crops.•Use of in vitro culture techniques to obtain diploha-•ploid lines in vegetable and ornamental plants.Genetic transformation of rice, melon, pepper and peach.•Breeding in ornamental species.•Technology transfer to the private sector.•

1. Crop genomics Sub-programmeThe different activities of the Genomics Sub programme are listed below. There are three main genomic program-mes in three major crops: Prunus, strawberry and melon. Additional activities in this subprogramme are a breeding project in Pelargonium and two Research Units with priva-te companies.

1.1 Prunus Genomics

1.2 Strawberry Genomics

1.3 Melon Genomics

1.4 Pelargonium Breeding

2. Plant in Vitro CultureIRTA’s Plant in Vitro Culture laboratory has focused on the applications of plant tissue culture to facilitate or comple-ment plant breeding. Plant in vitro culture offers several techniques that complement traditional plant breeding methods. Micropropagation provides rapid multiplica-tion of newly selected individuals, or facilitates the pro-pagation of recalcitrant species. Other techniques, such as in vitro embryo rescue, facilitate the recombination of genotypes which might be limited by incompatibility, or the recovery of plants from crosses with developmental restrictions. Conventional breeding procedures emplo-ying the production of hybrids can be hastened by the in vitro generation of homozygous doubled haploid lines, via androgenesis, gynogenesis, or in situ induced par-thenogenesis. Contrasting, the generation of tetraploids enables the production of plants with desirable charac-ters, such us morphology changes, sterility, and seedless fruits. Undoubtedly, the application of molecular biology, genetic engineering, and genetically modified organisms (GMO), has a profound impact on plant breeding. Howe-ver, their application on some crops depends on the abili-ty to regenerate whole plants from the genetically trans-formed cells or tissues. The techniques of plant in vitro

14

3. O

ur d

epa

rtm

ents

culture continue to play an important role to facilitate their application.

2.1 MicropropagationContact person: Ramon Dolcet-Sanjuan

2.2 Embryo rescueContact person: Elisabet Claveria

2.3 Generation of Doubled Haploid Lines and PoliploidsContact person: Ramon Dolcet-Sanjuan

2.4 Genetic TransformationContact person: Victoria Marfa

2.5 Coexistence and Genetic FlowContact person: Joaquima Messeguer

Animal Genetics DepartmentThe Animal Genetics Department in CRAG (UAB) performs research activities in animal genomics and in quantitative and population genetics of domestic animals. Scientists of the Department are experienced researchers in molecular and quantitative genetics, QTL detection and expression

studies in cattle, pigs and small ruminants. The group is an officially recognized quality research group (Generalitat de Catalunya, GRC 2009SGR-100) since 1989.

The main research activities of the Animal Genetics De-partment are:

QTL characterization and gene discovery of characters •of economical interest in domestic animals.Structural and functional genomics of porcine and ru-•minant species.Use of molecular markers and implementation of Ge-•nomic Selection in domestic animals.Host-pathogen interaction in the resistance/suscepti-•bility to infectious diseases in farm animals.Genetic conservation of endangered local breeds of •domestic animals.Development of statistical and computational tools in •animal genomics.Study of the effects of domestication and artificial se-•lection in livestock species.Technology transfer to the private sector.•

1. Farm Animal GenomicsThe activities of the group have a strong commitment towards the development of new tools for high throughput genomics in domestic animals, among them, the applica-tion of genotyping to gene identification of economical value traits in farm animals particularly in pigs.

1.1. Genomics of the Host-Pathogen interactions in pigs. Armand Sánchez bonastre

15

3. O

ur d

epa

rtm

ents

1.2. Study of the Resistance/Susceptibility to infectious diseases. Olga Francino Martí Laura Altet Sanahuges 1.3. QTL characterization and gene discovery of meat quality traits in pigs. Josep Maria Folch Albareda 1.4. Gene discovery and functional genomics of fat composition and fatty acid metabolism in domestic animals. Marcel Amills Eras

1.5. Conservation Genetics of local breeds. Jordi Jordana Vidal

2. Statistical and Computational tools applied to Animal Breeding and Quantitative GeneticsMost of the traits that are of socio economic importance in domestic animals are complex, and genes involved in the-se traits difficult to characterize because their effects are usually small and confounded. The main area of research of the group is to develop statistical and computational tools that help us to identify these genes. The group is also concerned with studying how man has shaped the pattern of genetic variation in livestock species, mainly in the pig, through domestication and artificial selection.

2.1. Development od statistical and computational tools in animal genomics. Miguel Pérez-Enciso

2.2. Study of the effects of domestication and artificial selection in livestock species. Sebastián Ramos-Onsins

Core FacilitiesCore Microscopy Facility•Detection of Genetically Modified Organisms •Genomic Service•Greenhouses and Plant growth facilities Service (GPS) •IRTAGEN •Platform for protemic studies•Second generation sequencing •Sequencing Service•

