Anette Asher October 2011

Processing Human Data – from the Art of Medicine to the Science of Health

September 11

Art of Medicine to the Science of Health

The Art of Medicine and Today’s Vision

The Tipping Point … and it’s getting personal

The Issues: Trusted Information and More Useful Information Moves us to the Sciences of Health

The Pace of Health Information to Sciences of Health

The Future That Will Get Us To Meaningful Use– Computational Individual Predictive Modeling

The Optimal Outcome is Meaningful Use

Anette Asher

September 11

The complexity of modern medicine exceeds the inherent limitations of the unaided human mind. David M. Eddy (1990)

The Century Old Medical Development Cycle

Anette Asher

September 11

Vision without execution is a day dream — Execution without Vision is a nightmare… Japanese proverb

The Global Health Care Vision

Anette Asher

September 11

Medicine as an Art

! Medicine is limited by a shortage of artists and widespread profiteering

! High quality medicine is limited by masters of the art

! A person’s medical & Rx history is usually, inaccurate and incomplete

! Accuracy of Dx is frequently false ±

! The majority of health is managed at the organ level

! Treatments are based upon the artist’s experiences & resources

! Medical diagnostic & therapeutic resources are poorly distributed

! The minority of the world’s people are provided the majority of proper health care Anette Asher

September 11

Health as a Science ! Knowledge of Medicine is widely available via

telemedicine ATM global health network

! High quality and accurate medical care via ATM global health network

! A person’s medical & Rx history is accurate and complete @ PoC

! Dx is accurate via protein disease biomarker signatures

! Health, Dx & Rx are managed at the personal cellular & molecular level

! Treatments are based upon the ATM global health network resources @ PoC

! Medical diagnostic & therapeutic resources are widely distributed

! The world’s majority are provided proper health care

Trusted ICT Convergence into Healthcare

Anette Asher

September 11

Moving Human Data to Wisdom

Anette Asher

Data

Information

Knowledge

Wisdom

From Data to Information to Knowledge to the Wisdom of Life

September 11

From the Art of Medicine to the Science of Health…

Data Information Knowledge Wisdom

2010 the Tipping Point

2020 2000

Art of Medicine at the organ level

Science of Health at the

molecular level

2010

Anette Asher

September 11

The Building Blocks of Life

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Building Blocks of Life Wiring Diagrams of Life

Genetic

Materials

Chemical Materials

Genetic Networks

Chemical Networks

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Anette Asher

September 11

Knowledge of Disease from the Organ to the Cell

! The Life Sciences Research Community ! Doubles its Data Every 3 Months ! Growing Data from Terabytes to Petabytes ! Developing Knowledge of Disease at the Cellular Level ! Advancing Knowledge of Disease to the Molecular Level ! Accelerating the Convergence with Visualization

Disease from the Organ to the Cell Anette Asher

September 11

Trusted Healthcare ICT

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Healthinformatics and Trusting Health IT Anette Asher

September 11

The ICT Governance of Human Data

September 11

A Reference Body

LSIT References IT Standards & Best Practices

http://www.himss.org/asp/topics_FocusDynamic.asp?faid=440

September 11

GIP Encompasses Regulated Institutional Governance

GIP Guidance @ the Core

GIP Guidance Institutional Ecosystem

September 11

Trusting Healthcare ICT

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Good Informatics Practice (G IP) Chapter 1 - Executive Summary A framework for trusted information systems

Ford Winslow, Anette Asher , Steven Fouskarinis, Gabor Fulop, Damian Gomez, Oscar Ghopeh, Andrew Jacobson, John K im, L inda Speake, Mark V ilicich, Howard Asher

http://www.himss.org/content/files/LSITOverviewCh1forwebsite270111.pdf

September 11

Global Health First… Healthcare can achieve Global Equality

Unhealthy people do not remain isolated!

