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Conference Proceedings

26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society

EMBC

2004

LINKAGES TOR INNOVATION

IN BIOML PIC i NE

SAN FRANCISCO, USA

1-5 September 2004San Francisco, California

Volume VII

Conference Chair

Donna Hudson, Ph.D.

Program Chair

Zhi-Pei Liang, Ph.D.

Publications Chair

Guy Dumont, Ph.D.

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TIB/UB Hannover

126 450 404

89

The Time Course ofFunctional CouplingBetween Human CorticalMotorAreas duringInternally Driven Vs. Externally CuedMovements

Myers, Lance J.; MacKinnon, Colum D.

Cortical Contributions to the Stretch ReflexResponse in Biceps Brachii

Krutky, Matthew A.

Muscle Focus: a New Biomechanical-Based

Index on the Selectivity ofEMG Activity andIts

Application in Quantifying the Muscle

Coactivation Patterns during Isometric TorqueGeneration at the Elbow andShoulder

Yao, Jun; Acosta, Ana Maria; Dewald, Julius P.

A.

Abnormal Intrinsic and Reflex Stiffness Relatedto Impaired Voluntary Movement

Mirbagheri, Mehdi M.; Tsao, Cheng-Chi; Rymer,W.Z.

Modulation ofStretch Reflex Excitability duringQuiet Human StandingBock, Przemek J.; Kearney, Robert, E.; Forster,Shauna, M.; Wagner, R.

Time-Varying Parallel-cascade SystemIdentification ofAnkle Stiffnessfrom Ensemble

Data

Baker, Mackenzie J.; Zhao, Yong; Ludvig, Daniel;Wagner, Ross; Kearney, Robert E.

A DistributedModel ofthe Saccadic System:Simulations ofTrajectory Variations Produced

by Multiple Competing Visual Stimuli

Arai, Kuniharu; Keller, Edward L.

Organization ofthe Fibers in the Dorsolateral

Funiculus ofthe Cervical Spinal Cord in the Cat

Tie, Yanmei; Sahin, Mesut; Sundararajan,Nappinnai; Rane, Anand

Estimation ofTibial and Femoral 3D Linear

Accelerations during GaitTurcot, Katia; Aissaoui, Rachid; Pelletier, Michel;Hagemeister, Nicola;Parent, Gerald; de Guise, Jacques A.

MechanicalActions ofIndividual Muscles at theHuman Elbow Joint and Their Roles in

Protecting/Unloading the Ulnar CollateralLigamentPeng, Qiyu; Schafer, David; Hsu, Jason; Koh,Jason; Zhang, Li-Qun

Nonparametric Identification ofthe Elbow Joint

Stiffness under CompliantLoadsRavichandran, Vengateswaran J.; Perreault, EricJ.; Westwick, David T.; Cohen, Nathan

Track 11.9: Neurophysiology and

Clinical Applications

4669 Session 11.9.1: Clinical Neurophysiology

4673

4677

4680

4684

4688

4692

4696

4700

4704

4706

Comparison ofLine Length Feature Before and

After Brain Electrical Stimulation in

Epileptic Patients

Esteller, Rosana; Echauz, Javier; Tcheng, Tom 4710

Diffuse Electrical Injury: A Study ofSequelaeAsA Function of Gender

Morse, Jennifer S.; Morse, Michael S. 4714

EnhancedSpatio-TemporalClustering in the

Detection ofNeonatal Seizures usingContext-BasedRules

Mitra, Joyeeta; Glover, John R.; Ktonas, Periklis

Y.; Frost, Jr., James D.;

Hrachovy, Richard A.; Mizrahi, Eli M. 4717

Investigation ofLapses ofConsciousness using aTracking Task: Preliminary Results

Peiris, Malik T. R.; Jones, Richard D.; Carroll,Grant J.; Bones, Philip, J. 4721

A Comparison ofCovert and Overt Attention as a

Control Option in a Steady-State Visual Evoked

Potential-basedBrain Computer InterfaceKelly, Simon P.; Lalor, Ed; Finucane, Ciaran;Reilly, Richard B. 4725

High-Frequency Ner\>e Conduction Block

Bhadra, Niloy; Kilgore, K. L. 4729

Electrode Pressure Application andMeasurement System During CMAP Studies:

Preliminary Results.

Ezenwa, Bertram N. 4733

Clinical Evaluation ofthe Tilt Sensors Feedback

Controlled FESfor HemiplegiaYu-Luen, Chen 4737

Dorsal Column Is Not Involved in the

Mechanism ofthe Hypotensive Effect bySimulatingAcupuncture on Rat Hindlimb

Yu, Yan-Qin; Xia, Qiang; Zhang, Rong-Bao;Shan, Qi-Xian; Bruce, Iain C. 4741

Validation ofa Computer-AidedEMGDecomposition Method

McGill, Kevin C; Lateva, Zoia C; Johanson, M.Elise 4744

Melatonin Reduced Volume of Cerebral InfarctInduced by Photothrombosis in Wild-Type Mice,Not in Cyclooxygenase-1 Gene Knockout Mice

Zou, L„Y.; Liu, S. R.; Li, G.; Huang, L.; Yang,Edward S. 4748

PAM: Passive Marker-based Analyzer to TestPatients with Neural Diseases

Jobbagy, Akos; Hamar, Gabor 4751

Ix

Track 11.10: TeleRehabilitation and

Wearable Technology

Session 11.10.1: Wearable Technology in

Rehabilitation

Wearable Conductive Fiber SensorArraysforMeasuringMulti-Axis JointMotion

Gibbs, Peter T.; Asada, H. Harry 4755

Reconfigurable IntelligentSensorsforHealth

Monitoring: A Case Study ofPulse Oximeter

Sensor

Jovanov, Emil; Milenkovic, Aleksandar; Basham,Shane; Clark, Drake W.; Kelley, David A. 4759

Applications of Vibrotactile Display ofBody Tilt

for Rehabilitation

Wall, Conrad; Oddsson, Lars; Horak, Fay;Wrisley, Diane; Dozza, Marco 4763

Data Mining Techniques to Detect Motor

Fluctuations in Parkinson's Disease

Bonato, Paolo; Sherrill, Delsey M.; Standaert,David G.; Salles, Sara S.; Akay, Metin 4766