16

3. O

ur d

epa

rtm

ents

4. Scientific Activity

17

4. S

cien

tific

Act

ivity

Research projects

Nr. Amount

Founded by national R+D programmes 50 2.819.766,00 €

Founded by the European Union 8 440.657,65 €

Founded by other international research funds 4 184.134,40 €

TOTAL 62 3.444.558,00 €

5%

85%

13%

Scientific output

77 SCI/SSCI papers

0 Non-SCI/SSCI papers

4 Artículos técnicos

5 Books

5 Doctoral theses

18

3. O

ur d

epa

rtm

ents

5. Human Resources

19

5. H

uma

n Res

ourc

es

People working at CRAG

CSIC IRTA UAB CRAG OTROS

Scientist 26 14 13 29 11

PhD Students 10 4 8 10 52

R+D Suport 11 12 3 25 0

Administration 1 1 0 7 1

TOTAL 48 31 24 71 64

27%

13%

20%

30%

10%

20

3. O

ur d

epa

rtm

ents

6. Financial Resources

21

6. F

ina

ncia

l Res

ourc

es

Budget distribution 2008

Budget by funder

From DIUE 969.000 €

Competitive Calls for research projects 3.444.558 €

Contracts + Services 477.240 €

TOTAL BUDGET 4.890.798 €

Expenses by kind

Staff 377.289,09 €

Operating expenses 4.362.536,96 €

Investments 2.518.941,27 €

TOTAL 7.258.767,00 €

5%

60%

35%

Human resources and infrastructure contribution

Scientific Staff Support Staff Research Training Exploitation Investments

CSIC 1.471.892 € 309.214 € 37.307,00 € 470.388,14 € 250.000 €

IRTA 840.159 € 248.199 € 55.805,00 € 114.871,27 € 1.055.175 €

UAB 333.457 € 35.474 € 12.267,00 € 136.315,11 € -

GENERALITAT - - - 1.474.844,62 € -

OTROS 292.167 € - - - -

TOTAL 2.937.675 € 592.887 € 105.379 € 2.196.419,14 € 1.305.175 €

22

3. O

ur d

epa

rtm

ents

7. Appendix I Projects & Contracts

23

7. A

pp

end

ix I

A. Caño Delgado (16211)

J. Martínez García (16222)

P. Suárez López (16223)


P. Puigdomènech Rosell (16227)

M. Pagès Torrent (16228)

D. Ludevid Mugica

E. Monte Collado (16237)

J. M. Torné Cubiró (16238)

J. M. Casacuberta Suñer (16239)

S. Pelaz Herrero (16240)

M. Pagès Torrent (16241)

B. Sansegundo De Los Mozos (16242)

J. Martínez Garcia (16247)

P. Mas Martínez (16248)

B. Sansegundo (16250)

D. Ludevid Mugica (16252)

CDA 007 / 2004-C

BIO2005-00154

BIO2005-00717

BIO2005-01447

SGR 05/182

SGR 05/276

Contrato empresa

BIO2006-09254

BFU2006-15115-C02-01

BFU2006-04005

BFU2000-00771

BIO2006-04101

BIO2006-05583

BIO2006-26104-E

EUROHORCS (EURYI AWARD)

GEN2006-27794-C4-1-E/VEG

GEN2006-27793-C2-2-E/VEG

International Human Frontier Science Program Organization

MICINN - Ministerio de Ciencia e Innovación



AGAUR - Agencia de Gestión de Ayudas Uni-versitarias - Generalitat

AGAUR - Agencia de Gestión de Ayudas Uni-versitarias - Generalitat

ERA PLANTECH, S.L.MICINN - Ministerio de Ciencia e Innovación








EUROHORCS (a través de CSIC)

MICINN - Ministerio de Ciencia e Innovación (PLANT-KBBE)

MICINN - Ministerio de Ciencia e Innovación (PLANT-KBBE)

01/04/2005

31/12/2005

31/12/2005

31/12/2005

18/10/2005

18/10/2005

01/03/2006

01/10/2006

01/01/2007

01/10/2006

01/10/2006

01/10/2006

01/10/2006

01/01/2007

01/04/2007

01/04/2007

18/10/2005

31/03/2008

31/12/2008

31/12/2008

15/10/2008

31/12/2008

31/12/2008

28/02/2008

30/09/2009

30/09/2009

30/09/2009

30/09/2009

30/09/2009

30/09/2009

31/12/2008

31/03/2012

31/03/2010

31/03/2010

80.601,68 €

154.700,00 €

107.100,00

95.200,00

49.600 €

36.600 €

186.000 €

174.240 €

157.300 €

121.000 €

168.069 €

384.780 €

317.746 €

25.000 €

1.250.000 €

300.000 €

122.000 €

Human Frontiers Scientific Program Career Development Award.

Control genético y espacial del síndrome de huidade la sombra en Arabidopsis Thaliana.

Señalización a distancia en desarrollo vegetal: Formación de tuberculos y floración.

Análisis genético de la ontogenia vascular del floema en Arabidopsis Thaliana.

Grupo de Investigación consolidado en genética molecular vegetal.

Grupo de Investigación consolidado en estrés abiótico de plantas.

ERA PLANT-Proteínas eucariotas.

Análisis genético y establecimiento proteómico de la plántula en la transición de oscuridad a luz en Arabidopsis Thaliana.

Caracterización de las transglutaminasas cloroplásticas de maíz TGZ, interacción con otras proteínas plastidiales y mejora de su expresión en organismos unicelulares.

Control de la transposición e impacto de los elementos transponibles en la regulación génica.

Control genético de la inducción floral y del desarrollo de la flor en Arabidopsis.

Genes regulados por ABA y estrés osmótico en plantas.

Mecanismos reguladores de respuesta de defensa de las plantas mediados per proteínas quinasa dependientes de calcio y micrornas. Estudio comparativo entre Arabidopsis Thaliana y arroz.

Red de desarrollo y diferenciación vegetal (acción complementaria).

EURYI Understanding the biological clock in Arabidopsis Thaliana: Global approaches to study mechanisms of clock function.

TRIESTER:Trilateral initiative for enhancing salt tolerance in rice.

PROTEIN STORAGE: An integrated genomic and proteomic characterization of artificial seed storage organelles for the optimal production ofbiopharmaceuticals in plants and plant cells.

Project Leader Titlle Reference Financial Institution Start End Funding

24

7. A

pp

end

ix I

E. Monte Collado (16253)


C. Vicient Sanchez (16257)


J. J. López Moya (16259)

B. Sansegundo De Los Mozos (16260)

J. Rigau Lloveras (16261)

J. M. Casacuberta Suñer (16262)

T. Esteve Nuez.; J. Messeguer Peypoch (16264)


T. Esteve Nuez (16267)

D. Ludevid Mugica


J.L. Riechmann Fernández (16271)

L. M. Lois Rojas (16272)

B. Sansegundo De Los Mozos (16274).

Dark signalling mechanisms involved in the regulation of the developmental switch from dark to light growth in Arabidopsis seedlings.