Anette Asher

September 11

Personalized Medicine D-Rx

Novel Diagnostics! CURRENT LIMITATIONS

! R E A L - W O R L D I M PA C T

! PROPOSED SOLUTIONS

T H E R E I M B U R S E M E N T L A N D S C A P E F O R

http://www.bio.org/content/reimbursement-landscape-novel-diagnostics-current-limitations

•  Each Person is Different

•  Each Person with the Same Disease is Different

•  Each Person Responds to the Same Prescription (Rx) Medication Differently

•  One Rx Does Not Fit ALL

•  By matching your Genotype/Phenotype & Biomarker with the Rx Most Compatible with Exact Disease & Genomic Type—Treat the illness, with little or no side effects.

•  Your Personal Genome will become a part of Your Medical Record and Pharmacokinetics @ PoC

Anette Asher

September 11

The Nomic-Sciences of Medicines Personalized

Disease from the Organ to YOUR Cell Anette Asher

September 11

ATM Health Link-for-Life™ Global PHR

Let’s get Personal Health Records

Anette Asher

September 11

Institutional Centric Electronic Medical Record

Institutional Centric EMRs ! Manage the institutional resources for

different patient medical needs. ! Each institution must have EMRs

aligned to their specific clinical work flows & resources to be useful.

! Each patient’s needs are different and the EMR needs to align to different clinical, medical specialty, surgical, laboratory, Rx, radiologic, and billing needs for each specific patient.

! EMRs must be institutional centric to be successful.

Anette Asher

September 11

Individual Centric Personal Health Records

Individual Centric Private PHRs ! Manage the private and personal medical

history and health records belonging to each individual for their specific medical needs.

! Each individual must have their PHRs aligned to their specific medical needs to be useful.

! Each patient’s needs are different and the PHR needs to align to different clinical, medical specialty, surgical, laboratory, Rx, radiologic, and billing needs for each specific individual.

! PHRs must be 24/7 available to the individual accurate, complete, health records, anywhere, anytime they need health care. At point-of-care PoC.

! PHRs must be individual centric to be successful.

Automatically Align to the Credential of Caregiver @ PoC.

Anette Asher

September 11

Institutional Electronic Medical Record Individual Private & Personal Health Records

Mirrored @ PoC

EMR True

Anette Asher

September 11

ATM White Paper Link-for-Life™— a Global Public Health Solutions for we the people.

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http://dl.dropbox.com/u/2204007/Link-for-Life%20Whitepaper.pdf

September 11

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Trusted Health Clouds

http://www.himss.org/ASP/ContentRedirector.asp?ContentID=76169

September 11

Improved Patient Care & Clinical Outcomes

Patient’s Genetic, Dx, Medical & Rx

Records

Personalized Optimal Clinical Protocol

Healthinformatics Clinical

Labs

Clinical Imaging

Optimal Clinical Management Personalized

Medicines Dx – Rx Biomarkers PD –

PK & PV

Disease & Disorder

Regression Progression

Medical Devices, Supplies & Services

PD: Pharmacodynamics (what the drug does to the body) PK: Pharmacokinetics (what the body does to the drug)

PV: Pharmacovigilance (is the pharmacological science relating to the detection, assessment, understanding and prevention of adverse effects)

The Role of Healthinformatics in Health Sciences & Patient Outcomes

Healthonomics drives Health Care Informatics

Health Services Approvals & Reimbursements

Clinical, Urgent, Emergency, Surgical, Critical, Recovery,

Rehabilitation, Follow-up, Referral Services, Outpatient Care

Telediagnostic • Telemedicine • Telesurgical • Teleimaging • Remote Care

Healthonomics

Anette Asher

September 11

The Sciences of Health

X-informatics Modeling ! Computational Predictive Modeling of Disease

Prevention, Intervention & Elimination ! Genetic Remodeling to Optimize Health

! Managing Epidemic & Preventing Pandemic ! Cloud ATM Computing Medical & Health Records

! Translational Evidence-based Health Sciences ! Modeling the Gene/Phenotype of Disease

! Modeling Rx Intervention of Disease From Data to Information to Knowledge to the

Wisdom of Life

Anette Asher

Art of Medicine to the Science of Health Anette Asher

AnetteAsher@me.com

The Global Business of Life