INTERNATIONA1 S SYMPOSIUM

TABLE OF CONTENTS

Page

PROGRAM 1

SESSION 1 17

SESSION 2 18

SESSION 3 24

SESSION 4 30

SESSION 5 35

SESSION 6 40

SESSION 7 46

SESSION 8 52

SESSION 9 53

SESSION 10 59

SESSION 11 65

SESSION 12 66

SESSION 13 71

SESSION 14 76

SESSION 15 77

SESSION 16 83

SESSION 17 89

SESSION 18 94

SESSION 19 99

SESSION 20 106

SESSION 21 113

SESSION 22 114

SESSION 23 120

SESSION 24 126

SESSION 25 131

SESSION 26 136

SESSION 27 141

ADDENDUM 147

AUTHOR INDEX 187

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Session 1

KEYNOTE SESSION

CLINICAL EVALUATION OF RESTORATIVE

MATERIALS

Session Chairman — C. W. HALL, South West Research Institute,San Antonio, TX, USA

8:00 Welcome: F. W. Cooke, Symposium Chairman.

8:05 Opening Remarks: J. L. Katz, President, Society For Biomaterials.

8:10 Tutorial Address: "Good Laboratory Practices: The Law". R. R. Stromberg, Device

Research Testing, Biomedical Devices, F.D.A., Washington, DC, USA.

9:00 Keynote Address: "Clinical Evaluation of Restorative Materials". I. A. Mj5r, Scan¬dinavian Institute of Dental Materials, Oslo, Norway.

Session 2DENTAL RESTORATIVE MATERIALS

Session Chairman — J. A. TESK, National Bureau of Standards,

Washington, DC, USA

10:20 Effects of Microstructure on Compressive Fatigue of Dental Composite Restorative

Materials. R. A. Draughn, Medical Univ. of South Carolina, Charleston, SC, USA

10:40 Identification of Corrosion Products in Dental Amalgams. S. J. Marshall and G. W.

Marshall, Departmentof Biological Materials Northwestern Univ., Chicaqo, IL, USA

11:00 In Vitro Measurement of the Corrosion Resistance of Dental Amalgams. M. Marek,

School of Chemical Engineering, Georgia Inst, of Tech., Atlanta, GA, USA

11:20 Volume Fractions of Phases and Creep in Cu Rich Amalgams. G. W. Marshall, E. P.

Lautenschlager, K. Szurgot and S. J. Marshall, Dept. of Biological Materials,Northwestern Univ., Chicago, IL, USA

11:40 In Vitro Corrosion and Tarnish Characterization of Commercials Dental Gold Alloys.T. K. Vaidyanathan and A. Prasad, N.Y. Univ. Dental Center, Dept. of Dental

Materials Science, New York, NY, USA

12:00 Chemical Analysis of NaCI Solutions and Solid Products after Dissolution of Dental

Solders. H. J. Mueller, Northwestern University, Chicago, IL, USA

1

SeSSiOn 3 Kinard Hall, Room 101

CARDIOVASCULAR MATERIALS — I

Session Chairman — A. WESOLOW, St. Raphael Hospital, Yale University,New Haven, CT, USA

10:20 The Present Status of Biomaterials in Poland. E. Rogalski and H. Kus', Institute of

Surgery, Medical Academy of Wroclaw, Wroclaw, POLAND10:40 Protein Coatings for Blood Pump Applications. H. Kambic, R. J. Kiraly, H.

Harasaki, D. Hillegass, Y. Nose', Cleveland Clinic Foundation and Goodyear Tire &

Rubber Co., Cleveland, OH, USA

11:00 Pyrolysis GC-MS as a Technique for Analysis of Retrieved Polymeric Biomaterials.

D. R. Owen, M. B. Hughes and D. Sorenson, Biomedical Engineering Dept.,Tulane University, New Orleans, LA, USA, Flammability Research Center, Univer¬

sity of Utah, Salt Lake City, UT, USA

11:20 Unitized Tri-Leaflet Heart Valve. J. W. Boretos, Biomedical Engineering and In¬

strumentation Branch, Division of Research Services, National Institute of Health,Bethesda, MD, USA

11:40 Electrochemical Assay of Thrombin-Like Enzymes with Electroactive Markers. J. M.

Nigretto and M. Jozefowicz, Laboratoire de Recherche sur les Macromolecules

Universite Paris-Nord, FRANCE12:00 Direct In Vivo Method to Evaluate Flowing Platelets' Affinity for Artificial Surfaces. C.

Baquey, B. Basse-Cathalinat, B. Masson, X. Quancard, G. Janvier, R. Torrielli,A. Beziade, L. Villemin, Inserm (U.53) - Lab. de Physique Nucleaire Applique'e(Univ. Bordeaux II) - C.H.U. de Bordeaux, Domaine de Pellegrin Carreire,Bordeaux-Cedex, FRANCE

2

Session 4

STIMULATED BONE GROWTHSession Chairman — R. W. TREHARNE, Richards Manufacturing Co.,

Memphis, TN, USA

1:30 The Effect of Hydroxyapatite Impregnation on Bonding of Porous Coated Implants. P.

Ducheyne, L. L. Hench, A. Kagan II, M. Martens, J. C. Mulier, Katholieke Univer-

siteit, Leuven, BELGIUM, University of Florida, FL, USA1:50 In Vivo Experimental Results of Piezoelectric Implants. B. Kelly, M. Grether, A. F.