Ampliación del mapa físico y aplicación al análisis de los carácteres de forma del fruto del melón (Cucumis melo).

Identificación y caracterización de familias génicas implicadas en el desarrollo embrionario en plantas.

Caracterización molecular e implicaciones funcionales de Sant-1 en el sistema circadiano de arabidopsis.

Análisis derivados de virus de la familia Potyviridae funcionales en transmisión por insectos y en supresión de defensas en plantas.

Cell-specific profilling of gene expression in arbuscular mycorrhizal roots (acción integrada).

Decreasing ligning content maize and sugarcane to improve bioethanol production from agricultural waste (acción integrada).

Análisis de la transposición de los elementos Miter Physcomitrella Patens (acción integrada).

Variabilidad asociada a la inserción y expresión de transgenes en plantas.

Consolider: Centro de Genómica básica y de orientación agroalimentaria.

Cuantificación del contenido en OGMs y micotoxinas en parcelas comerciales de maíz: predicción y técnicas de muestreo.

ERA BIOTECH-Proteínas Eucariotas 2006-2008

EMBO Young Investigators Award 2007: Circadian Rhythm in Arabidopsis.

GEANARAFDEV: Genomic Analyses of Arabidopsis Flower Development: sORFs, miRNAs, and transcription factor-coding genes.

SUMO: Study of the role of the protein posttranslational modification by SUMO (Small Ubiquitin-like MOdifier) in abscisic acid signaling and stress responses in plants.

Red de referencia de I+D+I en Biotecnología.

MIRG-CT-2007-046568

BIO2007-61789

BIO2007-64791

BIO2007-66068

AGL2007-60229

HI2007-0258

HS2007-0021

HF2007-0116

PIA 12007-4 UdG

CSD2007-00036

RTA2007-00006-00-00 (IRTA)

Contrato empresa

BIO2008-04491-E

PIRG-GA-2007-224864

ERC-GA-2007-StG-205927

Convenio

01/06/2007

01/10/2007

01/12/2007

01/10/2007

01/10/2007

01/01/2008

01/01/2008

01/01/2008

28/01/2008

01/10/2007

04/09/2007

01/03/2008

01/01/2008

01/04/2008

01/07/2008

01/01/2008

Comisión Europea - Marie Curie GrantMICINN - Minis-terio de Ciencia e Innovación

MICINN - Minis-terio de Ciencia e Innovación






UNIVERSITAT DE GIRONA (MICINN)


IRTA - INSTITUT DE RECERCA I TECNO-LOGIA AGROALI-MENTARIA (INIA)

ERA BIOTECH, S.A.

EMBO European Molecular Biology Organization

Comisión Europea - Marie Curie Grant

Comisión Europea - IDEAS Starting Grant

Departamento de Innovación, Univer-sidades y Empresa - GENERALITAT

Comisión Europea - Marie Curie GrantEC

31/05/2009

04/10/2010

30/11/2008

04/10/2010

04/10/2010

31/12/2009

31/12/2009

31/12/2009

04/10/2010

29/11/2012

03/09/2010

28/02/2009

31/12/2010

31/03/2012

30/06/2013

31/12/2009

80.000 €

245.630 €

36.300 €

143.990 €

157.000 €

11.490 €

11.490 €

11.490 €

96.500 €

3.500.000 €

20.000 €

104.000 €

65.000 €

100.000 €

945.628 €

76.957,12 €

Project Leader Titlle Reference Fin. Institution Start End Funding

25

7. A

pp

end

ix I


Armand Sánchez

Marcel Amills

Marcel Amills

Marcel Amills

Luis Silió López (Coordinador), A. Sánchez (UAB)

José María Folch Albareda

Armand Sánchez

Miguel Pérez-Enciso

Jordi Jordana

A. Sánchez

A. Sánchez

L. Altet

O. Francino

O. Francino

A. Sánchez

A. Sánchez

BRAVISSIMO: BRAssinosteroid Venture Increasing StudentS’ International MObility.

Unravelling the molecular basis of common complex human disorders using the dog as a model system (LUPA)

Caracterización genética de las razas caprinas Blanca de Rasquera, Ibicenca, Azpi Gorri,Ajuí y Tinerfeña del Sur y análisis comparativo con otras poblaciones caprinas.

Mapeo e identificación de genes implicados en el metabolismo lipídico en porcino, la calidad de la carne y la calidad del jamón curado.

Cartografiado e identificación de genes implicados en el metabolismo lipídico en porcino. Expresión genómica de QTL y genes candidatos para calidad de carne en diversas líneas de porcino.

Estudio genético del tamaño de camada y sus componentes tasa de ovulación y superviviencia prenatal.

Análisis genómico mediante microarrays de la arquitectura genética de fenotipos complejos en porcino.

La huella de la domesticación y la selección sobre genes candidatos del metabolismo adiposo y del comportamiento en porcino: Estudio poblacional.

Análisis genético del contenido y composición de la grasa de la leche de cabra.

DNA based selection to develop pork concepts for meat and carcass quality.

Identificació genètica i traçabilitat en porcí selecte.

Establecimiento de un programa de control para la toma de decisiones para la liberación de ejemplares de tortuga mora al medio natural en la región de Murcia.

Detección del origen específico (porcino) y detección de contaminación (bovino, ovino, caprino) sobre muestras de materia prima y procesada de origen animal.

Detección del origen específico (porcino) y detección de contaminación (bovino, ovino, caprino) sobre muestras de materia prima y procesada de origen animal.

Identificación individual por microsatélites en muestras fecales congeladas o desecadas de lobo.

Identificación individual por microsatélites en pelos o muestras fecales congeladas o desecadas de oso pardo.

PITN-GA-2008-215118

HEALTH-2007-2.1.1-7

RZ2007-00005-C02-01

AGL2007-66707-C02-02

PRP2007-01

CPE03-010-03

AGL2005-07624-C03-02

GEN2003-20658-C05

AGL2007-65563-C02-01/GAN

AGL2007-66161-C02-02

01/09/2008

2008

2007

2007

2007

2005

2005

2004

2007

2007

2004

2005

2005

2005

2005

2006

INIA

CICYT

UAB

Acción estratégica del CPE03-010-03.