The Inflience ofFloor Material on Standing and

Walking by Hemiplegic Patients

Kuwae, Yutaka; Yuji, Tadahiko; Higashi, Yuji;Fujimoto, Toshiro; Sekine, Masaki; Tamura,Toshiyo 4770

Session 11.10.2: Tele-rehabilitation and

RemoteAssessment Techniques

An Interactive Telemedicine Systemfor Remote

Speech-Language Pathology Treatment

Brennan, David M.; Barker, Linsey M. 4773

Progress Toward Universal Interface

Technologiesfor Telerehabilitation

Winters, Jack M. 4777

AccelerometricActivity Identificationfor RemoteAssessment ofQuality ofMovementSabelman, Eric E.; Fiene, Amy; Timbie, Anna 4781

A Remote Assessment System with a Vision

Robot and Wearable Sensors

Zhang, Tong; Wang, Jue; Ren, Yumiao; Li,

Jianjun 4785

Monitoring FunctionalArm MovementforHome-Based Therapy after Stroke

Sanchez, Robert; Reinkensmeyer, David; Shah,Punit; Liu, Jiayin; Rao, Sandyha; Smith, Robert;

Cramer, Steve; Rahman, Tariq; Bobrow, James 4787

Session 11.10.3: Rehabilitation

Engineering I

A Low CostMethod to Measure FingerFlexionin Individuals with ReducedHand and FingerRange ofMotionSimone, Lisa K.; Elovic, Elie; Kalambur, Ujwala;Kamper, Derek G. 4791

Navigation Systemfor Visual ImpairedPersonsBasedon Satellital Location

Perez-Ponce, Hector; Hernandez-Rodriguez, Pablo

Rogelio 4795

A Portable Audio-Biofeedback System to ImprovePostural Control

Dozza, Marco; Horak, Fay B.; Chiari, Lorenzo 4799

Evaluation ofCommandSourcesfor a HighTetraplegia NeuralProsthesis

Williams, Matt 4803

On the Design ofan ExoskeletonforNeurorehabilitation: Design Rules and

Preliminary PrototypeCarrozza, Maria Chiara; Ng Pak, Nicola; Cattin,

Emanuele; Vecchi, Fabrizio;Marinelli, Martina; Dario, Paolo 4807

Preliminary Study on Electrotactile Sensitivity oftheLipsLiu, Wei; Tang, Hui 4811

Assessing MuscleBlood Flow Volume in ElderlyPoststrokeHemiplegic Patients Using Near-

Infrared SpectroscopyFukunaga, Seiji; Miyazaki, Tomoko; Yuj,Tadahiko; Fujimoto, Toshiro; Higashi, Yuji;Sekine, Noriko;Tamura, Toshiyo; Shiga, Toshikazu 4815

Track 11.11: New Techniques in

Rehabilitation

Session 11.11.1: Neurorobotics and

Rehabilitation

Robotic Gait Training: Toward More Natural

Movements and Optimal TrainingAlgorithmsReinkensmeyer, David J.; Aoyagi, Daisuke;Emken, Jeremy; Galvez, Jose; Ichinose, Wade;Kerdanyan, Grigor; Nessler, Jeff;

Maneekobkunwong, Sonboom; Timoszyk,Woiciech; Vallance, Kevin;

Wynne, John; de Leon, Ray; Bobrow, James;Harkema, Susan; Edgerton, Reg 4818

CooperativeStrategiesfor Robot-Aided Gait

Neuro-Rehabilitation

Riener, Robert; Ltinenburger, Lars; Colombo,

Gery 4822

Ixi

Upper and Lower Extremity Robotic Devices to

Promote Motor Recovery After Stroke - Recent

DevelopmentsSchmidt, Henning; Hesse, Stefan; Werner,

Cordula; Bardeleben, Anita 4825

Robotic-Assessment of Walking in Individuals

with Gait Disorders

Hidler, Joseph 4829

Session 11.11.2: Developing Virtual

Technology for Rehabilitation

Networked Virtual Environments and

Rehabilitation

Kenyon, Robert V.; Leigh, Jason 4832

Vestibular Rehabilitation Using a Wide Field ofView Virtual Environment

Sparto, Patrick J.; Furman, Joseph M.; Whitney,Susan L.; Hodges, Larry F.; Redfern, Mark S. 4836

Robotics and Virtual Reality: The Development

ofa Life-Sized 3-D Systemfor the Rehabilitation

ofMotor Function

Patton, James L. 4840

TheraDrive: A New Stroke Therapy PlatformforHome-based, Computer-Assisted MotivatingRehabilitation

Johnson, Michelle J.; Trickey, Megan; Brauer,

Emily; Xin, Feng 4844

Dual Stewart Platform Mobility Simulator

Boian, Rares; Bouzit, Mourad; Burdea, Grigore C;Deutsch, Judith 4848

Session 11.11.3: Applying Virtual Realityto Rehabilitation

Design and Development of Virtual Reality Based

Perceptual-Motor Rehabilitation Scenarios

Rizzo, Albert; Cohen, Issac; Weiss, Patrice L.;Kim, J. Gerry; Yeh, Shih-Ching;Zali, Baharak; Hwang, Jae-In 4852

Outcomes ofIntervention Programs usingFlatscreen Virtual RealitySveistrup, Heidi; Thornton, M.; Bryanton, C;McComas, J.; Marshall, S.; Finestone, H.;McCormick, A.; McLean, J.; Brien, ML; Lajoie,Y.; Bisson, E.

Locomotor Rehabilitation in a Complex Virtual

Environment

Fung, Joyce; Malouin, Francine; McFadyen,Bradford J.; Comeau, Francois; Lamontagne,Anouk;Chapdelaine, Sebastian; Beaudoin, Christian;Laurendeau, Denis; Hughey, Lucinda; Richards,Carol L.