Von Recum, W. W. Coffeen, G. H. Kenner, F. W. Cooke, J. B. Park, Department of

Interdisciplinary Studies, Department of Ceramic Engineering, Clemson University,Clemson, SC, USA

2:10 Enhanced Fixation of Porous Titanium Implants in Cortical Bone Using ElectricalStimulation. S. Colella, R. G. Stang, A. G. Miller, T. G. Stoebe and D. M. Spengler,Dept. of Mining, Metallurgical & Ceramic Engineering and Dept. of Orthopaedics,University of Washington, Seattle, WA, USA

2:30 Effect of Electrical Stimulation on Bone Growth into Porous PMMA And Co-Cr-Mo

Alloy. N. N. Salman, J. B. Park, G. H. Kenner and A. F. Von Recum, Department of

Interdisciplinary Studies, Clemson University, Clemson, SC, USA

2:50 Effects of Low Field Strength Pulsing Electromagnetic Fields On Skeletal Tissue. C.

A. L. Bassett and R. J. Pawluk, Orthopaedic Research Laboratories, College of

Physicians & Surgeons of Columbia University, New York, NY, USA

Session 5BLOOD REACTIONS TO POROUS MATERIALS

Session Chairman — A. F. VON RECUM, Clemson University,Clemson, SC, USA

1:30 Porous Surface Structured Cardiovascular Implants - Improved Thromboresistance

by Growth Limited Surface Endothelialization. R. M. Pilliar, J. D. Bobyn, G. J.

Wilson, W. Lixfeld, D. C. MacGregor, University of Toronto, Toronto, CANADA1:50 Atrial Implant Experiments for Evaluation of Blood Compatible Surfaces—A Prelimi¬

nary Report on Porous Polyurethane Coatings. E. W. Wong, N. S. Ro, W. G.

Williams, B. J. Bellhouse and W. S. Haworth, Ontario Research Foundation,Mississauga, Ontario, CANADA

2:10 Platelet Adhesion to Porous Surfaces. P. K. Predecki, L. Life, P. A. Russell, and M.

M. Newman, University of Denver Research Institute, Denver, CO, USA

2:30 Carbon Surfaced Microporous Membranes: Oxygen Permeability and Interactions

with Blood. H. S. Borovetz, B. P. Griffith, D. D. Mateer, D. M. Hercules, A. D.

Haubold, and R. L. Hardesty, School of Medicine, University of Pittsburgh,Pittsburgh, PA, USA, General Atomic Co., San Diego, CA, USA

2:50 Powder Metal Surfaces as a Blood Interface Material. R. L. Whalen, T. Murakami, K.

Osawa, J. Snow, and Y. Nose, Thermo Electron R&D Center, Waltham, MA, USA,Dept. of Artificial Organs, Cleveland Clinic Foundation, Cleveland, OH, USA

3

Session 6DENTAL IMPLANTS — I

Session Chairman — R. A. DRAUGHN, Medical University of

South Carolina, Charleston, SC, USA

3:30 A Single Blind Study to Compare the Radiographic Assessment and Pocket DepthDetermination of Endosteal Implants. J. H. Sher, A. N. Cranin, M. F, Rabkin, H.

Silverbrand, and N. M. Satler, Brookdale Hospital Medical Center, Dept. of Dental &

Oral Surgery, Linden Blvd. at Brookdale Plaza, Brooklyn, NY, USA

3:50 Mechanical Behavior of a Fibrous Tissue Interface of an Endosseous Dental Implant.J. B. Brunski and R. B. Schock, Center for Biomedical Engineering, Rensselaer

Polytechnic Institute, Troy, NY, USA

4:10 Electron Microscopic Studies on the Tissue-Implant Interface of Single Crystal and

Polycrystal of Alumina — In Vitro and In Vivo. A. Yamagami and H. Kawahara,

Department of Biomaterials and Tissue Culture Center, Osaka Dental University,Kyobashi 1-47, Higashiku, Osaka 540, JAPAN

4:30 Alveolar Ridge Preservation through Direct Hydroxylapatite Implants. H. W.

Denissen, P. J. Klopper and K. de Groot, Dept. of Biomaterials School of Dentistry,Free University, Amsterdam, HOLLAND. Dept. of Exp. Surgery School of Medicine,

University of Amsterdam, HOLLAND

4:50 Oral Tissues Modifications Following Occlusal Traumatogenic Impact on Metal En¬

dosseous Dental Implants in Beagle Dogs. S. Popa, Faculty of Dentistry, Str.

Racovita 60, 3400 Cluj-Napoca, ROMANIA

5:10 Loading of Ceramic-coated Implants to Produce Expansion of the Upper Jaw in

Monkeys. P. Turley, P. Shapiro, and B. Moffett, Department of Orthodontics,

University of Washington, Seattle, WA, USA

Session 7

CARDIOVASCULAR MATERIALS — II

Session Chairman — E. NYILAS, Anco Everett Research

Laboratory, Everett, MA, USA

3:30 A Molecular Level Approach to Blood-Interface Interactions. R. M. Gendreau, R. I.