CICYT

MCYT -Proyectos integrados de investi-gación de Genómica y Proteómica

MICINN

MICINN

Eurhibrid España

IRTA

Hospital Clínico Veterinario

Universidad de Murcia

PROBISA S.A

BIOIBÉRICA S.A.

Forestal Catalana/Departament de Medi Natural. Generalitat de Catalunya

Forestal Catalana/Dept. de Medi Natural. Gene-ralitat de Catalunya

Departamento de Medio Ambiente. Junta de Castilla León.

31/08/2012

2011

2009

2009

2008

2008

2008

2008

2010

2010

2008

2008

2008

2008

2008

2008

231.271 €

150.000 €

45.600 €

85.000 €

6.000 €

205.892 €

49.980 €

156.000 €

157.300 €

113.740 €

182.000 €

69.411 €

22.897 €

179.055 €

433.608 €

43.735 €

11.200 €

Project Leader Titlle Reference Financial Institution Start End Funding

26

7. A

pp

end

ix I

A. Sánchez

P. Cabot Roig

R. Dolcet Sanjuan

J. Bonany

L. Asin Jones

R. Dolcet Sanjuan

J. Messeguer Peypoch

J. Messeguer Peypoch

M. Monfort Vives

R. Dolcet Sanjuan

J. Bonany

X. Aranda Frattarola

Identificación individual por microsatélites en muestras fecales congeladas o desecadas de lobo.

Prospecció, recol·lecció i conservació de germoplasma, selecció, estudis de propagació i cultiu ecològic de poblacions silvestres d’espècies de plantes aromàtiques i medicinals de la flora espanyola.

Millora genètica de porta-empelts de perer.

Programa de millora genètica de fruita dolça en col·laboració amb el sector català.

Millora genètica i selecció de nous portaempelts de perer enanitzants i resistents a la clorosi fèrrica.

Desenvolupament d’una tècnica per a la producció de línies pures de tomàquet (Lycopersicon esculentum Mill.) mitjançant l’obtenció de línies dihaploids (LDHs) per androgènesi, ginogènesi o partenogènesi.

Aportació d’un model per a una aproximació multidisciplinària per gestionar la coexistència de les afiliacions OGM i no OGM en el blat de moro.

Quantificació del contingut en OGMs i micotoxines en parcel·les comercials de blat de moro: predicció i tècniques de mostreig.

Ús dels marcadors moleculars per a la construcció d’una col·lecció de línies quasi isogèniques en maduixa diploide (Fragaria vesca) i la comparació dels genomes de Fragaria i Prunus.

Desenvolupament protocol adreçat la producció de línies pures de tomàquet (Lycopersicum esculentum Mill.)mitjançant la generació androgènica de línies doble haploides (LDHs).

Fomentar el consum de fruita mitjançant un enfocament transdisciplinar orientat a la consecució d’una producció d’alta qualitat a partir de mètodes segurs, sostenibles i respectuosos amb el medi ambient.

Valorització no alimentària de productes agrícoles

11152Aromàtiques i Medicinals

12087 Porta-empelts perer

12156 Millora 3P

12263 Perer resistent clorosi fèrric

16075 Línies pures tomàquet

16080 Coexistència OGM i no OGM blat

16082 OGMs i micotoxines

16083 Marcadors maduixa diploide

16086 Línies pures de tomàquet

91140 ISAFRUIT

91153 AGRIVAL

2008

28/11/2005

01/01/1999

01/04/2002

28/11/2005

23/05/2005

01/01/2007

04/09/2007

04/09/2007

07/08/2008

01/01/2006

01/01/2007

I.N.I.A.

DIUE ; GENE-RALITAT DE CATALUNYA ; NOCLIENT

CLIENTS VARIS ; DAR ; FRUIT FUTUR A.I.E. ; GENERALITAT DE CATALUNYA ; NOCLIENT

I.N.I.A.

I.N.I.A.

I.N.R.A.

I.N.I.A.

I.N.I.A.

I.N.I.A.

CLIENTS VARIS ;

IRTA ; UE

IRTA ; UE

2009

31/12/2009

31/12/2008

31/12/2050

28/07/2009

22/05/2008

31/12/2009

03/09/2010

03/09/2010

06/08/2011

30/09/2010

30/06/2008

18.000 €

1.770,39 €

0 €

7.938,45 €

6.027,12 €

20.178,42 €

12.107,41 €

23.191,80 €

38.504,20 €

0 €

18.358,31 €

48.090,41 €

Project Leader Titlle Reference Fin. Institution Start End Funding

27

7. A

pp

end

ix I

28

3. O

ur d

epa

rtm

ents

8. Appendix II Papers

29

8. A

pp

end

ix II

Molecular Genetic Departament

Campo, S., Manrique, S., García-Martínez, J., San Segundo, B. (2008) Production of cecropin A in trawnsgenic rice plants has an impact on host gene expresión. Plant Biotechnology J. 6, 585-608.

Quilis, J., Peñas, G., Messeguer, J., Brugidou, C., San Segundo, B. (2008) Arabidopsis AtNPR1 inversely modulates defense responses against fungal, bacterial or viral pathogens while conferring hyper-sensitivity to abiotic stresses in transgenic rice. Molecular Plant-Mi-crobe Interaction. 21, 1215-1231.

Ramallo, E., Kalendar, R., Schulman, A., Martínez-Izquierdo, J.A.(2008) Reme1, a Copia retrotransposon in melon, is transcriptionally induced by UV light. Plant Mol. Biol. 66: 137-150. Jump, A. S., Peñuelas, J., Rico. L., Ramallo, E., Estiarte, M., Martínez-Izquierdo, J. A., Lloret, (2008) F. Simulated climate change provokes rapid genetic change in the Mediterranean shrub Fumana thymifolia. Global Change Biol. 14: 637-643.