4856

PosturalResearch and Rehabilitation in an

Immersive VirtualEnvironment

Keshner, Emily A.; Kenyon, Robert V.; Dhaher,Yasin 4862

Shaping Synergistic Pinching Patterns with

Feedback Distortion in a Virtual

Rehabilitation Environment

Matsuoka, Yoky; Brewer, Bambi; Klatzky,Roberta 4866

Session 11.11.4: Rehabilitation

Engineering II

Development ofthe Visually ImpairedPersonGuidance System Using GPS

Soeda, Koji; Aoki, Shingo; Yanashima, Kenji;Magatani, Kazushige 4870

Rehabilitative Orthotics Evaluation in Children

with Diplegic CerebralPalsy: Kinematics

andKinetics

Hassani, S.; Roh, J.; Ferdjallah, M.; Reiners, K.;Kuo, K.; Smith, P.; Harris, G. 4874

Simulation Study ofFES-AssistedStanding Upwith Neural Network Control

Zhang, Dingguo; Zhu, Kuanyi 4877

Optimized Joystick Controller

Ding, Dan; Cooper, Rory A.; Spaeth, Donald M. 4881

Biomechanics ofFemoral Deformity in

Osteogenesis Imperfecta (OI): A QuantitativeApproachto Rehabilitation

Fan, Z.; Smith, P.; Reiners, K.; Hassani, S.; Harris,G. 4884

Biofeedback in Gait Training with the Robotic

Orthosis Lokomat

Ltinenburger, Lars; Colombo, Gery; Riener,Robert; Dietz, Volker 4888

Real-Time Head MovementSystem and

EmbeddedLinux Implementationfor the Control

ofPower Wheelchairs

Nguyen, Hung T.; King, Leslie M.; Knight, Glenn 4892

Measurement ofAnkle Spasticity in Children

with Cerebral Palsy Using a Manual

Spasticity Evaluator

Peng, Qiyu; Shah, Parag; Selles, Ruud W.;Gaebler-Spira, Deborah J.; Zhang, Li-Qun 4896

Development ofthe Navigation SystemforVisually ImpairedHarada, Tetsuya; Kaneko, Yuki; Hirahara,Yoshiaki; Yanashima, Kenji; Magatani,Kazushige 4900

4859

Ixii

Generic InputDevicefor Basic Control and

Configuration oftheMultipleMaster MultipleSlave SystemChen, Chiun-fan; Chang, Yi-chu; Chen, Heng-Yin;Lai, Jin-shin; Chong, Fok-ching 4904

Diagnosis and Rehabilitation ofPatients with

HemispatialNeglect Using Virtual

Reality TechnologyBaheux, Kenji; Yoshizawa, Makoto; Tanaka,Akira; Seki, Kazunori; Handa, Yasunobu 4908

Development ofthe WalkingSupportRobot with

the Weight Bearing Mechanism SupportingIschia-Cushionfor Ischia and Behavior oflschia

during WalkingKuroko, Shiho; Fujie, Masakatsu G.; Takashima,

Takamichi; Takeuchi, Ikuo 4912

Quantification ofReaching During Stroke

Rehabilitation Using a Unique UpperExtremityKinematicModel

Hingtgen, Brooke A.; Harris, Gerald F.; Wang,Mei; McGuire, John R. 4916

A Mobile Toolfor Accessibility and Usability

Testing ofMedicalInstrumentation

Lemke, Melissa R.; Winters, Jack M.; Danturthi,

Sarma; Campbell, Sean; Follette Story, Molly;Barr, Alan; Rempel, David M. 4920

Analysis ofImpulseResponse on Walking

Stability using Accelerometers

Tsuruoka, Masako; Tsuruoka, Yuriko; Shibasaki,

Ryosuke; Yasuoka, Yoshifumi; Murai, Shunji 4924

The Mechanomyogram as a Channel ofCommunication and Controlfor the Disabled

Nolan, Yvonne M.; dePaor, A. 4928

Enhanced TheraJoy Technologyfor use in

Upper-Extremity Stroke Rehabilitation

Johnson, Laura M.; Winters, Jack M. 4932

Virtual Reality Based Rehabilitation ofHandFunction after Stroke: Transfer to Function

Adamovich, S. V.; Merians, A. S.; Boian, R.;

Tremaine, M; Burdea, G. S.; Recce, M.; Poizner,H. 4936

A Text InputSystem Developed by Using Lips

Image Recognition Basedon LabVIEWfor The

Serious Disabled

Chen, Shih-Chung 4940

Three-Dimensional DynamicalMeasurement of

Upper Limb Support duringParaplegic WalkingHu, Yong; Ming, Dong; Wang, Y. Z.; Wong, Y.

W.;Luk,K.D.K.;Leong,J.C.Y, 4944

Sensory Substitution System ofTwo-Channel

Electrotactile Stimulationfor TransmittingVerbal InformationKim, G.; Okuno, R.; Yoshida, M.; Akazawa, K. 4948

Development ofthe Assist System to Operate a

Computerfor theDisabled Using Multichannel

Surface EMG

Nagata, Kentaro; Yamada, Masafumi; Magatani,Kazushige 4952

4964

Development ofAutomatic Immediate FittingSocket SystemforArtificial Leg Socket Modeling

using Fuzzy Control

Nakamura, Kouhei 4956

Development ofa Piezoelectric ActuatorforPresentation of Various Tactile Stimulation

Patterns to Fingerpad Skin

Homma, Takeshi; Ino, Shuichi; Kuroki, Hayato;Izumi, Takashi; Ifokube, Tohru 4960

Theme 12. Molecular, Cellular and

Tissue Engineering and

Biomechanics

Track 12.3: Cellular Engineering

Session 12.3.1: Cell Engineering

Using Mkroenvironment to Engineer Stem Cell

Function

Chen, Christopher S.

QuantitativeAnalysis ofSignaling Mechanisms

ControllingAdultNeuralProgenitorCellProliferationSchaffer, David V,; O'Neill, Analeah; Hochrein,

Lisa; McGranahan, Tresa

Tissue Engineering ofMuscle on MicropatternedPolymer Films

Huang, NganF.; Thakar, Rahul G.; Wong,Maelene; Kim, Daniel; Lee, Randall J.; Li, Song

The Topographical Guidance ofNeurons

cultured on Photo-ResponsivePolymerLee, Jae Kyoo; Baac, Hyoungwon; Song, Sang-Ho; Lee, Sin-Doo; Park, Dongeun; Kim, SungJune

Kinetics ofLFA-1 Binding to ICAM-1 Studied in

a Cell-Free SystemSarantos, MelissaR.; Lum, Aaron F. H.; Staunton,Donald E.; Simon, Scott I.