Leininger, and R. J. Jakobsen, Battelle-Columbus Laboratories, Columbus, OH,

USA

3:50 Mechanisms of Failure in Recovered Vascular Prostheses. A. Wesolow, MercyHospital, RockviHe Centre, NY, USA, Hospital of St. Raphael, New Haven, CT, USA

4:10 Negatively Charged Glutaraldehyde Tanned Bovine Arteries (NCGT), and Human

Umbilical Cords Versus Autogenous Saphenous Vein Grafts - Comparative Experi¬ence. K. Reddy, S. N. Haque, and P. N. Sawyer, The Vascular Surgical Services,

Departments of Surgery and Surgical Research, SUNY, Downstate Medical Center,450 Clarkson Ave., Brooklyn, NY, USA

4:30 Dudley Clotting Test: A Practical Screening Method for Thrombogenicity of Blood

Contact Materials. B. Dudley, J. O'Connell, A. Rumaks, and J. Williams, Becton,Dickinson Research Center, Research Triangle Park, NC, USA

4:50 Systematic Development of Polyurethanes for Biomedical ApplicationsPart I: Synthesis, Structure and Bulk Properties. D. K. Gilding and A. M. Reed,ICI/University of Liverpool Joint Laboratory, Bioengineering Unit, Liverpool L69 3BX,ENGLAND

5:10 Grafted Hydrogel Surfaces and Their Interactions with Tissues. D. K. Gilding, G. F.

Green, J. Wilson, and D. Annis, ICI/University of Liverpool Joint Lab., Bioengineer¬ing Unit, Liverpool L69, 3BX, UK; ICI/Central Toxicology Lab., Alderley Park, Mac¬

clesfield, Cheshire, ENGLAND

4

Session 8KEYNOTE SESSION

FEMORAL NECK FRACTURE FIXATIONTHE TELLTALE NAIL

Session Chairman — J. L. KATZ, Rensselaer Polytechnic Institute,

Troy, NY, USA

8:00 Tutorial Address: "G.L.P.:The Industrial Research View", T. N. Salthouse, Ethicon

Research Foundation, Somerville, NJ, USA

9:00 Keynote Address: "Femoral Neck Fracture Fixation — The Telltale Nail". V. H.

Frankel, University of Washington, Seattle, WA, USA

Session 9HIP IMPLANTS

Session Chairman — P. S. WALKER, Howmedica Inc.,

Rutherford, NJ, USA

10:20 Review of Hip Implant Loosening: Histomorphology of the Bone and Cement Inter¬

face. K. Draenert, Technical University, Munich, W. GERMANY

11:00 The Effect of Prosthesis Orientation and Other Factors on Strain Distribution in the

Femur. F. W. Cooke, D. A. Nagel, D. Burton, E. M. Lunceford, Jr., J. B. Park, A. F.

Von Recum, R. Piziali, V. H. Desai, T. J. Parchinski, and T. Koogle, Clemson

University, Clemson, SC; Moore Clinic, Columbia, SC; Stanford University, Stan¬

ford, CA, USA

11:20 A Study of the Radiological Appearances of the Calcar Femorale after Total HipReplacement Using a Collarless Femoral Component. J. Black, A. L. Sew Hoy, A.

J. C. Lee, R. S. M. Ling, S. S. Vangala, University of Exeter, Devon, UK, P. E. Orth.

Hospital, UK, Dept. of Orthopaedic Surgery, Univ. of Penn., Philadelphia, PA,

USA, Aukland, NEW ZEALAND, University of Exeter, Devon, ENGLAND

11:40 Survivorship Behaviour of Total Hip Replacements. H. S. Dobbs, Dept. of Biomedi¬

cal Engineering, Inst, of Orthopaedics, Middlesex, ENGLAND

12:00 Aluminum Oxide Total Hip Arthroplasty. E. M. Lunceford, A. M. Weinstein, J. J.

Klawitter, P. Griss, Tulane University, New Orleans, LA, USA; Moore Clinic,

Columbia, SC, USA; Lindenhop Clinic, Mannheim, WEST GERMANY

12:20 Cementfree Fixed Hip-Total-Endoprostheses of Carbon - Fibre - Plastic - Com¬

pound - Material in the Femora of Dogs. K. Miller, W. M. Happel, H. P. Fortmeyer,

A. Schmidt, D. Zichner, and P. Prussner, Department of Orthopedic Surgery,

University of Frankfurt, WEST GERMANY

12:40 The Correlation between Acetabular Geometry and the Resulting Pressure Distribu¬

tion. P. D. Rushfeldt, R. W. Mann and W. H. Harris, Massachusetts Institute of

Technology, Boston, MA, USA; Massachusetts General Hospital, Boston, MA, USA

5

Session 10DENTAL IMPLANTS — II

Session Chairman — A. N. CRANIN, Brookdale Hospital,New York University, Brooklyn, NY, USA

10:20 The Effect of Trabecular Structure on Stress Distributions in Bone Around AI2O3 and

LTI Carbon Dental Implants. S. D. Cook, J. J. Klawitter, A. M. Weinstein and

S. Das, Biomaterials Laboratory, Tulane University, New Orleans, LA, USA

10:40 Three Dimensional Finite Element Stress Analysis of LTI Carbon and AI2O3 Blade

Implants. S. D. Cook, J. J. Klawitter, A. M. Weinstein and J. Kent, Biomaterials

Laboratory, Tulane University, New Orleans, LA, USA; Louisiana State UniversitySchool of Dentistry, New Orleans, LA, USA

11:00 The Osteogenic Properties of Carbon When Used as an Intraosseous Implant. A. N.

Cranin, M. F. Rabkin, H. S. Siiverbrand, J. H. Sher, and N. M. Satler, Brookdale

Hospital Medical Center, Brooklyn, NY, USA

11:20 Experience of Vapor Deposited Carbon Coated Tooth Implants in Dogs. S. Michieli,D. Leake, A. Pizzoferrato, and J. Bokros, UCLA Medical Center, Torrance, CA,USA; Rizzoli Inst., Bologna, ITALY; General Atomic Company, San Diego, CA, USA

11:40 Carbon Coated Endosteal Dental Implants in Humans: A Three Year Study. A. N.