Rodríguez-Villalón, A., Pérez-Gil, J., Rodríguez-Concepción, M. (2008) Carotenoid accumulation in bacteria with enhanced supply of iso-prenoid precursors by upregulation of exogenous or endogenous pa-thways. J. Biotechnol. 135: 78-84.

Flores-Pérez, U., Pérez-Gil, J., Rodríguez-Villalón, A., Gil, M.J., Vera, P., Rodríguez-Concepción, M. (2008) Contribution of hydroxymethylbu-tenyl diphosphate synthase to carotenoid biosynthesis in bacteria and plants. Biochem. Biophys. Res. Commun. 371: 510-514.

Flores-Pérez, U., Sauret-Güeto, S., Gas, E., Jarvis, P., Rodríguez-Con-cepción, M. (2008) A mutant impaired in the production of plasto-me-encoded proteins uncovers a mechanism for the homeostasis of isoprenoid biosynthetic enzymes in Arabidopsis plastids. Plant Cell 20:1303-1315.

Ahumada, I., Cairó, A., Hemmerlin, A., González, V., Pateraki, I., Bach, T.J., Rodríguez-Concepción, M., Campos, N., Boronat, A. (2008) Cha-racterization of the gene family encoding acetoacetyl-CoA thiolase in Arabidopsis. Funct. Plant Biol. 35: 1100-1111.

Phillips, M.A., León, P., Boronat, A., Rodríguez-Concepción, M. (2008) The plastidial MEP pathway: unified nomenclature and resources. Trends Plant Sci. 13: 619-623.

Castillejo, C., Pelaz, S.(2008) The balance between CONSTANS and TEMPRANILLO activities determines FT expression to trigger flowe-ring. Current Biology, 18, 1338-1343.

Tapia-López, R., García-Ponce, B., Dubrovsky, JG., Garay, A., Pérez-Ruíz, R., Sun-Hyung Kim, Acevedo, F., Pelaz, S., Alvarez-Buylla, E.R. (2008) An AGAMOUS-related MADS-box gene, XAL1 (AGL12), regulates root meristem cell proliferation and flowering transition in Arabidop-sis thaliana. Plant Physiology, 146, 1182-1192.

Leivar P*, Monte E*, Al-Sady B, Carle C, Storer A, Alonso JM, Ecker JR, Quail PH (*Equal contribution) (2008) The Arabidopsis Phytochrome-Interacting Factor PIF7, Together with PIF3 and PIF4, Regulates Res-ponses to Prolonged Red Light by Modulating phyB Levels. Plant Cell 20: 337-352. Al-Sady, B., Kikis, E.A., Monte , E.(2008) Quail PH. Mechanistic duality of transcription factor function in phytochrome signalling. PNAS 105: 2232-2237 Stratmann, T., Más, P. (2008) Chromatin, photoperiod and the Ara-bidopsis circadian clock: a question of time. SEMINARS IN CELL AND DEVELOPMENTAL BIOLOGY 19: 554–559, (COVER).

Más, P. (2008) Circadian clock function in Arabidopsis thaliana: time beyond transcription. TRENDS IN CELL BIOLOGY. 18(6):273-281.

Más, P. (2008) Chromatin remodelling and the Arabidopsis biological clock. PLANT SIGNALLING & BEHAVIOUR . 3(2):121 - 123.

Radek, K. (1)., López-García, B., (1), Hupe, M., Niesman, I., Elias, P.M., Taupenot, L., Mahata, S.K., O´Connor, D.T., Gallo, R.L.* (2008) The neuroendocrine peptide catestatin is a cutaneous antimicrobial and induced in the skin after injury. J. Invest. Dermatol. 128: 1525-1534.

30

8. A

pp

end

ix II

Marcos, J.F.*, Muñoz, A., Pérez-Payá, E., Misra, S., López-García, B. (2008) Identification and rational design of novel antimicrobial pepti-des for plant protection. Annu. Rev. Phytopathol. 46: 273-301

Genovesi, V., Fornalé, S., Fry, SC., Ruel, K., Ferrer, P., Encina, A., Sonbol, FM., Bosch, J., Puigdomènech, P., Rigau, J., Caparrós-Ruiz, D. (2008) ZmXTH1, a new xyloglucan endotransglucosylase/hydrolase in maize, affects cell wall structure and composition in Arabidopsis thaliana. Journal of Experimental Botany 59:875-89.

Voldria destacar que aquest treball s’ha fet en col·laboració, entre d’altres, del Dr. Pau Ferrer, del Departament d’Enginyeria Química, Universitat Autònoma de Barcelona, que també pertany a la Xarba.Pujals, S., Fernandez-Carneado, J., Ludevid, MD., Giralt, E. (2008) D-SAP: A new noncytotoxic and fully protease resistant cell-penetra-ting peptide.ChemMedChem 3, 296-301

Marzabal, P., Gas, E., Fontanet, P., Vicente-Carbajosa, J., Torrent, M., Ludevid, MD. (2008) The maize Dof protein PBF activates transcrip-tion of -zein.Plant Mol. Biol. 67:441-454.

Jasinski, S., Tattersall, A., Piazza, P., Hay, A., Martinez-Garcia, JF., Sch-mitz, G.(2008) Theres K, McCormick S, and Tsiantis M (2008). PROCE-RA encodes a DELLA protein that mediates control of dissected leaf form in tomato. Plant J 56, 603-612.

Bou-Torrent, J., Roig-Villanova, I., Martínez-García, JF.© (2008). Light signaling: back to space. Trends Plant Sci 13, 108-114.

Bou-Torrent, J., Roig-Villanova, I., Galstyan, A., Martínez-García, JF.© (2008). Addendum: PAR1 and PAR2 integrate shade and hormone transcriptional networks. Plant Signal Behav 3, 453-454.

Deragon, JM., Casacuberta, JM., Panaud, O.(2008) Plant transposable elements. Volff J-N (ed): Plant Genomes. Genome Dyn. Basel, Karger, vol 4, pp 69-82 .