SimulatingLeukocyte-Venule Interactions -A

NovelAgent-OrientedApproachTang, Jon; Hunt, C. Anthony; Mellein, Jason; Ley,Klaus

4965

4966

4970

4974

4978

Ixiii

Session 12.3.2: Molecularand Cell

Engineering and Biomaterials

Polarization-modulatedSecond Harmonic

Generation Imaging: A Novel MethodforQuantitative Assessment ofDisorganization in

Anulus Fibrosus

Knoesen, Andre 4982

Spectroscopic Studies ofMitochondrialNADH

FluorescenceSignals in Brain Slices

Qiu, Liqun; Zhao, Weizhao; Sick, Thomas 4986

Study ofthe Effects of50Hz HomogeneousMagnetic Field on Apoptosis andProliferation ofSNU Cells In Vitro

Guo, Hongyong; Zheng, Mo; Xing, Lingxiao; Li,

Ying; Ge, Manling; Zhang, Xianghong; Yan,Weili 4990

Inactivation ofAtmospheric Bacteria Using LyticEnzyme Mixture

Yamaguchi, Masaki; Tahara, Yusuke; Deguchi,Mitsuo; Arai, Jun-Ichiro 4994

Challenges in Capillary Pressure MicroinjectionKuncova, Johana; Kallio, Pasi; 4998

Development ofa Computational ModelforCellularPacemaking in the Gastrointestinal

SystemFaville, Richard A.; PuIIan, Andrew; Smith,Nicolas P. 5002

Lethal andInhibitory Effects ofSteep PulsedElectric Field on Tumor-Bearing BALB/c MiceMi, Yan; Sun, Caixin; Yao, Chenguo; Xiong, Lan;Liao, Ruijin; Hu, Ya; Hu, Lina 5005

Vascular Effect and Immunity Effect ofSteepPulse Electric Field on Walker 256-bearingWistar Mice

Xiong, Lan; Sun, Caixin; Yao, Chenguo; Mi, Yan;Wang, Shibin; Luo, Xiaodong; Hu, Lina 5009

Long-Term Stability ofPlasma Oxidized PDMSSurfacesKim, Bongsu; Peterson, Erik T. K.; Papautsky,Ian 5013

Multiple Volume Injection Techniquefor High-Resolution DNA Sample Detection UtilizingPlanar Microfluidic ChipChang, Guan-Liang 5017

Track 12.4: Tissue Engineering

Session 12.4.1: Tissue EngineeringBiomimetic Scaffoldsfor Tissue EngineeringBhatnagar, Rajendra S.; Li, Song 5021

Mechanical Regulation ofMatrix ReorganizationandPhenotype ofSmooth Muscle Cells and

Mesenchymal Stem Cells in 3D Matrix

Liao, Sophia W.; Hida, Kaoru; Park, Jennifer S.;Li, Song 5024

Synthetic Peptides Cytomodulin-1 (CM-1) andCytomodulin-2 (CM-2) Promote CollagenSynthesis and Wound Healing in Vitro

Lam, Hayley J.; Li, Song; Lou, Nweni; Chu, JuliaS.; Bhatnagar, R.

5023

The Necessity ofa Theory ofBiologyfor Tissue

Engineering: Metabolism-Repair SystemsGanguli, Suman; Hunt, C. Anthony 5031

Track 12.5: Biomaterials for Tissue

Engineering

Session 12.5.1: Biomaterials for TissueEngineering

Control ofCell Function with Tunable HydrogelNetworks

Healy, Kevin E. 5035

Molecularly EngineeredHydrogelsfor ImplantBiocompatibilityGuiseppi-Elie, Anthony; Brahim, Sean; Abraham,Sheena 5036

Endothelial Cell Function on a Poly(acrylamide-Co-Polyethylene Glycol/acrylic Acid)Interpenetrating Polymer Network:Cardiovascular ApplicationsPatel, Shyam H.; Tsang, Jonathan; Harbers, Greg;Healy, Kevin E.; Li, Song 5040

The Attachment, Proliferation, and Wound

Healing ofEndothelial andSmooth Muscle Cells

on Nitinol Thin Film in Vitro

Lam, Hayley J.; Li, Song; Leong, Isabel P. L.;Menchaca, Leticia; Johnson, A. D. 5044

A Drug Delivery Systemfor the Treatment ofPeripheral Nervous System InjuriesCaneva Soumetz, Federico; Giacomini, Mauro;Phillips, James B.;Brown, Robert A.; Ruggiero, Carmelina 5047

Mechanical Properties ofBone-ImplantInterface: an in Vitro Modelfor the ComparisonofStability Parameters Affecting Various Stagesduring Osseointegrationfor Dental ImplantPan, Li-Chern 5050

Ixiv

Track 12.6: Biomechanics Session 12.6.3: Biomechanics

Session 12.6.1: Vascular Biomechanics

Cyclic Stretch Increases VEGFExpression in

Pulmonary ArterialSmoothMuscle Cells Via

TGF-? I andReactive Oxygen Species: a

Requirementfor Nad(P)h Oxidase

Black, Stephen M.; Mata-Greenwood, Eugenia;Grobe, Albert; Noshkina, Yelina

Sickle Cell Blood Flow in the Microcirculation

Berger, Stanley A.; Carlson, Brian E.

MechanicalProperty Characterization oftheZebrafish Chorion

Kim, Deok-Ho; Sun, Yu; Yun, Seok; Kim,Byungkyu; Hwang, Changnam;Lee, Sangho; Nelson, Bradley J.

Modulation ofATP/ADP Concentration at the

Endothelial Surface by Shear Stress: Effect ofFlow Disturbance

Choi, H. W.; Barakat, A. I.

Dynamic Deformation Capability ofaRed Blood

Cell under a Cyclically ReciprocatingShear Stress

Watanabe, Nobuo; Yasuda, Toshitaka; Kataoka,Hiroyuki; Takatani, Setsuo

Preliminary Look at Why Some Vessels Get

Atherosclerosis and OthersDon't

Rumschitzki, David; Shou, Y.; Jan, K. M.

Session 12.6.2: Tissue Biomechanics

Stress Analysis ofUnilateral CleftPalate Using a

Three Dimensional Finite ElementModel ofPediatric Subject-Specific Maxilla

Zhao, Linping; Patel, P. K.; Harris, G. F.

Development ofa Three-Dimensional Finite

Element Model ofBreast Mechanics

Rajagopal, V.; Nielsen, P. M. F.; Nash, M. P.