Cranin, M. F. Rabkin, H. Siiverbrand, J. H. Sher, and N. M. Satler, Brookdale

Hospital Medical Center, Brooklyn, NY, USA

12:00 Clinical and Histological Evaluation of Porous Titanium and Porous High DensityPolyethylene Tooth Roots. M. Spector, F. A. Young, C. F. Marcinak, and C. H.

Kresch, Medical University of South Carolina, Charleston, SC, USA

12:20 Panel Discussion: Carbon as a Dental Implant Material. Moderator: L. Shulman,Harvard School of Dental Medicine, Boston, MA, USA

6

Session 11ANNUAL BUSINESS MEETINGSOCIETY FOR BIOMATERIALS

Presiding — J. L. KATZ, President, Society for Biomaterials

2:00 BUSINESS MEETING

3:00 STUDENT AWARDS FOR OUTSTANDING RESEARCH

Session Chairman: R. A. JAMES,Loma Linda University, Loma Linda, CA, USA

The Student Awards are presented each year by the Society for Biomaterials for

papers that show outstanding accomplishment in biomaterials research. Papers to be

considered for the 1980 Awards should be sent to: R. A. James, D.D.S., Loma Linda

Univ. SD, Loma Linda, CA, 92345, USA

3:40 Adjourn for Refreshments.

Session 12POLYMETHYLMETHACRYLATE — I

Session Chairman — J. O. GALANTE, Saint Luke's Hospital,University of Illinois, Chicago, IL, USA

4:00 Rheology of Acrylic Bone Cements. W. R. Krause, J. E. Miller, and P. Ng, Montreal

General Hospital and McGill University, Montreal, CANADA4:20 Closed Pressurization of Medullary Cement in Total Hip Replacement. I. Oh, R. B.

Bourne, and W. H. Harris, Orthopaedic Research Laboratory, Massachusetts Gen¬

eral Hospital and Harvard Medical School, Boston, MA, USA

4:40 Bone-Cement Interface Pressure: Comparison of Differing Stem Size and Configura¬tion of Total Hip Femoral Component. R. B. Bourne, I. Oh, and W. H. Harris,Orthopaedic Research Laboratory, Massachusetts General Hospital and HarvardMedical School, Boston, MA, USA

5:00 Prosthetic Fixation Via Pressurized Hydraulic Insertion of Polymethylmethacrylate.L. L. Malcom and F. R. Convery, Division of Orthopedics and Rehabilitation, Univer¬

sity of California, San Diego, CA, USA5:20 Release of Methylmethacrylate Monomer from Bone Cement into Bone under Cyclic

Loading. A. Crugnola, E. J. Ellis, E. L. Radin, and R. M. Rose, University of Lowell, 1

University Avenue, Lowell, MA, USA

7

Session 13PROPERTIES OF

LIGAMENTS AND SKIN

Session Chairman — E. M. LUNCEFORD, JR., Moore Clinic, Columbia, SC, USA

4:00 Aspects of Coated Carbon Fibres in the Ligament-Prostheses. L. Kinzl, D. Wolter,and L. Claes, University of Ulm, Ulm, WEST GERMANY

4:20 Ligament and Tendon Replacement with Absorbable Polymer-Filamentous Carbon

Tissue Scaffolds. H. Alexander, A. B. Weiss, J. R. Parsons, I. D. Strauchler and O.

Gona, Section of Orthopaedic Surgery and Dept. of Anatomy CMDNJ-New JerseyMedical School, Newark, NJ, USA

4:40 A Preliminary Report on the Substitution of Collateral and Anterior Cruciate Liga¬ments by Artifical Fibers. R. J. Pawluk and J. E. Rothermel, Columbia UniversityDept. of Orthopaedic Surgery,Orthopaedic Biomechanics Lab., New York, NY, USA;Dept. of Orthopaedic Surg., Roosevelt Hospital, New York, NY, USA

5:00 A New Possibility of Measuring Absolute Stress and Strain of Ligaments. W.

Mutschler, C. Burri, and L. Claes, Dept. of Traumatology, University of Ulm, Ulm,WEST GERMANY

5:20 Finite Element Analysis of Stresses in Stretched Skin; Comparison with the Tension

Field Theory. P. H. DeHoff, T. S. Bardsley and J. E. Key, University of North Carolina

at Charlotte, Charlotte, NC, USA; Bucknell University, Lewisburg, PA, USA; Marshall

Space Flight Center, Huntsville, AL, USA.

8

Session 14KEYNOTE SESSION

WEAR: FUNDAMENTAL MECHANISMSAND RECENT ADVANCES

Session Chairman — S. F. HULBERT, Rose-Hulman Institute

of Technology, Terre Haute, IN, USA

8:00 Tutorial Address: "G.L.P.: The Academic Research View", J. Autian, Materials

Science Toxicology Laboratory, Univ. of Tennessee Medical Center, Memphis, TN,USA

9:00 Keynote Address: "Wear: Fundamental Mechanisms and Recent Advances".

D. A. Buckley, NASA, Lewis Research Center, Cleveland, OH, USA

Session 15WEAR OF IMPLANT MATERIALS

Session Chairman — A. C. FRAKER, National Bureau of Standards,

Washington, DC, USA

10:20 Design and Statistical Evaluation of a Multistation Sliding Wear Apparatus for In

Vitro Testing of Dental Restoratives. W. F. Bailey, J. F. Johnson, S. L. Rice, M. F.