Guermonprez, H., Loot, C., Casacuberta, JM. (2008) Different strategies to persist: the pogo-like Lemi1 transposon produces MITEs or typical defective elements in different plant genomes. Genetics180, 83-92.

Benjak, A., Fornek, A., Casacuberta, JM.(2008) Genome-wide analy-sis of the “cut-and-paste” transposons of grapevine. PLoS One 3, e3107.

SEQUENCES: Repbase Reports 8 (7), 755-778 (2008)

Coll, A., Nadal, A., Palaudelmàs, M. Messeguer, J., Melé, E., Puigdomè-nech, P., Pla, M. (2008) Lack of repeatable differential expresión pat-tems between MON810 and comparable comercial varieties of maite. Plant Mol Biol. 68(1-2):105-17. Epub 2008 Jul 6.

Puigdomènech, P. (2008) Spain: leading role of scientists is hearte-ning. Nature 453(7191):27

Fulgenzi, FR., Peralta, ML-. Mangano, S., Danna, CH, Vallejo, AJ., Puigdomènech, P., Santa-María, GE. (2008) The ionic environment controls the contributiion of the barley HvHAK1 transporter to potas-sium acquisition. Plant Physiol. 147(1):252-62.

Reyes-Irisarri, E., Pérez-Torres, S., Miró, X., Martínez, E. Puigdomè-nech, P., Palacios, JM, Mengod, G. (2008) Differential distribution of PDE4B sílice variant mRNAs in rat brain and the effects of systemic administration of LPS IN THEIR EXPRESSION. SYNAPSE 62(1):74-9.

Plant Genetics Departament

Al-Faifi, S.; Meyer, J.D.F; Garcia-Mas, J.; Monforte, A.J.; Havey, M.J. (2008). Exploiting synteny in Cucumis for mapping of Psm: a unique locus controlling paternal mitochondrial sorting. Theoretical and Applied Genetics 117 :523-529

Asín, L.; Dolcet-Sanjuan, R.; Claveria, E.; Vilardell, P.; Bonany, J.; Iglesias, I.; Simard, M.H. (2008). INRA-IRTA Pear rootstock breeding program: Ai-ming for tolerance to iron chlorosis . Acta Horticulturae (en premsa).

Cabot, P. (2008). El ahorro de agua en jardinería. Actas de Horticultura 52 :48-49.

31

8. A

pp

end

ix II

Cabot, P.; Fanlo, M. (2008). Estudio del enraizamiento de estaquillas de Lavandula latifolia Medic. y Salvia lavandulifolia Vahl en diferen-tes concentraciones hormonales. Actas de Horticultura (cd-rom) 52 :355-359.

Chen, L.; Zhang, S.M.; Illa, E.; Song, L.J.; Wu, S.D.; Howad, W.; Arús, P.; Van de Weg, E.; Chen, K.S.; Gao, Z.S. (2008). Genomic characte-rization of putative allergen genes in peach/almond and their syn-teny with apple [en línia]. BMC Genomics. 9 : 543 [Consulta: 16 febrer 2009] <http://www.biomedcentral.com/1471-2164/9/543>.

Coll, A.; Nadal, A.; Palaudelmàs, M.; Messeguer, J.; Melé, E.; Puig-domènech, P.; Pla, M. (2008). Lack of repeatable differential expres-sion patterns between MON810 and comparable commercial varieties of maize. Plant Molecular Biology 68 :105-117

Dolcet-Sanjuan, R.; Claveria, E.; Asín, L.; Vilardell, P.; Bonany, J.; Si-mard, M.H. (2008). Towards the selection of a new pear rootstock: in vitro and field evaluation for tolerance to iron chlorosis, low vigor and micropropagation of selected clones. Acta Horticulturae 800 (2 ):683-690

Fernandez-Silva, I.; Eduardo, I.; Blanca, J.; Esteras, C.; Picó, B.; Nuez, F.; Arús, P.; Garcia-Mas, J.; Monforte, A.J. (2008). Bin mapping of ge-nomic and EST-derived SSRs in melon (Cucumis melo L.). Theoretical and Applied Genetics 118 :139-150

Martin-Hernandez, A.M.; Baulcombe, D. (2008). Tobacco Rattle virus 16K encodes a suppressor of RNA silencing that allows transient viral entry in meristems. Journal of Virology 82 :4064-4071

Meyer, J.D.F; Deleu, W.; Garcia-Mas, J.; Havey, M.J. (2008). Construc-tion of a fosmid library of cucumber (Cucumis sativus) and compa-rative analyses of the eIF4E and eIF(iso)4E regions from cucumber and melon (Cucumis melo). Molecular Genetics and Genomics 279 :473-480

Moreno, E.; Obando, J.M.; Dos-Santos, N.; Fernández-Trujillo, J.P.; Monforte, A.J.; Garcia-Mas, J. (2008). Candidate genes and QTLs for

fruit ripening and softening in melon. Theoretical and Applied Gene-tics 116 :589-602

Obando, J.; Fernández-Trujillo, J.P.; Martínez, J. A.; Alarcón, A.L.; Eduardo, I.; Arús, P.; Monforte, A.J. (2008). Identification of Melon Fruit Quality Quantitative Trait Loci Using Near-isogenic Lines . Journal of the American Society for Horticultural Science 133 :139-151

Obando, J.; Moreno, E.; Garcia-Mas, J.; Nicolai, B.; Lammertync, J.; Monforte, A.J.; Fernández-Trujillo, J.P. (2008). Climacteric or non-climacteric behavior in melon fruit 1.Linking climacteric pattern and main postharvest disorders and decay in a set of near-isogenic lines. Postharvest Biology and Technology 49 :27-37

Palaudelmàs, M.; Melé, E.; Peñas, G.; Pla, M.; Nadal, A.; Serra, J.; Salvià, J.; Messeguer, J. (2008). Sowing and flowering delays can be an efficient strategy to improve coexistence of GM and conventional maize. Crop Science 48 :2404-2413

Rousseau-Gueutin, M.; Lerceteau-Köhler, E.; Barrot, D.; Sargent, D.J.; Monfort, A.; Simpson, D.W.; Arús, P.; Guérin, G.; Denoyes-Rothan, B. (2008). Comparative genetic mapping between octoploid and diploid Fragaria species reveals a high level of colinearity between their ge-nomes and the essentially disomic behavior of the cultivated octo-ploid strawberry. Genetics 179 :2045-2060.