The Effect ofHormone Treatment on the Plastic

Characteristic ofOsteoporotic Vertebral

Trabecular Bone

Woo, Daegon; Kim, Hansung

A Subject-Specific FEMModelfor EvaluatingButtock Tissue Response under Sitting LoadLin, Fang; Moran, Brian; Bankard, James;Hendrix, Ronald; Makhsous, Mohsen

Loading Conditions and Bone Formation in the

GHRegion ofthe Shoulder

Lim, Dohyung; Seliktar; Rami; Farrell, Eric; Tom,James; Nunes, Linda; Sun, Wei; Wee, Jinyoung

5053

5057

5061

5065

5069

5073

5077

5080

5084

5088

5092

Investigating Stress-Strain Properties ofin-vivoHuman Skin using Multiaxial LoadingExperiments and Finite ElementModelingKvistedal, Yme A.; Nielsen, Poul M. F. 5096

Kinematic Analysis of UpperExtremity Joint

Motion in Children UsingPosterior Walkers

Baker, Kelly M.; Lu, Lucy; Klein, John P.; Cao,Kevin; Reiners, Kathy; Johnson, Charlene;Lipsey, Jim; Hassani, Sahar; Ackman, Jeffrey D.;Schwab, Jeffrey P.; Harris, Gerald F. 5100

Motion AnalysisBasedon a Multi-Segment FootModel in Normal WalkingHwang, Sungjae; Choi, Huiseok; Kim, Youngho 5104

Biomechanics ofthe Double RockerSole Shoe-Gait Kinematics andKinetics

Long, Jason T.; Sirota, Nicole M.; Klein, John P.;Wertsch, Jacqueline J.; Janisse, D.; Harris, Gerald

F. 5107

Reducing Whole-Body Vibration ofVehicleDrivers with aNew Sitting ConceptLin, Fang; Crowther, Zack; Makhsous, Mohsen 5111

Solid Modeling ofHuman Vocal Tract usingMagnetic Resonance Imaging and

Acoustic PharyngometerTameem, Hussain Z.; Mehta, Bhavin V. 5115

Theme 13. Professional Activities

Track 13.1: Medical Device Excellence

Award Winners

Session 13.1.1: Medical Device

ExcellenceAward Winners

MedicalDevice ExcellenceAward Winners

Munzner, Robert F. 5119

Track 13.2: Innovations in Industry

Session 13.2.1: Biomedical Optics

Vision Correction with Excimer Lasers

Turnquist, David V. 5120

Bactericidal LightHarris, David 5121

Ophthalmic Glucose Monitoring using

Disposable Contact Lenses

Geddes, Chris 5122

Centerfor Biophotonics Science and Technology(CBST)Chuang, Frank 5123

Ixv

New Methodsfor Automated Phenotyping ofComplex Cellular Behavoirs

Garakani, Arman M.; Hack, Andrew A.; Alhouse,Jenny; Roberts, Peter G. 5124

Session 13.2.2: ComputerAssisted

Detection Commercialization

Commercialization ofComputer Assisted

Detection: The Pathfrom Science to Product

Menhardt, Wido 5127

Session 13.2.3: RFApplications

RFAblation ofIntestinal Metaplasia (BarrettEsophagus)Jackson, Jerome 5128

Session 13.2.4: BioMEMS

BioMEMs

Gross, Brooks A. 5129

Session 13.2.5: From Concept to Exit

Strategies

From Concept to Exit Strategies - Medical

Device Innovation:

Kermit, Eben L. 5130

Session 13.2.6: Commercialization of

Medical Devices

Business Models and Leadership Styles in Small

MedicalDevice and Bio-Science Businesses -

Examples in a Region and TheirImplicationsWilliams, David J,; Hourd, Paul C. 5131

Track 13.3: Best Practices in the

Medical Device Industry

Session 13.3.1: Design and Execution of

Clinical Trials

Design and Execution ofClinical StudiesforMedical Devices

Bartoo, Grace T. 5135

Session 13.3.2: Getting Your Device

Cleared by FDA

Getting Your Medical Device ClearedforMarketing in the U.S.

Bartoo, Grace T.; Munzner, Robert 5136

Session 13.3.3: Meetings with the FDA

Meetings with the FDA

Munzner, Robert F.; Bartoo, Grace 5137

Session 13.3.4: Industry Careers for theBiomedical Engineers

Industry Careers for the Biomedical EngineerMunzner, Robert F.

5138

Session 13.3.5: Technology Transfer

Technology TransferKim, Yongmin 5139

Session 13.3.6: FDA Rules forR&D

FDA Rulesfor R&D also: Root Cause Analysis& Failure InvestigationsMeyer, Gregory A. 5140

Theme 14. Education

Track 14.1: Teaching Methods

Session 14.1.1: Teaching & Research in

Biomedical Engineering

Development ofEducational Tools to

Demonstrate the Effects ofHyper and

Microgravity on Different Test Bodies

Russomano, Thais; Rizzatti, Mara R.; Coelho,

Rodrigo P.; Souza, Joao A. V. de;Wasiliew, Cristiane E.; Falcao, Felipe P; Azevedo,Dario F. G. de; Scolari, Luis M. 5141

Graphic-User-Interface Systemfor People with

Severely Impaired Vision in Mathematics Class

Sribunruangrit, Nitiphan; Marque, Catherine;

Lenay, Charles; Gapenne, Olivier

Experience with the First Three Years ofanAcceleratedDual-Degree Program in

BiomedicalEngineeringChristensen, Douglas; Horch, Kenneth

5145

5149

An Overview ofthe Integrated Laboratory Course

ofPhysiological Sciences atZhejiang Universityin China

Shan, Qi-Xian; Xia, Qiang; Lu, Yuan; Chen, Ji-

Qiang; Hu, Ai-Ping; Luo, Jian-Hong 5152

Empowering Biomedical EngineeringUndergraduates to Help Teach DesignAllen, Robert A.; Tam, William; Shoukas, Artin

A. 5154

The Universe ofActivity That Is BioengineeringResearch

Cohn, Theodore E. 5158

Ixvi

Track 14.2: Computers in Teachingand Research

Session 14.2.1: SPECIAL SESSION:

Computers and Computational Tools in

BME Education and Research

Interactive/Demo

IRiS: An Interactive Reality Systemfor BreastSelf-Examination TrainingOikonomou, Andreas; Amin, Saad A.; Naguib,RaoufN. G.; Todman, Alison G.; Al-Omishy,Hassanein 5162

Building Interactive Simulations in a Web PageDesign ProgramKootsey, J. Mailen 5166

An InteractiveElectrophysiology TrainingResourcefor Simulation-Based Teaching and

LearningDemir, Semahat S. 5169

Medical Imaging Curriculum Development: an

Interactive Simulation Systemfor

Different Modalities

Wu, Dawei; Dikshit, Aditya; Zhao, Weizhao 5172

Porting Genesis to Simulink

Rodriguez Campos, Francisco; Enderle, John D. 5176

Bridging Biomedical Basics with Practical

Applications in BME Laboratory EducationGiuffrida, Joseph P. 5180

Track 14.3: Best Practices

Session 14.3.1: Best Practices in

Promoting the BME Profession

Upgrading the Biomedical EngineeringUndergraduate Curriculum Based on Current

Trends in Higher Education

Kontodimopoulos, Nikolaos; Cavouras, Dionysios;Kandarakis, Ioannis; Spyropoulos, Vassilios;Patsavoudi, Evagelia; Ventouras, Errikos Chaim 5184

The Importance ofMultidisciplinary Teams In aLarge BiomedicalResearch ProgramMartino, Robert L. 5188

Maxi Program at IEEE EMBS Student Club of

Beijing University ofPostsand Telecommunications

Wu, Yunfeng; Tao, Ningning; Tang, Luxian; Ma,Xu; Garcia, Gonzalo A.; Mitsui, Mie 5192

Biomedical Engineering Chapters and Student

Societies: a UK and Republic ofIreland

PerspectiveJames, Christopher J.; Gibson, Oliver J. 5196

5209

5210

Determination ofthe Core Undergraduate BMECurriculum -the 1ststep in a Delphi StudyGatchell, David W.; Linsenmeier, Robert A.;Harris, Thomas R. 5200

A Code ofBioethicsforPromoting BiomedicalEngineeringMonzon, Jorge E. 5202

New Continuing Education ProgramsforHospital and Clinical EngineeringAzpiroz-Leehan, Joaquin; Urbina, Gerardo;Cadena, Miguel 5205

Track 14.4: Funding Opportunities

Session 14.4.1: SPECIAL SESSION:

Funding and Research Opportunities in

Bioengineering

Directions in Biomedical Research: The NIH

RoadmapSwaja, Richard E, 5208

Biomedical Imaging Research Opportunities at

the NIH

Haller, John

Research Opportunities in Biomaterials and

Tissue EngineeringKelley, Christine

Science andEngineering Research Opportunitiesat the NationalScience Foundation

Demir, Semahat S. 5211

Novel EngineeringApproaches to Obesity,Overweight, andEnergy Balance: Public Health

Needs and Research OpportunitiesBaldwin, John T.; Ershow, Abby; Hill, James O. 5212

Novel EngineeringApproaches to Obesity,Overweight, andEnergy Balance: Public Health

Needs and Research OpportunitiesHill, James O. 5215

Track 14.5: EMBS DistinguishedLecture Series

Session 14.5.1: Distinguished Lecturer

Series: Yongmin Kim

Electronic House Calls: High-Tech Medicine at

Your DoorstepKim, Yongmin 5216


Series: Jaako Malmivuo

Bioelectromagnetism - Relative Merits ofElectric

and Magnetic Measurements in Cardiac Studies

Malmivuo, Jaakko A. 5217

Ixvii


Series: Michael Neuman

Microfabricated Sensorsfor Biomedical

ApplicationsNeuman, Michael R. 5218

Theme 15. Mini-symposia

Track 15.1: Functional Neuroimaging

Session 15.1.1: MINI-SYMPOSIUM:

Functional Neural Imaging

Contrast Mechanisms andAcquisition Methods

in FunctionalMRI

Noll, Douglas C. 5219

Diffusion Tensor Imaging: Techniques andClinicalApplicationsZhou, Xiaohong Joe 5223

ExperimentalDesign and Analysis in Functional

MRI

Talavage, Thomas M. 5226

Arterial Spin Labelingfor QuantitativeFunctionalMRI

Hemandez-Garcia, Luis 5230

FunctionalBrain Imaging With BOSS FMRI

Miller, Karla L.; Hargreaves, Brian A.; Lee,Jongho; Ress, David;deCharms, Christopher; Pauly, John M. 5234

Track 15.2: Molecular Imaging


Molecular Imaging

Non-InvasiveAssessment ofTumor ProliferationUsing Triple Quantum Filtered 23na MRI:

Technical Challenges and Solutions

Boada, Fernando E,; Tanase, C; Davis, D.;Walter, K.; Torres-Trejo, A.; Couce, M.;Hamilton, R.;Kondziolka, D.; Bartynski, W.; Lieberman, F. 5238

A Nanotechnology-BasedAnalog ofMonoclonalAntibodiesfor Targeted Delivery ofDiagnosticand Therapeutic AgentsWiener, E. C; Pamidighantam, B.; Narayanan, V.

V. 5242

Efficiency ofTransfaction andLocalization ofSuperparamagnetic Iron Oxide Particles in

Neural Progenitor Cells Using Two Methods

Flexman, Jennifer A.; Minoshima, Satoshi; Kim,Yongmin; Miyoshi, Sosuke; Cross, Donna J.;Maravilla, Kenneth; Anzai, Yoshimi 5246

Toward Imaging the DynamicActin-MyosinInteraction using a Wet-Cell C-modeNear-Field

Optical Microscope.Stitt, J. P.; Tutwiler, R. L.; Gopalan, V.; Larrson,L. 5250

Engineering Lanthanide Complexes with

Controlled Water Exchange Ratesfor MagneticResonance ImagingWoods, Mark; Sherry, A. Dean 5254

Track 15.3: Advances in Medical

Infrared Imaging


Thermal Texture Mapping (TTM)

Clinical Study on Using Thermal Texture Mapsin SARSDiagnosisWang, Wei; Zeng, Yi; Ma, Daqing; Jin, Zhengyu;Wu, Hao; Yuan, Chunwang; Yuan, Yun-er;Liu, Zhongqi; Wang, Chen; Qi, Hairong 5258