McSparron, and P. J. Sheth, Institute of Materials Science, The University of

Connecticut, Storrs, CT, USA

10:40 Comparative Wear Studies of Dental Amalgam Using Two Novel Techniques, Laser

Fringe Contouring and Surfometry. J; T. Atkinson, M. J. Lalor, J. B. Cantwell, andJ. F. Jaworzyn, Dept. Mech. Eng., Liverpool Polytechnic, Byrom St., Liverpool L3

3AF, ENGLAND; ICI Corporate Laboratory, Runcorn, ENGLAND

11:00 In Vitro Wear Testing of Total Knee Implants. R. W. Treharne, R. G. Carignan, R.

W. Young, and S. R. Young, Richards Manufacturing Co., Memphis, TN, USA,Materials Technology Corp., Memphis, TN, USA

11:20 Four Years of Wear Testing Experience of Three Joint Simulators. K. W. Greer,

Zimmer, USA, Warsaw, IN, USA11:40 A Simple Joint Simulator for Comparing the Production and Biological Effects of

Metallic Wear Products from Different Hip Prostheses. T. Rae, University of Cam¬

bridge Clinical School, Addenbrooke's Hospital, Cambridge, ENGLAND

12:00 Detection of Debris from Joint Endoprostheses Using Cathodoluminescence and

Microprobe Analysis. H. Plenk, Jr., P. Roschger, and E. M. Horl, Bone Res. Lab.,

Histological-Embryological Institute, Univ. Vienna, AUSTRIA; Metallurg. Inst.,

Studienges. f. Atomenergie, Seibersdorf, AUSTRIA

9

Session 16MECHANICAL PROPERTIES OF

POLYMERS AND COMPOSITES

Session Chairman — JUNE WILSON, ICI Toxicology Laboratory,Macclesfield, Cheshire, UK

10:20 Lifetime Prediction for Biomedical Polymers. G. B. McKenna and R. W. Penn,

Polymer Science and Standards Division, National Bureau of Standards, Washing¬ton, DC, USA

10:40 Biodeterioration of Polymeric Materials. Y. Imai, K. Kojima and E. Masuhara,Institute for Medical and Dental Engineering, Tokyo Medical and Dental University,Tokyo, JAPAN

11:00 Study of Gamma Irradiation Induced Changes in Silicone Elastomer. R. D.

Ainsworth, R. Carmen, R. Guzman, Cutter Laboratories, Biomedical Division, San

Diego, CA, USA; Cutter Laboratories, Berkeley, CA, USA

11:20 Improved Mechanical Properties of Graphite Fiber Reinforced Polymethylmethacry¬late. S. Sana and M. L. Warman, Department of Engineering and Applied Science,Yale University, New Haven, CT, USA

11:40 Fracture Toughness of Carbon Reinforced Bone Cement. W. H. Mueller, H. E.

Groth, and G. Spencer, Department of Engineering and Applied Science, Portland

State University, Portland, OR, USA; Orthopedic Specialists, P.C., Portland, OR,USA

12:00 The Viscoelastic Behavior of a Composite Implant Material by Dynamic Mechanical

Analysis. A. R. Greenberg and R. P. Kusy, Dental Research Center, University of

North Carolina, Chapel Hill, NC, USA

10

Session 17POLYMETHYLMETHACRYLATE — II

Session Chairman — J. B. PARK, Clemson University,Clemson, SC, USA

1:30 Mechanical Strength of Acrylic Cement/Human Bone Interfaces. R. Kusleika and

S. I. Stupp, Northwestern University, Chicago, IL, USA

1:50 Strength and Ingrowth Aspects of Porous Acrylic Bone Cement. J. Ypma, J. de

Wijn, R. Huiskes and T. Slooff, Laboratory for Experimental Orthopaedics, Univer¬

sity of Nijmegen, Department for Dental Materials, University of Nijmegen, THE

NETHERLANDS

2:10 A Second Generation of Acrylic Cements. A. Crugnola, E. J. Ellis, E. L. Radin and

R. M. Rose, University of Lowell, Lowell, MA, USA

2:30 Factors Affecting Surgical Alloy/Bone Cement Interface Adhesion. J. C. Keller, E.

P. Lautenschlager, G. W. Marshall and P. R. Meyer, Jr., Department of BiologicalMaterials, Northwestern University, Chicago, IL, USA

2:50 The Influence of Surface Preparation on the Strength of the Bone-Cement ImplantInterface. S. Raab, A. M. Ahmed, D. Pfeiffer, J. Miller and D. L. Burke, McGill

University and The Montreal General Hospital, Montreal, Quebec, CANADA

Session 18MECHANICAL PROPERTIES OF BONE

Session Chairman — J. L. LERAY, National Institute of Health

and Medical Research, Paris, France

1:30 Correlations between the Mechanical and Physical Properties of Bone. L. E. Claes

and C. Burri, Abt. fur Unfallchirurgie, University of Ulm, Ulm, WEST GERMANY

1:50 Relationalship between Subchondral Bone Density and Failure Load of Metacar¬

pophalangeal Joint. S. Saha, F. Wong, D. Romond and J. Aversa, Dept. of Eng. &

App. Science and Sec. of Orthop. Surgery, Yale University, New Haven, CT, USA

2:10 Sonic Wave Velocity in Bone as an Indicator of Bone Strength. R. A. Douglas, North

Carolina State University, Raleigh, NC, USA

2:30 Mechanical Properties of Equine Cortical Bone. J. E. Anderson, D. D. Moyle and F.