Sargent, D.J.; Cipriani, G.; Vilanova, S.; Gil-Ariza, D; Arús, P.; Simp-son, D.W.; Tobutt, K.R.; Monfort, A. (2008). The development of a bin mapping population and the selective mapping of 103 markers in the diploid Fragaria reference map. Genome 51 :120-127

Shulaev, V.; Korban, S.S.; Sosinski, B.; Abbot, A.G.; Aldwinckle, H.S.; Folta, K.M.; Lezzoni, A.; Main, D.; Arús, P.; Dandekar, A.M.; Lewers, K.; Brown, S.K.; Davis, T.M.; Gardiner, S.E.; Potter, D.; Veilleux, R.E. (2008). Multiple models for Rosaceae genomics. Plant Physiology 147 :985-1003

Vilanova, S.; Sargent, D.; Arús, P.; Monfort, A. (2008). Synteny conser-vation between two distantly-related rosaceae genomes: Prunus (the stone fruits) and Fragaria (the strawberry) [en línia]. BMC Plant Biolo-gy. 8 ( ): 67 [Consulta: 16 febrer 2009] <http://www.biomedcentral.com/1471-2229/8/67>

32

8. A

pp

end

ix II

Zhebentyayeva, T.; Swire-Clark, G.; Georgi, L.L.; Garay, L.; Jung, S.; Fo-rrest, S.; Blenda, A.V.; Blackmon, B.; Mook, J.; Horn, R.; Howad, W.; Arús, P.; Main, D.; Tomkins, J.P.; Sosinski, B.; Baird, W.V.; Reighard, G.L.; Abbott, A.G. (2008). A framework physical map for peach, a mo-del Rosaceae species. Tree Genetics& Genomes 4 (4 ):745-756

Departamento de Genética Animal

Amills M, O. Ramírez, A. Tomàs, G. Obexer-Ruff and O. Vidal. 2008. Positive selection on mammalian MHC-DQ genes revisited from a multispecies perspective. Genes and Immunity 9(8):651-658.

Amills M., Villalba D., Tor M., Mercader A., Gallardo D., Cabrera B., Jiménez N., Noguera JL., Sánchez A. y J. Estany. 2008. Plasma leptin levels in pigs with different leptin and leptin receptor genotypes: Jo-urnal of Animal Breeding and Genetics 125: 228-233.

Casellas J., Varona L., Muñoz G., Ramirez O., Barragan C., Tomás A., Martinez M., Ovilo C., Sánchez A., Noguera J.L. y M.C. Rodriguez. 2008. Bayes factor analyses of quantitative trait loci for gestation length in Meishan × Iberian F2 sows. Animal: An International Journal of Animal Bioscience 2(2):177-183.

Casellas J., Tomás A., Sánchez A., Alves E., Noguera J.L. y J. Piedrafita. 2008. Using haplotype probabilities in categorical 1 survival analysis: A case study with three candidate genes in an Iberian × Meishan F2 population of newborn piglets. Journal of Animal Breeding and Gene-tics125: 5-12.

Caravaca F., Amills M., Jordana J., Angiolillo A., Agüera P., Aranda C., Menéndez-Buxadera A., Sánchez A., Carrizosa J., Urrutia B., Sànchez A. y J.M. Serradilla. 2008. Effect of αs1-casein (CSN1S1) genotype on milk CSN1S1 content in Malagueña and Murciano-Granadina goats. Journal of Dairy Research 75:481-484.

Estellé J, Gil F, Vázquez JM, Latorre R, Ramírez G, Barragán MC, Folch JM, Noguera JL, Toro MA, Pérez-Enciso M. 2008 A QTL genome scan for porcine muscle fiber traits reveals overdominance and epistasis. Journal of Animal Science 86: 3290-3299.

Ferrando A., Lecis R., Domingo-Roura X. and Ponsà M. 2008. Genetic diversity and individual identification of reintroduced otters (Lutra lu-tra) in north-eastern Spain by DNA genotyping of spraints. Conserva-tion Genetics, 9: 129-139.

Ferraz ALJ Ana Ojeda, Manel López-Béjar, Lana T. Fernandes, Anna Castelló, Josep M. Folch, Miguel Pérez-Enciso. 2008. Transcriptome architecture across tissues in the pig. BMC Genomics 9:173.

Gallardo D*, R.N. Pena*, M. Amills, L. Varona, O. Ramírez, J. Reixach, I. Díaz, J. Tibau, J. Soler, J.M. Prat-Cuffi, J.L. Noguera, R. Quintanilla. 2008. Mapping of quantitative trait loci for cholesterol, LDL, HDL and tryglyceride serum concentrations in pigs. Physiological Genomics 35: 199-209. *Primera autoría compartida

Gallardo D, Cánovas E, López-Béjar M, Ramírez O, Pena R, Quintanilla R, Amills M. 2008. Alternative splicing at exon 28 of the acetyl-coen-zyme A carboxylase alpha gene in adult pigs and embryos. Animal Genetics. 39: 205-206.

Lecis R., Ferrando A., Ruiz-Olmo J., Mañas S. and Domingo-Roura X. 2008. Population genetics structure and distribution of introduced American mink (Mustela vison) in Spain based on microsatellite varia-tion. Conservation Genetics, 9: 1149-1161.

Ojeda A, Huang LS, Ren J, Angiolillo A, I.-C.Cho, Soto H, Lemús-Flores C, Makuza SM, Folch JM, Pérez-Enciso M. 2008. Selection in the ma-king: A worldwide survey of haplotypic diversity around a causative mutation in porcine IGF2. Genetics. 178:1639-1652.