The Study About the Temperature Distributing ofthe SphereGuo, Daofeng; Wang, Jiasen; Liu, Zhongqi 5265

Fundamental Theoretic Research of Thermal

Texture Maps ISimulation andAnalysis oftheRelation between the Depth ofInner Heat Source

andSurface TemperatureDistribution in

Isotropy Tissue

Zhi-Gang, Shang; Guo-Tai, Jiang 5271

A Circuit Simulating Methodfor Heat

Transferring in Human Body Mechanism

Guotai, Jiang; Tintin, Qu; Zhigang, Shang;Xiaoyan, Zhang 5274

Study of Trilogy-imaging Characteristics on

TTM and its Relationship with MalignanciesZhou, Yulin; Chen, Xi; Yu, Wen; Yu, Jidong;Wang, Hongling; Zhang, Naihe; Bi, Hongxin 5277

Re-Investigation ofthe Mechanism ofTrilogyImaging Characteristics on TTM in Cancer

Patients

Zhou, Yulin; Chen, Xi; Yu, Wen; Yu, Jidong;Jiang, Jingsong; Wang, Hongling; Zhang, Naihe 5280

Evaluation ofLow-Intensity Laser External

Radiotherapy through Thermal Texture Mapping(TTM) TechnologyLi, Z. R.; Liu, S. H.; Zhao, Y. P.; Zeng, C. C;Wang, X. J. 5282

Ixviii

Track 15.4: Biophontonics andBiomedical Optical Imaging


Biophotonics and Biomedical OpticalImaging

Coherent Backscattering Spectroscopy: A NewTechniquefor Tissue DiagnosisKim, Young; Liu, Yang; Backman, Vadim 5285

Development ofA Fast ScanningMiniatureProbe andMethods ofDispersion Managementfor High-resolution Optical Coherence

TomographyLi, Xingde; Liu, Xiumei; Chen, Yuchuan; Cobb,Michael J.; Kimmey, Michael B. 5289

Molecular Imaging ofCarcinogenesis with

Immuno-TargetedNanoparticlesSokolov, Konstantin V.; Aaron, Jesse; Mack,Vivian; Collier, Tom; Coghlan, Lezlee;Gillenwater, Ann; Adler Storthz, Karen; Follen,Michele; Richards Kortum, Rebecca 5292

Visualizing Early Frog Development with

Motion-Sensitive 3-D Optical Coherence

MicroscopyHaskell, R. C; Williams, M. E.; Petersen, D. C;Hoeling, B. M.; Schile, A. J.; Pennington, J. D.;Seetin, M. G.; Castelaz, J. M.; Fraser, S. E.; Papan,C; Ren, H.; de Boer, J. F.; Chen, Z. 5296

Pulse Shaping StrategiesforNonlinearInterferometric VibrationalImaging Optimizedfor Biomolecular ImagingMarks, Daniel L.; Vinegoni, Claudio; Bredfeldt,Jeremy S.; Boppart, Stephen A, 5300

SecondHarmonic Optical Coherence

TomographyChen, Zhongping; Jiang, Yi; Tomov, Ivan; Wang,Yimin 5304

Track 15.5: BioelectromagneticImaging


Bioelectromagnetic Imaging

High-Resolution Ultrasound-AidedBiophotonicImagingWang, Lihong V.; Wang, Xueding; Ku, Geng; Xie,Xueyi; Stoica, George 5307

Multimodal Integration ofEEG and Functional

Magnetic Resonance RecordingsBabiloni, F.; Babiloni, C; Carducci, F.; Rossini,P.; Basilisco, A.; Astolfi, L.; Cincotti, F. 5311

MR Current Density and Conductivity Imaging:The State ofthe Art

Joy, Michael L. G. 5315

Three-Dimensional ElectrocardiographicImagingHe, Bin 5320

Track 15.6: Recent Progress in Neural

Engineering

Session 15.6.1: MINI-SYMPOSIUM: RecentAdvances in Neural EngineeringSimultaneous Prediction ofFour Kinematic

Variablesfor a Brain-Machine Interface Using a

Single Recurrent Neural Network

Principe, Jose; Sanchez, J. C; Carmena, J. M.;Lebedev, Mikhail; Nicolelis, M. A. L. 5321

Neural InterfacingThakor, Nitish; Sarje, Anshu 5325

NeuralInterfacing with the PeripheralNervousSystemDurand, Dominique M.; Yoo, Paul; Lertmanorat,Zeng 5329

FunctionalNear-infrared NeuroimagingIzzetoglu, Kurtulus; Bunce, Scott; Izzetoglu,Meltem; Onaral, Banu; Pourrezaei, Kambiz 5333

Track 15.7: Neural Interfacing


Electronic Interfaces to In-Vitro Neural

Networks

Patterning to Influence in Vitro Neuronal

InterfacesWheeler, Bruce C; Nam, Yoonkey; Brewer,Gregory J. 5337

Computation Within CulturedNeural Networks

DeMarse, Thomas; Cadotte, Alex; Douglas,Pamela; He, Penny; Trinh, Vinh 5340

Session 15.7.2: MINI-SYMPOSIUM: Brain-

Machine Interfacing

ImplantableNeural Probe Systemsfor Cortical

NeuroprosthesesKipke,DarylR. 5344

Multisite MicroelectrodeArraysforMeasurements ofMultiple NeurochemicalsBurmiester, J.; Coates, Jr., Thomas D.; Gerhardt,G.A. 5348

RecordingAdvancesfor NeuralProstheticsAndersen, Richard A.; Burdick, Joel W.;Musallam, Sam; Scherberger, Hans; Pesaran,

Ixix

Bijan; Meeker, Daniella; Cornell, Brian D.;Fineman, Igor; Nenadic, Zoran; Branchaud, Eddie;Cham, Jorge G.; Greger, Bradley; Tai, Yu-Chong;Mojarradi, Mohammad M. 5352

Track 15.8: System Theory in

Industrial Patient Monitoring: AnOverview


System Theory in Industrial Patient

Monitoring: Presentations & Panel

Discussion

System Theory in Industrial Patient Monitoring:An Overview

Baura, Gail 5356

Continuous Measurement ofCardiac OutputUsing Stochastic System IdentificationTechniquesYelderman, Mark 5360

Adaptive Filtering andAlternative CalculationsRevolutionizes Pulse Oximetry Sensitivity and

Specificity during Motion and Low PerfusionGraybeal, John; Petterson, Mike 5363

Track 15.9: Mobile Telhealthcare

Session 15.9.1: MINI-SYMPOSIUM: Mobile

Telehealth

ProposedFramework to Measure the ROI ofMobile Tele-Health Solutions in the

Management ofChronic DiseasesLacal, Jose C.