W. Cooke, Dept. of Interdisciplinary Studies, Clemson University, Clemson, SC,USA

2:50 Measurement of Potentials in Bone with and without a Piezoelectric Implant. M.

Grether, B. Kelly, W. W. Coffeen, A. F. Von Recum, G. H. Kenner, F. W. Cooke

and J. B. Park, Department of Interdisciplinary Studies, Dept. of Ceramic Engineer¬

ing, Clemson University, Clemson, SC, USA

11

Session 19ORTHOPEDIC IMPLANTS

Session Chairman — HANNS PLENK, JR, University of Vienna,

Vienna, Austria

3:30 The Evaluation of a Poiycentric Total Knee Arthroplasty. J. J. Klawitter, A. J.

Clemow, M. Milicic, A. M. Weinstein and S. D. Cook, Biomaterials Laboratory,Tulane University, New Orleans, LA, USA; Tulane University School of Medicine,New Orleans, LA, USA

3:50 Evaluation of Wear in the G.U.E.P.A.R. Total Knee Prosthesis. F. J. Kummer and G.

D. Rovere, Howmedica, Inc., Maywood, NJ, USA, Wake Forest University,Winston-Salem, NC, USA

4:10 New Jersey Knee Simulator. M. J. Pappas and F. F. Buechel, Section of Or¬

thopaedic Surgery, CMDNJ - New Jersey Medical School, Mechanical Engineering

Dept., New Jersey Institute of Tech., Newark, NJ, USA

4:30 Cementfree Implanted Knee-Endoprostheses of Different Materials in Animal Exper¬iments. P. Prussner, H. P. Fortmeyer, M. W. Happel, R. Heimel, R. Lade, L.

Zichner, Dept. of Orthopaedic Surgery, University of Frankfurt, WEST GERMANY;Animal Research Laboratory, University of Frankfurt, Frankfurt, WEST GERMANY

4:50 A Quantitative Study of Stress Shielding and Bone Remodeling under Bone Plates. J.

A. Szivek, G. C. Weatherly, R. M. Pilliar, H. U. Cameron, Dept. of Metallurgy &

Material Science, Faculty of Dentistry, Dept. of Surgery, University of Toronto,

Toronto, CANANDA5:10 Torsional Tests of Internal Fixation Plates Made of Different Carbon Fibre Reinforced

Composites. L. E. Claes, C. Burri, L. Kinzl, D. Wolter, E. Fitzer and W. Hiittner,

University of Ulm, Ulm, WEST GERMANY, InstitutfurChemischeTechnik, Universityof Karlsruhe, WEST GERMANY

5:30 A Variable Stiffness, Absorbable Bone Plate. J. R. Parsons, H. Alexander, S. F.

Corcoran, J. Korluk and A. B. Weiss, Section of Orthopaedic Surgery, New JerseyMedical School, Newark, NJ, USA

Session 20POROUS BIOMATERIALS

Session Chairman — G. F. A. HEIMKE, Friedrichsfeld

GmbH, Mannheim, W. Germany

3:30 Interface Mechanics of Porous Ti-6A1 -4V Implants and Bone. A. M. Weinstein, J. J.

Klawitter, J. Anderson, A. Clemow, and J. Koeneman, Biomaterials Laboratory,Tulane University, New Orleans, LA, USA, Lord Corporation, Erie, PA, USA

3:50 Canine Surface Replacement Model: Press-Fit, Cemented and Bone Ingrowth Fixa¬

tion. A. K. Hedley, J. Moreland, R. D. Bloebaum, I. Coster, and I. C. Clarke,Division of Orthopaedic Surgery, UCLA School of Medicine, Los Angeles, CA, USA

4:10 An Evaluation of Functionally Loaded Prostheses Stabilized by Porous High DensityPolyethylene Coatings. B. W. Sauer, R. B. Lade, J. S. Henke, and G. H. Kenner,Orthopaedic Surgery, University of Mississippi Medical Center, Jackson, MS, USA

and Department of Interdisciplinary Studies, Clemson University, Clemson, SC, USA

4:30 Histological and Biomechanical Characterization of the Porous Polysulfone/BoneInterface of Canine Femoral Prostheses Having Porous Surface Coatings.M. Spector, S. L. Harmon, R. J. Davis, and N. J. Ballintyn, Medical University of

South Carolina, Charleston, SC, USA; Union Carbide Corp., Bound Brook, NJ, USA4:50 A Review of the Results of a Microporous Coated Metal Hip Prosthesis. H. U.

Cameron, University of Toronto, Toronto, Ontario, CANADA5:10 Finite Element Stress Analysis of Bone Ingrowth Stablized Hip Joint Prostheses. J. J.

Klawitter, S. D. Cook, A. M. Weinstein, A. J. T. Clemow, and E. M. L iceford,Biomaterials Laboratory, Tulane University, New Orleans, LA, USA; Moote Clinic,Columbia, SC, USA

5:30 Metallic Concentration in Tissue Surrounding Porous Fiber Titanium Implants. C.