Ojeda A, Estellé J, Folch JM, Pérez-Enciso M. 2008. Nucleotide va-riability and linkage disequilibrium pattern at porcine FABP5 gene. Animal Genetics 39:468-473.

Peiró R, Merchan M, Santacreu MA, Argente MJ, García ML, Folch JM, Blasco A. 2008. Identification of Single Nucleotide Polymorphism in the Progesterone Receptor Gene and its association with reproductive traits in Rabbits. Genetics 180(3):1699-705.

33

8. A

pp

end

ix II

Pérez-Enciso M. 2008. Population and quantitative genetics for a cause. Journal of Animal Breeding and Genetics 125:217-218. (In-vited editorial)

Pérez-Enciso, M. 2008. Emerging tools for quantitative trait loci de-tection. Acta Agric Scand Section A 57:202-207 (invited review)

Ramírez O, Tomàs A, Barragan C, Noguera JL, Amills M, Varona L. 2008. Pig melatonin receptor 1a (MTNR1A) genotype is associated with seasonal variation of sow litter size. Anim Reprod Sci. [Epub ahead of print].

Ramirez O, A. Tomàs, J. Casellas, M. Blanch, J. L. Noguera and M. Amills. 2008. An association analysis between a silent C558T po-lymorphism at the pig vascular-cell adhesion molecule 1 (VCAM1) lo-cus and sow reproduction and piglet survivability traits. Reproduction in Domestic Animals 5:542-546

Ramirez-Soriano, A., Ramos-Onsins, S E.., Rozas, J., Calafell, F,. And Navarro, A. 2008. Power analysis of neutrality tests under demogra-phic expansions, bottlenecks or contractions with recombination Ge-netics 179: 555-567.

Ramos-Onsins, S. E., E. Puerma, D. Balañá-Alcaide, D. Salguero and M. Aguadé 2008. Multilocus analysis of variation using a Large Em-pirical Dataset (LED): phenylpropanoid pathway genes in Arabidopsis thaliana Molecular Ecology 17(5):1211-23.

Sastre N; O Francino; O Ramírez; C Enseñat; A Sánchez; L Altet. 2008. Detection of Leishmania infantum in captive wolves from Southwes-tern Europe. Veterinary Parasitology 158: 117-120.

Sanchez-Robert E, L. Altet, M Utzet-Sadurni, U. Giger, A. Sanchez and O. Francino. 2008. Slc11a1 (formerly Nramp1) and susceptibility to canine visceral leishmaniasis. Veterinary Research 39: 36-42.

Sanchez-Robert E, L. Altet, J. Alberola, A. Rodriguez-Cortés, A. Ojeda, L. López-Fuertes, M. Timon, A. Sanchez, O. Francino. 2008. Longitu-dinal analysis of cytokine gene expression and parasite load in PMBC in Leishmania infantum experimentally infected dogs. Veterinary im-munology and Immunopathology 125: 168-175

Tabar; MD., Laura Altet; Olga Francino; Armand Sánchez; Lluís Ferrer; Xavier Roura 2008. Vector-borne infections in cats: molecular study in Barcelona area (Spain). Veterinary Parasitology 151: 332-6.

Tabar; MD., X Roura; O Francino; L Altet; R Ruiz de Gopegui. 2008. Detection of Leishmania infantum by real-time PCR in a canine blood bank. Journal of Small Animal Practice 49: 325-328

Vidal E, Tortosa R, Costa C, Benavides J, Francino O, Sánchez-Robert E, Pérez V, Pumarola M. 2008. Lack of PrP(sc) immunostaining in intracranial ectopic lymphoid follicles in a sheep with concomitant non-suppurative encephalitis and Nor98-like atypical scrapie: a case report. Veterinary Journal 177(2):283-288.

Zidi, A., A. Sànchez, G. Obexer-Ruff and M. Amills. 2008. Sequence analysis of goat major histocompatibility complex class I genes. Jour-nal of Dary Science 91:814-817.

BOOKS

MOLECULAR GENETICS DEPARTMENT

López-Moya, JJ., García, JA. (2008) Potyviruses. In: Encyclopedia of Virology. Third Edition (B. Mahy & M. Van Regenmortel, editors). Else-vier, Oxford, UK. Vol. 4, 313-322

Fontanet, P., Vicient, CM. (2008) Maize Embryogenesis. Methods in Molecular Biology, 427: 17-30.

Almeida, A.M., Santos, D., Fevereiro P., Santos, M. and Torné, J.M. Plant genetic engineering and osmoprotectans. Research Signpost, 217-235.

Saleh, A., Lumbreras, V., Pages, M. Regulation of gene expression by ABA.

Lumbreras, V., Lopez, C., Vilela, B., Moreno, A. and Pages, M. Res-puesta de adaptación al estrés osmótico en plantas: Función de las proteínas quinasas. SnRK1/2.

34

8. A

pp

end

ix II

SCIENTIFIC ARTICLES

PLANT GENETICS DEPARTAMENT

Cabot, P. (2008). Por un uso sostenible del agua. Jardinería Profesio-nal 7 : 6-7.

Cabot, P. (2008). Utilización no alimentaria de producciones vegeta-les. Plantflor 129 :124-126.

Monfort, A.; Arús, P.; Sánchez, D. (2008). Características nutriciona-les de la variedad Sabrosa-Candonga®. Fruticultura Profesional 175 :34-37.

Palaudelmàs, M.; Peñas, G.; Messeguer, J.; Melé, E.; Serra, J.; Salvià, J.; Pla, M.; Nadal, A. (2008). Coexistència entre blat de moro Bt i con-vencional. Dossier Tècnic. Formació i assessorament al sector agroa-limentari 27 :19-23.

35

3. O

ur d

epa

rtm

ents

annual report 2008 - cragenomica.es · environmental stress, in both biotic (attack by pathogens)...

Documents