Advances in Robotic Tele-Echography Services -The OTELO SystemCourreges, Fabien; Vieyres, P.; Istepanian, R. S.

H.

Delivering Low-Bandwidth TelemedidneSenices Over HybridNetworks In DevelopingCountries

Dahlgren, Robert P.; Amble, R.; Comparini, A.;Kumar, K. R.; Lurie, Y. M.

5367

5371

5375

Track 15.10: Wearable Sensors andDevices for Tele-Home Healthcare

Session 15.10.1: MINI-SYMPOSIUM:Wearable Sensors and Devices for Tele-home Healthcare

Cable-Free Wearable Sensor System Using a DCPowerline Body Network in a Conductive

Fabric Vest

Wade, Eric R.

Development ofReusable and ExpandableCommunication Platformfor Wearable MedicalSensor Network

Park, D. G.; Kang, S. W.

Wearable Medical Devicesfor Tele-Home

Healthcare

Hung, Kevin; Zhang, Yuan-Ting; Tai, Bun

Extracting Breathing Rate Informationfrom a

Wearable Reflectance Pulse OximeterSensorJohnson, W. S.; Mendelson, Yitzhak

5376

5380

5384

5388

Track 15.11: Biomolecular Processorsthrough Micro- and Nanotechnology

Session 15.11.1: MINI-SYMPOSIUM:Biomolecular Processors through Micro-and Nano-technology

DigitalMicrofluidicsfor Bioassays and DrugDelivery!Lee, Abraham P.

The Needfor Cellular andMolecularSensorsandActuators

Wikswo, John P.

IntegratedMicrofluidic BiochipsforImmunoassay andDNA BioassaysLiu, Robin H.

Microdevicesfor Biomolecular DetectionManalis, Scott R.

Track 15.12: Issues in Nonlinear

Analysis of Biosignals

Session 15.12.1: MINI-SYMPOSIUM:Issues in NonlinearAnalysis of

Biosignals

Diagnostic Potential ofNonlinearAnalysis ofBiosignalsCohen, Maurice E.; Hudson, Donna L.

5392

5393

5394

5395

5396

Ixx

Nonlinear Methodsfor Biopattern Analysis: Roleand ChallengesIfeachor, Emmanuel C; Outram, N. J.; Henderson,G. T.; Wimalaratna, H, S. K; Hudson, N.; Sneyd,R. 5400

Nonlinear Analysis ofHeart Rate VariabilitySignal: PhysiologicalKnowledge and

Diagnostic Indications

Signorini, Maria G. 5407

Track 15.13: The Global PhysiomeProject and Standards for Model

Representation

Session 15.13.1: MINI-SYMPOSIUM: TheGlobal Physiome Project and Standardsfor ModelRepresentation

The Evolution ofCellMLNielsen, Poul F.; Halstead, Matt D. 5411

The Foundational Model ofAnatomy: a

Templatefor the Symbolic Representation ofMulti-Scale Physiological Functions

Cook, Daniel L.; Mejino, J. L. V.; Rosse, C. 5415

AFL and FRL: Abstraction and Representationfor FieldInterchangeTsafhat, Guy; Cloherty, Shaun; Lambert, Tim 5419

Track 15.14: Applications of

Radiofrequency to Tissue Ablation


Applications of Radiofrequency to Tissue

Ablation

Training Strategiesfor the UserInterface ofVocationalAssistive Robots

Wagner, James J.; Van der Loos, Machiel 5423

Radio Frequency Conductive Keratoplasty in theCornea: Prediction ofDiopter Changes in

Numerical Models

Pearce, John A.; Panescu, Dorin 5426

Intra-Operative RFAblation in theAtria

Swanson, David K.; Panescu, Dorin 5430

Hepatic Radiofrequency Ablation - an Overview

from an Engineering PerspectiveHaemmerich, Dieter 5433

Track 15.15: Tissue Injury by ElectricalForces: Thermodynamic Mechanismsand Pathophysiological Manifestations


Tissue Injury by Electrical Forces:

Thermodynamic Mechanisms and

Pathophysiological Manifestations

Neurological Manifestations ofElectricalTrauma

Ryan, Colleen 5437

Stability ofCellularProteins underSupraphysiological TemperaturesDespa, Florin; Orgill, D. P.; Lee, R. C. 5440

Electroporation ofa Multicellular System:Asymptotic ModelAnalysisWeaver, Jim C; Gowrishankar, T. R.;Stewart, Chip 5444

Subcellular Effects ofNanosecondElectricalPulses

Schoenbach, Karl; Joshi, Ravindra; Kolb, J,;

Buescher, Stephen; Beebe, Stephen 5447

Magnetic Resonance Imaging ofMuscle

Electroporation InjuryLee, Raphael C; Despa, F.; Collins, J. C;Karczmar, G.; Tenchov, B. 5451

Theme 16. Keynote Speaker

Track 16.1: Opening Ceremony &

Keynote Lecture: Paul C. Lauterbur

Session 16.1.2: Plenary Lecture: Savio L-

Y. Woo

Contribution ofBiomechanics to Clinical

Practice in OrthopaedicsWoo, Savio L-Y. 5455

Session 16.1.3: Plenary Lecture: DouglasLauffenburger

Biological Engineering & Systems Biology -New Opportunitiesfor EngineersIn the

PharmaceuticalIndustryLauffenburger, Douglas A. 5456

Session 16.1.4: Awards Banquet &

Keynote Lecture: Peter Katona

Biomedical Engineering: A Field on the Move

Katona, Peter 5457

Ixxi

Session 16.1.5: Plenary Lecture: ShankarSubramaniam

Bioinformatics and Computational SystemsBiology: At the Cross Roads ofBiology,Engineering and ComputationSubramaniam, Shankar 5458

Mechanobiology In IntervertebralDisc

Degeneration andRegenerationLotz, J.C; Staples, A,; Walsh, A.;Hseieh, A.H. 5459

Ixxii

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