Johnson, J. O. Galante, and W. Rostoker, Argonne National Laboratories, Rush

Presbyterian - St. Luke's Hospital, University of Illinois, Circle Campus, IL, USA12

Session 21KEYNOTE SESSION

EPIDERMAL WOUND HEALING,DRESSINGS AND PERCUTANEOUS IMPLANTS

Session Chairman — A. WESOLOW, Saint Raphael Hospital,Yale University, New Haven, CT, USA

8:00 Plenary Session: "Biocompatibility".Chairman: M. Spector, Medical University of South Carolina, Charleston, SC,USA

E. K. Weisburger, National Cancer Institute, Bethesda, MD, USA

9:00 Keynote Address: "Epidermal Wound Healing Dressing and Percutaneous Im¬

plants".G. D. Winter, The Institute of Orthopaedics, Royal National Orthopaedic Hospital,Middlesex, ENGLAND

Session 22METALLIC IMPLANT MATERIALSSession Chairman — H. S. SHIM, Carbomedics Inc.,

San Diego, CA, USA

10:20 The Solution Treatment of Co-Cr-Mo Alloy. A. J. Clemow, B. L. Daniel I, Tulane

University, New Orleans, LA, USA10:40 Fatigue Behavior of Cast Co-Cr-Mo-C Alloy ASTM F75-74. D. O. Cox, Failure

Analysis Associates, Los Angeles, CA, USA11:00 A New Surgical Alloy System I: Intermetallic Precipate Strengthening. H.

Mohammed, Dept. of Dental Biomaterials, College of Dentistry, U. of Fla., Gaines¬

ville, FL, USA11:20 A New Surgical Alloy System II: Co-Cr-Ni-Ta. H. Mohammed and C. Shen, College

of Dentistry, Univ. of Florida, Gainesville, FL, USA11:40 Characterization of Passive Films on 316LVM Stainless Steel. L. N. Gilbertson and

T. Wittberg, Zimmer USA, Warsaw, IN, USA, University of Dayton Research Inst.,

Dayton, OH, USA

12:00 An Analysis of Orthopaedic Screw Fixation Devices. A. M. Weinstein, A.J.T.

Clemow, M. McPhillips-Meade and J.J. Klawitter, Biomaterials Laboratory,Tulane University, New Orleans, LA, USA

13

Session 23BIOCOMPATIBILITY — I

Session Chairman — R. B. BEARD, Drexel University,Philadelphia, PA, USA

10:20 Biological Evaluation of Polymers: II Acute Toxicity Protocols and Relative Toxicityof Diverse Biomaterials. E. O. Dillingham, W. H. Lawrence, J. E. Turner and J.

Autian, Materials Science Toxicology Laboratories, University of Tenn. Center for

the Health Sciences, Memphis, TN, USA

10:40 Tumorgenic Response to Silicone Polymers. M. B. Habal, Department of Surgery,College of Medicine, University of South Florida, Tampa, FL, USA

11:00 Implant Site Infection in Mice Injected with Metal Chlorides. K. Merritt and S. A.

Brown, Lab. for Exp. Surgery, Davos, SWITZERLAND

11:20 Metal Sensitivity and Implants; an In Vitro Test. S. A. Brown, M. B. Mayor and K.

Merritt, Dartmouth Medical School, Hanover, NH, USA

11:40 Intracellular Adaptations at Implant Interfaces Electron Microscopic Studies. T. N.

Salthouse and B.F. Matlaga, Section of Cell Biology, Ethicon Research Founda¬

tion, Somerville, NY, USA

12:00 Electron Microscopic Studies on the Cell— Metal Interface In Vitro and In Vivo. H.

Kawahara, M. Nakamura, A. Yamagami, and Y. Imai, Dept. of Biomaterials andTissue Culture Center, Osaka Dental Univ., Higashiku, Osaka, JAPAN

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Session 24

MATERIALS FORHARD TISSUE RECONSTRUCTION

Session Chairman — G. H. KENNER, Clemson University,Clemson, SC, USA

1:30 An Analysis of In Vivo and In Vitro Biomateriai Properties and Service Characteris¬

tics of Orthopedic Implants. R. F. Hochman, M. Marek, and K. J. Bundy, GeorgiaInstitute of Technology, Atlanta, GA, USA, Johns Hopkins University, Baltimore, MD,USA

1:50 Generalization of Biomechanical Rules for the Fixation of Bone, Joint and Tooth

Replacements. G. Heimke, W. Schulte, P. Griss, P. Schulz, G. Jentschura, Fried-

richsfeld GmbH, Mannheim, Universitat TObingen, Universitat Heidelberg in Mann¬

heim, University Heidelberg, WEST GERMANY2:10 Development and Clinical Application of Alumina Ceramics Implants in the Or¬

thopaedic Field. T. Shikita, K. Takaoka, T. Hosoya, A. Inoue, K. Ono, H. Oonishi,T. Hamaguchi, H. Igaki, H. Kawahara, and M. Hirabayashi, Osaka Univ. Med.

School, Dept. of Orthop. Surg., Osaka Minami Nat. Hosp., Orthop. Dept., Dept. of

Mech. Eng., Univ. of Osaka Pref., Dept. of Dent. Mater., Osaka Dent. Univ., Centr.

Res. Labor, of Kyoto Ceramics Co., JAPAN

2:30 Cranio-Facial Impiantology with Polyrane-Bone Composite. H. B. Habal, J. E.

Maniscalco, D. L. Leake, University of S. Florida, College of Medicine, Tampa, FL,

USA; University of California, Los Angeles-Harbor General Hospital, Los Angeles,CA, USA

2:50 A Poly(2-Hydroxyethyl Methacrylate) Sponge for Restoration of Articular Surfaces.

M. Kon, A. C. De Visser, Dept. of Exp. Surgery, University of Amsterdam, HOL¬

LAND, Dept. of Materials Science, Free University, Amsterdam, HOLLAND

Session 25MATERIALS FOR MAXILLOFACIAL AND

SOFT TISSUE RECONSTRUCTIONSession Chairman — T. M. VALEGA, National Institute

For Dental Research, Bethesda, MD, USA

1:30 Polydimethylsiloxane for Safe and Effective Orofacial Prostheses. I. Biomechanical

Replication of Living Tissue and Pigmented Compositions for Cosmetic Matches with

Spectral Analysis. J. F. Lontz, A. W. Burger and J. W. Schweiger, Maxillofacial

Prosthetic Center, Veterans Administration Center, Wilmington, DE, USA

1:50 Acrylic Elastomers for Extraoral Maxillofacial Prostheses. F. Leonard, E. Selingerand J. J. Urban, George Washington University School of Medicine and Health

Sciences, Washington, DC, USA

2:10 Presurgical Infusion of Proplast: Primate Facial Augmentation. R. Westfall and J.

Kent, Dept. Oral & Maxillofacial Surgery, Louisiana State University Medical Center,

New Orleans, LA, USA

2:30 The Effect of Pore Size on Tissue Ingrowth of Silicone Rubber and Bioelectric

Polyurethane Microporous Implants. R. A. White, R. S. Lawrence, F. M. Hirose and

R. J. Nelson, Los Angeles County Harbor - UCLA Medical Center, Torrance, CA,

USA2:50 The Replacement of the Abdominal Wall by a Carbon-Cloth on Rabbits. R.

Neugebauer, L. Claes, G. Helbing and D. Wolter, Department of Traumatology,

University of Ulm, Ulm, WEST GERMANY

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Session 26BONDING TO HARD TISSUE

Session Chairman — P. DUCHEYNE, Catholic University,Leuven, Belgium

3:30 Bonding to Calcified Tissues through Crystal Growth. D. C. Smith, R. Maijer, G.

Keyes, G. Bennett, and R. Peltoniemi, University of Toronto, Ontario, CANADA3:50 Tissue Reactions to the Calcined Bone Graft. H. Kurosawa and H. Aoki, Department

of Orthopaedic Surg., Institute for Medical & Dental Eng., Faculty of Med. Univ. of

Tokyo, JAPAN4:10 Bone Bonding through Bioadhesives. Present Status. G. Meyer, D. Muster and J. H.

Jaeger, Groupe d'Etudes de Biomecanique Oste'o-Articulaire de Strasbourg,Strasbourg-Cedex, FRANCE

4:30 Glass Ceramic Coated Metallic Implants. H. Broemer, K. Deutscher, G. Exner,G. Fuchs and B. Blencke, Ernst Leitz Wetzlar GmbH, Wetzlar, WEST GERMANY

4:50 Bone Remodeling and Interface after Long-Term Implantation of Glass Ceramic in

the Jaw of Pigs and Humans. U. Gross and V. Strunz, Institute of Pathology andClinic for Maxillo-Facial Surgery, Klinikum, Steglitz, Freie Universitat Berlin, Berlin,WEST GERMANY

Session 27BIOCOMPATIBILITY — II

Session Chairman — S. F. HULBERT, Rose-Hulman Institute

Of Technology, Terre Haute, IN, USA

3:30 Study of Parameters Affecting the Synthetic Material/Tissue Interface

Part II: Biological Response to Negatively Charged Surfaces. J. Wilson, D. K.

Gilding, I. N. Askill and I. S. Pratt, ICI/University of Liverpool, Liverpool, UNITED

KINGDOM; ICI Central Toxicology Lab, Macclesfield, Cheshire, UNITEDKINGDOM3:50 Study of Parameters Affecting the Synthetic Material/Tissue Interface

Part V: Protein Adsorption to Neutral, Positive and Negative Surfaces. G. H. Pigott,D. K. Gilding, I. N. Askill and C. L. Ives, ICI/University of Liverpool, Liverpool,UNITED KINGDOM; ICI Central Toxicology Lab, Macclesfield, Cheshire, UNITED

KINGDOM

4:10 Study of Parameters Affecting the Synthetic Material/Tissue Interface

Part VI: Cell Adhesion to Neutral, Positive and Negatively Charged Surfaces. S. B.

Carter, D. K. Gilding, C. L. Ives and I. N. Askill, ICI/Liverpool University, Liverpool,UNITED KINGDOM; ICI Pharmaceuticals Div„ Macclesfield, Cheshire, UNITED

KINGDOM4:30 Studies of Cell Adhesion to Biomaterials. J. J. Waldburger, T. A. Horbett, B. D.

Ratner, J. J. Rosen and A. S. Hoffman, University of Washington, Seattle, WA, USA

4:50 Systematic Development of Polyurethanes for Biomedical ApplicationsPart II: Surface and Biological Properties. A. M. Reed, D. K. Gilding, J. Wilson and

M. Johnson, JCI/Univ. of Liverpool, Liverpool, UNITED KINGDOM; ICI CTL &

Pharms. Div., Macclesfield, Cheshire, UNITED KINGDOM5:10 Polydimethysiloxane for Safe and Effective Orofacial Prostheses. III. Assessment of

Pigmented Formulation and Fabrication Variables for Toxicity to Human Tissues.J. F. Lontz, I. Mildan and M. D. Nadijcka, Veterans Administration Center, Wilming¬ton, DE, USA

16